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    Connecting nutrition as a hard science and international knowledge networks: Proceedings of the Fourth International Summit on Medical and Public Health Nutrition Education and Research

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    Nutrition is a 'hard' science in two ways; the scientific rigour required for quality nutrition research, and equally, the challenges faced in evidence translation. Ways in which quality nutrition research can be synthesised and evidence effectively translated into practice were the focus of the Fourth Annual International Summit on Medical and Public Health Nutrition Education and Research. Wolfson College, University of Cambridge, and Addenbrookes Hospital at the Cambridge Biomedical Campus, Cambridge, in July 2018. Open communication and collaboration across disciplines and systems, including transfer of knowledge, ideas and data through international knowledge application networks, was presented as a key tool in enhancing nutrition research and translation of evidence. Increasing basic nutrition competence and confidence in medical professionals is needed to encourage the implementation of nutrition therapy in prevention and treatment of health outcomes. A sustained focus on producing quality nutrition research must be coupled with increased efforts in collaboration and building of knowledge networks, including educating and training multidisciplinary health and medical professionals in nutrition. Such efforts are needed to ensure nutrition is both reliable in its messaging and effective in translation into healthcare. [Abstract copyright: © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

    Coping style and early life vocalizations in the Common Marmoset ( Callithrix jacchus )

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    The version of record of this article, first published in [International Journal of Primatology], is available online at Publisher’s website: http://dx.doi.org/10.1007/s10764-020-00153-8Coping styles describe behavioral differences during stressful or challenging situations. Coping styles are stable over time but little is known about early life manifestation and development of these behavioral differences. We aimed to investigate if differences in the way marmosets produce vocalizations at an early age are related to their coping style in the future. We studied 14 common marmosets (Callithrix jacchus) from three social groups housed at the marmoset colony at Universidad Autónoma de Madrid. We recorded the vocalizations of each marmoset in isolation at 15–17 days of age, analyzing latency to vocalize and calling rate of phee and tsik calls. To measure coping style, we introduced a novel stimulus to the group cages when infants were 3 months old and recorded exploration, headcocking, and approaches to the stimulus. The results showed negative relationships between the latency of phee call (a long-range contact call) at 15–17 days and frequency of exploration and approach to the novel stimulus at 3 months, although both correlations fall above the cut-off points for the false discovery rate. Marmosets that gave long-range calls sooner at 15–17 days of age also showed more exploratory behaviors at 3 months. The results also showed group differences in exploration at 3 months, and twins were more similar to each other than to other infants in the sample. There were no group differences in early vocalizations and no sex differences in any variable. These findings suggest that coping style is stable from as early as 15–17 days after birth and suggest that the group can influence exploration in marmosets

    What does safety in mental healthcare transitions mean for service users and other stakeholder groups: An open‐ended questionnaire study

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    From Wiley via Jisc Publications RouterHistory: received 2020-04-03, rev-recd 2020-11-30, accepted 2020-12-14, pub-electronic 2021-01-20, pub-print 2021-05Article version: VoRPublication status: PublishedFunder: NIHR Greater Manchester Patient Safety Translational Research Centre; Id: http://dx.doi.org/10.13039/501100013235Abstract: Background: Historically, safety mental health research has tended to focus on risks of homicide, suicide and deaths. Although wider safety issues are now recognized in regards to mental health services, the safety of mental health transitions, a key research and policy priority according to World Health Organisation, has not been explored. Objective: The purpose of this study was to investigate perceptions of safety in mental health transitions (hospital to community) amongst five stakeholder groups. Design and setting: An online, international cross‐sectional, open‐ended questionnaire. Participants: There were five stakeholder participant groups: service users; families/carers; mental health‐care professionals; researchers; and end users of research. Results: Ninety‐three participants from 12 different countries responded. Three overarching themes emerged: ‘individual/clinical’, ‘systems/services’ and ‘human, behavioural and social’ elements of safe mental health transitions. Whilst there was a great focus on clinical elements from researchers and healthcare professionals, service users and carers considered safety in terms of human, behavioural and social elements of transitional safety (ie loneliness, emotional readiness for discharge) and systems/services (ie inter‐professional communication). Discussion: Safety in mental health‐care transitions is perceived differently by service users and families compared to healthcare professionals and researchers. Traditional safety indicators for care transitions such as suicide, self‐harm and risk of adverse drug events are raised as important. However, service users and families in particular have a much wider perception of transitions safety. Conclusion: Future quality and safety research and policy should consider including a service user voice and consider integration of psychosocial elements in discharge interventions

    Shut and re-open: the role of schools in the spread of COVID-19 in Europe

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    From The Royal Society via Jisc Publications RouterHistory: accepted 2020-12-02, pub-electronic 2021-05-31, pub-print 2021-07-19Article version: VoRPublication status: PublishedFunder: Wellcome Trust; Id: http://dx.doi.org/10.13039/100004440; Grant(s): 202562/Z/16/ZFunder: Royal Society; Id: http://dx.doi.org/10.13039/501100000288; Grant(s): 202562/Z/16/ZFunder: Department for Health and Social CareFunder: Canadian Institutes of Health Research; Id: http://dx.doi.org/10.13039/501100000024; Grant(s): 2019 Novel Coronavirus (COVID-19) rapid researchFunder: Medical Research Council; Id: http://dx.doi.org/10.13039/501100000265; Grant(s): MC UU 00002/11We investigate the effect of school closure and subsequent reopening on the transmission of COVID-19, by considering Denmark, Norway, Sweden and German states as case studies. By comparing the growth rates in daily hospitalizations or confirmed cases under different interventions, we provide evidence that school closures contribute to a reduction in the growth rate approximately 7 days after implementation. Limited school attendance, such as older students sitting exams or the partial return of younger year groups, does not appear to significantly affect community transmission. In countries where community transmission is generally low, such as Denmark or Norway, a large-scale reopening of schools while controlling or suppressing the epidemic appears feasible. However, school reopening can contribute to statistically significant increases in the growth rate in countries like Germany, where community transmission is relatively high. In all regions, a combination of low classroom occupancy and robust test-and-trace measures were in place. Our findings underscore the need for a cautious evaluation of reopening strategies. This article is part of the theme issue ‘Modelling that shaped the early COVID-19 pandemic response in the UK’

    Shock wave lithotripsy, for the treatment of kidney stones, results in changes to routine blood tests and novel biomarkers: a prospective clinical pilot-study

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    The number of patients undergoing shock wave lithotripsy (SWL) for kidney stones is increasing annually, and as such the development of post-operative complications, such as haematuria and acute kidney injury (AKI) following SWL, is likely to increase. The aim of the study was to evaluate changes in routine blood and novel biomarkers following SWL, for the treatment of kidney stones. Methods: Twelve patients undergoing SWL for solitary unilateral kidney stones were recruited. From patients (8 males and 4 females) aged between 31 and 72 years (median 43 years), venous blood samples were collected pre-operatively (baseline), at 30, 120 and 240 min post-operatively. Routine blood tests were performed using a Sysmex XE-5000, and Beckman Coulter AU5800 and AU680 analysers. NGAL, IL-18, IL-6, TNF-α, IL-10 and IL-8 concentrations were determined using commercially available ELISA kits. Results: Significant (p ≤ 0.05) changes were observed in several blood parameters following SWL. NGAL concentration significantly increased, with values peaking at 30 min post-treatment (p = 0.033). Although IL-18 concentration increased, these changes were not significant (p = 0.116). IL-6 revealed a statistically significant rise from pre-operative up to 4 h post-operatively (p 0.05). Conclusions: Changes to routine blood tests and specific biomarkers, in the future, may be more useful for clinicians. In turn, identification of a panel of biomarkers could provide valuable data on “normal” physiological response after lithotripsy. Ultimately, studies could be expanded to identify or predict those patients at increased risk of developing post-operative complications, such as acute kidney injury or. These studies, however, need validating involving larger cohorts

    VRIA: A Web-based Framework for Creating Immersive Analytics Experiences

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    We present, a Web-based framework for creating Immersive Analytics (IA) experiences in Virtual Reality.is built upon WebVR, A-Frame, React and D3.js, and offers a visualization creation workflow which enables users, of different levels of expertise, to rapidly develop Immersive Analytics experiences for the Web. The use of these open-standards Web-based technologies allows us to implement VR experiences in a browser and offers strong synergies with popular visualization libraries, through the HTMLDocument Object Model (DOM). This makesubiquitous and platform-independent. Moreover, by using WebVR’s progressive enhancement, the experiencescreates are accessible on a plethora of devices. We elaborate on our motivation for focusing on open-standards Web technologies, present thecreation workflow and detail the underlying mechanics of our framework. We also report on techniques and optimizations necessary for implementing Immersive Analytics experiences on the Web, discuss scalability implications of our framework, and present a series of use case applications to demonstrate the various features of . Finally, we discuss current limitations of our framework, the lessons learned from its development, and outline further extensions

    Cultural Antecedents of Sustainability and Regional Economic Development - A Study of SME ‘Mittelstand’ Firms in Baden-Württemberg (Germany)

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    This is an Accepted Manuscript of an article published by Taylor & Francis in Entrepreneurship and Regional Development on 20/01/2020, available online: https://doi.org/10.1080/08985626.2020.1713223This paper examines behavioural and regional/geographic cultural antecedents of sustainability in SME contexts. The study identifies prevailing macro-representations of sustainability in the literature and highlights an over-focus on large firms constituting the predominant unit of analysis. Moreover, there is a propensity in the literature to view sustainability primarily in terms of ‘environmental’ – closely linked to a corporate strategic imperative narrative of economic competitiveness and profitability. Overall, this perspective tends to generate accounts which are acultural, apolitical and ahistorical in terms of innovative actions and sustainability practices. In response, using a conceptual framework of moral identity, the paper develops a more micro-foundational insight to sustainability (developing notions of ‘tangible’ and ‘intangible’) and examines regional economic development attitudes at individual owner-manager/ managing director level in small-to-medium-sized firms. Methodologically, an inductively framed interview schedule was employed with owner-managers and managing directors (n = 30) of manufacturing SMEs in the Baden-Württemberg region (Germany). The study identified a range of micro-foundational behavioural antecedents operating in the sample companies. In particular, it underlined that many of the SME owner-managers/managing directors expressed views informed by a particular moral identity connected with a perspective rooted in regionally bound, longstanding and ‘expected’ behaviours of trust, fairness, honesty and community responsibility

    Remembering and Forgetting: The Holocaust in 21st Century Britain

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    This article explores the politics of Holocaust memorialization by examining the intersection of education, commemoration and national identity in 21st -century Britain since the inaugural Holocaust Memorial Day in 2001. The article shows how institutionalized spheres have intersected with contemporary cultural discourse surrounding questions of civic morality, immigration and the memory of other genocides. The main argument put forward is that the way in which the Holocaust has been indelibly associated with these issues has both implicitly and explicitly connected Holocaust discourse to contemporary debates on what constitutes British identity in the 21st century. The article also suggests that highly domesticated narratives of the period are often used to promote a self-congratulatory notion of British identity and supposed British exceptionalism

    Gradient-based optimization method for producing a contoured beam with single-fed reflector antenna

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    © 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.A gradient-based optimization method for producing a contoured beam by using a single-fed reflector antenna is presented. First, a quick and accurate pattern approximation formula based on physical optics (PO) is adopted to calculate the gradients of the directivity with respect to reflector's nodal displacements. Because the approximation formula is a linear function of nodal displacements, the gradient can be easily derived. Then, the method of the steepest descent is adopted, and an optimization iteration procedure is proposed. The iteration procedure includes two loops: an inner loop and an outer loop. In the inner loop, the gradient and pattern are calculated by matrix operation, which is very fast by using the pre-calculated data in the outer loop. In the outer loop, the ideal terms used in the inner loop to calculate the gradient and pattern are updated, and the real pattern is calculated by the PO method. Due to the high approximation accuracy, when the outer loop is performed once, the inner loop can be performed many times, which will save much time because the integration is replaced by matrix operation. In the end, a contoured beam covering the continental United States (CONUS) is designed, and simulation results show the effectiveness of the proposed algorithm

    Trapped in discourse? Obstacles to meaningful social work education, research and practice within the neoliberal university

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    This is an Accepted Manuscript of an article published by Taylor & Francis in Social Work Education on 18/12/2019, available online: https://www.tandfonline.com/doi/full/10.1080/02615479.2019.1703933.This article appraises the role of the neoliberal university in regulating social work education, research and practice. The dominance of governments and employers in determining social work education is highlighted, alongside the ascendancy of skills-based and vocational training. Moreover, it is proposed that research, associated learning, and practice are now more often moulded around essentialist science-based, behavioural or functionalist paradigms, which fit conveniently with free market, politically conservative and authoritarian agendas. The neoliberal university is increasingly able to rationally prepare social workers to fulfil narrow ideological objectives, which includes priority given to attempts to empower, pathologise, and scientifically manage structurally disadvantaged populations from minority groups. Reductive paradigms, nevertheless, can struggle to cope with social fragmentation and diversity, with social work students often ill prepared for many of the complex challenges which they later face as qualified practitioners. Analysis for the article draws from critical theory, and it is concluded that market-based discourses and related professional paradigms - and the symbolically constituted and hyperreal fantasies which they help to maintain - can prove difficult to escape. Social work continues to face a precarious future within university settings in which free market narratives, associated norms, targets, and labour insecurity prevail

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