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Teaching the Lesson
No full textThis is an Accepted Manuscript of a book chapter published by Routledge/CRC Press in [Mentoring Mathematics Teachers in the Secondary School: A Practical Guide] on [01/12/2023], available online: https://www.routledge.com/Mentoring-Mathematics-Teachers-in-the-Secondary-School-A-Practical-Guide/Archer-Morgan-Swanson-Clemmet-Sullivan/p/book/9780367361358In this book chapter, the role of the mentor working with beginning teachers is discussed, as they teach their first mathematics lessons. Primarily we will consider how to support the beginning teacher with a structured and collaborative start to their classroom experience and how to allow them to explore different approaches to teaching and designing mathematics lessons. Supporting early teaching experiences involve planning the lesson, managing the emotional and practical aspects of the classroom and helping the beginning teacher to reflect on their teaching and the learning of students in order to use the experience constructively. The development of a range of pedagogical approaches, such as ways of building on prior knowledge, modelling and explaining mathematical ideas, providing feedback, supporting struggling students and asking questions that prompt students to think about mathematics also need to be considered. Initially, beginning teachers can be very concerned about whether they can respond to unforeseen events, including how they gain and maintain the students’ trust and cooperation. These features are addressed in this chapter
Glaziers' Hollow, Delamere Forest, Cheshire: investigation and survey of a late medieval glassworking site
Get PDFArchaeological survey and geophysical survey report.In 2023, a gradiometer survey was conducted over two small areas of a medieval glassworking site known as Glaziers’ Hollow in Delamere Forest primarily to help identify the precise location of excavations conducted there in 1935 and 1947. This survey forms part of a larger project aimed at furthering the understanding of this scheduled monument in response to its current presence on the Historic England Heritage at Risk register. Over two days in June and another two days in November, a small team conducted the gradiometry survey alongside a suite of other non-invasive survey techniques. Results showed a focused cluster of magnetic anomalies that corresponded closely to previously unrecorded earthworks visible on the ground, as well as more modern disturbances and anomalies likely to be the location of the historic excavations. The signature of the readings is somewhat inconclusive as to the specific identification of a glassworking furnace or furnaces, but do suggest glassworking and associated activity close by, although results may be influenced by the amount of disturbance and potential overburden at the site.Report contributors: B. Fitzpatrick, A. Foster, K. Dale, C. Lawton-Lay, J. Nichols, and M. Hawort
Retinol-binding protein 4 (RBP4) circulating levels and gestational diabetes mellitus: a systematic review and meta-analysis
Get PDFBackground: Gestational diabetes mellitus (GDM) is a prevalent condition where diabetes is diagnosed during pregnancy, affecting both maternal and fetal outcomes. Retinol-binding protein 4 (RBP4) is a circulating adipokine which belongs to the lipocalin family and acts as a specific carrier protein that delivers retinol (vitamin A) from the liver to the peripheral tissues. Growing data indicate that circulating RBP4 levels may positively correlate with GDM. Thus, this systematic review and meta-analysis aimed to investigate the potential relationship between circulating RBP4 levels and GDM when measured at various stages of pregnancy. Methods: MEDLINE, CINAHL, EMCARE, EMBASE, Scopus, and Web of Science databases were searched to identify studies comparing pregnant women with and without GDM, whose circulating RBP4 levels were measured in at least one pregnancy trimester. Findings were reported using standardized mean difference (SMD) and random-effects models were used to account for variability among studies. Furthermore, the risk of bias was assessed using the RoBANS tool. Results: Out of the 34 studies identified, 32 were included in the meta-analysis (seven with circulating RBP4 levels measured in the first trimester, 19 at 24–28 weeks, and 14 at >28 weeks of pregnancy). RBP4 levels were statistically higher in the GDM group than in controls when measured during all these pregnancy stages, with the noted RBP4 SMD being 0.322 in the first trimester (95% CI: 0.126–0.517; p 28 weeks of gestation (95% CI: 0.252–1.498; p = 0.006; 870 GDM cases vs. 1942 non-GDM controls). Significant study heterogeneity was noted for all three pregnancy timepoints. Conclusion: The present findings indicate consistently higher circulating RBP4 levels in GDM cases compared to non-GDM controls, suggesting the potential relevance of RBP4 as a biomarker for GDM. However, the documented substantial study heterogeneity, alongside imprecision in effect estimates, underscores the need for further research and standardization of measurement methods to elucidate whether RBP4 can be utilized in clinical practice as a potential GDM biomarker. Systematic review registration: PROSPERO (CRD42022340097: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022340097).Acknowledgements: We would like to thank the University Hospitals Coventry and Warwickshire (UHCW) NHS Trust for the ongoing support
The perspective of current and retired world class, elite and national athletes on the inclusion and eligibility of transgender athletes in elite sport
Get PDFThere has been limited empirical study allowing athletes to voice their opinions on transgender participation in elite sport. This study surveyed 175 national, elite and world class athletes eligible to compete in the female category regarding transgender inclusion and eligibility. The study compared current Olympic versus current Olympic Recognised sports, elite versus world class, and current versus retired Olympic sport athletes. Most athletes favoured biological sex categorisation (58%) and considered it unfair for trans women to compete in the female category, except for precision sports. This view was held most strongly by world class athletes regarding their own sport (77% unfair, 15% fair). For trans men inclusion in the male category, most athletes considered it fair, except for Olympic sport athletes regarding contact sports (49% unfair, 27% fair) and sports heavily reliant on physical capacity (53% unfair, 29% fair). Notwithstanding those views, athletes (81%) believed sporting bodies should improve inclusivity for transgender athletes. Opinion varied somewhat according to career stage, competitive level and sport type. Nevertheless, athletes in the present study favoured categorisation by biological sex and did not support trans women eligibility for the female category in sports reliant on performance-related biological factors that differ between sexes
Real-world clinical and psychosocial outcomes among people with mild or moderate haemophilia A treated on-demand in the Italian CHESS II cohort: a real-world data analysis
Get PDF© 2024 Giancarlo Castaman et al., published by SciendoBackground: The burden of severe haemophilia A (HA) has been studied extensively owing to the higher bleeding frequency and associated treatment requirements, leaving a clear unmet need for research focused on the burden of mild and moderate HA. Aims: This study sought to characterise the clinical and psychosocial burden of mild and moderate HA in the Italian cohort of the CHESS II study. Methods: This was a retrospective analysis of clinical and psychosocial outcomes in a cohort of male adults (≥18 years old) with mild or moderate HA who participated in the cross-sectional CHESS II study (October 2019-November 2020). Treatment patterns, acute and chronic clinical outcomes and mental health indicators were collected via physician-completed forms. Psychosocial outcomes related to impact of HA on social activities, exercise, opportunities, and lifestyle were collected via a participant self-complete questionnaire. All results were reported descriptively. Results: A total of 113 people with haemophilia A (PwHA) were included, 79 (70%) with moderate HA and 34 (30%) with mild HA, with mean age of 41.4 and 36.6 years, respectively. No one in the sample was receiving a prophylaxis at the time of data capture, with factor VIII use in the 12 months prior reported in 30% and 29% of moderate and mild PwHA, respectively. Ninety-one PwHA (81%) experienced ≥1 bleeding event in the preceding 12 months. People with moderate HA had higher mean annual bleed rate (2.9 vs. 1.1, respectively) and higher prevalence of chronic pain (74% vs. 35%), anxiety (20% vs. 12%), and/or depression (15% vs. 3%). Target joints were reported in 22% and 12% of moderate and mild PwHA, and problem joints in 51% and 12%, respectively. Of 113 participants, 44 (39%) completed the self-complete form (moderate HA, 57%; mild HA, 43%). Overall, 40% vs. 10% of those with moderate vs mild HA reported reducing or giving up social activities, 44% vs. 21% reducing or giving up exercise, 36% vs. 26% missing out on opportunities, and 48% vs. 26% reported HA impacted their lifestyle. Conclusion: Moderate PwHA from the Italian CHESS II cohort appeared to have greater clinical morbidity and lifestyle impact than mild PwHA. Psychosocial outcomes were also worse among moderate PwHA, but significant burden was also observed among mild PwHA. These findings, and the absence of prophylactic treatment in the sample examined, highlight that improving management for potentially undertreated mild/moderate PwHA may aid the avoidance long-term clinical morbidity and negative psychosocial impact.Acknowledgements: This paper reports a retrospective study in which no human participants or animals are directly involved. Medical writing/editorial support was provided by Jeff Frimpter, MPH, funded by HCD Economics. This analysis was funded by Roche SpA, Rozzano, Italy. Roche were involved in the analysis conception, design and interpretation of results, as well as drafting and submission of the manuscript. EFG, TB1, and TB2 are employees of HCD Economics. LS, RT and SB are employees of Roche SpA
Tessier [other name Ross], Isabella Emily Louisa [pseud. Marie Duval, Ambrose Clarke] (1847–1890)
Get PDFBiography of Isabel Emilie de Tessier (Marie Duval and others)
Caring Work
Get PDF12 'tablescapes' in colour tell a personal story of 12 Oxford Hospitals Trust staff working in the areas of Cleaning, Catering, Portering and Estates across the four Trust hospitals (John Radcliffe Hospital, Churchill Hospital, Nuffield Orthopaedic Centre and Horton General Hospital, Oxford). Derived from individual and group conversations, these include stories of offering or receiving help from other staff, other carers or patients, reflections and realisations had in quiet moments, or at the busiest times of day and anecdotes of creative problem-solving or the use of humour as care. These stories demonstrate the ways in which the work of support staff in the Trust is the work of caring – for patients, the communities of staff and themselves. Together, they contributed to "Our National Health: Hospital Stories", responding to the national 'prompts and provocations' offered by Kwame Kwei Arma, in the creation of a new performance. The 12 drawings are permanently installed as 12 printed vinyl table-top in cafes across the four hospital sites.Oxford Hospitals Charit
Non-alcoholic fatty liver disease and coexisting depression, anxiety and/or stress in adults: a systematic review and meta-analysis
Get PDFCopyright © 2024 Shea, Lionis, Kite, Lagojda, Uthman, Dallaway, Atkinson, Chaggar, Randeva and Kyrou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.Background: Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease, affecting 25-30% of the general population globally. The condition is even more prevalent in individuals with obesity and is frequently linked to the metabolic syndrome. Given the known associations between the metabolic syndrome and common mental health issues, it is likely that such a relationship also exists between NAFLD and mental health problems. However, studies in this field remain limited. Accordingly, the aim of this systematic review and meta-analysis was to explore the prevalence of one or more common mental health conditions (i.e., depression, anxiety, and/or stress) in adults with NAFLD. Methods: PubMed, EBSCOhost, ProQuest, Ovid, Web of Science, and Scopus were searched in order to identify studies reporting the prevalence of depression, anxiety, and/or stress among adults with NAFLD. A random-effects model was utilized to calculate the pooled prevalence and confidence intervals for depression, anxiety and stress. Results: In total, 31 studies were eligible for inclusion, involving 2,126,593 adults with NAFLD. Meta-analyses yielded a pooled prevalence of 26.3% (95% CI: 19.2 to 34) for depression, 37.2% (95% CI: 21.6 to 54.3%) for anxiety, and 51.4% (95% CI: 5.5 to 95.8%) for stress among adults with NAFLD. Conclusion: The present findings suggest a high prevalence of mental health morbidity among adults with NAFLD. Given the related public health impact, this finding should prompt further research to investigate such associations and elucidate potential associations between NAFLD and mental health morbidity, exploring potential shared underlying pathophysiologic mechanisms. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42021288934.Acknowledgements: SS, IK, and HR would like to thank the University Hospitals Coventry and Warwickshire (UHCW) NHS Trust and the General Charities of Coventry for their ongoing support
Numerical Approximation for a Stochastic Fractional Differential Equation Driven by Integrated Multiplicative Noise
Get PDFWe consider a numerical approximation for stochastic fractional differential equations driven by integrated multiplicative noise. The fractional derivative is in the Caputo sense with the fractional order α∈(0,1), and the non-linear terms satisfy the global Lipschitz conditions. We first approximate the noise with the piecewise constant function to obtain the regularized stochastic fractional differential equation. By applying Minkowski’s inequality for double integrals, we establish that the error between the exact solution and the solution of the regularized problem has an order of O(Δtα) in the mean square norm, where Δt denotes the step size. To validate our theoretical conclusions, numerical examples are presented, demonstrating the consistency of the numerical results with the established theory
Pandora's Box (2009)
No full textPublishing information and table of contents for issue 7 (2009)Founded 2003, Pandora’s Box is an annual literary periodical publishing a selection of the year’s best creative writing by students and staff at the University of Chester.N/
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