Himalayan Journal of Health Sciences (HJHS)
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Knowledge, Attitude and Practice of Medical Emergency among Dental and Ayurveda Students
No full textBackground: A medical emergency is a sudden unexpected condition demanding urgent attention and treatment. Medical emergencies require medical attention within one hour which is also known as the “Golden Hour”. Immediate intervention in an emergency can considerably alter the outcome of a patient’s illness and death.
Aim: The aim of study is to evaluate dental and ayurvedic healthcare professional’s knowledge, attitude, and practice.
Materials and methods: The study was conducted among dental and ayurvedic students undergoing under graduation studies through a questionnaire circulated via open link. The data collected was transferred to excel and analyzed using the chi-square test.
Results: Questionnaire were distributed among 150 respondents among which 139 responses were received showing 95.5% dental respondents and 98% of ayurvedic respondents record medical history and drug allergy while only 55% of dental students and 60% ayurvedic students knows to perform BLS (basic life support).
Conclusion: There is a lack of knowledge among participant
Structure-Based Virtual Screening of Small Molecules Targeting Key Proteins of Neisseria gonorrhoeae
No full textObjectives: To identify potential small molecule inhibitors against key resistance-associated proteins of Neisseria gonorrhoeae using a molecular docking-based virtual screening approach, addressing the urgent need for novel therapeutics in light of rising drug resistance.
Materials and Methods A computational study employing virtual screening of phytochemicals and standard antibiotics against selected N. gonorrhoeae proteins using SwissDock and CB-Dock, followed by interaction analysis through Discovery Studio Visualizer.
Interventions. Docking of 30 structurally diverse phytochemicals and four standard antibiotics against four essential proteins of N. gonorrhoeae: Penicillin-binding Protein 2 (PBP2; PDB ID: 3equ), Hypothetical Protein with bound ppGpp (PDB ID: 5vog), Adhesin Complex Protein (PDB ID: 6gq4)
Main Outcome Measures: Evaluation of binding affinities, docking scores, and molecular interaction patterns to determine the most promising small molecule inhibitors.
Results: Several phytochemicals exhibited strong binding affinities and favorable interactions with the target proteins, in some cases outperforming standard antibiotics. Detailed interaction profiles revealed key residues involved in ligand binding and supported the potential of selected compounds as inhibitors.
Conclusion: The in silico findings highlight promising phytochemical candidates for further experimental validation. These results contribute to the development of novel therapeutic strategies to combat extensively drug-resistant N. gonorrhoeae strains and support the role of natural compounds in antimicrobial drug discovery
Ayurvedic Review on Classical Preparation Methods of Rasa Drugs
No full textAyurveda employs a variety of ideas with the aim of creating a healthy society through disease treatment and prevention. In ancient Rasashastra, for instance, mercury was mined for use as a medicine base, and Rasashatra is one of the branches of Ayurveda that deals with the art of alchemy. Rasa-Aushadhi refers to the medicines which are prepared, and classified under the alchemy discipline where medications are processed through Murchana, Rodhana, Jarana and Mardana along with Shodhana. These methods purify substances, improve their therapeutic power and enhances therapeutic window of Rasa-Aushadhi. This paper highlights the understanding of Ras Dravyas and significance of their preparatory methods
Concept of Avarana; Role in Disease and its Diagnostic Importance in Ayurveda
No full textAvarana is a unique and important Ayurvedic concept that describes the pathogenetic route of a number of ailments. Accurate analysis and therapeutic application require a deep comprehension of its underlying principles. Avarana is similar to many clinical disorders, but because of insufficient clinical understanding, it is frequently misdiagnosed. As a result, standard therapeutic approaches may not yield the intended results when treating a variety of Vata-dominant illnesses. In Ayurveda, Avarana is a disease-specific concept and successful treatment outcomes of related diseases depend on the proper identification and management of Avarana. The main cause of the disorder is the vitiation of Vata Dosha, which becomes blocked and then serves as a catalyst for a number of disease processes. Avarana Vata must be accurately diagnosed and well managed because an incorrect diagnosis might result in ineffective therapeutic measures and worsen the disease
Concept of Marana and Jarana and their Role in Rasashastra: A Review
No full textRasashastra is the other name for science of mercury which is a part of Ayurveda. Rasashastra in both preventive as well as therapeutics has their importance. It deals with Rasa dravyas. Rasashastra works around the origin of the Rasa dravyas, their physical and chemical properties and classifications, with therapeutic benefits of these substances as well as about their applications. Metals and minerals are subjected to certain treatments before they are made fit for internal administration. One such process is called Marana, which is incineration of metals, making them into a form that cannot be returned to their original metallic state. Since metals are not assimilable in their natural state, it is necessary to process them into finer forms so that they can easily pass into the adipose tissue for absorption. Marana successfully eliminates the original physical properties of the metal while maximizing its therapeutic potential so that no toxic effects are left. Similarly Jarana is performed as transition procedure of Rasa Shastra, which is carried out before the performance of Marana procedures with metals like Vanga, Yashada and Naga. This article described concept and significance of Marana and Jarana procedures in Rasashastra
Ayurvedic concept of Vega, Role of Vegadharana in disease and its Treatment approaches
No full textAyurveda is not merely an ancient health system but also an art of living that aims towards the well being of all aspects of life. The major goal of Ayurveda is the maintenance of health among the healthy. As maintaining health is a top priority, Acharya Charaka formulated Swasthya Chatushka as a cardinal concept. This concept described several aspects related to the physical and mental well being. Vega is one such aspect which referred to natural instincts, considered crucial to the upkeep of body balance. The process of forcibly repressing these natural instincts is called Vega Dharana, which is harmful to health. Ayurveda divides such instincts into two types as Dharaniya Vega and Adharaniya Vega. First one is repressible instincts and later one is un-repressible instincts. Dharaniya Vega consists of mental and emotional desires while Adharaniya Vega consists of physiological desires like defecation, ejaculation, urination, passing gas, sneezing, yawning and vomiting, etc. The suppression of Adharaniya Vega may lead some pathological events inside the body thus these physiological desires should not be suppressed. This article brings to light the relationship between Vega Dharana and related diseases along with their therapeutic approaches
Role of Ayurveda in Global Health w.s.r. to Physical, Mental and Moral well-being
No full textAyurveda, the ancient medical science of India, not only deals with bodily diseases but also with psychological disorders. In Ayurveda, the mind performs functions such as reasoning, conceptualization and thinking. The principles of Ayurveda and Yoga are thought to be a good method of relieving mental suffering by balancing the mind with the soul. Ayurveda also addresses psychosomatic diseases such as Bhayaj, Shokaj Jwara, Atisara, Manas Arochaka Chhardi. These physical and mental ailments can be addressed with various Ayurvedic practices such as meditation, Svasthavritta, Yoga, Dinacharya, Ritucharya, Shamana, Shodhana, Svedana and Snehana. Ayurvedic preventive and therapeutic interventions help in the restoration of physical, mental, moral and spiritual health. This article explore role of Ayurveda in global health with special emphasis to physical, mental and moral well being
Consumer behaviour towards Ayurvedic products in India
Get PDFAyurveda is a traditional Indian system of medicine that focuses on holistic health and balance through natural remedies, diet, and lifestyle practices. Many skin and hair care products are available in the Indian markets. Yet, consumers are confused with brand authenticity, 100% natural or not? Reliability of the quality in the absence of proper third-party verification. This study examines this intriguing domain by probing consumer perceptions, experiences, and their ability to discern authentic natural products from those containing synthetic chemicals. The study is based on both primary and secondary data. Primary data is collected through structured questionnaires from a cross-section of 260 households in year 2022, and secondary data is collected from the Amazon ratings. The results of the primary survey show that 58% of respondents said they were unsure whether the ayurvedic or herbal hair and skin care products they use contain chemical ingredients. Results of the secondary survey show that purchasing decisions are not made solely based on a product's chemical-free ingredients; other considerations also play a role. Overall, higher share of five-star rating for ayurvedic products, indicates consumers are happy about the products, however, the market concentration for the ayurvedic products is high, and there is a good scope for new entrants into the market
Kansya Bhasma and Swarna Bhasma: Pharmacological Properties and Ayurvedic Applications
No full textAnidra (Insomnia) is recognized as an independent disease, or in some texts it is mentioned as a prodromal symptom of other conditions such as; Visha Lakshanas, Angamarda, Tandra, Shiro Roga, Akshigaurav and Arishta. Heaviness in eyes, polymyalgia, drowsiness and headaches, etc. are major side effects associated with Anidra. Medical science offers several options for the management of such conditions; similarly, Ayurveda also put great emphasis for its management. Pharmacological drugs as well as Panchakarma therapies such as-Brimhana Chikitsa, Sirahtarpana, Akshitarpana and Nasyaare mainly described by Ayurveda philosopher for the management of insomnia. Among these, the role of Nasya therapy is explained in this article. In this therapy, medication is administered through the nose, which is considered one of the routes for delivering medication to the head region, serving as a gateway to the brain and central nervous system. Nasya gives beneficial results, such as lightness in head, refreshing sleep, cheerful mind, improvement in function of sense organs and normalization of metabolic activity, etc
A Systematic Review on Ethnobotany and Bioactive Compounds of the Genus Ipomoea (Convolvulaceae)
Get PDFThis systematic review focuses on the therapeutic properties of the Ipomoea genus by examining its bioactive components and ethnobotanical uses. The review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The project compiles indigenous information from many regions worldwide regarding the medicinal uses of Ipomoea species, serving as a basis for future research and the advancement of pharmaceutical endeavors. Among the 4297 studies identified in the study, only 152 met the criteria for inclusion. The species that was most commonly employed was Ipomoea batatas (L.) Lam; it was utilized for the treatment of diabetes, along with other medical ailments. The genus encompasses a diverse array of ailments, including cancer, diabetes, dermatological disorders, and gastrointestinal disorders. Ipomoea species possess bioactive compounds that have anti-inflammatory, antibacterial, antioxidant, and anticancer properties. Further investigation is necessary to scientifically validate the medicinal capabilities of these plants and their bioactive constituents. This study should encompass clinical trials and complete pharmacological assessments while also upholding appropriate consumption practices and respecting indigenous knowledge