International Journal of Public Health Science (IJPHS)
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Influence of croscarmellose in fast disintegrating tablet of Syzygium polyanthum extract
Get PDFBay leaves (Syzygium polyanthum) contain the flavonoid quercetin which can be used as an antihyperlipidemic drug. The development of antihyperlipidemic drug formula in the form of fast disintegrating tablet (FDT) is needed for patients who experience dysphagia. FDT preparations require an optimal super disintegrant concentration to produce a good drug formula. This study aims to develop the FDT formula of bay leaves extract using the super disintegrant croscarmellose sodium (CCS) intra and extra-granular. FDT formulation using the wet granulation method with variations of CCS concentrations; F1: 2%, F2: 3.5%, and F3: 5% for extra granular, and 2% for intra granular. The formulation process, in-process control (IPC) granules, weight uniformity tests, and various physical properties tests of tablets were carried out. Data were statistically analyzed using one way ANOVA test (α=95%). The results of statistical tests of IPC granules, uniformity of weight, and tablet size of all FDT formulas were not significantly different (p>0.05). The CCS concentration for extra granular significantly affected the wetting time, disintegration time, hardness, and the value of friability percentage of FDT (p<0.05). The combination of intra and extra-granular CCS (2%:5%) gave the most optimum physical properties of bay leaf extract FDT
Influence of behavioral and genetic variables on the prevalence of type 2 diabetes mellitus in middle-aged monks of Thailand
Get PDFDiabetes mellitus (DM) and its associated complications present a major health problem for the Thai people, including Buddhist monks. This study aimed to identify the influence of behavioural and genetic variables on the prevalence of type 2 diabetes mellitus in middle-aged monks of Thailand. The study analyzed data from the health data centre of the Department of Public Health, Thailand, focusing on middle-aged monks in 76 provinces across 12 regions. The study recruited 6,408 Thai monks who met inclusion and exclusion criteria between October 2015-November 2019. Multivariable analysis was performed using a generalized linear mixed model, with adjusted odds ratios and 95% confidence intervals reported at a significance level of 0.05. Our study found that among the middle-aged monks of Thailand, 7.12% (95% CI: 6.49-7.78) had diabetes mellitus out of a total of 6,408. The results of our multivariable analysis showed that the following factors were associated with diabetes mellitus in monks of Thailand: respondents’ body mass index (BMI) ≥30 kg/m2 (AOR=4.26, 95% CI: 3.08-5.90, p-value <0.001), respondents with a family history of DM (AOR=3.37, 95% CI: 2.52-4.81, p-value<0.001), and respondent’s age ranges of 55-59 (AOR=2.87, 95% CI: 2.26-3.84, p-value<0.001), respectively. Diabetes millatus is significantly associated with the respondents who were obese, aged, and had a family history of DM. Therefore, a regular DM screening program as well as a timely health monitoring system for monks will enhance the diabetes control program in reducing the DM burden in Thailand
Dengue hemorrhagic fever prediction in coastal area using geographically weighted regression
Get PDFDengue hemorrhagic fever (DHF) is still a health problem globally, including in Indonesia. Geographical and climatic conditions in coastal areas are different from other areas, which may impact differences in environmental risk factors for dengue. This study aims to create a prediction model for the incidence of DHF in coastal areas. The research was conducted in Bantul Regency, Indonesia, involving data from 2015-2019. Dengue incidence data were collected from the health office. Climatic data were from climatology station. Data on altitude and shoreline distance were obtained by geographic information system (GIS) processing. Population density and wide settlement area are obtained from the Bureau of Statistics. The geographically weighted regression (GWR) analysis was carried out using GWR4. The results showed that GWR with a weighting of Fixed Bi-Square Kernel obtained an R2 value of 0.7768, better than the global model (R2 0.5254). It indicates that DHF (Y) in Bantul Regency is 77.68% determined by population density (X1), altitude (X2), settlement area (X3), shoreline distance (X4) and rainfall (X5) and the remaining 22.32% are influenced by other variables which are not investigated. Geographically, the predictor variables explain the DHF incidence with a strong category in the central region, and weak in coastal area
Prevalence of COVID-19 vaccines side effects among health care workers in Kirkuk City, Iraq
Get PDFFrequent local and general side effects were revealed after vaccination with COVID-19 vaccine, which played a role in public confidence in and acceptance of the vaccine since the evidence source for the safety of the vaccines and their side effects were exclusively provided only from manufacturer-funded researches. This study aimed to assess the prevalence of COVID-19 vaccines side effects among health care workers in Kirkuk City, Iraq. This cross-sectional study was done in governmental hospitals in Kirkuk City/Iraq from May 7, 2022 to August 15, 2022 among 373 healthcare workers (only those who were vaccinated with the COVID-19 vaccine). The data were analyzed through the statistical package for social sciences (SPSS) program version 23.0. Total of 246 (66%) healthcare workers experienced at least one side effect following the COVID-19 vaccination. Reported side effects among females were higher (70.1%) than males (60.4%) and they were a little higher (67.2%) among participants with age ≤40 years. The most repeated side effects were general fatigue, injection site pain, and headache. In conclusion the majority of the reported side effects were mild to moderate in severity and not considered life-threatening. The rate of COVID-19 side effects was lower among the participants who received Sinopharm's COVID-19 vaccine in comparison to others vaccines
The impact of bullying and cyberbullying on mental health: a systematic review
Get PDFBullying, including cyberbullying, has a devastating impact on mental health, particularly among adolescents. This literature study aims to identify mental health issues caused by bullying and cyberbullying. A systematic review was conducted in the last five years using the keywords "bullying, cyberbullying, mental health, adolescent" and the population, intervention, comparison, outcome, study design (PICOS) framework within Scopus (29 articles), ProQuest (187 articles), Science Direct (193 articles), and SAGE (58 articles) published databases in the last five years using the keywords of “bullying, cyberbullying, mental health, adolescent”. The selected articles are those applying quantitative and longitudinal studies published in 2018-2022 in which study participants were adolescents who had experiences as victims of bullying and cyberbullying. The 25 articles met the inclusion criteria for review. Based on the results of the review of the article, it was found that mental health problems can occur in all roles in bullying and cyberbullying, but the highest is in the role of victim. Mental health problems that occur in victims include anxiety, stress, depression, low self-esteem, suicidal ideation, and suicide attempts. Based on these results, different interventions are needed for the roles involved in bullying and cyberbullying, especially for victims, because psychological problems are more common in victims
Review of global burden of disease studies: trends, challenges, and future directions
Get PDFGlobal burden of disease (GBD) studies plays an important role in assessing the variability of risk factors, injuries, and diseases worldwide, providing essential evidence for policy-making and healthcare planning. This study presents a review of current literature on GBD studies, aiming to analyze the trends, challenges, and future directions in this field. We conducted a review of published GBD studies from inception to date, utilizing major scientific databases and relevant sources. Our findings reveal several noteworthy trends in GBD studies. Over the years, GBD studies have expanded to cover a wider range of diseases and risk factors, providing a more comprehensive understanding of global health. Advances in data availability, technology, and modeling techniques have improved the accuracy of disease burden estimates. The inclusion of disability-adjusted life years (DALYs) has enabled comparisons as well as prioritization of interventions. However, challenges remain, such as limited data in middle and low-income countries and methodological complexities. The COVID-19 pandemic has emphasized the need for responsive methodologies. Future directions include strengthening data collection, utilizing machine learning, big data analytics, ethical use of artificial intelligence and promoting collaboration for consistent GBD studies
Knowledge and practices of private healthcare providers regarding tuberculosis case notification in Rural Maharashtra
Get PDFIndia carries the highest share of active and missing tuberculosis (TB) cases globally. The Government of India is prioritizing private sector engagement (PSE) in TB elimination activities, as most healthcare-seeking in the country happens in this sector. This study aimed to understand the knowledge and practices of private healthcare providers (PHP) on various aspects of TB case notification through the National TB Elimination Programme (NTEP). This cross-sectional study was carried out between Oct 2020 to April 2021 amongst PHPs in the Junnar Tuberculosis Unit (TU), Pune District, Maharashtra. Junnar Block has 299 PHPs who assess, diagnose, and/or treat TB cases. A total of 97 participants were enrolled in the study. About 89 (91.8%) PHPs are aware that TB case notifications are mandatory by law. However, 80.4% are unaware of the Ni-kshay portal (web-based case surveillance system) by NTEP. Similarly, 74 (76.3%) must be aware of incentives for PHPs to collaborate with the government healthcare delivery system. 82.8% of total Ayurveda, Unani, Naturopathy, Siddha, and Homeopathy (AYUSH) practitioners and 46.2% of Allopathic practitioners have poor knowledge about TB case notification, with a Chi-square value of 14.36 (p<0.01). Our study shows that the active engagement of private providers (PPs), especially AYUSH practitioners in rural areas, is a need of the hour in achieving TB elimination
Awareness of Phymill treatment for cerebral palsy kids among university students’ perspective
Get PDFCerebral palsy (CP) kids are a group of disorders that affect their mobility. This health condition is somewhat of a crucial disability and requires treatment to have a better lifestyle as they grow older. It is important to acknowledge the existence of this CP and ways to battle or treat it. Currently, the physio-treadmill (PhyMill) is well developed for CP kids. In this study, we focus on a quantitative survey that was conducted to predictors of the knowledge towards CP and PhyMill among university students, and to observe the awareness of the treatment based on ergonomics, biomechanics, and safety aspects using the PhyMill. The results showed that a huge percentage of students are aware of the knowledge of CP and how to know if an individual is experiencing this disability. The responses for the function of PhyMill have shown the students that the function of the PhyMill is to stimulate the conditioning of a healthier lifestyle in patients with this health condition. The responsive feedback of treatment on ergonomics, biomechanics, and safety aspects also shows comfortable, user-friendly, and good safety inventions by using PhyMill. The significance of this study is would explore the possibility of PhyMill to enhance the performance of patient treatment
The effect of lavender aromatherapy and deep breathing exercise on anxietas level in hemodialysis patients
Get PDFChronic kidney failure is a chronic disease that requires treatment and hemodialysis therapy. Hemodialysis therapy has physical and psychological impacts on patients, such as stress. Patients who experience stress require management techniques such as lavender aromatherapy and deep breathing relaxation. The purpose of the study was to compare the effects of lavender aromatherapy and deep breathing relaxation on patients receiving hemodialysis who were experiencing the stress of chronic kidney failure. The study's quasi-experimental design includes two groups for the pretest and posttest. The 32 patients with chronic renal failure receiving hemodialysis made up the research sample; 16 of them participated in the lavender aromatherapy intervention and 16 were part of the deep breathing relaxation group. The research instrument used is the perceived stress scale (PSS) questionnaire. With a p-value of 0.000, data analysis employing an independent t-test reveals a difference between the deep breathing relaxation and lavender aromatherapy interventions on the stress of chronic renal failure patients receiving hemodialysis. Lavender aromatherapy and breathing relaxation can reduce stress in chronic kidney failure patients undergoing hemodialysis. Lavender aromatherapy reduces stress in chronic kidney failure patients more effectively than deep breathing relaxation. Lavender aromatherapy can be an alternative therapy to reduce stress while undergoing hemodialysis
The psychological impact of the COVID-19 epidemic among healthcare workers at the grassroots level in Vietnam
Get PDFThe COVID-19 pandemic has significantly affected the mental health of healthcare workers (HCWs). Therefore, an immediate priority is to monitor rates of mental health issues to understand related factors and inform interventions. The main purpose of this study was to evaluate the psychological and mental health impact of COVID-19 and some related factors among HCWs at the grassroots level in Vietnam. A cross-sectional study was conducted on 675 HCWs working at health facilities through questionnaires. The finding showed the rate of HCWs who were psychologically affected by the COVID-19 pandemic was 37.2%, of which 64.1% of HCWs were afraid to tell their families about the risk of exposure to COVID-19 at work. The 31.0% of HCWs had difficulty sleeping deeply/insomnia due to the COVID-19 epidemic. No statistically significant differences were found in the psychological impact of COVID-19 between HCW groups by age, gender, seniority, and professional qualifications. Some groups of HCWs were found to have poor psychological health. Our research suggests that during the COVID-19 pandemic, HCWs working in healthcare facilities experienced an increased psychological burden; psychological interventions for those at high risk and with common mental disorders should be included to reduce this burden and protect HCWs' mental health