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東海国立大学機構学術デジタルアーカイブの取り組み：文理融合研究を支えるデジタルアーカイブの挑戦
Get PDF第27回図書館総合展 (2025年10月22日~24日、パシフィコ横浜) の発表ポスターconference outpu
Contextualisation of Lesson Study in Mongolia: Cultural Script of Teaching and Teachers’ Responses to Students’ Mistakes
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Phase Transition of MnN2 Associated with N2 Dimer Alignment under High Pressure and High Temperature
No full textManganese pernitride (MnN2) was synthesized at a pressure of approximately 60 GPa and a temperature of approximately 2000 K for the first time. A phase transition between rhombohedral and triclinic symmetry associated with the alignment of the N2 dimer was also clearly observed at high temperatures under high pressure or along the decompression process at room temperature. The present experimental results with DFT calculations offer new insights and diversity into the crystal chemistry of the transition metal pernitrides concerning temperature and pressure.journal articl
Triple oxygen isotope evidence for the pathway of nitrous oxide production in a forested soil with increased emission on rainy days
Get PDFContinuous increases in atmospheric nitrous oxide (N2O) concentrations are a global concern. Both nitrification and denitrification are the major pathways of N2O production in soil, one of the most important sources of tropospheric N2O. The 17O excess (Δ17O) of N2O can be a promising signature for identifying the main pathway of N2O production in soil. However, reports on Δ17O are limited. Thus, we determined temporal variations in the Δ17O of N2O emitted from forested soil for more than one year and that of soil nitrite (NO2^-), which is a possible source of O atoms in N2O. We found that N2O emitted from the soil exhibited significantly higher Δ17O values on rainy days (+0.12 ± 0.13 ‰) than on fine days (−0.30 ± 0.09 ‰), and the emission flux of N2O was significantly higher on rainy days (38.8 ± 28.0 µg N m−2 h−1) than on fine days (3.8 ± 3.1 µg N m−2 h−1). Because the Δ17O values of N2O emitted on rainy and fine days were close to those of soil NO2^- (+0.23 ± 0.12 ‰) and O2 (−0.44 ‰), we concluded that although nitrification was the main pathway of N2O production in the soil on fine days, denitrification became active on rainy days, resulting in a significant increase in the emission flux of N2O. This study reveals that the main pathway of N2O production can be identified by precisely determining the Δ17O values of N2O emission from soil and by comparing the Δ17O values with those of NO2^-, O2, and H2O in the soil.journal articl
The frozen elephant trunk technique
Get PDFThe frozen elephant trunk (FET) technique, which was an advanced version of the elephant trunk technique, is now the gold standard for distal aortic arch repair. The major advantage is that the distal anastomosis is fixed by the stent; therefore, anastomosis that has been used to be performed in the descending aorta can be performed on the more proximal side of the aortic arch. The FET technique has become widely used, causing the increased risk of spinal cord injury (SCI) to become a major concern. As the FET fixes the distal side, the risk of SCI increases depending on its landing zone and depth. To avoid SCI, stent length should be limited to about 10 cm, and the use stents of 15 cm in length or landing beyond Th8 should be avoided. Another problem after the FET technique is the distal site new entry (d-SINE) in the mid- and long-term stages. d-SINE can also occur after thoracic endovascular aortic repair (TEVAR), mainly due to its oversizing. The spring-back-force, which is also related to the stent strength, is also said to be a cause of d-SINE after the FET technique. I herein review the FET technique, its surgical outcomes, and complications.departmental bulletin pape
Acupuncture alleviates the progression of knee osteoarthritis by inhibiting X-inactive specific transcript-mediated activation of the mechanosensitive ion channel Piezo1 signaling
Get PDFAcupuncture (AP) has been widely used in the treatment of knee osteoarthritis (KOA); however, its underlying molecular mechanisms remain elusive. This study aimed to identify whether acupuncture can relieve KOA progress via inhibiting X-inactive specific transcript (XIST)-mediated Piezo1 activation. The OA cells treated by interleukin (IL)-1β, and rat OA models induced by monosodium iodoacetate were established respectively. The expression of XIST, Piezo1, and extracellular matrix (ECM)-degeneration proteins were evaluated. Cell proliferation was detected by Cell Counting Kit-8 assay. The binding interaction between XIST and Piezo1 was performed using RNA binding protein immunoprecipitation assay (RIP). When XIST is knocked down, apoptosis is significantly reduced, and CHON-001 cell proliferation is increased in comparison to control and IL-1β-induced chondrocytes. Function tests revealed that both in vitro and in vivo, siRNA targeting XIST (si-XIST) increased cell proliferation while preventing apoptosis, ECM degradation, and the production of inflammatory factors. Additionally, we demonstrated that XIST and Piezo1 were bound together via insulin-like growth factor 2 messenger RNA (mRNA) binding proteins 2 (IGF2BP2), with Piezo1 serving as XIST’s target. The effects of XIST downregulation were reversed by Piezo1 activation via rescue tests conducted both in vitro and in vivo. Piezo1’s expression was reversed after XIST knockdown by IGF2BP2 overexpression. Our findings highlight the therapeutic potential of acupuncture in mitigating the progression of KOA by targeting the XIST-mediated activation of the Piezo1 pathway. By inhibiting this pathway, acupuncture may offer a promising approach to ameliorate the symptoms and slow the progression of KOA.departmental bulletin pape
Factors related to physical violence and verbal abuse by residents for public health nurses during home visits
Get PDFRecently, customer harassment has attracted considerable attention in various professional fields. Home visits are the basis of public health nurses’ activities, but there are few reports on customer harassment during home visits. This study clarified the current situation and factors related to verbal abuse and physical violence experienced from residents during public health nurses’ home visits. Data were collected from 80 individuals through a mailed survey of 154 public health nurses employed at 17 health centers in Gifu Prefecture. The survey utilized anonymous and self-administered questionnaires (response rate, 51.9%). The analysis showed that 80.0% of the participants had experienced the verbal abuse by residents during home visits, and 16.3% had experienced the physical violence. Result of logistic analysis, those who had experienced verbal abuse were approximately 10 times more likely to experience physical violence (adjusted odds ratio [AOR]=9.95; 95% confidence interval [CI]=2.49–39.79). Additionally, it was suggested that a factor associated with verbal abuse was “the number of months from starting work until visiting alone.” In contrast, factors associated with physical violence included “total years of experience as a public health nurse,” “highest level of education,” “qualifications,” “type of work,” and “experience outside of public health center or health center.”departmental bulletin pape
A 12-week cycling program improves glucose homeostasis, lipid profile, and body composition in women with insulin resistance: a pilot study
Get PDFThis study evaluated the effects of a cycling intervention on glucose homeostasis, lipid profile, and body composition in individuals with insulin resistance and excess body weight. Seven women participants completed a 12-week supervised cycling program (20–30 min/day, 3 days/wk). Body composition assessments and biochemical analyses, including oral glucose tolerance tests, triglycerides, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and non-high-density lipoproteins, were conducted pre- and post-intervention. Paired t-tests and Hedge's g assessed changes in body composition, lipid profile, and homeostatic model assessment for insulin resistance (HOMA-IR), while a 2×4 repeated-measures analyses of variance (ANOVA) analyzed exercise- and time-related effects on glucose and insulin. Post-intervention, significant moderate reductions were observed in body fat mass (p = 0.020, g = −0.52), body fat percentage (p = 0.006, g = −0.55), visceral fat area (p = 0.005, g = −0.64), and waist-to-hip ratio (p < 0.001, g = −0.87). A significant, small reduction in non-high-density lipoproteins was also noted (p = 0.016, g = −0.34). A 2×4 repeated-measures ANOVA revealed a significant effect of exercise on glucose concentration (p = 0.031; η2p = 0.640, moderate), with lower post-exercise levels. Additionally, a significant time×exercise interaction was observed for insulin concentration (p = 0.009; η2p = 0.30, moderate). Follow-up tests comparing pre to post-exercise changes revealed significant decreases in insulin levels at 30-min (p < 0.001), 60-min (p = 0.008), and 120-min (p = 0.011) postload. These findings suggest a 12-week cycling intervention improves glucose homeostasis, lipid profile, and body composition in overweight women with insulin resistance.departmental bulletin pape