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    13197 research outputs found

    ソーシャル センサ ノ パフォーマンス ト イチ ジョウホウ ニ カンスル ケンキュウ

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    奈良先端科学技術大学院大学修士(工学)master thesi

    プログラミング ショキュウシャ オ タイショウ ト シタ エラー シュウセイ ジカン ノ ブンセキ

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    奈良先端科学技術大学院大学修士(工学)master thesi

    ゲンゴ セイセイ モデル ニ ヨル ビョウメイ ノ ヨミ ト ICD-10 コード スイテイ

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    奈良先端科学技術大学院大学修士(工学)master thesi

    サンカガタ センシング ニ オケル カイトウ シンライセイ コウジョウ ノ タメ ノ タチバ ヒョウメイ シュホウ

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    奈良先端科学技術大学院大学修士(工学)master thesi

    シロイヌナズナ MYB イデンシ ニ オケル ミツセン ノ ハッセイ セイギョ キコウ ノ カイメイ

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    奈良先端科学技術大学院大学修士(バイオサイエンス)master thesi

    Exploring the use of text-based image generation for creative writing

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    奈良先端科学技術大学院大学博士(工学)doctoral thesi

    A Trust Model with Personality Factors for Information Dissemination in Social Networking Service

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    奈良先端科学技術大学院大学博士(工学)doctoral thesi

    Adhesion-clutch between DCC and netrin-1 mediates netrin-1$2013induced axonal haptotaxis

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    The growth cone, a motile structure located at the tip of growing axons, senses extracellular guidance cues and translates them into directional forces that drive axon outgrowth and guidance. Axon guidance directed by chemical cues on the extracellular adhesive substrate is termed haptotaxis. Recent studies reported that netrin-1 on the substrate functions as a haptotactic axon guidance cue. However, the mechanism mediating netrin-12013inducedaxonalhaptotaxisremainsunclear.Here,wedemonstratethatsubstrateboundnetrin1inducesaxonalhaptotaxisbyfacilitatingphysicalinteractionsbetweenthenetrin1receptor,DCC,andtheadhesivesubstrates.DCCservesasanadhesionreceptorfornetrin1.Theclutchlinkermoleculeshootin1ainteractedwithDCC,linkingittoactinfilamentretrogradeflowatthegrowthcone.SpeckleimaginganalysesshowedthatDCCunderwenteithergrip(stop)orretrogradeslipontheadhesivesubstrate.Thegripstatewasmoreprevalentonnetrin12013induced axonal haptotaxis remains unclear. Here, we demonstrate that substrate-bound netrin-1 induces axonal haptotaxis by facilitating physical interactions between the netrin-1 receptor, DCC, and the adhesive substrates. DCC serves as an adhesion receptor for netrin-1. The clutch-linker molecule shootin1a interacted with DCC, linking it to actin filament retrograde flow at the growth cone. Speckle imaging analyses showed that DCC underwent either grip (stop) or retrograde slip on the adhesive substrate. The grip state was more prevalent on netrin-12013coated substrate compared to the control substrate polylysine, thereby transmitting larger traction force on the netrin-12013coatedsubstrate.Furthermore,disruptionofthelinkagebetweenactinfilamentretrogradeflowandDCCbyshootin1knockoutimpairednetrin12013coated substrate. Furthermore, disruption of the linkage between actin filament retrograde flow and DCC by shootin1 knockout impaired netrin-12013induced axonal haptotaxis. These results suggest that the directional force for netrin-1$2013induced haptotaxis is exerted on the substrates through the adhesion-clutch between DCC and netrin-1 which occurs asymmetrically within the growth cone.journal articl

    Is Silent External Human$2013Machine Interface (eHMI) Enough? A Passenger-Centric Study on Effective eHMI for Autonomous Personal Mobility Vehicles in the Field

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    Autonomous personal mobility vehicle (APMV) is a miniaturized autonomous vehicle designed for short-distance mobility to everyone. Due to its open design, APMV’s passengers are exposed to communications between the external human-machine interface (eHMI) on APMV and pedestrians. Therefore, effective eHMI designs for APMV need to consider potential impacts of APMV-pedestrian interactions on passengers’ subjective feelings. This study from the perspective of APMV passengers discussed three eHMI designs: (1) graphical user interface (GUI)-based eHMI with text message (eHMI-T), (2) multimodal user interface (MUI)-based eHMI with neutral voice (eHMI-NV), and (3) MUI-based eHMI with affective voice (eHMI-AV). In a riding field experiment (N2009=2009=200924), eHMI-T made passengers feel awkward during the “silent time” when eHMI-T conveyed information exclusively to pedestrians, not passengers. MUI-based eHMIs with voice cues showed advantages, with eHMI-NV excelling in pragmatic quality and eHMI-AV in hedonic quality. Considering passengers’ personalities and genders in APMV eHMI design is also highlighted.journal articl

    Subjective Vertical Conflict Model With Visual Vertical: Predicting Motion Sickness on Autonomous Personal Mobility Vehicles

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    Passengers of level 3$20135 autonomous personal mobility vehicles (APMV) can perform non-driving tasks, such as reading books and smartphones, while driving. It has been pointed out that such activities may increase motion sickness, especially when frequently avoiding pedestrians or obstacles in shared spaces. Many studies have been conducted to build countermeasures, of which various computational motion sickness models have been developed. Among them, models based on subjective vertical conflict (SVC) theory, which describes vertical changes in direction sensed by human sensory organs v.s. those expected by the central nervous system, have been actively developed. To model motion sickness due to conflict between visual vertical information and vestibular sensation, we proposed a 6 DoF SVC-VV model which added a visually perceived vertical block into a conventional 6 DoF SVC model to predict visual vertical directions from image data simulating the visual input of a human. In a driving experiment, 27 participants rode on the APMV and experienced slalom driving with two visual conditions: looking ahead (LAD) and working with a tablet device (WAD). We verified that passengers got motion sickness while riding the APMV, and the symptoms were severer when especially working on it, by simulating the frequent pedestrian avoidance scenarios of the APMV in the experiment. In addition, the results of the experiment demonstrated that the proposed 6 DoF SVC-VV model could describe the increased motion sickness experienced when the visual vertical and gravitational acceleration directions were different.journal articl

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