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Ipotesi di definizione di nuovi fattori prognostici nel carcinoma gastrico: ruolo dell'infiltrato linfoplasmacellulare
No full textDevelopment of a steady state simulation code for klystrons
No full textThe design of klystrons is based on the intensive utilization of simulation codes, which can evaluate the complete beam-cavities interaction in the case of large signals. In the present work, we present the development of a 2-D steady state simulation code that can self-consistently evaluate the effects of the electromagnetic field on the particles and of the particles back on the field. The algorithm is based on the iterative solution of the power balance equation in the RF structures and it allows determining the amplitude and phase of the electromagnetic field starting from the cavity modes. Some applications of the code to a single cavity and a two cavity klystron are presented and compared with the results obtained from theory and from another code. Effects of space charge forces in the drift tubes are also evaluated.Stanford Linear Accelerator Center (SLAC
Le endoprotesi esofagee nel trattamento endoscopico delle stenosi esofagee maligne: attualità e sviluppo.
No full textResistere creativamente. Il design di denuncia politica
No full textIn this work we aim at investigating categories of product design in terms of cultural communication by exploring artefacts conceived with the intent of encouraging users’ reflection upon “conflict” issues. Under this light, we have chosen case studies referred to those conflicts in which walls and fences are still separating populations one from another, as for Palestine, Mexico, etc.
The conflict is here read as an event that is able to encode expectations of emancipation, and because of that it becomes central for articulating significant transitions. Such artefacts, rather than for their functionality or utility, might be interpreted through the Stephanie and Bruce Tharp theory of discursive design, where objects are treated like transmitters of ideas and messages. We believe that discursive design can be a good starting point for better understanding the value of the semantic content spread by objects within
time and space, and that artefacts can be considered as specific agents of communication. Therefore, if we consider objects as communicative facts, then we can use tools taken from the field of logics and linguistics in order to analyse the semantic and the cultural length of the objects themselves. As a consequence, politically engaged design tends to broaden the role of designers into an intellectual one, being able to boost debates around the issues designers trigger
Investigation of Structure-Function Relationship of Biomolecules, using Infrared Spectroscopic, Thermodynamic and Brewster Angle Microscopy Analyses
No full textBiomolecules are organic molecules that are biologically important. Examples of biomolecules include nucleic acids; deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), proteins; filamentous (e.g. actin filaments and microtubules) and globular (e.g. hemoglobin that transports oxygen in bodies), carbohydrates and lipids. The transport of biomolecules on the nano- and micro-length scale is of interest to a number of scientists and engineering communities, ranging from life and chemical sciences to engineering and mathematics.
With increasing use of biomolecules in a very broad range of applications, there has emerged a critical need to their structural characterization in diverse environments. Proteins participate in numerous functions within living organisms and it is well established that the biological function is highly dependent on the molecule's conformation that corresponds to its three-dimensional structure which may change according to surrounding natural or artificial environments. Many diseases are caused by proteins whose structures have been modified, either due to amino acid substitutions resulting from DNA changes (Anemia and Cancer) or by incorrect protein folding (Alzheimer).
Interactions of proteins with lipids are the area of fundamental interest due to enormous biological importance. From the biotechnological and biomedical applications point of view, studies on lipids and proteins have been playing a significant role in developing protocols for drug delivery and immune-sensing system, various bio-molecular devices etc. The immobilization of protein without denaturation on solid support, or on lipid membrane, is extremely valuable and is the fundamental step for designing such devices.
In this context, this thesis is focalized on investigating the structure-to-function twin relationship of different biomolecules (enzymes, polymers and lipids), employing a number of techniques to provide a supplementary input to this up-to-minute research field. That is it, different approaches on different biological systems but all evolving around a single aim in addressing the specific interactions leading to the unique features and functions. Different techniques will be used to characterize the interaction mechanisms, including infrared spectroscopy, Langmuir thermodynamic studies and Brewster angle microscopy
La città pubblica. Problemi e strategie della costruzione e della riqualificazione
No full textDoctoral Thesis on Social Housing urban regenration issue
