Repositorio de la Asociación Española de Neuropsiquiatría
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POLLEN AND FUNGAL SPORE COMPOSITION VARIATIONS OF HONEYS ACCORDING TO DIFFERENT FEEDING METHODS
No full textHoney samples were collected from two districts of Malatya (Eastern Turkey) Battalgazi and Dogansehir for melissopalynological analysis after the honey season in 2018. The survey was conducted to 3 different feeding groups, Glucose, Sucrose, Bee Feed and a Control group in each study area. The samples were prepared according to Louveaux et al., (1978) procedure. Melissopalynological examinations were done to determine both pollen grains and fungal spores for each feeding group and districts. According to the microscopic analyses the dominant pollen types were determined as Astragalus, Cistus, Poaceae, Verbascum, Echium, Berberis, Artemisia, Plantago, Vicia, Onobrychis, Cichorioideae, Astragalus pollen grains were most frequent in glucose and control groups, Cistus pollen grains were widely represented in sucrose and bee feed groups in both study area. Dominant fungal spore types were determined as Aspergillus / Penicillium, Urediniospores, Cladosporium and Myrotechium. Aspergillus / Penicillium spores were dominated almost all samples by varying degrees. Analysis of pollen grains and fungal spores is useful instrument for determining the botanical, geographical and ecological sources of honey. This paper could be guide to beekeepers for selecting convenient apiary domains and appropriate feeding methods for qualitative honeys and the study is also help agriculturists for increasing the crop yield, the bees could be diverting to less-preferred plants during forages by sugar manipulation in order to cultivation improving.Inonu University Scientific Research Project Unit [FCD-2018-1118]This study was funded by Inonu University Scientific Research Project Unit (FCD-2018-1118)
Optimal architecture artificial neural network model design with exploitative alpha gray wolf optimization for soft calibration of CO concentration measurements in electronic nose applications
No full textThe low-cost and small size solid-state sensor arrays are suitable to implement a wide-area electronic nose (e-nose) for real-time air quality monitoring. However, accuracy of these low-cost sensors is not adequate for precise measurements of pollutant concentrations. Artificial neural network (ANN) estimation models are used for the soft calibration of low-cost sensor array measurements and significantly improve the accuracy of low-cost multi-sensor measurements. However, optimality of neural architecture affects the performance of ANN estimation models, and optimization of the ANN architecture for a training data set is essential to improve data-driven modeling performance of ANNs to reach optimal neural complexity and improved generalization. In this study, an optimal architecture ANN estimator design scheme is suggested to improve the estimation performance of ANN models for e-nose applications. To this end, a gray wolf optimization (GWO) algorithm is modified, and an exploitative alpha gray wolf optimization (EA-GWO) algorithm is suggested. This modification enhances local exploitation skill of the best alpha gray wolf search agent, and thus allows the fine-tuning of ANN architectures by minimizing a multi-objective cost function that implements mean error search policy. Experimental study demonstrates the effectiveness of optimal architecture ANN models to estimate CO concentration from the low-cost multi-sensor data
Feelings, Difficulties and Attitudes in relation to Fasting: A Qualitative Study on Spiritual Coping Among Turkish Patients with Type 2 Diabetes
No full textThis study aims to reveal the feelings, difficulties, attitudes, and spiritual coping status of Turkish patients with Type 2 diabetes mellitus toward fasting during Ramadan. The sample of this descriptive qualitative study consists of 14 patients diagnosed with Type 2 diabetes. We determined two main themes and relevant sub-themes. The first was the feelings and difficulties experienced due to diabetes mellitus with the sub-themes of negative emotions and difficulties in fasting. The second theme was identified as religious and spiritual coping with the sub-themes of believing the disease comes from God, having difficulty in adhering to disease-specific practices while fasting, and feeling that fasting facilitates coping and provides relief. In conclusion, it was determined that the patients continued to fast despite the difficulties and that fasting facilitated coping and provided relaxation
The knowledge level and awareness of family physicians about developmental hip dysplasia
No full textAmaç: Bu çalışmanın amacı aile hekimlerinin gelişimsel kalça displazisi hakkındaki bilgi düzeyini ve farkındalığını araştırmaktır. Materyal ve Metot: Gelişimsel kalça displazisi ile ilgili, Sağlık Bakanlığı Kılavuzu ve uluslararası literatürden yararlanarak "Aile Hekimlerinin Gelişimsel Kalça Displazisi Hakkındaki Bilgi Düzeyi ve Farkındalığının Değerlendirilmesi Anket Formu" oluşturulmuştur. Oluşturulan anket 32 kişiye uygulanmış, anlaşılmayan yerler düzeltilmiş ve Google Anket uygulama yöntemi üzerinden gönüllülük esasına göre aile hekimlerine uygulanmıştır. Anketin birinci bölümü, katılımcıların sosyo-demografik ve diğer verilerinin elde edildiği Katılımcı Bilgi Formu olup, 13 sorudan oluşmaktadır. Anketin ikinci bölümü ise; 2 tanesi beşli, 1 tanesi altılı Likert tipi olmak üzere 17 sorudan oluşmaktadır. Sonuç olarak 241 değerlendirme formu istatistiksel analize tabii tutulmuştur. Bulgular: Çalışmaya katılan 241 hekimin 85'i (%35.3) kadın ve 156'sı (%64.7) erkek ti. Hekimlerin 150'si (%62.2) pratisyen aile hekimi, 36'sı (%14.9) Aile hekimliği uzmanı ve 55'i (%22.8) Sözleşmeli Aile Hekimliği Uzmanlık Eğitimi (SAHU) asistanıydı. Hekimlerin GKD bilgi ve farkındalık test skoru 35.5±6.9'du. 241 aile hekiminin çalıştığı birimde son 3 ayda GKD taraması yapılan bebek sayısı 2385'ti. Aile hekimliği uzmanı ve SAHU asistanı olmak (p=0.004), hekimin GKD tanısı almış bebek hastasının olmaması (p=0.007), GKD bilgi düzeyini orta ve yeterli görüyor olmak (p<0.001), GKD tarama amaçlı provakatif olmayan testleri her zaman ve genellikle yapıyor olmak (p=0.001), GKD tarama amaçlı provakatif olan testleri genellikle yapıyor olmak (p=0.003), uzmanlık eğitimi almak (p=0.016), Sağlık Bakanlığı Rehberi'ni kullanmak (p=0.017), kongre, kurs ve sempozyumlara katılmak (p=0.028), bilgi ve eğitim kaynağı olarak kitap ve yayınlar (p<0.001), konu ile ilgili uzman hekimlerin bilgi ve tecrübeleri (p<0.001), ve internet, Tv, sosyal ve diğer medya'nın bulunması (p<0.001) ile GKD ile ilgili bilgi ve farkındalık test skoru arasında istatistiksel olarak anlamlı fark saptandı. Sonuç: Aile hekimlerinin GKD ile ilgili mevcut bilgi düzeyi ve farkındalığının arttırılması ve güncellenmesi ile GKD'nin önlenmesi, tanı ve tedavisindeki başarı oranlarını artıracaktır. Anahtar Kelimeler: Aile hekimliği, gelişimsel kalça displazisi, tarama, yenidoğanAim: The aim of this study is to investigate the level of knowledge and awareness of family physicians about developmental dysplasia of the hip. Material and Method: The "Assessment of Knowledge level and Awareness of Family Physicians about Developmental Hip Dysplasia Questionnaire Form" was created by using the Ministry of Health Guide and international literature on developmental hip dysplasia. The created questionnaire was applied to 32 people, the incomprehensible parts were corrected and it was applied to family physicians on a voluntary basis through the Google Questionnaire application method. The first part of the questionnaire is the Participant Information Form, in which the socio-demographic and other data of the participants are obtained, and consists of 13 questions. The second part of the survey is; It consists of 17 questions, 2 of which are five-point and one is six-point Likert type. As a result, 241 evaluation forms were subjected to statistical analysis. Results: Of the 241 physicians participating in the study, 85 (35.3%) were female and 156 (64.7%) were male. 150 (62.2%) of the physicians were general practitioners, 36 (14.9%) family medicine specialists, and 55 (22.8%) Contracted Family Medicine Specialization Training (CFMST) residents. The physicians' DDH knowledge and awareness test score was 35.5±6.9. In the unit where 241 family physicians work, the number of babies who underwent DDH screening in the last 3 months was 2385. A statistically significant difference was found between the status being a family medicine specialist and SAHU assistant (p=0.004), the physician's absence of a baby patient diagnosed with DDH (p=0.007), seeing the level of knowledge of DDH as medium and sufficient (p<0.001), always and usually performing non-provocative tests for DDH screening (p=0.001), usually performing provocative tests for DDH screening (p=0.003), to receive specialist training (p=0.016), to use the Ministry of Health Guide (p=0.017), to attend congresses, courses and symposiums (p=0.028), availability of books and publications (p<0.001), knowledge and experience of specialist physicians on the subject (p<0.001) and internet, TV, social and other media (p<0.001) as information and educational resources and the knowledge level and awareness test score about DDH. Conclusion: Increasing and updating the current level of knowledge and awareness of family physicians about DDH will increase the success rates in prevention, diagnosis and treatment of DDH. Key Words: Family medicine, developmental hip dysplasia, screening, newbor
Thromboembolism in Children
No full textObjectiveTo study pediatric patients who were diagnosed with thrombosis between January 2009 and March 2020.MethodsPatients were evaluated with respect to thrombophilic risk factors, localization of the thrombus, response to treatment, and recurrence rates during the last 11 y.ResultsAmong 84 patients, 59 (70%) had venous thrombosis and 20 (24%) had arterial thrombosis. The number of documented thrombosis amongst hospitalized children in authors' hospital has increased over the years. It has been observed that the annual incidence of thromboembolism has increased after 2014. Thirteen patients were recorded between 2009 and 2014 and 71 patients between 2015 and 2020 (until March 2020). Exact thrombosis localization could not be detected in 5 patients. The median age of patients was 8 +/- 5.95 (range 0-18). Fourteen children (16.9%) had a history of familial thrombosis. Genetic and/or acquired risk factors were detected in 81 (96.4%) of the patients. Overall, 64 patients (76.1%) had acquired risk factors such as infection (20.2%), catheterization (13.1%), liver disease (11.9%), mastoiditis (8.3%), liver transplantation (6%), hypoxic-ischemic encephalopathy (4.8%), dehydration (3.6%), trauma (3.6%) and cancer (2.4%). As genetic risk factors, the most common genetic mutations were PAI-1 4G>5G, MTHFR C677T, and MTHFR A1298C mutations. Twenty-eight (41.2%) patients had at least one genetic thrombophilic mutation. At least one homozygous mutation in 37 patients (44%) and at least one heterozygous mutation in 55 patients (65.4%) were detected.ConclusionsThe annual incidence of thrombosis has increased over the years. Genetic predisposition and acquired risk factors play an important role in etiology, treatment, and follow-up in children with thromboembolism. Especially, genetic predisposition is common. Thrombophilic risk factors should be investigated and optimal therapeutic and prophylactic measures should be promptly taken in children with thrombosis
The minstrelsy tradition and a revival leader: Ozan Rehberî in the context of Alevi revival
No full textSözlü kültür geleneğinin başlıca unsurlarından âşıklık geleneğini Alevi Uyanışı bağlamında inceleyen bu çalışma, âşıklık geleneği temsilcilerinden ve Alevi Uyanış önderlerinden Ozan Rehberî'nin yaşamı, sanatı ve eserlerinin derlenerek literatüre kazandırılması amacıyla hazırlanmıştır. Nitel bir araştırma olan bu çalışmada alan araştırması, etnografik araştırma, fenomenolojik araştırma ve durum çalışması yöntemleri model alınmıştır. Çalışmada öncelikle literatür taraması yöntemiyle edinilen bilgiler doğrultusunda kavramsal-kuramsal çerçeve oluşturulmuştur. Ardından nitel araştırmanın alan araştırması yöntemi ve bu yönteme ait görüşme tekniği ile birlikte veri toplama yöntemlerinden doküman analizi ve betimsel analiz yöntemlerinden yararlanılmıştır. Bu bağlamda alan araştırmalarından edinilen bilgilerin içerik analizi yapılarak İslamiyet tarihinde Aleviliğin ortaya çıkışından Alevi Uyanışına kadar uzanan süreç hakkında etnografik açıdan geniş kapsamlı bir görünüm sunulmuştur. Sonrasında geleneksel Türk halk müziğinin usta isimlerinden Arif Sağ, Musa Eroğlu, Yavuz Top ve Muharrem Temiz ile etik yaklaşım çerçevesinde görüşmeler gerçekleştirilerek Alevi Uyanışı olgusu fenomenolojik açıdan incelenmiş, âşıklık geleneğinin Alevi Uyanışı üzerinde nasıl bir etkisi olduğu açıklığa kavuşturulmaya çalışılmıştır. Tezin ana eksenini oluşturan Ozan Rehberî hakkında bilgi edinebilmek için ailesinden ve yakın çevresinden beş kişi ile etik yaklaşım çerçevesinde görüşmeler gerçekleştirilmiştir. Ozan Rehberî hakkında ulaşılan yazılı, görsel, işitsel, elektronik tüm belgeler doküman analizi yöntemiyle tasnif edilmiş, incelenmiş ve yorumlanmıştır. Bu bağlamda tüm yönleriyle geniş kapsamlı bir şekilde incelenen Ozan Rehberî'nin âşıklık geleneği ve Alevi Uyanışı içerisindeki konumu hakkında çeşitli değerlendirmelerde bulunulmuştur. Âşıklık geleneğini ve Alevi Uyanışını farklı bir perspektifle değerlendiren ve özgün nitelikli bir araştırma olduğu öngörülen bu çalışmanın, herhangi bir akademik çalışmada yer almamış önemli bir âşıklık geleneği temsilcisini ve eserlerini literatüre kazandırması bakımından önemli olacağı öngörülmektedir. Anahtar Kelimeler: Geleneksel Türk Halk Müziği, Âşıklık Geleneği, Alevi Uyanışı, Uyanış Önderi, Ozan Rehberî.This research paper examines the minstrel tradition, a prominent aspect of the oral cultural tradition, within the context of the Alevi Revival. Its purpose is to compile the life, art, and works of Ozan Rehberî, a representative of the minstrel tradition and a leader of the Alevi Revival movement. In this qualitative research, field research, ethnographic research, phenomenological research and case study methods were taken as models. In the study, first of all, a conceptual-theoretical framework was created in line with the information obtained through the literature review method. Subsequently, the field research method, one of the qualitative research methods, along with the interview technique associated with this approach, was employed, accompanied by data collection methods such as document analysis and descriptive analysis. In this context, a comprehensive analysis of the ethnographic progression from the emergence of Alevism to the Alevi Revival in the history of Islam was presented by analyzing the content of the information obtained through field studies. Furthermore, interviews were conducted with Arif Sağ, Musa Eroğlu, Yavuz Top, and Muharrem Temiz, renowned masters of traditional Turkish folk music, within an ethical framework, to explore the Alevi Revival phenomenologically and elucidate the influence of the minstrel tradition on the Alevi Revival. In order to gather information about Ozan Rehberi, who forms the central axis of this thesis, interviews were conducted with five individuals from his family and close circle, adhering to ethical considerations. All written, visual, audio, and electronic documents pertaining to Ozan Rehberî were classified, examined, and interpreted using the document analysis method. Within this context, comprehensive evaluations were made regarding Ozan Rehberi's minstrel tradition and his position within the extensively studied Alevi Revival. This study is anticipated to contribute as an original research endeavor that offers a unique perspective on the minstrel tradition and the Alevi Revival. It is expected to be of significance in terms of introducing an important representative of the minstrel tradition and his works to the academic literature, as they have not been adequately addressed in previous scholarly investigations. Keywords: Traditional Turkish Folk Music, Minstrel Tradition, Alevi Revival, Revival Leader, Ozan Rehberî
Outcome of split liver transplantation vs living donor liver transplantation: A systematic review and meta-analysis
No full textBACKGROUNDThe outcomes of liver transplantation (LT) from different grafts have been studied individually and in combination, but the reports were conflicting with some researchers finding no difference in both short-term and long-term outcomes between the deceased donor split LT (DD-SLT) and living donor LT (LDLT).AIMTo compare the outcomes of DD-SLT and LDLT we performed this systematic review and meta-analysis.METHODSThis systematic review was performed in compliance with the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. The following databases were searched for articles comparing outcomes of DD-SLT and LDLT: PubMed; Google Scholar; Embase; Cochrane Central Register of Controlled Trials; the Cochrane Database of Systematic Reviews; and Reference Citation Analysis (https://www.referencecitationanalysis.com/). The search terms used were: liver transplantation; liver transplant; split liver transplant; living donor liver transplant; partial liver transplant; partial liver graft; ex vivo splitting; and in vivo splitting.RESULTSTen studies were included for the data synthesis and meta-analysis. There were a total of 4836 patients. The overall survival rate at 1 year, 3 years and 5 years was superior in patients that received LDLT compared to DD-SLT. At 1 year, the hazard ratios was 1.44 (95% confidence interval: 1.16-1.78; P = 0.001). The graft survival rate at 3 years and 5 years was superior in the LDLT group (3 year hazard ratio: 1.28; 95% confidence interval: 1.01-1.63; P = 0.04).CONCLUSIONThis meta-analysis showed that LDLT has better graft survival and overall survival when compared to DD-SLT
PP-17 A case of Meckel-Gruber syndrome diagnosed in the first trimester
No full textObjective Meckel-Gruber syndrome (MGS), an autosomal recessively inherited hereditary syndrome from the group of ciliopathies, is characterized by occipital encephalocele, large polycystic kidneys and postaxial polydactyly, resulting from the involvement of multiple genes and therefore has 15 phenotypes, occurring in 1 in 13,250-140,000 live births worldwide. Prenatal ultrasonography is the best available method to diagnose MGS. In this report, we aimed to present the prenatal diagnosis of a first trimester MGS case. Case A 25-year-old patient with gravida 3, parity 1, 14 weeks and 1 day gestation according to the last menstrual period was admitted to the prenatal diagnosis and treatment unit of our clinic for a first trimester screening test. In the ultrasonographic examination of the patient who had a history of MGS in her previous pregnancy, fetal cranial evaluation revealed acrania, exencephaly, anencephaly sequence (figure 1) and open spina bifida anomaly. Fetal abdominal evaluation revealed bilateral cystic kidneys (figure 2). Fetal extremity evaluation revealed no clear evaluation for postaxial polydactyly. The family was informed in detail about the possible poor fetal/neonatal prognosis of the fetus, which was primarily diagnosed as MGS according to the sonographic findings, and invasive prenatal diagnostic testing and pregnancy termination were presented as options. The family decided to terminate the pregnancy without invasive prenatal diagnostic testing. After termination of pregnancy, genetic examination of the abortion material was requested. Macroscopic examination of the abortion material confirmed prenatal findings (figure 3). The family was referred to the genetics outpatient clinic. Discussion Prenatal features of MKS, such as postaxial polydactyly, encephalocele, and polycystic kidneys, are often profound and easily detectable in the first trimester. The findings of a large population-based review that estimated the incidence of typical symptoms were as follows: encephalocele, 83.8%; polydactyly, 87.3%; and cystic kidney disease, 97.7%.[2] Therefore, targeted prenatal diagnosis of MKS is usually triggered by these findings. However, the presence of encephalocele is not specific to MKS. Only 21% of fetuses diagnosed with prenatal encephalocele will have MCS,[3] and the same is true for polycystic kidney finding. The majority of confirmed hereditary cystic kidney disease detected prenatally is autosomal recessive polycystic kidney disease (ARPKD), diagnosed in 81% of cases. Meckel-Gruber syndrome was found in only 8% of such cases.[5] Conclusion MGS is a rare autosomal recessive condition with a mortality of 100%; diagnosis is possible antenatally even in the first trimester of pregnancy by prenatal sonographic examination. Given its mortality, early diagnosis of MGS and other such lethal anomalies has a significant impact on family counseling, especially when it comes to termination of pregnancy. Early prenatal diagnosis and genetic counseling are important in the management of this case with a first trimester prenatal diagnosis due to the high recurrence rate of 25% in subsequent pregnancies of the mother
Investigation of the Protective Effect of Nerolidol on Dehydroepiandrosterone-induced Polycystic Ovary Syndrome in Female Rats
No full text[Abstract Not Available]Inonu University Scientific Research Projects Coordination Unit [TCD-2020/2090]This study was supported by Inonu University Scientific Research Projects Coordination Unit (Project Number: TCD-2020/2090)
Prediction of Postcoronary Artery Bypass Grafting Atrial Fibrillation: POAFRiskScore Tool
No full textBackground Atrial fibrillation (AF), a condition that might occur after a heart bypass procedure, has caused differing estimates of its occurrence and risk. The current study analyses the possible risk factors of post-coronary artery bypass grafting (post-CABG) AF (postoperative AF [POAF]) and presents a software for preoperative POAF risk prediction. Methods This retrospective research was performed on 1,667 patients who underwent CABG surgery using the hospital database. The associations between the variables of the patients and AF risk factors after CABG were examined using multivariable logistic regression (LR) after preprocessing the relevant data. The tool was designed to predict POAF risk using Shiny, an R package, to develop a web-based software. Results The overall proportion of post-CABG AF was 12.2%. According to the results of univariate tests, in terms of age ( p < 0.001), blood urea nitrogen ( p = 0.005), platelet ( p < 0.001), triglyceride ( p = 0.0026), presence of chronic obstructive pulmonary disease (COPD; p = 0.01), and presence of preoperative carotid artery stenosis (PCAS; p < 0.001), there were statistically significant differences between the POAF and non-POAF groups. Multivariable LR analysis disclosed the independent risk factors associated with POAF: PCAS (odds ratio [OR] = 2.360; p = 0.028), COPD (OR = 2.243; p = 0.015), body mass index (OR = 1.090; p = 0.006), age (OR = 1.054, p < 0.001), and platelet (OR = 0.994, p < 0.001). Conclusion The experimental findings from the current research demonstrate that the suggested tool ( POAFRiskScore v.1.0 ) can help clinicians predict POAF risk development in the preoperative period after validated on large sample(s) that can represent the related population(s). Simultaneously, since the updated versions of the proposed tool will be released periodically based on the increases in data dimensions with continuously added new samples and related factors, more robust predictions may be obtained in the subsequent stages of the current study in statistical and clinical terms.Inonu University Scientific Research Projects Coordination Unit [TCD2017-761, 761]Y This study is a part of the research project numbered TCD2017-761 (ID: 761) supported by the Inonu University Scientific Research Projects Coordination Unit