University of Oviedo

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    74227 research outputs found

    Análisis de la función inmunitaria y su relevancia en modelos murinos de envejecimiento acelerado

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    Tesis doctoral con mención internacionalEsta Tesis Doctoral se centra en investigar las alteraciones sistémicas e inmunológicas en dos modelos murinos del Síndrome de Progeria de Hutchinson-Gilford (HGPS), LmnaG609G/G609G y Zmpste24-/-, con el objetivo de identificar nuevos factores que promueven el envejecimiento prematuro y su similitud con el envejecimiento fisiológico. Para este fin, realizamos un análisis global del proteoma del plasma en estos modelos, identificando factores circulantes desregulados que podrían servir como biomarcadores potenciales o dianas terapéuticas para aliviar los síntomas del envejecimiento prematuro

    Conocimientos y actitudes sobre los cuidados al final de la vida de los profesionales de enfermería

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    En la última década, el papel de los cuidados paliativos y al final de la vida ha cobrado una relevancia creciente en el ámbito de la atención sanitaria. Aunque los avances en la medicina moderna han permitido un progreso considerable en el tratamiento y curación de múltiples enfermedades, un número significativo de personas sigue afectado por enfermedades crónicas y sin cura conocida, como las patologías cardiovasculares, enfermedades respiratorias crónicas, trastornos degenerativos y cáncer, las cuales tienen un impacto considerable en la calidad de vida diaria de los pacientes

    Modelling and application of bucking restrained braces for performance-based earthquake engineering frameworks

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    Open access funding provided by Politecnico di Bari within the CRUI-CARE Agreement

    Global trends of trait matching in avian frugivory and its consequences for the complementarity and irreplaceability of birds

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    Ministry of Science and Innovation, Spain, Juan de la Cierva Incorporacion [IJC2020- 043765- I]; Government of the Asturias Principality, REWILDING project, FEDER, GRUPIN [AYUD/2021/51261]; National Agency for the Promotion of Research, Technological Development and Innovation (Argentina) [PICT 2018- 01566

    Assessing the impact of the new mexico cable car on air pollution

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    The impact of traffic on air quality has prompted many cities to implement policies such as driving and parking restrictions, congestion fees, or investing in public transport infrastructure. This paper focuses on the effects on pollution levels of a new cable car system in Mexico City, a very polluted megalopoly. This cable car system provides transportation to historically marginalized communities situated in a mountainous area at an altitude high enough to make metro connectivity impossible. The study uses official NO2 level data to estimate a Diff-inDiff model. The results show a drop in NO2 levels of approximately 13 % not only in the stations closest to the Cablebus, but also in areas located further away. Our results suggest that the potential environmental benefits of new green transport infrastructures should be taken into account by policymakers when making decisions related to public transit systems.Open Access funding was provided through the CRUE-CSIC agreement with Elsevier. Juan Prieto Rodriguez reports that financial support was provided by the Agencia Estatal de Investigacion ´ del Gobierno de Espana ˜ (grant #PID2022-137352NB-C43) Rafael Salas reports financial support from the Agencia Estatal de Investigacion ´ del Gobierno de Espana ˜ (grant #PID2022-137352NB-C43). Maria Jose PerezVilladoniga reports financial support was provided by the Agencia Estatal de Investigacion ´ del Gobierno de Espana ˜ (grant #PID2020- 115183RB-C21). Juan Prieto-Rodriguez and Maria Jose PerezVilladoniga are members of the CULTURALITY project, funded by the European Commission (HORIZON-CL2-2023-HERITAGE-0110113262)

    Análisis de Clases Latentes con JAMOVI (Latent Class Analysis, LCA)

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    Guía para el Análisis de Clases Latentes. JAMOVIEl Análisis de Clases Latentes (ACL) es una metodología ampliamente utilizada en las ciencias del comportamiento para identificar estructuras latentes subyacentes en datos observacionales. Perteneciente a la familia de los modelos de variables latentes, el ACL permite clasificar individuos o casos en grupos no observables directamente, denominados clases latentes

    Mechanical Beam Steering Reflectarray Antennas Using Focal Arc Geometries: Performance and Limitations

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    EuCAP (2025. Stockholm, Sweden)This paper presents a parametric study on passive, mechanically steerable reflectarray (RA) antennas using a tilted focal arc configuration. The objective is to examine the trade-offs in designing compact RA systems capable of steering beams over a wide angular range while minimizing scan losses. Multiple RA designs at 29.5 GHz are evaluated, featuring varying degrees of compactness and steering ranges with highly uniform gain across the steering range. Performance is assessed in terms of gain and aperture efficiency, highlighting the effects of focal ratio and steering range on these metrics. A prototype antenna is also manufactured and measured, validating the simulation results with a demonstrated scan loss of only 0.5 dB over a 90-degree range and a maximum gain of 28.2 dBi. The findings provide insights into the design compromises required for passive, mechanically steerable RA systems, offering guidelines for optimizing such antennas for mm-Wave applications.This work was supported in part by MICIN/AEI/10.13039/501100011033 within the projects PID2020-114172RB-C21, PID2023-146246OB-C32 and TED2021-130650B-C22, cofounded by UE (European Union) ”NextGenerationEU”/PRTR.; and by Ministerio de Educación y Formación Profesional under grant FPU20/07267

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