DR-NTU (Data) (Nanyang Technological University)
DR-NTU (Data) (Nanyang Technological University)Not a member yet
1955 research outputs found
Sort by
Related Data for: Experimental realization of a SU(3) color-orbit coupling in an ultracold gas
No full textData for "Experimental realization of color-orbit coupling in an ultracold gas
Replication Data for: Ocean acidification in Southeast Asia: a multiannual time series of carbonate system variability in the central Sunda Shelf Sea
No full textThis dataset contains time series data and analysis codes for seawater carbonate system parameters and other ancillary biogeochemical and physical variables of seawater in the Singapore Strai
Replication Data for: An initial assessment of volcanic meteo-tsunami hazard in the South China Sea:what we learned and how to move forward
No full textIn this work, we simulated volcanic meteo-tsunamis from four different locations in the South China Sea, Celebes Sea and northern Philippines Sea, using different eruption intensity scenarios. The goal was to have a first assessment of volcanic meteo-tsunami hazard for countries surrounding the South China Sea. For the simulations, we used the publicly available code FUNWAVE, which we modified for volcanic meteo-tsunamis for our selected source locations. Here we report the timeseries results for the 16 synthetic wave gauges placed around the South China Sea
Replication Data for: Observation of helical pulses
No full textSimulation code for space-time helical pulses, experimental dat
Discourse_datasets_NLP
No full textCleaned discourse datasets (with feature scores where appropriate) for downstreamed NLP/ML task
Ultrasound Responsive Nanotherapeutics for Multimodal Reprogramming of Obese Fat
No full textObesity remains a major global health challenge due to the lack of therapeutic strategies that directly address the complex multifactorial pathology of obese adipose tissue. Here, we present a translatable nanotherapeutic strategy that enables targeted and holistic remodeling of obese white adipose tissue (WAT) through a triple-modality approach combining sonothermal, nitric oxide (NO), and nanocatalytic therapy based on gold nanoparticles functionalized with S-nitrosothiols (SNO@AuNP). Serving as an antenna to harvest ultrasound energy and a mimic to antioxidant enzymes, SNO@AuNP produces localized mild-hyperthermia, releases a therapeutic level of NO, and scavenges reactive oxygen species (ROS), whereby inducing browning and breaking the vicious couplings between oxidative stress, hypoxia, and inflammation in obese WAT. In a high-fat-diet-induced obese mouse model, this synergistic therapy significantly reduced the targeted subcutaneous WAT (60.1%) and the remote visceral WAT (62.2%) within 18 days, essentially relieved obesity-associated type 2 diabetes, and significantly attenuated hyperlipidemia, systemic oxidative stress, and inflammation. The interconnected intracellular, paracrine, and endocrine signaling pathways underlying the treatment were elucidated, offering mechanistic insights for developing effective approaches for obesity and its metabolic complications
Replication Data for: Metallic electro-optic effect in gapped bilayer graphene
No full textData files for figures in "Metallic electro-optic effect in gapped bilayer graphene
Enterococcus faecalis redox metabolism activates the unfolded protein response to impair wound healing
No full textEnterococcus faecalis is an opportunistic pathogen that thrives in biofilm-associated infections and delays wound healing, yet how it impairs host tissue responses is unclear. Here, we identified extracellular electron transport (EET) as a previously unrecognized source of ROS in E. faecalis and show that this activity directly triggers the unfolded protein response (UPR) in epithelial cells and delays epithelial cell migration. ROS detoxification with catalase suppressed E. faecalis-induced UPR and rescued epithelial cell migration, while exogenous H2O2 was sufficient to restore UPR activation in EET-deficient strains. Importantly, UPR disruption by pharmacological inhibition also impaired cell migration, highlighting a critical role for UPR homeostasis in wound repair. Our findings establish EET as a novel virulence mechanism that links bacterial redox metabolism to host cell stress and impaired repair, offering new avenues for therapeutic intervention in chronic infections
Sustainable Finance: ESG/CSR, Firm Value, and Investment Returns
No full textData for journals analyze