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Agostinho Neto and Biographical Historiography
No full textIn this study, the practices of the biographical writing on Agostinho Neto are scrutinized. The analytical apparatus used shows that this historiography was hegemonised over a long period of time by celebratory and hagiographic narrative, not based on research and featuring both an internationalist school and an exclusively Portuguese-speaking nationalistic school, which are both made up of non-academic and literary academic intellectuals connected to political activism. It also reveals a recent and non-academic trend for writing critical historical biographies, more focused on sources but driven by a political agenda and not by the historiographic debate, which gives a teratographic bias. Other solutions are suggested in the final sections and it is argued that the recent evolution of the academic biographical historiography in Southern Africa shows that the parallel path of Hagiography with Diabolization is not inevitable
Saliva protein composition relates with inter-individual variations in bread sensory ratings
No full textSensory perception of starch‐based products associates with salivary α‐amylase enzymatic activity. Besides this, other proteins relate to taste sensitivity and oral food processing. As such, the participation of different salivary constituents in starch‐rich food's sensory evaluation cannot be excluded. This study aims to identify salivary proteins altered by bread mastication and correlated with sensory ratings. In Experiment 1 the effect of bread mastication in α‐amylase enzymatic activity and SDS PAGE profiles between is assessed (N = 64). In Experiment 2, a sub‐sample of these individuals (N = 22) is subjected to sensory tests and the sensory ratings obtained are correlated with saliva protein composition. Salivary α‐amylase activity, in the supernatant of saliva collected after bread mastication, is negatively correlated with sweetness and saltiness ratings. Moreover, saltiness is positively correlated with the expression levels of carbonic anhydrase VI. Bread roughness presented a positive association with α‐amylase enzymatic activity and a negative association with S‐type cystatin expression levels. Despite further studies are needed to clarify the negative association between salivary amylase enzymatic activity and sweetness ratings, observed in this study, these results reinforce the role of α‐amylase and highlights that other salivary proteins can also influence starch‐based sensory perception
Changes in the salivary proteome of beagle dogs after weight loss
No full textBeing overweight or obese represents an important health issue in humans and pets. The aim of this study was to investigate changes in the salivary proteome of overweight beagles after induced weight loss to better understand the physiological changes involved in this process. Five overweight/obese neutered males of pure breed beagles were evaluated. During the 3-mo period of weight loss, each animal received a strictly controlled amount of a low fat commercial diet per day. Body condition scores (BCS), body weight (BW), and serum biochemical parameters (total cholesterol, triglycerides, and C-reactive protein) were assessed weekly. Quantitative proteomics analysis by SWATH was used to evaluate the salivary proteome changes induced by weight loss treatment. BCS, BW, serum total cholesterol concentration, and abundances of 23 salivary proteins differed significantly between before and after treatment. Some of the altered protein amounts, namely of peptidyl-prolyl cis-trans isomerase, fructose-bisphosphate aldolase C, and 78-kDa glucose-regulated protein, increased after weight loss. These proteins are related with the immune system, inflammatory status, oxidative stress, and glucose metabolism. The results obtained suggest a potential use of salivary proteins in monitoring physiological changes in dogs subjected to weight loss. Moreover, the type of changes identified reinforces the postulated physiological improvements, which weight loss induces. Further research is needed to determine whether the changes observed in this study are due to weight loss, dietary changes, or a combination of both
Apreensão do princípio alfabético
No full textO princípio alfabético é o fundamento dos sistemas de escrita alfabética. Segundo esse princípio, cada fonema é associado a um grafema. Entender como esse princípio opera é essencial para a aprendizagem da leitura e da escrita, servindo de base à aprendizagem das correspondências do código ortográfico e dos mecanismos de decodificação e codificação. Este vídeo aborda estratégias para levar o leitor aprendiz a apreender o princípio alfabético
Genetic variants in the IFNGR2 locus associated with severe chronic Q fever
Get PDFQ fever is a highly contagious zoonosis capable of causing large outbreaks of important health and economic consequences. Host genetic factors are believed to influence the development of severe chronic Q fever following the infection by the etiological agent, Coxiella burnetii. Targetted next generation sequencing (NGS) was performed in a case-control genetic association study on 53 confirmed Q fever cases, including 38 compatible with acute and 15 with chronic disease, and 29 samples from the general Portuguese population. Four SNPs in the IFNGR2 locus, rs78407108 G > A, rs17879956 C > T, rs7277167 C > T, and rs9974603 C > A, showed a statistically significant association to chronic Q fever, resisting the Bonferroni correction. These belonged to haplotypes significantly associated with chronic Q fever. The individual SNPs are referenced in the GTEx database as possible eQTLs. Given the direct bearing of IFNGR2 on IFN-γ signaling, the possible involvement of the associated variants with higher IFNGR2 expression could be in line with observations suggesting that IFN-γ production in chronic Q fever patients is significantly higher than in healthy controls. Further investigations are required to clarify the role of IFNGR2 signaling in association with chronic Q fever
Non-Ergodic Theory vs. Fractal Geometry in Organizational Learning and Dynamic Skills at a Healthcare Food Catering Service
Get PDFThis paper examines the adoption of non-Ergodic Theory and Fractal Geometry to enhance organizational learning in healthcare food catering. It critiques conventional linear models, promoting an understanding of varied learning processes across organizational strata. Non-Ergodic Theory emphasizes the diversity of learning among individuals and groups, while Fractal Geometry examines learning as self-similar patterns at multiple scales. This work analyses how employee diversity, knowledge sharing, and cross-level collaboration contribute to a fractal learning environment that supports adaptability and innovation. Findings indicate that implementing these theoretical models can enhance service delivery and customer approval by promoting a culture of relentless education and creative ideas. For managers and practitioners, this study provides a blueprint for enhancing learning processes that can lead to greater efficiency and performance in healthcare food services, suggesting a strategic embrace of employee diversity and interconnected learning patterns for long-term organizational success
Fisiopatologia da urolitíase em gatos e abordagens cirúrgicas na resolução da obstrução ureteral
Get PDFA urolitíase é a principal causa de obstrução ureteral em pequenos animais. Uma das principais preocupações é a diminuição da função renal, que promove a instabilidade do animal. Desta forma, deve instituir-se de forma imediata, uma terapêutica médica, embora esta seja raramente curativa, tendo que se optar, muito frequentemente, por uma terapêutica mais avançada, como é o caso da cirurgia. Este relatório de estágio pretende realizar, para além de uma revisão bibliográfica relativa à obstrução ureteral por urolitíase, a apresentação de dois casos clínicos, cujo objetivo passou por demonstrar a eficácia de técnicas cirúrgicas, como a ureterotomia e o Bypass Ureteral Subcutâneo, para a sua resolução, bem como as suas complicações pós-operatórias, num total de oito gatos submetidos a um destes procedimentos no Anicura Atlântico Hospital Veterinário; - ABSTRACT:
“Pathophysiology of urolithiasis in cats and surgical approaches to resolving ureteral obstructions”
Urolithiasis is the main cause of ureteral obstruction in small animals. One of the main concerns is the decrease in kidney function, which causes the animal to become unstable. Therefore, medical treatment should be instituted immediately, although this is rarely curative, and very often more advanced treatment, such as surgery, has to be chosen. In addition to a literature review on ureteral obstruction due to urolithiasis, this internship report presents two clinical cases, the aim of which was to demonstrate the effectiveness of surgical techniques such as ureterotomy and subcutaneous ureteral bypass in resolving ureteral obstruction, as well as their post-operative complications, in a total of eight cats that underwent one of these procedures at Anicura Atlântico Veterinary Hospital
Clínica e cirurgia de animais de companhia
No full textO presente relatório descreve o estágio curricular para conclusão do Mestrado Integrado em Medicina Veterinária, realizado no Hospital Veterinário Muralha de Évora, sob orientação interna do professor Dr Hélder Cortes e orientação externa da Drª Margarida Costa.
Assim, descreve uma análise da casuística observada durante o estágio nas diferentes áreas clínicas. Seguidamente, aborda uma monografia que engloba a poliúria/polidipsia (Pu/Pd) em cães e gatos numa perspetiva diagnóstica, seguindo-se a apresentação de dois casos clínicos sobre o tema.
Entende-se por poliúria (Pu) a produção consciente de elevada quantidade de urina, não correlacionado com sinais específicos do trato urinário, e polidipsia (Pd) como um aumento excessivo do consumo de água. Existem inúmeras causas que podem originar esta sintomatologia, sendo elas de origem renal, endócrina, infeciosa, eletrolítica, hepática, comportamental, neurológica ou tumoral.
Os médicos veterinários podem usar elementos-chave relevantes no diagnóstico, como medição da densidade urinária (DU), concentrações plasmáticas de iões e urianálise, para priorizar a lista de diferenciais e simplificar o diagnóstico; - PET ANIMAL CLINIC AND SURGERY
ABSTRACT:
This report describes the curricular internship of the Integrated Master's Degree in Veterinary Medicine, carried out at the Muralha Veterinary Hospital in Évora, under the internal supervision of Professor Dr Hélder Cortes and the external supervision of Drª. Margarida Costa.
It describes an analysis of the casuistry observed during the internship in the different clinical areas. She then discusses a monograph on polyuria/polydipsia (Pu/Pd) in dogs and cats from a diagnostic perspective, followed by a presentation of two clinical cases on the subject.
Polyuria (Pu) is defined as the conscious production of a large quantity of urine, not correlated with specific signs of the urinary tract, and polydipsia (Pd) as an excessive increase in water consumption. There are numerous causes that can lead to this symptomatology, including renal, endocrine, infectious, electrolytic, hepatic, behavioral, neurological and tumor causes.
Veterinarians can use relevant key elements in the diagnosis, such as measuring urinary density (DU), plasma ion concentrations and urinalysis, to prioritize the list of differentials and simplify the diagnosis
A pele como um espelho da saúde interna: Calcinose Cutânea no Hiperadrenocorticismo
Get PDFEste relatório foi elaborado como parte da conclusão do Mestrado Integrado em Medicina
Veterinária da Universidade de Évora e está dividido em três partes. A primeira apresenta
uma análise estatística dos casos acompanhados durante o estágio curricular, realizado
entre dois de outubro de 2023 e 31 de março de 2024. A segunda consiste numa
monografia sobre “A pele como um espelho da saúde interna: Calcinose Cutânea no
Hiperadrenocorticismo”. A calcinose cutânea é uma afeção pouco frequente,
caracterizada por níveis normais de cálcio sérico, mas com depósitos elevados de sais de
cálcio insolúveis na pele e no tecido subcutâneo, sendo crucial controlar a condição
subjacente, sendo a calcinosis cutis altamente sugestiva de disfunção da glândula adrenal,
ou seja, de um diagnóstico de hiperadrenocorticismo. A terceira parte inclui a
apresentação e discussão de um caso clínico específico, em cão com esta afeção; - Abstract:
The skin as a mirror of the internal health: Calcinosis Cutis in Hyperadrenocorticism
This report was prepared as part of the completion of the Master's degree in Veterinary
Medicine of the University of Évora and is divided into three sections. The first presents
a statistical analysis of the cases followed during the internship, from October two of
2023 to March 31 of 2024.The second consists of a monograph about “The skin as a
mirror of the internal health: Calcinosis Cutis in Hyperadrenocorticism”. Calcinosis cutis
is a very rare pathology characterized by normal serum calcium levels but elevated
deposits of insoluble calcium salts in the skin and subcutaneous tissue. It is crucial to
control the underlying condition, as the presence of calcinosis cutis is highly suggestive
of adrenal gland dysfunction, that is, a diagnosis of hyperadrenocorticism. The third
section includes the presentation and discussion of a specific clinical case, in a dog, that
exhibited this affection
Turismo cultural e criativo: o caso da Empresa de Animação Turística Tours Évora Genuína
No full textOs segmentos relacionados com o turismo cultural e criativo são cada vez mais reconhecidos
na área do turismo como fundamentais para a diversificação da oferta turística e para a
satisfação do consumidor.
O turismo cultural envolve experiências que enfatizam a herança cultural e histórica de um
destino, enquanto o turismo criativo promove experiências que exploram a criatividade local,
nomeadamente, através das expressões artísticas, da música, gastronomia, design, etc.
Neste enquadramento, a animação turística desempenha um papel importante na resposta às
motivações desses nichos de mercado, uma vez que cria e implementa novos conceitos de
experiências que integram os turistas e visitantes no contexto cultural e turístico dos destinos.
Isso pode incluir atividades como passeios temáticos, workshops de artesanato local, festivais
culturais, entre outros, contribuindo para a melhoria da imagem de um destino turístico. Essas
experiências não só oferecem aos turistas uma oportunidade única para imergirem na cultura
local, mas também contribuem para o desenvolvimento económico das comunidades,
promovendo o património cultural e incentivando a participação das comunidades locais na
indústria do turismo. Ou seja, o turismo cultural e criativo e a animação turística desempenham
um papel crucial na diversificação da oferta turística e na criação de experiências significativas
para os turistas e visitantes, ajudando a promover os destinos de forma autêntica e
sustentável.
A presente dissertação pretende caracterizar o perfil sociodemográfico do cliente da empresa
“Tours Évora Genuína”, identificar as motivações dos clientes, assim como, obter o feedback
das respetivas experiências vividas e aferir também o grau de satisfação dos clientes. Para
atingir os objetivos foi adotada uma abordagem quantitativa através do inquérito por
questionário. Com este trabalho pretende-se apurar a qualidade do desempenho dos serviços
prestados aos turistas e visitantes por parte da empresa, identificando o perfil do respetivo
cliente, o qual traduz, de algum modo, o tipo de turista e visitante que se verifica no Concelho
de Évora. Para o efeito, utilizou-se o modelo SERVPERF (Cronin e Taylor, 1992), no qual a
avaliação da qualidade dos serviços decorre do resultado direto da perceção de desempenho.
Este modelo utiliza as perceções do consumidor em relação ao desempenho da empresa, de
forma a avaliar da qualidade do serviço prestado; - Cultural and Creative Tourism: The case of the Tourist Company Tours Évora Genuína
Abstract:
Segments related to cultural and creative tourism are increasingly recognized in the tourism
sector as fundamental for the diversification of tourist offer and for consumer satisfaction.
Cultural tourism involves experiences that emphasize the cultural and historical heritage of a
destination, while creative tourism promotes experiences that explore local creativity, namely
through artistic expressions, music, gastronomy, design, etc.
In this context, tourist entertainment plays an important role in responding to the motivations
of these niche markets, as it creates and implements new concepts of experiences that
integrate tourists and visitors into the cultural and tourist context of destinations. This may
include activities such as themed tours, local craft workshops, cultural festivals, among others,
contributing to improving the image of a tourist destination.
These experiences not only offer tourists a unique opportunity to immerse themselves in local
culture, but also contribute to the economic development of communities, promoting cultural
heritage and encouraging local communities' participation in the tourism industry.
So, cultural and creative tourism and tourist entertainment play a crucial role in diversifying the
tourist offer and creating meaningful experiences for tourists and visitors, helping to promote
the destinations in an authentic and sustainable way.
Therefore, this dissertation aims to characterize the sociodemographic profile of the customer
of the company “Tours Évora Genuína”, to identify the motivations of customers, as well as, to
get their feedback related to the respective lived experiences and also to assess the level of
customer satisfaction. To achieve the goals, a quantitative approach was adopted using a
questionnaire survey. The aim of this study is to ascertain the quality of the services provided
to tourists and visitors, identifying the profile of the respective client, which reflects, to some
extent, the type of tourist and visitor found in the Municipality of Évora. To this end, the
SERVPERF model (Cronin and Taylor, 1992) was used, in which the evaluation of service
quality is the direct result of perceived performance. This model uses consumer perceptions of
the company's performance to assess the quality of the service provided