13197 research outputs found
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Federated Financial Security: Towards Robust & Resilient Detection of Dynamic Cyberthreats
Full text link奈良先端科学技術大学院大学博士（工学）doctoral thesi
Structural basis of substrate recognition by SecDF driving protein translocation across the membrane
Full text link奈良先端科学技術大学院大学博士（バイオサイエンス）doctoral thesi
Learning Context-Aware Gaze Behavior in Virtual Reality: An Evaluation of an LLM-Driven Conversational Agent Training System
Full text link奈良先端科学技術大学院大学修士（工学）master thesi
SUPPRESOR OF GAMMA RESPONSE 1 promotes early onset of endoreplication upon DNA double-strand breaks by inducing CCS52A1 expression in Arabidopsis roots
No full textLiving organisms are constantly at the risk of DNA damage caused by factors such as DNA replication errors, reactive oxygen species, and UV radiation. In plants, DNA damage activates the NAC-type transcription factor SUPPRESSOR OF GAMMA RESPONSE 1 (SOG1) that governs DNA damage responses such as cell cycle arrest, stem cell death, and early onset of endoreplication. However, molecular mechanisms underlying the early induction of endoreplication onset in response to DNA damage remain elusive. In this study, we show that CELL CYCLE SWITCH 52 A1 (CCS52A1), an activator of the APC/C E3 ligase, plays a major role in the early onset of endoreplication in response to DNA double-strand breaks (DSBs) in Arabidopsis roots. Upon DSBs, SOG1 directly binds to the CCS52A1 locus, thereby inducing its expression. Moreover, early transition to endoreplication in response to DSBs is suppressed in ccs52a1 knockout roots. Our data propose that increased polyploidy may function as a unique adaptative mechanism to genotoxic stress in plants.journal articl
Optimizing non-assisted body part movements for robot-assisted therapy
No full textLearning to control muscles in movement is essential in rehabilitation. The use of biofeedback and robotics to induce muscle activity has been investigated in recent years. The human musculoskeletal system has complex inter-limb interactions, which have been simplified in previous studies by immobilizing non-assisted body parts. This study proposes a framework to induce the desired muscle activity pattern and provide visual feedback to the user by optimizing the reference trajectory of the non-assisted body part in robotic rehabilitation. In the proposed framework, an individual model learning and trajectory optimization method was utilized to consider the constraints of the rehabilitation time slot. Its performance was verified through experiments on 12 healthy subjects. The results show improved effectiveness and feasibility, achieved by reducing the discrepancies between targeted and induced muscle activations, compared to the baseline, which did not optimize non-assisted body part movements.journal articl
Refractive epitrochoids sampling for light field measurement using wedge prisms
Full text linkConventional light field measurement using a micro-lens array suffers from grid-like artifacts in the refocused image because the sub-aperture images are sampled at linear and equal intervals like a grid pattern. In this study, we propose a method for measuring light field using a pair of wedge prisms and a method for calibrating the sub-aperture position. The epitrochoids trajectory of rays generated by rotating prisms yields unequal intervals and variable sampling of the sub-aperture position. We designed and calibrated the optical system, and verified the effectiveness of the proposed method on refocused images using the measured light field.journal articl
Energy Efficient CGRA Accelerators for Cryptography and Medical Image Diagnosis
Full text link奈良先端科学技術大学院大学博士（工学）doctoral thesi
Shootin1b ト N-cadherin ノ ソウゴ サヨウ オ カイシタ シンケイ サイボウ イドウ キコウ ノ カイセキ
Full text link奈良先端科学技術大学院大学博士（ﾊﾞｲｵｻｲｴﾝｽ）doctoral thesi