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Càrrega del cuidador principal. Vivències, experiències i afrontament dels pares de nens amb paràlisi cerebral
No full textRelació entre el dolor, control motor i propiocepció cervicals en violinistes i violistes
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Informe de un caso clínico con alteración de los reflejos primarios tratado con la terapia del movimiento rítmico de H.Blomberg. Enfoque multidisciplinar
No full textSegmentation and classification of breast cancer pathologies in histological images based on morphological patterns
No full textPobreza y discapacidad en España
No full textEste número de Quaderns aborda de manera sintética los efectos que la discapacidad conlleva sobre el riesgo de pobreza de las personas discapacitadas y del resto de miembros de sus hogares. En concreto, consta de dos partes claramente diferenciadas. La primera se centra en la relación establecida entre pobreza y discapacidad; la segunda parte estudia el gasto que los hogares con personas discapacitadas realizan para atender la discapacidad
Anthocyanin Tissue Bioavailability in Animals: Possible Implications for Human Health. A Systematic Review
No full textArticle publicat en Open AccesAnthocyanins (ACNs) are promising health-enhancing phenolic compounds. We focus on ACN animal tissue bioavailability to provide an evidentiary link between tissue ACNs and their associated health properties. We performed a systematic review of electronic libraries; 279 results were retrieved, and 13 publications met inclusion criteria. Extracted information included animal model employed, administration route, doses, analysis method, and ACN concentration values in tissues. Total ACN concentrations were detected in mice kidney (2.17 × 105 pmol/g), liver (1.73 × 105 pmol/g), heart (3.6 × 103 pmol/g), and lung (1.16 × 105 pmol/g); and in pig brain (6.08 × 103 pmol/g). ACNs showed a predominance of parent ACNs in long-term experiments versus an ACN metabolite predominance in short-term experiments. ACNs detected in animal tissues, such as cyanidin-3-glucoside, suggest it may have an important role in human health. This information could be useful to determine proper ACN-intake biomarkers in biological samples in futures studies
Endothelial cells ability to deconjugate resveratrol metabolites to free resveratrol: possible role in tissue factor modulation
No full textAdjunto la versió pre-print però també enviaré per correu la versió post-print.Scope. The antithrombotic effect of resveratrol (RV) and its forms remains unknown. The objective is to evaluate the effect of RV, its glucoside form piceid, and its biological metabolites (RV-3-O-β-D-Glucuronide, RV-4’-O-D-Glucuronide, and RV-3-O-Sulfate) on Tissue Factor (TF) modulation. Moreover, the endothelial metabolism of RV is assessed. Methods and results. Human aortic endothelial cells were incubated with trans-piceid, trans-RV, or its biological metabolites and stimulated with TNF-α. TF activity, protein, and mRNA expression were determined in cell lysates. Moreover, RV conjugation (phase II metabolism) to its sulphated or glucuronidated metabolites and their deconjugation to their parent compound (free RV) were also assessed in cell lysates and culture media. RV decreased TF activity, protein, and mRNA expression whereas piceid and RV metabolites showed no effects. RV-3-O-Sulfate was the main metabolite generated in the endothelium, while RV metabolites were deconjugated to free RV. Trans-RV and its trans-metabolites isomerization was observed generating their cis-forms. Conclusions. RV boasts antithrombotic effects modulating TF. RV metabolites and piceid did not show this effect. However, endothelial cells capacity to deconjugate RV metabolites to free RV indicates that RV metabolites can act as an endothelial reservoir for RV regeneration contributing to the antithrombotic effects of RV
¿El Smart Valley del sur de Cataluña? La (re)construcción tecnosimbólica de Tarragona
No full textEl objetivo de este artículo es analizar el estado de las iniciativas Smart City en la ciudad de Tarragona realizando una especial atención a la construcción retórica en relación con el concepto. Se parte de una contextualización de las dos principales políticas involucradas en la transformación de Tarragona en una ciudad inteligente. Mediante el examen del caso concreto de la Tabacalera, una antigua fábrica industrial en proceso de reconversión smart, se pretende ofrecer una muestra de las contradicciones y problemáticas que afronta esta estrategia urbana