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慢性血栓塞栓性肺高血圧症患者におけるバルーン肺動脈拡張術前後の肺灌流血液量CT、肺灌流SPECTおよびカテーテル肺血管造影画像の比較による臨床および予測的価値
No full text長崎大学学位論文 [学位記番号]博（医歯薬）甲第1289号 [学位授与年月日]令和2年12月2
パフォーマンスステータス2/3のプラチナ抵抗性尿路上皮癌患者における4週毎の低用量ゲムシタビン・パクリタキセル治療
Get PDF長崎大学学位論文 学位記番号:博(医歯薬)甲第1217号 学位授与年月日:令和2年3月19
淡明腎細胞癌におけるCD57+細胞、CD68+細胞、および肥満細胞の細胞密度と比率の病理学的意義と予後的役割
Get PDF長崎大学学位論文 [学位記番号]博（医歯薬）甲第1218号 [学位授与年月日]令和2年3月19
生理学的薬物速度論を用いたキニンとリトナビル/ロピナビルの合剤を同時投与する時の適切量の同定
Get PDF長崎大学学位論文 [学位記番号]博（医歯薬）甲第1238号 [学位授与年月日]令和2年3月19
軸圧縮を受ける溶接箱形断面柱の耐荷力に対する初期たわみの定量的影響に関する数値解析とその定式化
No full text長崎大学学位論文 [学位記番号]博（工）甲第80号 [学位授与年月日]令和2年3月19
Study on prevention of hypercapnia by nasal high flow in patients undergoing endoscopic retrograde cholangiopancreatography during intravenous anesthesia
Get PDFBACKGROUND: For relatively invasive upper gastrointestinal endoscopy procedures, such as an endoscopic retrograde cholangiopancreatography (ERCP), and also lower gastrointestinal endoscopy procedures, intravenous anesthesia is routinely used to reduce patient anxiety. However, with the use of intravenous anesthesia, even at mild to moderate depth of anesthesia, there is always a risk of upper airway obstruction due to a relaxation of the upper airway muscles.With the advent of nasal high flow (NHF) devices that allow humidified high flow air through the nasal cavity, can be used as a respiratory management method in the context of anesthesia. AIRVO is commonly used for patients with obstructive sleep apnea and other respiratory disorders. This device uses a mild positive pressure load (several cmH2O) that improves carbon dioxide (CO2) washout and reduces rebreathing to improve respiratory function and therefore is widely used to prevent hypoxemia and hypercapnia.This study aims to maintain upper airway patency by applying NHF with air (AIRVO) as a respiratory management method during intravenous anesthesia for patients undergoing an ERCP. In addition, this study investigates whether the use of an NHF device in this context can prevent intraoperative hypercapnia and hypoxemia. METHODS/DESIGN: This study design employed 2 groups of subjects. Both received intravenous anesthesia while undergoing an ERCP, and 1 group also used a concurrent nasal cannula NHF device. Here we examine if the use of an NHF device during intravenous anesthesia can prevent hypoxemia and hypercapnia, which could translate to improved anesthesia management.Efficacy endpoints were assessed using a transcutaneous CO2 monitor (TCM). This device measured the changes in CO2 concentration during treatment. Transcutaneous CO2 (PtcCO2) concentrations of 60 mm Hg or more (PaCO2 > 55 mm Hg) were considered marked hypercapnia. PtcCO2 concentrations of 50 to 60 mm Hg or more (equivalent to PaCO2 > 45 mm Hg) were considered moderate hypercapnia.Furthermore, the incidence of hypoxemia with a transcutaneous oxygen saturation value of 90% or less, and whether the use of NHF was effective in preventing this adverse clinical event were evaluated. DISCUSSION: The purpose of this study was to obtain evidence for the utility of NHF as a potential therapeutic device for patients undergoing an ERCP under sedation, assessed by determining if the incidence rates of hypercapnia and hypoxemia decreased in the NHF device group, compared to the control group that did not use this device. TRIAL REGISTRATION: The study was registered in the jRCTs 072190021.URL https://jrct.niph.go.jp/en-latest-detail/jRCTs072190021
Predation of a large orb-web spider by a crab spider, Thomisus labefactus (Araenae: Thomisidae)
Get PDFIn the present study, I reported that the female adult crab spider Thomisus labefactus preyed on a female adult of the wasp spider Argiope bruennichi in the centre of the web. To my knowledge, the case that a large orb-weaving spider A. bruennichi is fed upon by the crab spiders with web-invading is not known previously. It has been shown that T. labefactus, considered commonly as a sit-and-wait predator, also aggressively hunt A. bruennichi, the large web-building spider, attacking its prey at the centre of web
Factors Associated With Parental Readiness Amongst Japanese Female Undergraduate Nursing Students: A Cross-Sectional Study
Get PDFBackground: Trends towards a nuclear family unit, a decline in birth rate, and lack of community relationships make it difficult for adolescents to improve parental readiness in Japanese society. Low parenting skills will be a risk factor for high parenting stress or child abuse. The purpose of the present study is to investigate the factors associated with parental readiness amongst Japanese female undergraduate nursing students. Methods: The study design is cross-sectional. An anonymous self-reported questionnaire survey was distributed to 225 female undergraduate nursing students from Kyushu, Japan, and the factors associated with parental readiness were examined. Results: Of the 225 recipients, 208 responded to the questionnaire. Multiple linear regression analysis showed that the parental readiness score was significantly higher in the following groups: students who lived alone or without parents (regression coefficient: β = 1.82, p = .027), students who often interacted with children (β = 1.88, p = .018), students who wanted to give birth (β = 5.72, p = .007), and students who wanted to rear children as their own parents did (β = 2.73, p = .009). Conclusions: The factors associated with parental readiness were living without parents, experiences interacting with children, desire to give birth, and desire to rear children as their own parents did