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AcaEngWritGPT:A personal Socratic mentor for university students specifically designed to give feedback on academic English writing in terms of style, language, structure, argumentation, and writing from sources. It aims to promote critical reflection, transparency, and constructive guidance.
No full textIncreasing incidence of serotype 38 invasive pneumococcal disease driven by the ST393 clone among children, Denmark 2022–2024
Full text linkNon-vaccine-serotypes (non-VT) pose a challenge to reducing invasive pneumococcal disease (IPD). Since 2023, serotype 38 IPD has increased in Denmark promoting investigation of this serotype’s characteristics. We included all non-VT IPD cases from 2014 to 2024 to calculate annual incidences per 100,000 individuals with 95% confidence intervals (CI). Clinical characteristics and outcomes of serotype 38 IPD were compared with other non-VT IPD in 2022 to 2024. Incidence of serotype 38 IPD increased mainly in children < 2 years, from 0.87 (95% CI 0.02–4.84) to 5.99 (95% CI 2.41–12.34) cases per 100,000 population, whereas the incidence for other non-VT remained stable. SNP analysis, conducted for serotype 38 isolates, revealed that the rise was driven by the ST393 clone with isolates not linked to a region or outbreak. Baseline characteristics and outcomes were similar between the 42 cases of serotype 38 IPD and the 412 other non-VT IPD cases, except for age distribution (p < 0.001) with serotype 38 IPD more frequent in children aged < 2 years (21.4% vs. 3.4%). In conclusion, serotype 38 IPD, driven by the ST393 clone, was the dominant serotype causing non-VT IPD in children < 2 years the last two years, however disease severity was similar to other non-VT IPD
Engaging with engagement:Ethnographic sensitivity in the sociology of regimes of engagement
Full text linkThis article investigates an overlooked question: what kind of methodological sensitivity is necessary when using Laurent Thévenot's sociology of regimes of engagement (SRE) in ethnographic research? Thévenot's call to study proximate forms of engagement ‘below’ the public correlates with the recent turn to non-representational methodologies in ethnography. Thus, we discuss the methodological consequences of the ontological commitment of SRE through a dialogue with the epistemological arguments of non-representation, which we take to include sensory, affective, and embodied ethnographies. We do so by zooming in on three key aspects of SRE: plurality of different regimes of engagement, investment of people in their environment to secure goods, and versatility between trusting and doubtful engagements. We argue that while SRE and non-representational ethnography share a concern for unspoken, affective, and embodied practices, SRE requires a different sensitivity towards the dynamics between the representational and non-representational
EU skal styrke samarbejdet med Taiwan - med eller uden Trump
No full textKinas invasion eller blokade af Taiwan kan være rykket tættere på. Taiwans ekspræsident Tsai Ing-Wen deltager i Copenhagen Democracy Summit den 13.-14. maj. Stærke kinesiske protester forventes
Guidance and background information for long-term monitoring of the Peregrine Falcon in South Greenland
No full textThe Peregrine Falcon has become a prominent indicator of environmental conditions across the world. In particular, the Peregrine has played a prominent role in detecting unintended side effects of chemical compounds accumulating in the environment. More recently, changing climatic conditions are also reflected in Peregrine populations and the falcons are included as focal species in Arctic Council's Circumpolar Biodiversity Monitoring Programme (CBMP) for the terrestrial environment. Long-term monitoring efforts are necessary to identify changes and the Peregrine monitoring in South Greenland, initiated in 1981, is rare in its coverage of more than four decades. In line with the 2022 Greenland National Research Strategy, it is now time for Greenland Institute of Natural Resources (GINR) to take over and institutionalise the monitoring – and ensure that the databases and know-how accumulated over decades is available for comparative studieslong into the future. Hence, this guidance document aims to support a continuation and possible expansion of the Peregrine Falcon monitoring so Greenland can continue to meet the commitments to CBMP, and maintain a sampling routine to help identify changes in occurrence of environmental pollutants, with implications for wildlife as well as humans on a global scale.The field efforts in South Greenland 1981-2023 have been conducted on a volunteer basis, or as part of Søren Møller’s limited allocation of research time from Roskilde University Library. We are grateful to the numerous dedicated volunteers who over the decades have shared the thrills of observing the magnificent Peregrines as well as endured rains and storms in dinghieson choppy waters or cramped into small tents.1 The field work has depended on invaluable logistical assistance from individuals and organisations in the survey area, and financial grants from a range of private and public foundations.2 Lastly, the process of transferring data and know-how to Greenland – and further exploring and developing monitoring opportunities of the Peregrine population – was made possible thanks to a generous support to GINR from Aage V. Charity Foundation 2023-2028
The dominance of the English language as a challenge for the field of Early Childhood Education and Care
Full text linkCharacterization of small extracellular vesicles from ovarian cancer patients and pre-diagnostic patient samples:Evidence from the Danish blood donor study
Full text linkAim Ovarian cancer (OC) is the leading cause of gynecological cancer deaths. Current biomarkers of OC are not specific or sensitive enough. Extracellular vesicles (EVs), EV surface proteins and their cargo microRNA (miRNA) show potential as biomarkers. This study aimed to characterize the ability of EVs to identify early OC-biomarkers among blood donors six months before their diagnosis. Methods Study groups of OC patients, benign tumor patients (B), healthy blood donors (Control), and blood donors with incident OC diagnosis within six months of the last blood draw (Pre-diagnostic; PD) were established. Small EVs were enriched from plasma using ultracentrifugation. EVs were characterized by Dynamic Light Scattering (DLS), EV Array, NanoFlow Cytometry, Nanoparticle Tracking Analysis, and Western blots. RNA from EVs was isolated. A discovery study was performed on OC and B patients using the TaqMan Array Human MicroRNA A card. A validation study of 9 specific miRNAs was performed using RT-qPCR. Results With DLS, it was identified that the OC patients’ EVs were more heterogeneous in size compared to the other groups. Western blot identified CD63 and TSG101 in the EV enrichments. EV Array assessed 22 known protein biomarkers. TaqMan MicroRNA Array cards indicated a differential miRNA abundance between OC and B; however, technical replication and validation could not validate this pattern. Conclusion This study has analyzed EVs in OC, B, Control, and PD women. More extensive investigations of EV CD9, CD151, and CD81 in conjunction with other risk factors and well-known biomarkers like CA125 or HE4 should be the main objectives of future research
The qualitative quotient:the importance of applying mixed methods to understand circularity of hospital plastics
Full text linkThe healthcare sector, while aiming to protect human health and wellbeing, has a significant negative impact on the climate and environment due to massive resource use and waste production. The circular economy (CE), designed to preserve resources in closed-loop value chains, has gained global attention yet lacks practical implementation. This perspective paper discusses the challenges of implementing CE initiatives for single-use plastics (SUPs) in hospitals, with a specific emphasis on practitioner involvement. With a departure in the scientific literature on SUPs in hospitals, which shows to primarily use quantitative methods, such as life cycle assessments and waste audits, this paper suggests using mixed methods to access the day-to-day reality of medical staff and their unique insights on healthcare practices. Lastly, we suggest integrating social elements into CE initiatives at the micro level (e.i. in practice), drawing inspiration from the wellbeing economy
Benefits Slippage:The Yearlong Process of Implementing Electronic Document Management in a Danish Municipality
Full text linkGovernment institutions invest substantial resources in digitalizing their processes and services. To benefit from these investments, the expected benefits must be specified and systematically pursued. Otherwise, they will likely slip. Benefits slippage is the situation where specified benefits do not materialize even though they continue to be seen as, at least partially, realizable. This study investigates benefits slippage in the implementation of electronic document management in a municipality in Denmark. On the basis of interviews, we identify three reasons why benefits slipped. First, inactionable benefits specifications make it difficult to see the link between the specified benefits and the work-process changes necessary to realize them, thereby leaving staff without directions about what changes to implement. Second, a prolonged realization process increases the opportunity for external events to disrupt the process, thereby shifting attention to other matters before the benefits have been realized. Third, absent benefits follow-up leaves the status of benefits realization uncertain or ignores indications that benefits have not been realized, thereby prolonging or discontinuing the realization process. In the studied municipality, the specified benefits had slipped for three years. Future research should investigate how benefits-realization initiatives can be resumed late, locally, and at low cost.Government institutions invest substantial resources in digitalizing their processes and services. To benefit from these investments, the expected benefits must be specified and systematically pursued. Otherwise, they will likelyslip. Benefits slippage is the situation where specified benefits do not materialize even though they continue to be seen as, at least partially, realizable. This study investigates benefits slippage in the implementation of electronicdocument management in a municipality in Denmark. On the basis of interviews, we identify three reasons why benefits slipped. First, inactionable benefits specifications make it difficult to see the link between the specifiedbenefits and the work-process changes necessary to realize them, thereby leaving staff without directions about what changes to implement. Second, a prolonged realization process increases the opportunity for external events to disrupt the process, thereby shifting attention to other matters before the benefits have been realized. Third, absent benefits follow-up leaves the status of benefits realization uncertain or ignores indications that benefits have not been realized, thereby prolonging or discontinuing the realization process. In the studied municipality, the specified benefits had slipped for three years. Future research should investigate how benefits-realization initiatives can be resumed late, locally, and at low cos