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Ohl 122, no. 99 – An apotropaic tablet with a curse against those who desecrate churches, with a reference to Jews, reign of Justinian, ca. 6th century CE
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Innovative Design & Performance Assessment of a Novel Modular Reactor for One-Step Liquid Fuel Production from Stranded Natural Gas
No full textPoster Division: Engineering: 1st Place (The Ohio State University Edward F. Hayes Advanced Research Forum)The crude extraction process faces a challenge in tackling the associated natural gas that is dissolved in the crude oil or prevails in the free gas caps of oil reservoirs. Considering the risks and costs involved in natural gas transportation, the quantity of associated gas is very small to substantiate the construction of a pipeline network. Although this associated natural gas is the by-product of the oil extraction process, the absence of a viable solution for utilization makes it ‘stranded natural gas (SNG).’ Approximately 15 tons/day of SNG is flared from one oil well, contributing to greenhouse gases. The uneconomical nature of pipeline installation to transport SNG and the necessity to find a robust solution to tackle SNG opens an avenue for developing modular technologies that can convert SNG to value-added products while reducing CO2 emissions. Liquid fuels (LF) are high-density energy carriers that are easy to transport and can support the existing infrastructure for energy consumption. 15 tons/day of SNG that is flared has the potential to produce ~2.5 tons/day of LF and generate ~115 kW of electricity simultaneously. This work proposes a single reactor modular unit that converts SNG to value-added LF. The novel reactor configuration consists of a multi-tubular packed bed setup divided into three intermediate sections: a mixed reforming section, a section for heat exchange, and a Fischer-Tropsch (FT) section. Mixed reforming of SNG uses CO2 and steam to produce high-quality syngas (H2:CO = 1.7), which in turn can be used to produce liquid fuels in the FT section of the reactor. The heat exchange section assists in increasing the efficiency of the process by facilitating heat integration within the process streams. This process provides inherent CO2 utilization and converts pressurized SNG to easy-to-transport liquid fuels that can be processed to manufacture motor spirit, diesel, jet engine fuels, and feedstocks for the petrochemical industry. System-level thermodynamic evaluation was conducted using ASPEN Plus software for the production of 2.5 tons/day of liquid fuel by taking into consideration multiple plausible cases of reactor configuration and heat integration. Detailed economic calculations performed based on the tubular reactor design for all configurations indicate that the production of liquid fuels using SNG can prove to be a profitable venture. The design of the multi-tubular reactor and the economics associated with it are simultaneously optimized using the Bayesian optimization technique to propose a portable, modular reactor requiring a minimum number of units to process the SNG from an oil well. The robustness of the best-case scenario is then validated for fluctuating SNG compositions, flow rates, and temperatures. This work establishes the design feasibility of a novel, economically viable, modular technology for upgrading SNG to value-added liquid fuels while reducing greenhouse gas emissions.A five-year embargo was granted for this item
Using HLA-E Expression and CREB1 Modulation to Study the Regulation of NK Cell-Mediated Cytotoxicity in Multiple Myeloma
Get PDFMultiple myeloma (MM) develops in the bone marrow from normal plasma cells, reshaping the bone marrow microenvironment to survive. Several MM treatments, such as immunomodulatory drugs and proteasome inhibitors, are available as therapeutic options for patients; however, MM remains largely incurable. While patients undergoing treatment may notice improvement in their symptoms, many patients still experience relapse. For that reason, personalized therapeutic options that consider genetic and environmental factors may facilitate improved patient health outcomes. While the immune system’s surveillance is equipped with the necessary mechanisms to ward off infections and diseases, cancer cells have novel ways to evade detection. The innate immune system utilizes natural killer (NK) cells to prevent the spread of viruses and growth of tumor cells. NK cells display both activating and inhibitory receptors in which, upon ligand interaction, leads to downstream signaling to elicit the proper cellular response. HLA-E, a non-classical major histocompatibility complex, is a ligand that binds to the NKG2A/CD94 inhibitory surface receptor on NK cells where it can regulate cell-mediated cytotoxicity. In healthy cells, HLA-E functions to prevent NK cell-mediated cytotoxicity upon interaction as a means of recognizing “self” cells from aberrant cells. However, as our study emphasizes, MM cells express abnormally high amounts of HLA-E to bypass the immune system and escape NK cell-mediated lysis. Our study aims to investigate immune escape via modulation of the HLA-E antigen both at the mRNA and protein level through IFN-gamma expression, proteins involved in the JAK-STAT pathway, and the CREB1 gene wherein inhibition of CREB1 has demonstrated downregulation in HLA-E and consequently restored NK cell-mediated lysis.No embargoAcademic Major: BiologyAcademic Major: Biochemistr
Interpersonal Relationships within Muslim Communities in Franklin County
Get PDFThis study was created to understand intimate partner violence (IPV) among Muslim individuals living in the Franklin County, Ohio. The study focused on three objectives, knowledge of IPV, prevalence of IPV, and knowledge of IPV resources. Eligibility requirements for the study were that participants had to be 18 or older, self-identify as Muslim, and reside in the Franklin County. Participants were recruited primarily via flyers and through social media and Muslim community listservs. A total of 40 participants completed an online survey via Qualtrics. Overall, average knowledge of IPV was low with participants scoring 13 on average out of a total of 25. Prevalence IPV perpetration ranged from 2% to 5%, and prevalence of IPV victimization ranged from 2% to 5%. When it comes to utilization of local resources, more participants indicated they would utilize or suggest Health Care/ Mental Health/Counseling, and Imam services (35%) followed by Emergency Medical, Police, Crisis hotline/advocate/support services (32.5%) then Shelter services (25%), and lastly by pursuing restraining orders (22.5%) . For perceived access to these services, more participants indicted that they would find an Imam (35%) in their neighborhood, followed by Police (27.5%), followed by Restraining order (22.5%), Emergency Medical Services (22.5%), Mental Health Counselor/Therapist (22.5%), followed by Health Care Provider (17.5%) or Crisis Hotline/Advocate/Support, and Shelter Services (10%). The majority of participants also indicated islamophobia and lack of knowledge about local resources create barriers to accessing IPV related resources. This study provides early evidence for the need for interventions in which the community can have further conversations on the topic of IPV, increase knowledge of IPV, and create a more supportive community when IPV experiences occur.No embargoAcademic Major: Social Wor
An Evaluation of the Accuracy of Numerical Weather Prediction for a Summer Antarctic Severe Storm
Get PDFSecond place, Earth & Beyond, 2024 Denman Undergraduate Research ForumModern weather forecasting relies on the Numerical Weather Prediction (NWP) models that have been produced from extensive research and evaluation. Work continues to be done to increase the accuracy of these models all around the world so forecasters can deliver accurate predictions of future weather events. The Antarctic is a much different environment than more populated areas such as North America and Europe. The geography, dynamic effects, and regionally specific phenomena make predicting storms in and around the Antarctic much more difficult. The Drake Passage region has become a popular destination for ship-based ecotourism. The purpose of this research is to analyze the accuracy of the ECMWF and GFS operational global models to see how well they predicted a severe storm that resulted in the loss of life. Using data from 26 November – 1 December 2022, these models are evaluated to determine how far in advance they can accurately predict the storm. Based on statistical analysis performed on the two forecast models (and one reanalysis dataset), a five day period performed to an acceptable degree of accuracy that should allow enough time for a forecaster to accurately predict the threat of a storm in the Drake Passage. The ECMWF and GFS operational models provide enough accuracy for operators in the Antarctic to safely plan all operations. Forecasts for some stations do not perform to a high accuracy; in this case a method is discussed in detail that can be used to increase forecast accuracy.National Science Foundation for the Year of Polar Prediction - Southern Hemisphere (NSF Grant No. 2205398)Scientific Committee on Antarctic Research (SCAR) Physical Sciences GroupNo embargoAcademic Major: Atmospheric Science
Dance Education Put into Practice: An Argument and Plan for a Dance Educator Teaching Corps
No full textA sociological examination of the importance of dance education in public schools, followed by a business plan for the creation of a dance educator corps.Arts Undergraduate Research ScholarshipNo embargoAcademic Major: Danc
