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Takotsubo Cardiomyopathy: A Case of the Broken Heart
Full text linkTakotsubo cardiomyopathy (TC), or broken heart syndrome, is a rare cardiac condition causing temporary left ventricular dysfunction due to severe stress. Though the exact cause is unclear, it mimics myocardial infarction and can lead to cardiogenic shock. Current treatment lacks specific guidelines and relies on heart failure protocols. We report a case of a patient with TC-induced cardiogenic shock, likely triggered by emotional stress. She required vasopressors, a percutaneous intervention, an Impella device, and guideline-directed medication therapies. This case underscores the significance of establishing guideline optimizations for managing TC and cardiogenic shock
Efficacy of Biodegradable Natural fibers Infused Toothbrushes in Plaque Control and Gingival Health: A Double blind Randomized Control Clinical Trial
Full text linkTitle: Efficacy of Biodegradable Natural fibers-Infused Toothbrushes in Plaque Control and Gingival Health: A Comparative Study
Background: Plaque removal is crucial for preventing gingivitis and periodontitis. Biodegradable toothbrushes, infused with natural substances like charcoal and neem, provide an eco-friendly alternative to conventional nylon brushes. Charcoal offers antibacterial properties, while neem provides antimicrobial and anti-inflammatory benefits.
Aim: To evaluate and compare the antiplaque and anti-inflammatory effects of charcoal-infused and neem-infused toothbrushes with conventional toothbrushes.
Methods: This double-blind randomized controlled trial included 33 systemically healthy individuals diagnosed with gingivitis. Baseline plaque scores were set to zero through professional scaling. Subjects were randomly assigned into three groups of 11 each, receiving either a charcoal-infused, neem-infused, or conventional toothbrush. All participants were instructed to use the modified Bass brushing technique twice daily with a standardized toothpaste. Follow-up evaluations were conducted at 7 and 14 days using the Turesky modification of the Quigley Hein Plaque Index for plaque assessment and the Silness and Löe Gingival Index for gingival inflammation. One-way ANOVA with post hoc analysis was used to compare differences between groups, and repeated measures ANOVA assessed parameter changes over time.
Results: The charcoal-infused toothbrush group demonstrated the lowest mean plaque scores, followed by the neem-infused group, while the non-infused group exhibited the highest plaque scores. One-way ANOVA revealed statistically significant differences in plaque scores among the groups at both 7 and 14 days (p\u3c0.05). For gingival index scores, the neem-infused toothbrush group showed the lowest values, followed by the charcoal-infused group, with the non-infused group showing the highest scores. However, these differences were statistically insignificant at both recall intervals.
Conclusion: Charcoal-infused and neem-infused toothbrushes exhibited superior plaque removal compared to non-infused toothbrushes. Although improvements in gingival health were observed, the differences were not statistically significant. Extended trials are recommended to further validate these findings and to explore the potential long-term benefits of using biodegradable toothbrushes.
Clinical Implications: Natural-infused toothbrushes, such as those containing neem and charcoal, may enhance plaque removal and improve oral and systemic health. Their biodegradability offers an eco-friendly alternative to traditional plastic brushes, contributing to sustainability while promoting oral health
Development and Characterization of a Local Drug Delivery System for Endodontic Disinfection and Regeneration
Full text linkHow Hormonal Changes and the Oral Microbiome Interact with Periodontal and Alzheimer’s Disease to Influence Chronic Inflammation and Cognitive Decline?
Full text linkThis review aims to investigate the potential of the bidirectional relationship between Alzheimer’s disease and periodontal disease. The Key players of hormonal fluctuations and microbiome dysbiosis emphasize the shared mechanisms that interplay among both conditions to identify the potential therapeutic opportunities
The Effect of Using Platelet-Rich Fibrin with an Iliac Crest Bone Graft on Alveolar Bone Formation: A Systematic Review
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Fecal Virome Transplantation as treatment for Metabolic Syndrome: A review of current literature Poster for the 11th Annual Roseman Research Symposium
Full text linkFecal Virome Transplantation as treatment for Metabolic Syndrome: A review of current literature Poster for the 11th Annual Roseman Research Symposiu
Disparities in Pap Smear Rates Among Diverse California Populations: A Data-Driven Analysis
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