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    A wordbook of rare mithers: Womclemd

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    A quarterly periodical exploring the county of Cheshire, the city of Chester and its dialec

    Primogeniture in Turkish Family Owned Businesses: An examination of daughter succession, the impact of national culture on gendered norms and leadership challenge.

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    Family owned and controlled businesses, which may be owned, controlled or operated by various family members, account for an enormous percentage of global employment, revenues and GDP. Although the majority of well-known companies are family owned, research indicates that unfortunately, only thirty percent of family businesses survive to the second generation. Therefore, successful transfer of the business to the next generation is an important issue for the family business literature. However, although succession is a vital issue for Family Owned Businesses (FOBs), the process is unfortunately very gender biased in most societies, with boys being generally favoured over girls so daughters are always excluded as candidates and other women are seldom considered as successors in family businesses. In many cases, especially in certain cultures, female members of the next generation are not even perceived as a viable option. Even in today’s rapidly changing business climate, primogeniture continues to dominate the value system of family businesses. Primogeniture is an accepted approach to family business succession planning; daughters are only considered for family business succession when all descendants are female or the daughter is the first born. This study aims to identify the reasons behind the primogeniture in Turkish FOBs. The objectives of the study were to examine the key factors identified by the incumbents related with the primogeniture. In this research study, an interpretive methodology was adopted to explore, interpret and to understand meanings of knowledge. For this research, qualitative data were gathered via in-depth open-ended interviews with 20 male FOB owners who have at least one daughter and 20 daughters working at their FOB with their fathers. The questions were designed to measure different facets of FOB demographics and culture to understand their effects on the selection process within Turkish FOBs and gender norms in the context of FOB norms, which influence both family members and the business it. This study investigated daughters’ succession in FOBs in Turkey, a developing country where women are less likely than men to engage in entrepreneurial activities and show that gendered norms are still considered when choosing the successor, in other word, primogeniture still dominates the family business succession process

    Understanding minimum and ideal factor levels for participation in physical activities by people with haemophilia: An expert elicitation exercise

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    This article is not available on ChesterRepThe benefits of physical activity (PA) for people with haemophilia (PWH) may include improvements in joint, bone and muscle health. However, the factor VIII activity level required to avoid a bleeding episode associated with PA is unknown. To elicit the opinion of clinical experts on the minimum level and ideal factor VIII activity ('level') required to avoid a bleeding episode during participation in different types of PA for PWH. Based on the 2017 National Hemophilia Foundation PA descriptions, clinical experts estimated a minimally acceptable and an ideal factor level at which a bleed could be avoided. The uncertainty around estimates was quantified using an approach to construct a probability distribution to represent expert opinion. Minimum and ideal factor level increased with higher risk PA, whether or not joint morbidity was present, as did the experts' uncertainty in their estimates (ie the range between lowest and highest estimates for minimum and ideal levels). Mean minimum levels ranged from 4% to 48% for low to high risk for people without joint morbidity, and from 7% to 47% for those with joint morbidity. For ideal factor levels, corresponding figures were 9%-52% and 12%-64%, respectively. To support a patient-centric outcome, expert opinion indicates that the clinical norm of 0.01 IU/mL (1%) trough level is insufficient. It is anticipated that introducing a more targeted approach to meet the needs of patients who are increasingly physically active will benefit patients further in addition to recent treatment advances. [Abstract copyright: © 2020 John Wiley & Sons Ltd.

    Pro-Inflammatory Priming of Umbilical Cord Mesenchymal Stromal Cells Alters the Protein Cargo of Their Extracellular Vesicles

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    Umbilical cord mesenchymal stromal cells (UCMSCs) have shown an ability to modulate the immune system through the secretion of paracrine mediators, such as extracellular vesicles (EVs). However, the culture conditions that UCMSCs are grown in can alter their secretome and thereby affect their immunomodulatory potential. UCMSCs are commonly cultured at 21% O2 in vitro, but recent research is exploring their growth at lower oxygen conditions to emulate circulating oxygen levels in vivo. Additionally, a pro-inflammatory culture environment is known to enhance UCMSC anti-inflammatory potential. Therefore, this paper examined EVs from UCMSCs grown in normal oxygen (21% O2), low oxygen (5% O2) and pro-inflammatory conditions to see the impact of culture conditions on the EV profile. EVs were isolated from UCMSC conditioned media and characterised based on size, morphology and surface marker expression. EV protein cargo was analysed using a proximity-based extension assay. Results showed that EVs had a similar size and morphology. Differences were found in EV protein cargo, with pro-inflammatory primed EVs showing an increase in proteins associated with chemotaxis and angiogenesis. This showed that the UCMSC culture environment could alter the EV protein profile and might have downstream implications for their functions in immunomodulation

    The use of a positive mood induction video-clip to target eating behaviour in people with bulimia nervosa or binge eating disorder: An experimental study

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    Recent theoretical models and empirical research have indicated that momentary negative affect increases the likelihood of binge eating episodes for individuals with bulimia nervosa and binge eating disorder. However, relatively little research has explored the potential for positive mood to serve a protective effect in reducing the likelihood of overeating behaviour in bulimia nervosa and binge eating disorder. The current study included 30 women with bulimia nervosa or binge eating disorder in a within-subjects crossover design. Following exposure to a video designed to induce food craving, we found that a positive mood vodcast was associated with significantly lower levels of negative mood and food consumption in a taste test meal, when compared to a neutral vodcast (p = .002). These findings support a role for decreasing negative mood in reducing the likelihood of binge eating behaviour in women with bulimia nervosa and binge eating disorder

    An exploration of women’s experiences of emotional ambivalence during their first trimester of pregnancy and their perceptions of psychosocial support during that time

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    The first trimester is a vital stage of pregnancy. Many important developmental changes take place for both mother and baby during this time. These changes are vast and fast paced and encompass changes to a woman’s body, their emotional and also their social wellbeing. This qualitative study aimed to gain insight into women’s experiences of emotional ambivalence and their perception of psychosocial support during the stage of the first trimester of pregnancy. Through Interpretative Phenomenological Analysis (IPA), super-ordinate themes and sub-ordinate themes were identified. Hearing first-hand accounts of four women’s lived experiences highlighted the prevalence of emotional ambivalence during the first trimester. It also exposed the reality and impact of perceived support that was deemed beneficial including support from significant relationships and support that was considered lacking including emotional holding and individually-led support. This study has added to the conversation that there is scope for further research with the view to addressing women’s mental and emotional wellbeing and the standard of perceived support they receive during the first trimester of pregnancy

    Reduced Inequalities

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    A basic definition of trade barriers could be ‘all factors that influence the amount of goods and services shipped across international borders’ (Feenstra and Taylor, 2017a). This definition is quite neutral, and it needs to be understood that the word ‘barrier’ has a negative connotation, which means that a trade barrier would be any instrument that limits or restrict trade between countries, as opposed to free trade. It is generally accepted that free trade is good for productivity and economic growth, but it is also true that most countries apply some sort of trade restriction, for different reasons

    Perspectives on Adolescents’ Obesity Amidst the Nutrition Transition in Lebanon

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    Adolescent obesity is a major public health concern, increasingly affecting low and middle-income countries (LMICs) undergoing the nutrition transition. In developed countries, governments had the time to adjust to this rise in the consequent non-communicable diseases (NCDs), whereas the developing world is facing a triple burden of nutrition-related disease simultaneously. However, amidst the nutrition transition, drivers to obesity may differ within the same country especially between the urban and rural areas, depending on the context and environmental factors. In order to unravel how the nutrition transition process unfolds in both urban and rural areas, an exploration of the factors affecting adolescents’ lifestyle and eating behaviours, in the current context was deemed appropriate. Additionally, exploring stakeholders’ views on adolescents’ obesity including facilitators and barriers to obesity prevention is key in intervention and policy drawing. This study thus aimed to explore in-depth, whether, how, and to what extent is the nutrition transition currently affecting adolescents’ environments in Lebanon, focusing on both adolescents’ and stakeholders’ perspectives, awareness, and barriers to the prevention of adolescents’ obesity. The study used a sequential multi-method approach along a bricolage methodology. The first phase of the study adopted a qualitative approach, involving focus groups with adolescents (n = 78) to explore their perceptions regarding their eating behaviours as well as the role of the environment surrounding them in both urban and rural areas. A number of direct (availability of Western foods, peer pressure, parental control, eating location, body image) and indirect (adolescence autonomy, role modeling, cultural beliefs, peer surveillance) factors seemed to influence adolescents’ eating behaviours. Almost similar behaviours were perceived between the urban and rural area, showcasing the impact of the nutrition transition in both areas although different underlying factors were stated. The factors identified in this study were grouped and discussed based on the socioecological model (SEM) highlighting the importance of the social and environmental influences on adolescents’ eating behaviours. The second phase of the study adopted a qualitative approach; using one-to-one interviews to investigate stakeholders’ opinions on adolescents’ obesity. The study highlighted the barriers and facilitators in preventing adolescents’ obesity in relation to adolescents’ eating behaviours and the surrounding environment. Key stakeholders interviewed in this phase included different sectors such as the Ministry of Education, Municipalities, Transportation NGOs, with a special emphasis on the school setting including school directors, manager of school cafeteria, sports teacher, school nurse and head teacher. Interviews revealed the lack of awareness concerning the obesity problem and the importance of the environmental influences, a lack of intersectoral cooperation between stakeholders in Lebanon and a greater emphasis on the individual responsibility in the prevention of adolescents’ obesity. This study has revealed and engaged with the varied conceptualisations of obesity causation amongst adolescents, in both urban and rural areas, amid the nutrition transition in Lebanon. Acknowledging that the causes of obesity are complex this study collects insights of both adolescents and key stakeholders’ perceptions; to date, no study has engaged with both in Lebanon, justifying the need for the present study. Clearly, in keeping with the literature on the different rate of nutrition transition between rural and urban environments further justifies the consideration of both context. Given the findings of this study in regards to the dramatic changes affecting both urban and rural areas regarding the number of meals consumed away from home, the increase in fast-food consumption and the increase in sedentary lifestyles, new challenges in relation to adolescent obesity prevention in LMICs are created. The creation of supportive local environments, in both urban and rural areas, represents an important avenue where eating behaviours concerns, and thus adolescents’ obesity can be addressed

    Walking on Kendall’s Shape Space: Understanding Shape Spaces and Their Coordinate Systems

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    From Springer Nature via Jisc Publications RouterHistory: received 2020-05-30, registration 2020-08-10, accepted 2020-08-10, pub-electronic 2020-08-18, online 2020-08-18, pub-print 2020-12Publication status: PublishedFunder: University of ManchesterAbstract: More and more analyses of biological shapes are using the techniques of geometric morphometrics based on configurations of landmarks in two or three dimensions. A fundamental concept at the core of these analyses is Kendall’s shape space and local approximations to it by shape tangent spaces. Kendall’s shape space is complex because it is a curved surface and, for configurations with more than three landmarks, multidimensional. This paper uses the shape space for triangles, which is the surface of a sphere, to explore and visualize some properties of shape spaces and the respective tangent spaces. Considerations about the dimensionality of shape spaces are an important step in understanding them, and can offer a coordinate system that can translate between positions in the shape space and the corresponding landmark configurations and vice versa. By simulation studies “walking” along that are great circles around the shape space, each of them corresponding to the repeated application of a particular shape change, it is possible to grasp intuitively why shape spaces are curved and closed surfaces. From these considerations and the available information on shape spaces for configurations with more than three landmarks, the conclusion emerges that the approach using a tangent space approximation in general is valid for biological datasets. The quality of approximation depends on the scale of variation in the data, but existing analyses suggest this should be satisfactory to excellent in most empirical datasets

    Displaying the Dark Ages in Museums

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    How museums and heritage sites in England display the early medieval past is the focus of academic and public interest and debate. Despite ever-pressured budgets and limited resources, the stories told about the early medieval past in these environments are of key importance for the story of this island, and have become increasingly important in the context of political and cultural crises of English identity, and extremist appropriations of the Early Middle Ages. Reviewing current and past displays of early medieval material culture at the Museum of Liverpool, the World Museum (also in Liverpool), and Chester’s Grosvenor Museum, this chapter evaluates the Early Middle Ages in city museums serving multicultural regions in the English North West and West Midlands. Consequently, we identify recommendations for potential future museum engagement with the ‘Dark Ages’

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