Repositorio de la Asociación Española de Neuropsiquiatría
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Effect of solution focused approach on overcome vaccine rejection
No full textAmaç: Bu çalışma, çözüm odaklı yaklaşımın aşı reddinin giderilmesine etkisini belirlemek amacıyla yapıldı. Materyal ve Metot: Araştırma ön test- son test kontrol gruplu yarı deneme modeli olarak Kasım 2020 ile Mayıs 2021 tarihleri arasında uygulandı. Araştırmanın evrenini Bingöl ilinde yaşayan, 0-24 ay arasındaki bebeklerine aşı yaptırmak istemeyen 148 kadın ve erkek oluşturdu. Bireyler olasılıklı örnekleme yöntemlerinden basit rastgele örnekleme yöntemi ile örneklem grubuna seçildi, randomize olarak sıralandı. Deney grubunda toplam 43 kişi, kontrol grubunda 23 kişi ile araştırma tamamlandı. Araştırmada tanıtıcı bilgi formu ve Çocukluk Çağı Aşılarına İlişkin Ebeveyn Tutumları Ölçeği kullanıldı. Deney grubu, gruplara ayrıldı ve bir grup 8 kişi diğer gruplar 7 kişi olmak üzere toplamda 6 grup oluşturuldu. Her bir gruba, dört oturum çözüm odaklı yaklaşım danışmanlığı verildi. Her oturum yaklaşık 60-90 dk sürdü. Bulgular: Deney grubundaki ebeveynlerin çocukluk çağı aşıları hakkında ebeveyn tutumları ölçeği ön test puan ortalaması 25.76±3.08, son test puan ortalaması 16.69±3.81 bulunmuştur. Kontrol grubundaki ebeveynlerin ön test puan ortalaması 27.21±2.17, son test puan ortalaması 25.60±2.27 bulunmuştur. Yapılan analizler sonucunda iki ölçüm arasında istatiksel olarak önemli fark bulunmuştur. ÇOY uygulanmasından sonra çocukluk çağı aşıları hakkında ebeveyn tutumları ölçeği davranış alt boyutunda artış bulunurken tutum ve güvenlik alt boyutlarında önemli azalma görüldü (p<0.05). Sonuç: Çözüm Odaklı Yaklaşım Terapisi, ebeveynlerin aşıya yönelik tutum ve davranışlarını olumlu yönde değiştirmiştir. Anahtar Kelimeler: Aşı, Aşı Reddi, Çözüm Odaklı Yaklaşım, Hemşirelik.Aim: This study was carried out to determine the effect of solution focused approach on the elimination of vaccine rejection. Material and Method: The study was applied as a quasi-trial model with pretest-posttest control group between November 2020 and May 2021. The population of the study consisted of 148 couples (female-male) who did not want to have their 0-24 month old babies vaccinated in the Bingöl. Individuals were randomly selected from the probabilistic sampling methods by simple random sampling method. A total of 43 individuals in the experimental group and 23 individuals in the control group completed the study. A descriptive data form including socio-demographic information, PACV scale were used. The experimental group was divided into groups and a total of 6 groups were formed, one group being 8 people and the other group being 7 people. Four sessions of solution focused approach counseling were applied to each group. Each session lasted about 60-90 minutes. Results: The average of the pretest scores of the individuals in the experimental group 25.76 ± 3.08, and the mean posttest score 16.69 ± 3.81. The pretest mean score of the subjects in the control group 27.21 ± 2.17, and the mean posttest score 25.60 ± 2.27. As a result of the analyzes, a statistically significant difference was found between the two groups. In post-intervention individuals; a decrease in the attitude and security subscale was found, while an increase in the behavior subscale were observed (p<0.05). Conclusion: Solution Focused Approach Therapy has changed positively parents' attitudes and behaviors towards vaccination. and increased healtly lifestyle behaviors. Keywords: Vaccine, Vaccine Rejection, Solution Focused Approach, Nursing
Linking actors and scales by green grabbing in Bozbuk and Kazikli
No full textThis paper provides perspectives on the processes and consequences of large-scale ecotourism development for environmental ends in Bozbuk and Kazikli, two small forest communities on Turkey's West Southern Aegean coast. We employ a green grab framework to link various actors' operations and various scales operating in communities. To unpack these treatments, we asked two questions: 1) How do various actors negotiate green grabbing to subordinate indigenous land claims to their interests? 2) How do various scales arrange green grabbing to mediate indigenous land claims? In addition to these questions, we try to understand how green grabs are motivated by political networks, labor-capital mobilization, and environmental regulations. This model provides more specific treatments of economy and policy orientations on various scales and more detailed empirical examinations of actor orientations in resource transformations
Identification of bacterial species in milk by MALDI-TOF and assessment of some oxidant-antioxidant parameters in blood and milk from cows with different health status of the udder
No full textThis study aimed to identify bacterial pathogens in milk samples from dairy cows with sub -clinical and clinical mastitis as well as to assess the concentrations of oxidant-antioxidant param-eters [malondialdehyde (MDA), reduced glutathione (GSH), and total GSH levels] in both blood and milk samples. From a total of 200 dairy cows in 8 farms, 800 quarter milk samples obtained from each udder were tested in the laboratory for the presence of udder pathogens. Cultivated bacteria causing intramammary infection from milk samples were identified by Matrix-Assisted Laser Desorption/Ionization-Time of Flight (MALDI-TOF). In addition, from tested animals 60 cows were selected includ??ng 20 healthy cows that were CMT negative, 20 cows with subclini-cal mastitis (SM), and 20 cows with clinical mastitis (CM) for detection of MDA, GSH, and total GSH levels in blood and milk samples. Three hundred and eighty (47.5%; 380/800), 300 (37.5%; 300/800), and 120 (15%; 120/800) of milk samples, respectively were CMT positive or SM and CM, and those positives were cows from different farms. We observed that 87.4% (332/380), 25.3% (76/300), and 34.2% (41/120) of cows with CMT positive, CMT negative, and CM had bacterial growth. The most predominantly identified bacteria were Staphylococcus chromogenes (18.7%) obtained mainly from SM and Staphylococcus aureus (16.7%) as the most frequent cau-se of CM. According to our results, dairy cows with CM had the highest MDA levels, the lowest GSH, and total GSH levels in both blood and milk samples however, high MDA levels and low GSH levels in milk samples with SM were observed. Based on our results, lipid oxidant MDA and antioxidant GSH could be excellent biomarkers of cow???s milk for developing inflammation of the mammary gland. In addition, there was no link between nutrition and MDA and GSH levels.Department of Medical Microbiology, Faculty of Medicine, Inonu University, Malatya, Turkey; Slovak grant KEGA [006UVLF-4-2020.]This research was funded by Professor Baris OTLU from Department of Medical Microbiology, Faculty of Medicine, Inonu University, Malatya, Turkey and Slovak grant KEGA no. 006UVLF-4-2020
Removal of Reactive Red 120 using immobilized TiO2 in the presence of UV light
No full textRemoval of Reactive Red 120 (RR120) dye in aqueous solution was investigated using immobilized TiO2 in the presence of UV light. TiO2 was deposited onto microscope slides by heat attachment method. SEM analyses confirmed that all microscope slides were coated with TiO2 particles completely after single, two, three and four layers coating. The removal efficiency increased with repetitive coating up to three layers. The highest removal efficiency of 94% was obtained at pH 3 within 300 min of reaction time. Complete removal was observed with 5 and 10 mg dm(-3) dye concentrations whereas removal efficiency decreased from 96 to 52% when initial RR120 concentration increased 15 mg dm(-3) to 30 mg dm(-3). The results of nonlinear optimization showed that the kinetics of removal of RR120 in the range of concentration studied described by L-H kinetic expression. The experiments conducted with radical scavengers indicated that hydroxyl radicals and photogenerated hole and electrons were main reactive species in photocatalytic removal of RR120. The photonic efficiency of immobilized system was lower than that of suspended system. Minor drop (6%) in the removal of RR120 with three layers coated slide after four consecutive cycles of 300 min indicated the reusability and stability of coated slides. A possible degradation mechanism for degradation of RR120 was proposed according to detected intermediate compounds. Mineralization of RR120 was monitored by generation of NO3- and SO42- ions in solution during photocatalytic reaction
Spondyloarthritis recovering after scorpion sting: A case report
No full textScorpion venom, which is also utilized in Traditional Chinese Medicine, has been an efficient alternative medicine practice passed down from generation to generation since the Ancient Roman Period. Scorpion venom is now being investigated as a raw material (drug precursors) in a variety of sectors including new-generation pharmaceuticals. We present a 63-year-old male patient who had sacroiliitis symptoms that went away after a scorpion sting, and who recovered completely during follow-up. Apart from developing scorpion venom as a complementary therapy to existing medical techniques in the treatment of chronic inflammatory illnesses, more research into the effects of this prospective pharmaceutical on these diseases is required
Theoretical calculation of newly synthesized tetrazolopyrimidine derivatives as a potential corrosion inhibitor
No full textIn this work, we wanted to define a general and comprehensive strategy for the synthesis of tetrazolo[1,5-a]pyrimidine derivatives. For this purpose, we obtained new tetrazolo[1,5-a]pyrimidine molecules via the mercury-promoted desulfurization reaction, including hydrolysis, cyclizations, and eliminations. All of the molecules were characterized by FT-IR, H-1-NMR, C-13-NMR, and elemental analysis. On the other hand, the potentials of compounds as corrosion inhibitors were calculated at B3LYP/6-31G (d, p) level via density functional theory (DFT).VanYYU [FYL-2018-7181]This work was supported by the VanYYU, Project No: FYL-2018-7181
In-vitro activity of fosfomycin against Escherichia coli and Klebsiella pneumoniae bloodstream isolates and frequency of OXA-48, NDM, KPC, VIM, IMP types of carbapenemases in the carbapenem-resistant groups
No full textThe aim of this study was to determine the in-vitro activity of fosfomycin against Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) isolates and the frequency of OXA-48, NDM, KPC, VIM, IMP types of carbapenemases in the carbapenem-resistant (CR) groups. A total of 346 isolates (126 E. coli and 220 K. pneumoniae) from nosocomial bloodstream infections were included. Carbapenem and fosfomycin susceptibility were tested by Etest (bioMerieux, France) and agar dilution methods, respectively and evaluated in accordance with EUCAST criteria. The presence of OXA-48, NDM, KPC, VIM, IMP types of carbapenemases were conducted by using PCR method. Of the total 346 isolates, 185 (41 E. coli, 144 K. pneumoniae) were CR. Fosfomycin susceptibility of E. coli was higher than 95% and was not statistically significant between the CR and carbapenem-susceptible (CS) groups. Fosfomycin susceptibility of CS and CR K. pneumoniae was 90.7% and 69.4%, respectively, and statistically significantly lower in CR group. Of the total 185 CR isolates, 163 (32 E. coli, 131 K. pneumoniae) were producing carbapenemases. OXA-48 was the prominent carbapenemase type produced by E. coli (96.8%) and K. pneumoniae (70.9%). The frequency of NDM and KPC types produced by K. pneumoniae was 20.6% and 15.2%, respectively. Fosfomycin has substantial in-vitro activity against nosocomial CS and CR E. coli and CS K. pneumoniae bloodstream isolates. However, due to the risk of emerging resistance with fosfomycin monotherapy, combination therapy should be considered to obtain the possible additive or synergistic activity. Emerging fosfomycin resistance of CR K. pneumoniae isolates is alarming and OXA-48 is still the prominent carbapenemase type in Turkey
Evaluation of serum TWEAK, TRAIL, and oxidative stress markers in rosacea patients
No full textBackground Rosacea is a chronic inflammatory skin disease of unknown pathogenesis. TWEAK and TRAIL are two cytokines thought to have a role in the pathogenesis of some inflammatory and autoimmune diseases. Aims The purpose of this study was to examine TWEAK and TRAIL serum levels and oxidative stress markers in patients with rosacea. Material and Method Forty rosacea patients and 40 sex- and age-matched healthy controls were involved in the study. Serum TWEAK and TRAIL levels were evaluated with ELISA kits. Serum total antioxidant status, total oxidant status, total thiol, native thiol, disulfide levels were evaluated, and oxidative stress index was computed. Results Serum levels of TWEAK, TRAIL, and oxidative stress markers did not differ statistically in the patients and controls. Both TWEAK and TRAIL levels in the patients were detected to be statistically higher in male than in female. Conclusion TWEAK and TRAIL may not have a systemic effect in rosacea, unlike other inflammatory diseases. More studies are needed to investigate the role of TWEAK and TRAIL in rosacea.Scientific Research Projects Coordination Unit of Inonu University [TTU-2021-2421]The study was supported by the Scientific Research Projects Coordination Unit of Inonu University with the project code TTU-2021-2421
Marked social networks: A new model of social networks based on dynamic behaviors
No full textSocial networks are electronically information sharing systems, due to this case, there are many studies on social networks. When studying social networks, text-based solution methods can be used; this type of study is outside the scope of this paper. Some studies have used mathematical models such as graphs, and graphs are mathematical models to represent many things, and social networks are one of them. However, graphs are static models whose structure cannot match the behaviors of social networks. To get rid of this case, Petri nets have been used in some recent studies , however, they have some deficien-cies (obtained models are not complete and sound). Because of this case, we modeled social networks by using Petri nets. The resulting model is called Marked Social Network. The marked social network has two types such as Concurrent Marked Social Network and Parallel Marked Social Network. The obtained mod-els were analyzed in case of behavioral and structural properties, and the major properties of the model were determined. All these properties are described in this study.(c) 2021 Karabuk University. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Effectiveness of oral prednisone or corticosteroid injection therapy administered into the glenohumeral joint with ultrasonography in patients with adhesive capsulitis and evaluation in terms of axillary (inferior) pouch thickness
No full textAmaç: Adheziv kapsülit (AK)'li hastalarda oral prednizon veya ultrasonografi eşliğinde glenohumeral eklem içine uygulanan kortikosteroid tedavisinin etkinliği ve aksiller(inferior)poş kalınlıkları bakımından değerlendirilmesi. Gereç ve Yöntem: Çalışmamıza 18-65 yaş aralığında omuz eklem hareket kısıtlığı ve ağrılı klinik ön tanısı AK olan 48 hasta dâhil edildi. Bireyler randomize olarak enjeksiyonve oral grupolmak üzere ikiye ayrıldı. Tüm bireylerin demografik bilgileri alındıktan sonra randomizasyon şeması ile belirlenen birinci grubaUSG eşliğinde glenohumeral enjeksiyon ile 3 ml %2 prilokain ve 1 ml 20 mg triamsonolon hekzasetenoid karışımı, diğer grubaoral prednizon0.5 mg/kg dozdan başlanıp 5'er gün 4 mg'lık dozlarda azaltıldı. Her iki gruba da aynı zamanda fizik tedavi başlandı. 3 haftalık egzersizuygulaması sonrası hastalar ev egzersizleri ile devam etti. Çalışmaya başlandığı gün ve 6.haftada SPADI anketi, gonyometrik aktif ve pasif EHA ölçümleri ve ultrasongrafik değerlendirme ile aksillerpoş kalınlık ölçümleri (AR)yapıldı. Bulgular: Çalışmanın steroid enjeksiyonu grubuna yaş ortalaması 55.16±6.39 yılolan 24 hasta ile oral prednizon grubuna ise yaş ortalaması 55.37±8.1yıl olan 24 hasta dâhil edilmiştir.Çalışmamıza katılan her iki grup hastada tedavi öncesi ve sonrası pasif-aktifolarak belirlenen fleksiyon, abdüksiyon, ekstansiyon, internal ve eksternal rotasyon ortalama değerleri arasında istatistiksel olarak anlamlı fark tespit edildi (p0.05). Sonuç: Bu verilere dayanarak, AK hastalarında steroid enjeksiyonu+FTR grubunda daha belirgin olmak üzere her iki grupta omuz ağrı anketinde azalma ve pasif-aktif eklem hareket açıklığında fleksiyon ve abduksiyonda bariz olarak artış olmuştur. Tedavi sonrası her iki grupta da USG ile aksiler poş kalınlığı değerleri azalmasına rağmen birbirine kıyaslandığında farklılık yoktu. Adheziv Kapsülit tanı ve tedavisinde ultrasonografinin bir kriter olacağı umuduyla daha büyük gruplarla yeni çalışmalara ihtiyaç vardır.Objective: The aim of this study was to evaluate the efficacy of oral prednisone or corticosteroid therapy administered into the glenohumeral joint with ultrasonography in patients with adhesive capsulitis and its evaluation in terms of axillary (inferior) pouch thicknesses. Methods:Our study included 48 patients aged 18-65 years with shoulder joint range of motion and painful clinical prediagnosis of AK. Individuals were randomly divided into injection and oral groups.After obtaining the demographic information of all individuals, the first group determined by the randomization scheme was administered glenohumeral injection with 3 ml of 2% prilocaine and 1 ml of 20 mg triamsonolone hexacetenoid mixture under the guidance of USG, and oral prednisone 0.5 mg/kg was administered to the other group in doses of 4 mg for 5 days. reduced. Physical therapy was started in both groups at the same time. After 3 weeks of exercise, the patients continued with home exercises. SPADI questionnaire, goniometric active and passive ROM measurements, ultrasonographic evaluation and axillary pouch thickness measurements (AR) were performed on the day of the study and at the 6th week. Results: The study included 24 patients with a mean age of 55.16±6.39 years in the steroid injection group and 24 patients with a mean age of 55.37±8.1 years in the oral prednisone group. A statistically significant difference was found between the mean values of flexion, abduction, extension, internal and external rotation determined as passive-active before and after the treatment in both groups of patients who participated in our study (p0.05). Conclusion:Based on these data, there was a decrease in shoulder pain questionnaire and a significant increase in passive-active range of motion, flexion and abduction in both groups, more significantly in the steroid injection+FTR group in AK patients. Although the axillary pouch thickness values decreased in both groups after the treatment, there was no difference when compared to each other. There is a need for new studies with larger groups in the hope that ultrasonography will be a criterion in the diagnosis and treatment of Adhesive Capsulitis