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Simulations of pulse propagation in optical fibers using graphics processor units
No full textEmbargado hasta 01/01/2100Several simple cases of pulse propagation in optical fibers have been simulated using a graphics processor unit. Comparisons with simulations in a computer processor unit are also reported. Speedups from 4 to 36 have been obtained by different numerical methods, reaching a similar accuracy both in computer processor unit and in graphics processor unit, working with double-precision floating point numbers. Best results are achieved in simulations when the number of points in t grid rises. Therefore, the results indicate that graphics processor units could be a good tool to improve numerical simulations of pulse propagation in fibers
Actos procesales, comunicación procesal y medios electrónicos
No full textEmbargado hasta 01/01/2100El presente libro contiene un estudio de las normas que regulan los actos procesales en la Ley de Enjuiciamiento Civil y la aplicación práctica que se viene realizando de las mismas, con especial referencia a los aspectos que se han presentado como problemáticos en estos casi 20 años de vigencia y sobre los que existe jurisprudencia al respecto.
La obra tiene dos partes claramente diferenciadas. En la primera se recoge el régimen general de los actos procesales, y engloba el concepto, las clases y los requisitos de estos actos, más el análisis de la fe pública judicial y la documentación y custodia de las actuaciones, unido a los aspectos relativos a la validez y a la nulidad de los actos del proceso.
La segunda parte se dedica a la comunicación procesal en sentido amplio, es decir, tanto a la realizada desde las partes al tribunal a través de la presentación de escritos y documentos, como a los actos de comunicación del tribunal a las partes, pasando por el traslado de copias entre partes.
Y todo ello atendiendo particularmente el empleo de medios electrónicos en las actuaciones procesales, el cual se ha potenciado notablemente en nuestro proceso civil desde a reforma de 2015.
Este Tomo forma parte de una colección, formada por otros cuatro volúmenes, que contienen diversas monografías donde se exponen las principales materias del proceso civil español
Dose-dependent S-allyl cysteine ameliorates multiple sclerosis disease-related pathology by reducing oxidative stress and biomarkers of dysbiosis in experimental autoimmune encephalomyelitis
No full textEmbargado hasta 01/01/2100.Garlic is a component of the Mediterranean diet. S-allyl cysteine (SAC), the most common organosulphur present in garlic, possesses neuroprotective properties. This investigation was performed to evaluate the dose-dependent protective action of SAC on oxidative damage, inflammation and gut microbiota alterations biomarkers. Experimental autoimmune encephalomyelitis (EAE) as a model of multiple sclerosis (MS) was induced by the myelin oligodendrocyte glycoprotein (MOG), whose effects were quantified by examining the changes in: clinical score, lipid peroxidation products, carbonylated proteins, glutathione system, tumor necrosis factor alpha (TNFα), and lipopolysaccharide membrane bacteria (LPS). Our results reveal that MOG induces paralysis, oxi- dative damage and increases in LPS binding protein (LBP) and LPS levels. In this work, two doses of SAC were compared with two dose of N-acetyl cysteine (NAC). SAC was more effective than NAC and it prevented the harmful effects induced by MOG more effectively at the dose of 50 mg/kg than that of 18 mg/kg. Surprisingly, NAC increases LBP levels while SAC had not such negative effect. In conclusion the data show the ability of SAC to modify EAE evolution
Cognitive-motor interference during gait in patients with Multiple Sclerosis: a mixed methods Systematic Review
No full textEmbargado hasta 01/01/2100.Background: Cognitive-motor interference (CMI) has been proposed as a valid marker of daily life impairment in Multiple Sclerosis (MS). The heterogeneity and scarce number of studies regarding CMI in MS has hampered the synthesis of the existing evidence. The present systematic review employed a mixed methods approach with the aim of identifying and describing variables under which CMI is particularly useful to assess patients with MS.
Results: MS patients showed significant CMI. The motor variables that were most sensitive in detecting significant CMI were velocity (m/s), cadence (steps/min), and double support (% gait cycle), which was also specific for MS. Among the cognitive tasks, Alternate Alphabet and Serial Subtracting 7 s were sensitive, whereas Verbal Fluency were both sensitive and specific to CMI in MS.
Conclusions: CMI should be assessed in MS with a standardised dual task such as the Verbal Fluency task while walking, with measurements of the double support time and the effect on the cognitive task. The clinical usefulness of CMI in the assessment of patients with MS is discussed
Haloacetic Acids in Swimming Pools: Swimmer and Worker Exposure
No full textEmbargado hasta 01-01-2100For the first time, the exposure of swimmers and workers to haloacetic acids (HAAs) in indoor and outdoor pools was evaluated through the analysis of urine samples. The subjects of this study, 49 volunteers, were male and female workers as well as swimmers (adults and children) who regularly attended an indoor pool (January June) and an outdoor one (July and August). The results showed that HAAs appeared 20 30 min after exposure and were eliminated within 3 h. After 2 h exposure, urine samples taken from workers contained dichloroacetic (DCAA) and trichloroacetic (TCAA) acids at ∼300 and ∼120 ng/L levels since HAAs were aerosolized in the indoor ambient, whereas only DCAA was found in some workers’ urine samples from the outdoor pool but at∼50 ng/L levels, despite the fact that the outdoor pools generally had somewhat higher levels of HAAs than the indoor pools. After 1 h swimming TCAA, DCAA and MCAA were present at concentrations of ∼4400, ∼2300, and ∼560 ng/L, respectively, in the swimmers’ urine in the indoor pool; similar
results were obtained from the swimmers in the outdoor pool due to accidental ingestion. Finally, exposure estimates indicate that ingestion is the major route of exposure (∼94%), followed by inhalation (∼5%) and dermal contribution (∼1%)
Las imágenes de mujeres en los libros de texto de Educación Primaria
No full textEmbargado hasta 01/01/2100.Este trabajo investiga el impacto de la historia de las mujeres en los materiales educativos, con especial mención a las edades media y moderna. El objetivo principal de la investigación es analizar las imágenes de mujeres en los temas de Historia de los libros de texto de 5º de Educación Primaria de la LOMCE, de las cuatro editoriales más utilizadas en esta etapa educativa. Los resultados de la investigación confirman que las imágenes presentes en los materiales analizados siguen incidiendo en una imagen
tradicional de las mujeres, pese a que ese papel ha quedado desmentido tras años de investigación
Impact of the PROVAUR stewardship programme on linezolid resistance in a tertiary university hospital: a before-and-after interventional study
No full textEmbargado hasta 01/01/2100Background
There is little evidence of the impact of antimicrobial stewardship programmes on antimicrobial resistance.
Objectives
To study the efficacy and safety of a package of educational and interventional measures to optimize linezolid use and its impact on bacterial resistance.
Methods
A quasi-experimental study was designed and carried out before and after implementation of a stewardship programme in hospitalized patients with Gram-positive infections treated with linezolid.
Results
The intervention reduced linezolid consumption by 76%. The risk of linezolid-resistant CoNS isolates (OR = 0.37; 95% CI = 0.27–0.49; P < 0.001) and Enterococcus faecalis (OR = 0.44; 95% CI = 0.21–0.90; P = 0.03) during the intervention period was lower than in the pre-intervention period.
Conclusions
A programme to optimize linezolid use can contribute to reducing the resistance rate of CoNS and E. faecalis to this antibiotic
A feasibility study on piezoelectric energy harvesting from the operational vibration of a highway bridge
No full textEmbargado hasta 01-01-2100Vibration-based energy harvesting represents a clean power technology that can be of interest for application in civil engineering structures. This study focuses on energy harvesting using cantilever piezoelectric devices excited by operational and ambient bridge vibration. The optimal design and analysis of energy harvesters is usually performed using the mean and standard deviation of a response quantity of interest (i.e. voltage) under broadband Gaussian white noise excitation. In this paper, a holistic approach to the problem is addressed through the statistics of the voltage of piezoelectric energy harvesters under real measured bridge vibration base excitation. A new semi-analytic expression of the expected power is developed. The solution is based on the closed-form of the frequency response function between the harvester output voltage and the base excitation, and the experimentally measured spectral density of the
latter. A study on the influence of the electromechanical coupling of the problem equations is first conducted. Then, a sensitive analysis of piezoelectric energy harvester parameters is performed. The critical analysis is developed through a case study of the measured long-term vibrations of a bowstring-arch highway bridge. Both operational and ambient vibration records are considered in the feasibility study. The results show the potential of the semi-analytic expression to evaluate the harvested power of piezoelectric harvesters under operational structural vibration. This is a promising approach to confidently develop future analyses on the power requirements of wireless sensor networks for SHM
Assessment of Fatigue in Spondyloarthritis and Its Association with Disease Activity
No full textEmbargado hasta 01-01-2100Objective: To evaluate fatigue in patients with spondyloarthritis (SpA) and to define its association with disease-related factors and patients' features.
Methods: A cross-sectional multicenter study which includes 2251 patients with SpA selected from the national Spondyloarthropathies Registry (the Spanish Society of Rheumatology; REGISPONSER) Spanish cohort. The primary outcome was the assessment of fatigue performed with the first item of the Bath Ankylosing Spondyloarthritis Disease Activity Index followed by the study of its relation with different factors organized into 4 groups: sociodemographics, emotional, disease-related, and disease activity. Univariate logistic regressions, multivariate logistic regression, and multiple linear regressions were performed to relate fatigue with the studied covariates.
Results: Mean fatigue score in all patients with SpA was 4.3 ± 2.9, with statistically significant differences between different SpA types. In univariate logistic regressions, significant differences were seen for many variables included in the 4 groups. Multivariate logistic regression showed that high fatigue score was related with sex (female), emotional component, the Ankylosing Spondylitis Quality of Life score, stiffness, and high levels of 2 visual analog scale items (vertebral pain in the last week and patient's global assessment of disease activity). The multivariate linear regression showed that fatigue was mainly explained by disease-related factors and disease activity (54.1%), but sex and emotional status may also be involved in 13.5% of the variance.
Conclusion: Fatigue is associated with disease-related factors and mostly with SpA activity. However, the emotional component and sex may contribute to the onset of fatigue