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“Formulasi Dan Karakterisasi Hidrogel Ekstrak Daun Dadap Serep (Erythrina folium) Dalam Bentuk Plester Sebagai Penurun Demam”.
No full textFever is a condition where the body temperature is more than 37.5oC, fever
can also be an early clinical manifestation of a certain infection. Efforts to
overcome the fever begins with self-medication that is with sympathetic
treatment. Dadap plant is a plant that examines many properties as traditional
medicine, but this plant can only be found in certain regions. Efforts should be
made to create new innovations in preparations that can provide convenience to
the community by making hydrogel preparations with natural ingredients namely
leaf dadap serep which is efficacious in treating fever.
The population in this study was the Dadap leaf extract hydrogel. The
spare dadap leaf was taken in Tulung Village, Sampung District, Ponorogo
Regency. This research was carried out by making three hydrogel formulas of
Dadap leaf extract spare with a composition of every 30 g of preparations
containing Dadap leaf extract F1 for 2.5 g; F2 for 5 g, and F3 for 10 g. From the
three formulas, the physical properties of the hydrogel were analyzed to see the
characterization of the hydrogel which included organoleptic test, pH test,
viscosity test, homogeneity test and temperature drop test in mice test animals
The results of the three hydrogel formula extracts of Dadap's leaf extracts
are F1, F2 and F3 have the same characterization, they are semi-solid shape,
characteristic odor and green color, hydrogel pH is 6.0-6.5, viscosity 170,000-
236,000 cP and homogeneous. In the temperature reduction test with mice test
animals effective on the hydrogel formula Dadap leaf extract with a composition
of every 30 g of preparations containing leaves extracts of Dadap spare 5 g and
10 g
Keywords: hydrogel, fever, dadap leaf extract serep
UJI AKTIVITAS ANTIBAKTERI EKSTRAK CACING DAN KAPSUL CACING TANAH (Lumbricus rubellus) TERHADAP PERTUMBUHAN BAKTERI Salmonella Thyposa, Eschericia coli, dan Staphylococcus aureus DENGAN METODE DIFUSI AGAR
No full textOne type of earthworm that is ofte
n used in medicine is Lumbricus
rubellus. Contains high
enough protein and
produce a bacterial controller
called Lumbricin I. Lumbricin I has broad
-
s
pectrum
antimicrobial activity,
which can inhibit the growth of gram
-
positive and gram
-
negative bacteria
.
Objectives
:
to tes
t whether or not the ability of
antibacterial substances from extracts
of worms and
earthworm capsules
(Lumbricus rubellus) against
Salmonella
Thyposa, Escherichia coli, and
Staphylococcus aureus bacteria
.
Methods
:
using diffu
sion method to use cylinders Of
various
concentrations. The results of the
inhibit zone diameter residence
around the cylinder will be processed
using one way ANOV
A statistic (O
ne
Way ANOVA) with SPSS completion.
Results:
With a different
sample treatment without boiling and without suspended with 0.97% NaCl extract of worms and
earthworm capsules (Lumbricus rubellus) can not inhibit the growth of bacteria Salmonella
thyposa,
Eschericia coli and Staphylococcus aur
eus with the diffusion method.
Conclusions and suggestions:
Based on the results of data analysi
s obtained the conclusion: With
sample treatment different from
without boiling and without suspension wi
th
NaCl
0.97% worm extract and earthworm capsule
(Lumbricus rubellus) cannot inhibit the growth of Salmonella thyposa, Eschericia coli andStaphylococcus
aureus bacteria by agar diffusion metho
PENETAPAN KADAR ETANOL PADA ARAK JOWO YANG BEREDAR DI WILAYAH PONOROGO PADA BULAN JANUARI–MARET 2019 DENGAN METODE KROMATOGRAFI GAS
No full textThere are several cases related to the abuse of Arak Jowo liquor in Ponorogo Regency. Currently,
many people around that abuse by mixing liquor with various other types of drinks, to take lives.
Objective
: to
deter
mine the ethanol content in jowo wine. Sampling in this study using random sampling at the Ponorogo Police
Station.
Method
: Determination of ethanol content was carried out using the Gas Chromatography method with the
optimization results of initial temper
ature of 50oC then held for 5 minutes and increased the temperature of 200oC
with a final time of 25 minutes, injector temperature used 260oC and detector temperature of 300oC. The compound
used as an internal standard is n
-
propanol.
Results
:
T
he sample ob
tained from the Ponorogo Police Station
containing ethanol with the results of the determination of the ethanol content from a sampling of 3 bottles obtained
levels as much as 42.84%, 38.77% and 35.31%.
Conclusions and suggestions
:
Arak Jowo
contains a lar
ge amount
of ethanol. It is necessary to determine the levels of other compounds found in Arak Jowo that circulate in Ponorogo
Regency so that the percentage levels can be kno
UJI CEMARAN MIKROBA PADA INFUS SESUDAH PAKAI DENGAN METODE ANGKA LEMPENG TOTAL (ALT) DAN ANGKA KAPANG KHAMIR (AKK) DI RUMAH SAKIT “Y” DI PONOROGO “
Full text linkUsed Infusion is infusio
n that has been used by the patient by inserting a liquid that contain of drug into the body by
an intravenous route at a constant rate over a period of time. In addition, the management of used infusion that is
less precise can causing the growth of micro
organisms that are harmful to the health of patients and other
employees.
Objective
: To determine the presence of microbial contamination and the amount of microbial
contamination in infusion after use in the "Y" hospital in Ponorogo.
Method:
Used infusion
samples taken at the "Y"
hospital in Ponorogo by purposive sampling. Microbial testing uses the Total Plate Number (ALT) and the Fungal
Fungus Number (AKK) while the data analysis in this study uses the Standard Deviation technique. Results Based
on the r
esults of the study, the Total Plate Value for infusion after use is 2.25 x 102 colonies / ml or 225 colony / ml
and Value of Mushroom Fungus 1.5 x 101 colony / ml or 15 colonies / ml.
Conclusions and suggestions:
After
-
use
infusions used in this study exp
erienced microbial and fungal contamination and it is hoped that more attention
must be paid to ways of handling further medical waste so as not to endanger officers, sufferers, visitors or the
community around the hospita
“Uji Kelembaban Kulit Tubuh Pada Lulur Minyak Zaitun Yang Ditambah Tepung Beras Putih”
No full textIndonesia is one of the tropical countries, displaying strong sunlight can
be used for some skin problems such as dry skin. Therefore a cosmetic
preparation is needed that can reduce dry skin problems. This study aims to
analyze olive oil and scrub oil which added white rice flour to the skin's body
moisture. The sample is women who have income of 20 to 25 years. The tool used
is the Bia Skin Analyzer tool.
The research data collected in the analysis using two-way ANOVA test.
Based on the results of the data, proving that the use of scrubs gives higher yields
compared to the scrub of oil added with white rice flour.
In the oil scrub, there was a 1.4% increase in scrub oil which added
white rice flour to occur 1.33%, so the difference was 0.67%. In the ANOVA test,
it was found that F calculated 1,211 and F table 2,68, the significant value of
sample was 0,309 and the significant tax distribution F was 0,05. So, the show of
white rice on scrub oil does not provide significant strength
Keywords: Body Scrub, Olive Oil, White Rice Flour, Moisture
“Uji Mutu Tepung Biji Durian Sebagai Bahan Pangan Alternatif Berdasarkan Kadar Air dan Kadar Abu Serta Cemaran Mikroba”
No full textDurian (Durio zibethinus murr) is a fruit that is very popular in Indonesia.
During this time, part of the fruit of the durian which is more commonly consumed
fruit or salute were part of the flesh. The percentage of the weight of this section
include low only 20-35%. This means the skin (60-75%) and seeds (5-15%) have
not been fullest utilized. Raw durian seeds are not edible because it contains fatty
acids syclopropene which is toxic, how to cope with the presence of these
compounds is by sulfatation (stream of sulfuric compounds in fats) or by warming
high, so the cluster of syclopropene will be off. Raw durian seeds can be processed
in the form of flour and used as a substitute material as a source of carbohydrates,
durian seeds because in there as much as 43.6 grams of carbohydrates per 100
grams. This research aims to make a durian seed flour and do a test to find out
organoleptic, moisture content, ash and microbial impurities levels based on
National standard of Indonesia No. 3751 year 2009 including organoleptic,
moisture content ≤ 14.5%, ash content ≤ 0.70%, ALT ≤ 106
and 104 ≤ AKK.
Some of the methods used in this study, i.e., gravimetric water content by the
method of gray levels, gravimetric methods, test of microbial impurities with ALT
method as much as 25-250 colonies/g are calculated and AKK 10-150 as many
colonies/g are calculated . After having obtained the data from tests conducted then
compared directly with data requirements.
The quality of the test results can be stated that the durian seed flour quality
meets the requirements of National standard of Indonesia No. 3751 year 2009
except the grey levels. Durian seed flour products P1 has the organoleptic results
powder form, peculiar smell, brown color, moisture content 8.594%, ash content
3.693%, ALT 135 x 102
colonies/g, AKK 0 colonies/g. P2 has the organoleptic
results powder form, peculiar smell, light brown color, moisture content 8.598%,
ash content 3.473%, ALT 9.5 x 101
colony/gram, AKK 28 x 102
colonies/g. P3 has
the organoleptic results powder form, peculiar smell, brown color, moisture content
6.782%, ash content 3.527%, ALT 194 x 101
colony/gram, AKK 11 x 101
colony/gram. The test results of each of the products does not exceed the levels of
the test results, the moisture content does not exceed the maximum rate of 14.5%,
ALT test results does not exceed the maximum limit of 106
and test results does not
exceed the maximum limit of AKK 104
, while the result exceeds the maximum
levels of ash content 0.70 %.
Keywords: durian seed flour, organoleptic, moisture content, ash content, ALT,
AK
“Uji Mutu Simplisia Temulawak (Curcuma xanthorrhiza Roxb.) di Salah Satu Desa di Kecamatan Slahung”.
No full textSimplisia was developed by local farmers with the simplicia-making method
traditionally and based on experience (empirical). The water content of ginger
rhizome when harvested ranges from 75% -80%, this figure is quite high so that
this commodity is easily damaged if it is not immediately processed or dried.
Researchers conducted a study on the quality of temulawak simplicia in one
village in Slahung District, Ponorogo Regency. Quality testing is carried out in
accordance with the Indonesian Herbal Pharmacopoeia Edition I of 2008 and the
Regulation of the Republic of Indonesia Drug and Food Supervisory Agency
Number 12 of 2014 concerning Quality Requirements for Traditional Medicines.
In this test a sample of temulawak simplicia was used by accidentally
taking. The population of the ginger simplicia in one of the villages in Slahung
Subdistrict, Ponorogo Regency. Examination of these samples was carried out by
drying shrinkage test, total ash test, acid insoluble ash content test, water soluble
extract test, ethanol soluble extract test, volatile oil content test, curcuminoid
content test, moisture content test, and microbiology test.
From the experimental results obtained drying shrinkage test of 15,65%,
total ash content test of 5,85%, acid insoluble ash content test of 1,53%, test levels
of water soluble extracts of 6,97% and 5,8%, assay levels of soluble ethanol
extracts of 2.3% and 2.5%, test of volatile oil content of 1,3% and 2%,
curcuminoid levels of 0,94% and 1,08%, water content test of 15,65% and
15,54%, total plate number test has a value of 25,1 x 105 colonies / gram and
22,85 x 105 colonies / gram, and test the number yeast mold has a value of 1 x 103
colonies / gram and 2 x 103 colonies / grams. Based on the Regulation of the Head
of the Republic of Indonesia Food and Drug Supervisory Agency Number 12 of
2014 concerning the Requirements for Quality of Traditional Medicines and
Indonesian Herbal Pharmacopoeia Edition I in 2008 for the yeast fungus test
sample the temulawak simplicia met the requirements while for drying shrinkage
test, total ash content test, level test acid-insoluble ash, water soluble extract test,
ethanol soluble extract test, volatile oil content test, curcuminoid content test,
moisture content test, and total plate number test for temulawak simplicia samples
did not meet the requirements.
Keywords: quality test, simplicia, ginge
“Pemeriksaan Angka Lempeng Total (ALT) Dan Most Probable Number (MPN) Bakteri Escherichia coli Pada Es Batu Balok Dan Es Batu Kristal”.
No full textIce cubes are widely used by the community. Ice cubes made from water that
is frozen. For making ice cubes from raw water and boiled water. Ice cubes that are
on the market are not necessarily safe for consumption that the quality is low and
there are many bacteria are one bacteria i.e. Escherichia coli. The bacterium
Escherichia coli is can cause a variety of diseases such as diarrhea, nausea and
vomiting. Thus, the need for quality checks in terms of Microbiology, based on ice
cubes. This research was conducted on a test to see the value of the number Plate and
Most Probable Number of bacteria Escherichia coli on ice cubes ice crystal stones
and beams in accordance with SNI 7388:2009 about a maximum Microbial
Impurities in Food i.e. ALT 1 x 10-4 colonies/ml and MPN< 2 colonies/ml.
On the research of qualitative testing was performed in the form of a
quantitative form of ALT and MPN. Data obtained after the test Number Plate and
Most Probable Number. Furthermore the number of bacteria is calculated by the
calculation of the 30-300 colony for Number Plate Total (ALT) and for the Most
Probable Number (MPN) views on the tables of MPN.
From the results obtained as a result of the number of Total Plate on a sample
block of ice cubes is 4511.67 colonies/ml sample on ice and rock crystal was 3378.33
colonies/ml. Of the Total Plate Number results for samples of ice cubes Ice and rock
crystal beams meet the terms. Most Probabel Number of bacteria Escherichia coli on
ice cubes beams is 31 colonies/g and ice cubes are crystal 7 colonies/g. From the
results of the Most Probable Number in the sample did not qualify based on ISO
7388:2009 Limit of Microbial Contamination in Food namely ALT 1 x 10-4
colonies/g and MPN < 3/g.
Keywords: Ice Cubes and Ice Crystal, Total Plate Count, Most Probable Numbe
Uji Cemaran Mikroba pada Ekstrak Kayu Manis (Cinnamomun burmani) Produksi Wilayah Jenangan Ponorogo dengan Metode ALT dan AKK
No full textCinnamon has been used and processed into herbal medicine. One herbal
product is herbal medicine with liquid dosage forms produced by CV.Sjri Songgo
Langgit namely Cinnamomun burmani (Cinnamomun burmani) Liquid Extract.
This product has been widely consumed but has not been widely marketed. Because
it has never been tested for quality. The purpose of this study was to determine the
microbial product quality using the ALT and AKK methods.
This study uses 3 types of samples that are made in 1 week on 3 different
days. The samples used were 9 bottle samples, each sample contained 600 ml. The
method used is ALT and AKK. ALT to determine the number of bacteria and for
AKK to find out the number of fungi.
Based on the results of the experiment data obtained conclusions: (1) The
total number of plates on Cinnamomun burmani 3787.67 colony / ml of liquid
extract. (2) The total number of plates on Cinnamomun burmani 547.5 colony / ml
liquid extract. (3) On testing the total plate count on Cinnamomun burmani liquid
extract fulfills the requirements. On testing the yeast mold figure on Cinnamomun
burmani liquid extract fulfilling the regulatory requirements of the Supervisory
Board of the Republic of Indonesia Food and Drug Supervisory Agency No. 12 of
2014 concerning Requirements for Quality of Traditional Medicines.
Key words: Cinnamon Liquid Extract (Cinnamomun burmani). ALT, AK
Peningkatan Jumlah Cemaran Mikroba pada Maskara Merek “X” dengan Waktu Penggunaan Berdasarkan Angka Lempeng Total (ALT).
No full textMascara is a cosmetic product that can thicken, flex, blacken eyelashes.
Cosmetic eyelash makeup that is used in the long term can lead to contamination
of microbial contamination, it is influenced by the lack of maintaining cleanliness
during use, storage, poor use, and use of mascara more than once. Therefore the
researchers tested how the increase in the amount of microbial contamination in
mascara with the time of use for fourteen consecutive days. according to BPOM
RI Number HK.03. 1.23.07.11.6662. In 2011 the total plate number requirement is
5 x 102 colonies / ml.
The population in this test is the "x" brand mascara in one of the Ponorogo
supermarkets by taking it randomly. The number of samples used in the study
were ten packaging. Five new product packaging, tested using the Total Plate
Number to find out whether the product contamination meets the requirements or
not. If the ALT test results meet the requirements, then continued the test of
increasing microbial contamination by taking five packs of the same brand
mascara used by five different volunteers. Use by rubbing on the right and left
lashes twice for 14 consecutive days.
From the experimental results, the total plate number in the new product
sample is 3,34 x 102
colonies / ml. Further testing, the test of increasing microbial
contamination obtained results of B1 samples 3,5 x 102 colonies / ml, B2 samples
7,5 x 102 colonies / ml, B3 samples 7,0 x 102
colonies / ml, B4 samples 3,9x102
colonies/ ml, and B5 4,0 x 102 colonies / ml sample. Based on the requirements of
BPOM RI Number HK.03. 1.23.07.11.6662. In 2011 the amount of Microbial
Contamination in new product mascara was declared as eligible. While the test for
increasing microbial contamination in mascara used by five volunteers 60%
fulfilled the requirements and 40% did not meet the requirements. Thus it can be
concluded that the mascara product is still feasible to be reused after fourteen
times of use
Keywords: Microbial Contamination, Mascara, AL