Bezmialem Vakıf Üniversitesi Kurumsal Akademik Arşiv
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Comparing the Neuroprotective Effects of Telmisartan, Perindopril, and Nebivolol Against Lipopolysaccharide-Induced Injury in Neuron-Like Cells.
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Nazal dekonjestanların maksiller sinü mukozasındaki antibiyotik konsantrasyonuna etkisi
No full textNazal dekonjestanların maksiller sinü mukozasındaki antibiyotik konsantrasyonuna etkis
The effects of hydroxyethyl starch and gelatine on lung tissue and coagulation during the resuscitation of rats with traumatic haemorrhagic shock
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Thorax computed tomography findings and anti-SARS-CoV-2 immunoglobulin G levels in polymerase chain reaction-negative probable COVID-19 cases.
No full textOBJECTIVE: This study aimed to evaluate the SARS-CoV-2 immunoglobulin G (IgG) levels after 6 months of polymerase chain reaction (PCR) negativebut assumed to be COVID-19 positive cases to investigate the relationship between IgG levels and thoracic computed tomography (CT) findings.METHODS: This was a single-center study that included patients whose PCR test results were negative at least three times using nasopharyngealswabs but had clinical findings of COVID-19 and thoracic CT findings compatible with viral pneumonia. Six months after discharge, the IgG antibodieswere analyzed. The cutoff value for negative and positive serology was defined as <1.4 (index S/C) and ≥1.4 (index S/C), respectively. In addition, thepatients were categorized according to their thoracic CT findings as high (typical) and low (atypical). Also, the patients were grouped into classes as<5% lung involvement versus ≥5% lung involvement.RESULTS: The patients’ mean age was 49.78±12.96 years. PCR was negative, but patients with COVID-19 symptoms who had SARS-CoV-2 IgGpositive were 81.9% (n=95). The antibody titer and lung involvement ≥5% were statistically significantly higher in SARS-CoV-2 IgG positive cases(p<0.001 and p=0.021). Age and chest CT findings were the risk factors for lung involvement (OR=1.08, p<0.001 and OR=2.19, p=0.010, respectively).CONCLUSION: This study is valuable because increasing severity (≥5%) of lung involvement appears to be associated with high and persistent IgGantibody titers. In probable cases of COVID-19, even if the PCR test is negative, high IgG titers 6 months after discharge can predict the rate of lungparenchymal involvement
EAHIL 2022 Konferansı İzlenimleri, Rotterdam, Hollanda, 1-3 Haziran 2022
No full textBu çalışmada, 1-3 Haziran 2022 tarihinde \"Broaden The Horizons - diversity, partnership and innovation with a human touch (Ufukları genişletmek: insan dokunuşuyla çeşitlilik, ortaklık ve yenilik)\" teması ile Hollanda’nın Rotterdam şehrinde düzenlenen EAHIL 2022 Konferansı izlenimleri meslektaşlarımızla paylaşılacaktır. Organizasyon hibrit formatta düzenlenerek katılımcılara çevrimiçi katılım sağlayabilme imkanı da sunulmuştur. Çalışma ile birlikte 12-16 Haziran tarihlerinde Norveç’in Trondheim şehrinde düzenlenecek olan EAHIL 2023 Çalıştayına katılım sağlamak isteyen meslektaşlarımıza ilham olması hedeflenmiştir
Evaluation of pediatric patients presenting with acute-onset unilateral transient acquired blepharoptosis
No full textPurpose: To evaluate the clinical features of pediatric patients with acute-onset, unilateral transient acquired blepharoptosis.
Methods: In this retrospective study, the clinical records of patients between April 2015 and June 2020 were reviewed for evaluation of demographic features, accompanying neurological and ophthalmologic manifestations, symptom duration, etiological cause, and imaging findings. Patients with congenital and acquired blepharoptosis with chronic etiologies were excluded.
Results: Sixteen pediatric patients (10 boys and 6 girls) with acquired acute-onset unilateral transient blepharoptosis were included in this study. The patients' mean age was 6.93 ± 3.16 years. The most commonly identified etiological cause was trauma in 7 patients (43.75%) and infection (para-infection) in 5 patients (31.25%). In addition, Miller Fisher syndrome, Horner syndrome secondary to neuroblastoma, acquired Brown's syndrome, and pseudotumor cerebri were identified as etiological causes in one patient each. Additional ocular findings accompanied blepharoptosis in 7 patients (58.33%). Blepharoptosis spontaneously resolved, without treatment, in all the patients, except those with Miller Fisher syndrome, neuroblastoma, and pseudotumor cerebri. None of the patients required surgical treatment and had ocular morbidities such as amblyopia.
Conclusion: This study demonstrated that acute-onset unilateral transient blepharoptosis, which is rare in childhood, may regress without the need for surgical treatment in the pediatric population. However, serious pathologies that require treatment may present with blepharoptosis
