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Pectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia-reperfusion injury in rats.
No full textWe investigated whether the feeding of high H2-generating dietary fibre and resistant starch (RS) could suppress hepatic ischaemia-reperfusion (IR) injury, which results from oxidative stress, in rats fed a pectin (Pec) or high-amylose maize starch (HAS) diet. Male Sprague-Dawley rats were fed a control (C) diet, with or without Pec (0-5 % Pec) or HAS (0-30 % HAS) supplementation for 7 d. Portal H2 concentration showed a significant dose-dependent increase with the amount of Pec or HAS supplementation. Plasma alanine and aspartate aminotransferase activities remarkably increased in the C rats (5 % cellulose) due to IR treatment, while it decreased significantly or showed tendencies to decrease in 5 % Pec and 20 % HAS diet-fed rats. The hepatic oxidised glutathione (GSSG):total glutathione ratio increased significantly in IR rats maintained on the C diet compared with sham-operated rats. On the other hand, reduced glutathione (GSH):total glutathione and GSH:GSSG ratios decreased significantly. The GSSG:total glutathione ratio that increased due to IR treatment decreased significantly on HAS and Pec intake, while GSH:total glutathione and GSH:GSSG ratios increased significantly. Hepatic sinusoids of IR rats fed the C diet were occluded, but those of IR rats fed the Pec diet were similar to those in the sham-operated rats. In conclusion, we found that Pec or HAS, which enhance H2 generation in the large intestine, alleviated hepatic IR injury. The present study demonstrates another physiological significance of dietary fibre and RS.We investigated whether the feeding of high H2-generating dietary fibre and resistant starch (RS) could suppress hepatic ischaemia-reperfusion (IR) injury, which results from oxidative stress, in rats fed a pectin (Pec) or high-amylose maize starch (HAS) diet. Male Sprague-Dawley rats were fed a control (C) diet, with or without Pec (0-5 % Pec) or HAS (0-30 % HAS) supplementation for 7 d. Portal H2 concentration showed a significant dose-dependent increase with the amount of Pec or HAS supplementation. Plasma alanine and aspartate aminotransferase activities remarkably increased in the C rats (5 % cellulose) due to IR treatment, while it decreased significantly or showed tendencies to decrease in 5 % Pec and 20 % HAS diet-fed rats. The hepatic oxidised glutathione (GSSG):total glutathione ratio increased significantly in IR rats maintained on the C diet compared with sham-operated rats. On the other hand, reduced glutathione (GSH):total glutathione and GSH:GSSG ratios decreased significantly. The GSSG:total glutathione ratio that increased due to IR treatment decreased significantly on HAS and Pec intake, while GSH:total glutathione and GSH:GSSG ratios increased significantly. Hepatic sinusoids of IR rats fed the C diet were occluded, but those of IR rats fed the Pec diet were similar to those in the sham-operated rats. In conclusion, we found that Pec or HAS, which enhance H2 generation in the large intestine, alleviated hepatic IR injury. The present study demonstrates another physiological significance of dietary fibre and RS.journal articl
産学連携地域シンポジウム : 地域資源の掘り起こしと産業化の取り組み ～第六次産業化による地域の活性化をめざして～
No full text110009432819departmental bulletin pape
「児童虐待防止法」（法律第四十號）について －わが国のこどもの権利思想と法成立の背景一考－
Get PDF40019237894applidation/pdfdepartmental bulletin pape
Parents' Feelings Regarding Attending Their Children's Treatment －Comparison of Parental Feelings when Children Undergo Blood Collection or Receive an Injection－
No full text110009428344application/pdf本研究の目的は,子どもの処置に付き添った場合と付き添わなかった場合での両場面に対する親の思いと各場面における親の思いを比較し,親のニーズを捉えた対応を検討することである。両場面の経験をもつ親を対象に自作の自記式質問紙により2010 年6 〜 8 月に,処置の付き添いに対する親の希望や思いに関する調査を実施した。その結果,付き添いに対する親の意向は「希望する」6 割,「希望しない」1 割,「どちらともいえない」3 割であった。思いの比較では,処置に付き添った時の方が安心感や医療者への信頼感は強く,付き添わない方が不安は強く子どもをよりかわいそうに感じることが示された。また,親も子どもの処置に参加する権利を求めており,子どもと親の意向を必ず聞いて欲しいという意見が示され,子どもと親のニーズに即したケアや思いを尊重する関わりの重要性を認識することにつながった。The objective of this study was to compare parents' feelings in regard to being present or not when theirchildren undergo minor medical procedures in order to ascertain how to meet parents' needs. The survey involvedparents who had experience of being both present and not present during these procedures and was carried out betweenJune and August 2010 using our unique self-completion questionnaire. The survey was designed to investigate parents'wishes and feelings regarding accompanying their children during treatment. The results showed that 60% of parents"wished to attend treatment", 10% "did not wish to attend treatment," and 30% were "undecided." The comparison offeelings revealed that the parents had a higher sense of reassurance and trust for healthcare professionals if theyattended treatment, whereas parents felt more anxiety and sorrier for their children if they did not attend treatment. Inaddition, parents wished to have the right to be present during the treatment of their children and commented thathealthcare professionals should always ask children and parents what they wanted. These results underlined theimportance of the care meeting the needs of children and parents, and the relationship respecting the feelings of them.departmental bulletin pape
21世紀の知識基盤社会へ向けた新たな高等学校の部活動システム
No full text知識基盤社会とは何か。これからの学校教育に求められることは何か。そして部活動（スポーツ）には何が求められているのか。
本研究は、21世紀の知識基盤社会へ向けた新たな部活動像を検討することであり、次の観点で論じた。21世紀とはどのような時代を迎えているのか、文部科学省が見据える社会を史観的に検討した（第３章）。我が国がこれまで学校教育で教示してきた知識について考察した（第４章）。先行研究の事例を概観しながら「知識基盤社会」が求める21世紀の新たな部活動システムを検証した（第５章）。
これまでの形式化された伝統的な部活動システムから脱却し、創造性豊かなシステム構築が今後は期待されてくるであろう。21世紀の我が国の学校は、生徒たちの溢れる可能性と創造性を覚醒させるための新たな部活動システムを再考すべき時にあるようだ。journal articl
