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RR Lyrae-based Distances for 39 Nearby Dwarf Galaxies Calibrated to Gaia eDR3
We provide uniform RR Lyrae-based distances to 39 dwarf galaxies in and around the Local Group. We determine distances based on a Bayesian hierarchical model that uses periods and magnitudes of published RR Lyrae in dwarf galaxies and is anchored to well-studied Milky Way (MW) RR Lyrae with spectroscopic metallicities and Gaia eDR3 parallaxes. Gaia eDR3 parallaxes for the anchor sample are a factor of 2, on average, more precise than DR2 parallaxes, and allow for a much better constrained period–luminosity–metallicity relation. While ∼75% of our distances are within 1σ of recent RR Lyrae distances in the literature, our distances are also ∼2–3 times more precise than distances in the literature, on average. On average, our distances are ∼0.05 mag closer than distances in the literature, as well as ∼0.06 mag closer than distances derived using a theoretical period–luminosity–metallicity relation. These discrepancies are largely due to our eDR3 parallax anchor. We show that the Hipparcos-anchored RR Lyrae distance scale of Carretta et al. overpredicts distances to MW RR Lyrae by ∼0.05 mag. The largest uncertainties in our distances are (i) the lack of direct metallicity measurements for RR Lyrae and (ii) the heterogeneity of published RR Lyrae photometry. We provide simple formulae to place new dwarf galaxies with RR Lyrae on a common distance scale with this work. We provide a public code that can easily incorporate additional galaxies and data from future surveys, providing a versatile framework for the cartography of the local universe with RR Lyrae
Processing methodology for the ITS_LIVE Sentinel-1 ice velocity products
The NASA MEaSUREs Inter-mission Time Series of Land Ice Velocity and Elevation (ITS_LIVE) project seeks to accelerate understanding of critical glaciers and ice sheet processes by providing researchers with global, low-latency, comprehensive and state of the art records of surface velocities and elevations as observed from space. Here we describe the image-pair ice velocity product and processing methodology for ESA Sentinel-1 radar data. We demonstrate improvements to the core processing algorithm for dense offset tracking, “autoRIFT”, that provide finer resolution (120 m instead of the previous 240 m used for version 1) and higher accuracy (20 % to 50 % improvement) data products with significantly enhanced computational efficiency (>2 orders of magnitude) when compared to earlier versions and the state of the art “dense ampcor” routine in the JPL ISCE software. In particular, the disparity filter is upgraded for handling finer grid resolution with overlapping search chip sizes, and the oversampling ratio in the subpixel cross-correlation estimation is adaptively determined for Sentinel-1 data by matching the precision of the measured displacement based on the search chip size used. A novel calibration is applied to the data to correct for Sentinel-1A/B subswath and full-swath dependent geolocation biases caused by systematic issues with the instruments. Sentinel-1 C-band images are affected by variations in the total electron content of the ionosphere that results in large velocity errors in the azimuth (along-track) direction. To reduce these effects, slant range (line of sight or LOS) velocities are used and accompanied by LOS parameters that support map coordinate (x/y) velocity inversion from ascending and descending slant range offset measurements, as derived from two image pairs. After the proposed correction of ionosphere errors, the uncertainties in velocities are reduced by 9 %–61 %. We further validate the ITS_LIVE Version 2 Sentinel-1 image-pair products, with 6-year time series composed of thousands of epochs, over three typical test sites covering the globe: the Jakobshavn Isbræ Glacier of Greenland, Pine Island Glacier of the Antarctic, and Malaspina Glacier of Alaska. By comparing with other similar products (PROMICE, FAU, and MEaSUREs Annual Antarctic Ice Velocity Map products), as well as other ITS_LIVE version 2 products from Landsat-8 and Sentinel-2 data, we find an overall variation between products around 100 m yr⁻¹ over fast-flowing glacier outlets, where both mean velocity and variation are on the order of km yr⁻¹, and increases up to 300–500 m yr⁻¹ (3 %–6 %) for the fastest Jakobshavn Isbræ Glacier. The velocity magnitude uncertainty of the ITS_LIVE Sentinel-1 products is calculated to be uniformly distributed around 60 m yr⁻¹ for the three test regions investigated. The described product and methods comprise the MEaSUREs ITS_LIVE Sentinel-1 Image-Pair Glacier and Ice Sheet Surface Velocities: version 2 (DOI: https://doi.org/10.5067/0506KQLS6512, Lei et al., 2022)
Catalytic transfer hydrogenation of N₂ to NH₃ via a photoredox catalysis strategy
Inspired by momentum in applications of reductive photoredox catalysis to organic synthesis, photodriven transfer hydrogenations toward deep (>2 e⁻) reductions of small molecules are attractive compared to using harsh chemical reagents. Noteworthy in this context is the nitrogen reduction reaction (N₂RR), where a synthetic photocatalyst system had yet to be developed. Noting that a reduced Hantzsch ester (HEH₂) and related organic structures can behave as 2 e⁻/2 H⁺ photoreductants, we show here that, when partnered with a suitable catalyst (Mo) under blue light irradiation, HEH₂ facilitates delivery of successive H₂ equivalents for the 6 e⁻/6 H⁺ catalytic reduction of N₂ to NH₃; this catalysis is enhanced by addition of a photoredox catalyst (Ir). Reductions of additional substrates (nitrate and acetylene) are also described
Directly Tracing Cool Filamentary Accretion over >100 kpc into the Interstellar Medium of a Quasar Host at z = 1
We report the discovery of giant (50−100 kpc) [O ɪɪ] emitting nebulae with MUSE in the field of TXS 0206−048, a luminous quasar at z = 1.13. “Down-the-barrel” UV spectra of the quasar show absorption at velocities coincident with those of the extended nebulae, enabling new insights into inflows and outflows around the quasar host. One nebula exhibits a filamentary morphology extending over 120 kpc from the halo toward the quasar and intersecting with another nebula surrounding the quasar host with a radius of 50 kpc. This is the longest cool filament observed to date and arises at higher redshift and in a less massive system than those in cool-core clusters. The filamentary nebula has line-of-sight velocities >300 km s⁻¹ from nearby galaxies but matches that of the nebula surrounding the quasar host where they intersect, consistent with accretion of cool intergalactic or circumgalactic medium or cooling hot halo gas. The kinematics of the nebulae surrounding the quasar host are unusual and complex, with redshifted and blueshifted spiral-like structures. The emission velocities at 5−10 kpc from the quasar match those of inflowing absorbing gas observed in UV spectra of the quasar. Together, the extended nebulae and associated redshifted absorption represent a compelling case of cool, filamentary gas accretion from halo scales into the extended interstellar medium and toward the nucleus of a massive quasar host. The inflow rate implied by the combined emission and absorption constraints is well below levels required to sustain the quasar’s radiative luminosity, suggesting anisotropic or variable accretion
In vivo hypermutation and continuous evolution
Directed evolution has revolutionized biomolecular engineering by applying cycles of mutation, amplification and selection to genes of interest (GOIs). However, classical directed evolution methods that rely on manually staged evolutionary cycles constrain the scale and depth of the evolutionary search that is possible. We describe genetic systems that achieve cycles of rapid mutation, amplification and selection fully inside living cells, enabling the continuous evolution of GOIs as cells grow. These systems advance the scale, evolutionary search depth, ease and overall power of directed evolution and access important new areas of protein evolution and engineering
Measuring Optical Extinction toward Young Stellar Objects Using Diffuse Interstellar Bands
Line-of-sight extinction estimates of well-studied young T Tauri and Herbig Ae/Be stars are based on many different measurements and analysis methods. This has resulted in wide scatter among the published A_V values for the same star. In this work, we discuss the challenges in measuring extinction to actively accreting and especially outbursting young stellar objects (YSOs). We then explore a method not previously applied to young stars utilizing diffuse interstellar bands (DIBs). In early-type stars, narrow correlations exist between the DIB equivalent widths and the column density of interstellar material, and therefore the line-of-sight extinction. Here, we measure the equivalent widths of the 5780 and 6614 Å DIB features in a sample of actively accreting YSOs, and apply a DIB-reddening calibration to estimate reddening and subsequently extinction. Our calibration is newly derived from a composite of available literature data and fully accounts for the scatter in these measurements. We also compare the DIBs-inferred optical line-of-sight extinction values with previous extinction estimates for our sample stars
Plant biomacromolecule delivery methods in the 21st century
The 21st century witnessed a boom in plant genomics and gene characterization studies through RNA interference and site-directed mutagenesis. Specifically, the last 15 years marked a rapid increase in discovering and implementing different genome editing techniques. Methods to deliver gene editing reagents have also attempted to keep pace with the discovery and implementation of gene editing tools in plants. As a result, various transient/stable, quick/lengthy, expensive (requiring specialized equipment)/inexpensive, and versatile/specific (species, developmental stage, or tissue) methods were developed. A brief account of these methods with emphasis on recent developments is provided in this review article. Additionally, the strengths and limitations of each method are listed to allow the reader to select the most appropriate method for their specific studies. Finally, a perspective for future developments and needs in this research area is presented
Formation of robust bound states of interacting microwave photons
Systems of correlated particles appear in many fields of modern science and represent some of the most intractable computational problems in nature. The computational challenge in these systems arises when interactions become comparable to other energy scales, which makes the state of each particle depend on all other particles. The lack of general solutions for the three-body problem and acceptable theory for strongly correlated electrons shows that our understanding of correlated systems fades when the particle number or the interaction strength increases. One of the hallmarks of interacting systems is the formation of multiparticle bound states. Here we develop a high-fidelity parameterizable fSim gate and implement the periodic quantum circuit of the spin-½ XXZ model in a ring of 24 superconducting qubits. We study the propagation of these excitations and observe their bound nature for up to five photons. We devise a phase-sensitive method for constructing the few-body spectrum of the bound states and extract their pseudo-charge by introducing a synthetic flux. By introducing interactions between the ring and additional qubits, we observe an unexpected resilience of the bound states to integrability breaking. This finding goes against the idea that bound states in non-integrable systems are unstable when their energies overlap with the continuum spectrum. Our work provides experimental evidence for bound states of interacting photons and discovers their stability beyond the integrability limit
Global reorganization of deep-sea circulation and carbon storage after the last ice age
Using new and published marine fossil radiocarbon (¹⁴C/C) measurements, a tracer uniquely sensitive to circulation and air-sea gas exchange, we establish several benchmarks for Atlantic, Southern, and Pacific deep-sea circulation and ventilation since the last ice age. We find the most ¹⁴C-depleted water in glacial Pacific bottom depths, rather than the mid-depths as they are today, which is best explained by a slowdown in glacial deep-sea overturning in addition to a “flipped” glacial Pacific overturning configuration. These observations cannot be produced by changes in air-sea gas exchange alone, and they underscore the major role for changes in the overturning circulation for glacial deep-sea carbon storage in the vast Pacific abyss and the concomitant drawdown of atmospheric CO₂
Search for invisible decays of the Higgs boson produced via vector boson fusion in proton-proton collisions at √s = 13 TeV
A search for invisible decays of the Higgs boson produced via vector boson fusion (VBF) has been performed with 101 fb⁻¹ of proton-proton collisions delivered by the LHC at √s = 13 TeV and collected by the CMS detector in 2017 and 2018. The sensitivity to the VBF production mechanism is enhanced by constructing two analysis categories, one based on missing transverse momentum and a second based on the properties of jets. In addition to control regions with Z and W boson candidate events, a highly populated control region, based on the production of a photon in association with jets, is used to constrain the dominant irreducible background from the invisible decay of a Z boson produced in association with jets. The results of this search are combined with all previous measurements in the VBF topology, based on data collected in 2012 (at √s = 8 TeV), 2015, and 2016, corresponding to integrated luminosities of 19.7,
2.3, and 36.3 fb⁻¹, respectively. The observed (expected) upper limit on the invisible branching fraction of the Higgs boson is found to be 0.18 (0.10) at the 95% confidence level, assuming the standard model production cross section. The results are also interpreted in the context of Higgs-portal models