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Miniaturized Cell Fluorescence Imaging Device Equipped with Multielectrode Array
No full textIn this study, a fabrication method for a system composed of a fluorescence imaging module and a multielectrode array (MEA) chamber is described. It is important to measure both fluorescence intensity and electrical activity to obtain a better understanding of a physiological activity, such as spikes or action potentials, of cells. However, observing these physiological traits long-term with cultured cells is difficult using a conventional microscope. In this study, we developed a small fluorescence imaging device with an MEA that can be used in a conventional CO2 incubator. The fluorescence imaging module was composed of a CMOS image sensor, a fiber-optic plate (FOP), a blue LED, and optical filters. The FOP enabled the device to be miniaturized through lensless fluorescence imaging. The MEA chamber was fabricated with micro gold electrodes deposited on the FOP. By using the FOP for the bottom of the chamber, we measured both the fluorescence signal and electrophysiology signal in the same experiment. The performance of the device was evaluated with neuronal blastoma cells. Our device enabled us to observe fluorescence images and MEA signals.research repor
SASIMI: Evaluation Board for EM Information Leakage from Large Scale Cryptographic Circuits
Get PDFIn this paper, we propose a common evaluation board(Side-channel Attack Standard IMplementation and eval-uatIon board: SASIMI) for the threat of acquiring information leaked from electromagnetic(EM) noise generated by devices. To prevent this threat, it is necessary to implement circuits that do not leak secret information, like a secret key, via EM side-channel, and conduct actual measurement and evaluation environment, which makes it difficult for a third party to reproduce the results. However, since captured EM activity is affected by the surrounding EM noise, the evaluation results may vary depending on the evaluation environment. The proposed evaluation board can implement various cryp-tographic circuits. The IC must be capable of reconfiguring logic and implementing large-scale cryptographic blocks such as post quantum cryptography. To reduce the influence of environmental EM noise, an independent power supply network and measurement port are provided for the IC to be evaluated thus improving the measurement reproducibility. In order to evaluate the performance of the SASIMI board, this paper proposes an index to evaluate the strength of the information of the secret key contained in the power supply noise. This index is to find the value of the resistance to be inserted into the power supply network of the prototype board. Measurement results show that the simple amplitude value of EM noise and the intensity of information leakage do not necessarily coincide.conference pape
Guidance of Axon Outgrowth Activated by Femtosecond Laser Processing in a Microfluidic Device
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Structural functionalization of polysilsesquioxane for thin-film device applications
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Post-modification of poly(trimethylene carbonate) derivatives with ester free type and their physical and biological properties
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Efficient Implementations of Neural Network Powered by Spike Coding and Scalable Bisection Spanning
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The Role of ACC2 in Tumorigenesis: From Acute Myeloid Leukemia to Solid Tumors
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Application of CMOS-based Devices for Dual-site Fluorescent Imaging of Pain Processing Brain Regions
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アニマシー チカク オ モチイタ ナイブ ジョウタイ ノ AR テイジ ガ カデン シヨウジ ノ フカイカン ト コウドウ ニ アタエル エイキョウ
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