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How to position Amorim sports as the recognized leader in sustainable and high-performance solutions for the turf sports fields? - segmentation, targeting and positioning
No full textAmorim Sports’ is a new business-to-business company from Amorim Cork Composites which specializes in sustainable and high-performance sports surfaces solutions, infills and shock pads made from cork or cork composites intended for use in sports systems. This report aims at examining how to position Amorim Sports as the recognized leader in sustainable and high-performance solutions for the turf sports fields, analyzing the worldwide market environment in which the company is involved. Hence, the Work Project presents a strategic marketing plan and an integrated marketing communication plan for the brand to achieve this challenge
I2 therapeutics: business plan
No full textCancer is a leading cause of death world wide. Despite Big Pharma companies spending high amounts of resources on Research and Development of new drugs, their effectiveness leaves much to be desired. Our biotech start up “I2 Therapeutics” addresses this gap in the market with a novel science-based solution called Syderum. Syderum is a system for targeted drug delivery to cancer cells whiles paring healthy tissue. Thus, harmful side effects of chemotherapy can be alleviated, and patient’s lives can be improved. The implications of this piece of work are foundation a las going for ward with this company could provide significantly better care for a large portion of the patient population and an advance men of the economic and social conditions in the communities in which I2 Therapeutics operates
Diabetes digital clinic: the starting point
No full textCovid-19 accelerated the digital transformation of health care, and new ways of delivering it emerged. This study aimed to explore how reorganizing care and delivering it through Integrated Practice Units would create value for patients. Three stakeholder groups were interviewed to ascertain the feasibility of a digital clinic in Portugal. The results suggested that implementing a digital clinic in Portugal is feasible, and among the pathologies considered, diabetes had the greatest receptivity for a digital setting by all stakeholders. Creating a digital clinic for diabetes in Portugal will then be a cutting-edge business model with tremendous potential
Analysis of supplier monitoring practices to promote long-term low-risk high-return manufacturer-supplier relationships
No full textWhile the business project developed risk mitigation strategies to improve the supplier selection
of the ABB group, this work project focuses on supplier monitoring. Specifically, supplier
monitoring practices are analyzed to create transparency and promote mutually beneficial long term manufacturer-supplier relationships. For this purpose, the monitoring methodology of a
subsidiary of ABB was analyzed to optimize the risk mitigation efforts of their supplier base.
While supply chain researchers recommend a multi-criteria risk assessment, this work found
that the manufacturer in this case only considered its dependence on its suppliers and their
financial health and disregarded other factor
Analysing sustainability reporting through the lens of the United Nations sustainable development goals: case study of Austria's listed companies
No full textThe United Nations Sustainable Development Goals are a crucial strategic topic for the coming decade. They aim to unite everyone in a call for action in the pursuit of universal welfare. In recent years, we have seen an important rise in adoption of these goals by the business world, which plays a major role in the transition to a sustainable future. This paper seeks to study Austrian companies’ commitment to the SDGs by coupling them with the Triple Bottom Line dimensions. It concludes by suggesting recommendations on how to further accelerate and deepen this engagement
A importância do Acordo EEE para o papel dos EEA Grants nas relações bilaterais entre Noruega e Portugal
No full textEste relatório tem como objetivo apresentar a experiência de um estágio curricular
realizado na Embaixada de Portugal em Oslo, com duração de seis meses, de 15 de
outubro de 2023 a 15 de abril de 2024. Esta oportunidade surgiu através do Programa de
Estágios do Ministério dos Negócios Estrangeiros (PECMNE), promovido pelo
Ministério dos Negócios Estrangeiros.
A criação do Acordo sobre o Espaço Económico Europeu contribuiu
significativamente para o fortalecimento das relações bilaterais entre diversos países e a
Europa, incluindo Portugal e Noruega, cujas relações têm vindo a desenvolver-se ao
longo do tempo. Neste sentido, além de descrever o trabalho realizado na Embaixada,
este relatório dedica uma parte do estudo à análise empírica da relevância do Acordo EEE
para as relações bilaterais entre Portugal e Noruega, com foco especial na implementação
dos EEA Grants em Portugal.The aim of this report is to present the experience of a six-month curricular
internship at the Portuguese Embassy in Oslo, from October 15th 2023 to April 15th 2024.
This opportunity arose through the Internship Program of the Ministry of Foreign Affairs
(PECMNE), promoted by the Ministry of Foreign Affairs.
The creation of the Agreement on the European Economic Area has contributed
significantly to strengthening bilateral relations between various countries and Europe,
including Portugal and Norway, whose relations have been developing over time. In this
sense, as well as describing the work carried out at the Embassy, this report devotes part
of the study to an empirical analysis of the relevance of the EEA Agreement for bilateral
relations between Portugal and Norway, with a special focus on the implementation of
EEA Grants in Portuga
Exploring the link between iron availability and fluconazole activity against Candida glabrata
No full text"Invasive fungal infections (IFIs) represent a significant health concern worldwide, as recently acknowledged by the World Health Organization with the release of the first priority list of fungal pathogens. Fluconazole remains the most frequently prescribed antifungal for treating IFIs due to its
affordability, oral bioavailability, broad spectrum of activity, and safety profile. This triazole drug targets
lanosterol 14α-demethylase, Erg11, an enzyme that catalyzes the conversion of lanosterol to ergosterol,
whose inhibition arrests cell growth by causing the accumulation of toxic sterols and depletion of ergosterol, which together compromise membrane integrity. Iron overload has been shown to promote
fungal growth and is considered a significant risk factor for IFIs. Preliminary results from our laboratory suggest that iron-loading conditions reduce the antifungal activity of fluconazole against Candida glabrata, the second most prevalent cause of these infections.(...)"N/
Secondary economic impacts of Food Aid Programs : a systematic review
No full textABSTRACT - Background: It is estimated that 47% of the global population cannot afford a healthy diet. The number of individuals facing food insecurity and hunger is rising, leading to an economic and food crisis. Food assistance programmes (FAPs) play a vital role in providing a safety net for individuals and families, significantly impacting their well-being. Therefore, the study aims to understand the overall impact of FAPs on secondary economic indicators.
Methods: A systematic review was conducted to identify relevant literature. PubMed, Web of Science, Scopus, Cochrane, and JSTOR databases were used. The search scope encompassed peer-reviewed journal articles published in English and Portuguese between 2013 and March 2023.
Results: The search yielded 4,189 articles, of which 13 met the inclusion criteria and covered different forms of FAPs across the USA, UK, Rwanda, and East Africa. Most studies employed quasi-experimental designs, while two employed cluster randomized trials and three employed quantitative methodologies. Eleven studies were assessed to be of moderate quality. The various forms of FAPs included in the review were found to have complex effects on different outcomes, although FAPs was found to have a positive effect on increasing employment and total income for households.
Conclusion: When effectively designed and implemented, FAPs have the potential to break the cycle of poverty. They address immediate food insecurity and promote economic stability for families. By improving access to nutritious food, supporting educational outcomes, and increasing employment opportunities, FAPs can contribute to long-term poverty relief efforts.RESUMO - Enquadramento: Estima-se que 47% da população mundial não tem recursos para uma alimentação saudável, observando-se um aumento na insegurança alimentar, o que esta a contribuir para crise económica. Os Programas de Ajuda Alimentar (PAA) são essenciais para criar uma rede de segurança e melhorar o bem-estar. O estudo visa compreender o impacto dos PAA nos indicadores económicos secundários.
Métodos: Foi realizada uma revisão sistemática para identificar a literatura relevante. As bases de dados utilizadas foram PubMed, Web of Science, Scopus, Cochrane e JSTOR. A pesquisa abrangeu artigos de revistas com revisão por pares, publicados em inglês e português, entre 2013 e março de 2023.
Resultados: A pesquisa produziu 4.189 artigos, dos quais 13 cumpriam os critérios de inclusão, abordando diversas formas de PAA em três países e na África Oriental. A maioria utilizou modelos quase-experimentais, com dois ensaios aleatórios e três estudos quantitativos. Onze estudos foram considerados de qualidade moderada. Os PAA mostraram efeitos complexos, mas de forma geral, demostraram um efeito positivo no aumento do emprego e do rendimento total das famílias.
Conclusão: Quando concebidos e implementados de forma eficaz, os PAA têm o potencial de quebrar o ciclo da pobreza. Abordam a insegurança alimentar imediata e promovem a estabilidade económica das famílias. Ao melhorar o acesso a alimentos nutritivos, apoiar os resultados escolares e aumentar as oportunidades de emprego, os PAA podem contribuir significativamente para os esforços de alívio da pobreza a longo prazo
Understanding how Streptococcus pneumoniae adapts to stresses imposed by innate immunity
No full text"Streptococcus pneumoniae is a commensal microorganism in the human nasopharynx
that can become pathogenic when invading sterile body regions, leading to difficult-to-treat
infections due to strain diversity and antibiotic resistance. The innate immune response to S.
pneumoniae is primarily driven by phagocytes like macrophages, which generate antimicrobial
reactive oxygen species (ROS) and reactive nitrogen species (RNS). To survive, S. pneumoniae
has evolved mechanisms to resist these stresses and relies heavily on glucose metabolism for
survival at infection sites. While phosphotransferase systems (PTS) are linked to stress resistance
in other Gram-positive bacteria, their role in the pneumococcus remains poorly understood.(...)
A targeted approach to control Streptococcus pneumoniae infection
No full text"The human upper respiratory tract (URT) hosts diverse bacterial communities, with the Streptococcus genus playing a key role in health and disease. Among these, S. pneumoniae
can asymptomatically colonize the URT in biofilms, facilitating its persistence, transmission, and potential progression to diseases like pneumonia, meningitis, sepsis and severe
secondary infections after influenza A (IAV). While antibiotics and pneumococcal conjugate vaccines (PCVs) have successfully reduced the disease burden, challenges like antibiotic
resistance and limited serotype coverage require alternative approaches. Targeting colonization, leveraging colonization resistance by commensals such as S. mitis and S. oralis,
and using antimicrobial peptides like bacteriocins, offer promising strategies to inhibit pathogens and combat pneumococcal disease more effectively.(...)"N/