Mehmet Akif Ersoy University

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    2779 research outputs found

    Strong Statistical Convergence in Probabilistic Metric Spaces

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    In this article, we introduce the concepts of strongly statistically convergent sequence and strong statistically Cauchy sequence in a probabilistic metric (PM) space endowed with the strong topology, and establish some basic facts. Next, we define the strong statistical limit points and the strong statistical cluster points of a sequence in this space and investigate the relations between these concepts

    Immunodetection of Thyroid Hormone Receptor (Alpha1/Alpha2) in the Rat Uterus and Oviduct

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    Thyroid hormones (THs) play an important role in reproduction and are essential for development in vertebrate species. It has been reported that hypothyroidism in women causes irregular menstruation, frank infertility and difficulty in maintaining pregnancy [10], and hypothyroidism in rodents induces alterations in the estrous cycle and uterine morphology [13]. It has been reported that thyroidectomy causes a decrease in basal plasma levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH) [8, 28]. Thyroid hormone receptors (THR) mediate the cellular response to thyroid hormone (T3) by regulating target gene transcription. THR are the products of two different genes, erbAá and erbAâ. The mammalian erbAá gene produces two mRNAs, erbAá1 (alpha1) and erbAá2 (alpha2). Alpha1 codes for the alpha-thyroid hormone receptor (TRá1), whereas alpha2 codes for an orphan nuclear receptor (TRá2) which does not bind T3. TRá2 competes with TRá1 and TRâ for specific DNA binding sites, thereby antagonizing T3 action. Because the erbAá gene produces both a transcriptional activator (TRá1) and its specific inhibitor (TRá2), regulation of the alternative processing of alpha1 and alpha2 mRNA may provide an important mechanism for determining the cellular response to THs [12]. In the present study, we have immunohistochemically investigated the existence and localization of THR (alpha1/ alpha2) in rat uterus and oviduct

    Ankara’da Etçi ve Sütçü Sığırlarda Kuyruk Ucu Nekrozu: Ankara’da 7 Olgunun Sunumu

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    Kuyruk ucu nekrozu uzun yıllardır sert zeminli ahırlarda bakılan sığırlarda meydana gelen bir hastalık olarak bilinmektedir. Hastalık etçi yönlü yetiştirilen düvelerde, inek ve boğalarda bildirilmiştir. Bu makalede yazarlar Ankara ilinde toplam yedi etçi ve sütçü sığırda makroskopik olarak gözlemlenen kuyruk ucu nekrozunu tanımlamaktadırlar. Kuyruk ucu nekrozunun tanısı klinik muayene ve makroskopik olarak gözlemlenen lezyonların tanımlayıcı analizleri ile konulmuştur. Bu makale ile kuyruğuda içeren iskelet-kas sistemi hastalıklarının ayırıcı tanısında, kuyruk ucu nekrozunun öneminin vurgulanması amaçlanmaktadır.Tail-tip necrosis has long been recognized as a disease condition occurring in cattle housed on slattedfloors. The disease has been reported in heifers, steers and bulls with beef production. In the present article the authors describe macroscopically diagnosed tail-tip necrosis in a total of seven beef and dairy cattle observed in Ankara. Diagnosis of tail tip necrosis was made on the basis of clinical examination and descriptive analysis of gross lesions. The present article highlights the importance of including tail-tip necrosis on the list of differential diagnoses for diseases characterized by involvement of the musculoskeletal system, consisting of the tail

    GENERALISED TUBERCULOSIS IN A CAT

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    Clinical, pathomorphological and immunohistological findings of generalised tuberculosis diagnosed in a 1-year-old male tabby cat were evaluated. Macroscopic examination revealed greyish-white nodules, exceeding the surface of the organ, in the meninges and kidneys. The meninges nodules were of the size of a pinhead and those in the kidneys were 0.2-0.5 cm in diameter. The mediastinal lymph nodes were observed to be enlarged, and their cut surfaces displayed nodules of a similar appearance and size. Microscopic examination revealed typical tubercles in the cerebrum, cerebellum, kidneys, and mediastinal lymph nodes. The presence of Mycobacterium tuberculosis either free or located within the cytoplasm of macrophages was demonstrated by means of the avidin-biotin complex peroxidase method

    Treatment of Trichomoniasis with Metronidazole and Oxytetracycline Combination in Pigeons

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    Bu çalışmada Ankara Üniversitesi Veteriner Fakültesi İç Hastalıklar Anabilim Dalı Kliniğine hasta şikayeti ile 2005 Mayıs’ta getirilen 6 yavru güvercin ve 2007 Ocak’ta getirilen 4 yavru güvercin olmak üzere Ankara’daki iki farklı yetiştiriciliğe ait toplam 10 güvercin incelendi. Yavru güvercinlerin klinik muayenesinde hırıltılı solunum, ağzı kapamada güçlük, halsizlik, konha ve farinkste bej renkte nekrotik lezyonlar belirlendi. Yetiştiriciliklere yapılan ziyarette kafes zeminlerinin toprak tabanlı olduğu ve hijyenik şartlara uygun olmadığı dikkati çekti. Kontrollerde birinci yetiştiricilikteki barınakta bulunan 10 yavrunun tamamının, diğer yetiştiricilikteki 9 yavrunun klinik bulgu gösterdiği erişkinlerde ise hastalık tablosunun bulunmadığı dikkati çekti. Hasta 10 genç güvercinin konha ve farinks bölgelerindeki nekrotik lezyonlardan alınan kazıntı materyalinin mikroskobik muayenesinde hareketli trichomonas etkenleri görüldü. Sağaltımda metronidazol ve oksitetrasiklin kombinasyonu uygulandı. Güvercinlerin bulunduğu kafesler %4’lük sodyum hidroksitli suyla yıkatıldı. Sağaltımın ikinci gününde yavrulardan durumu ağır olan 2’si ölürken, sekizinde sağaltımın yedinci gününden itibaren hastalığa ilişkin klinik bulguların ortadan kalktığı gözlendi ve bu güvercinlerden alınan konha ve farinks küretaj materyallerinin mikroskobik muayenesinde trichomonas etkenine rastlanmadı. Sonuç olarak hayvan sahiplerinin ifadelerine göre yetiştiriciliklerde önceki yıllarda sağaltım uygulamalarına rağmen ortaya çıkan ölüm oranları ile bu dönemdeki ölüm oranı karşılaştırıldığında metronidazol ve oksitetrasiklin kombinasyonunun sağaltımda etkili olduğu söylenebilir

    Presence and characteristics of sorbitol-negative Escherichia coli O157 in healthy sheep faeces

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    The presence of sorbitol-negative Escherichia coli O157 was investigated in healthy Awassi sheep faeces from 175 randomly selected animals in Burdur province of Turkey. Out of 175 animals, 16 (9.1%) were faecal shedding of sorbitol-negative E. coli O157. Out of the 15 flocks included in the study, 7 (47%) had at least one sheep positive for sorbitol-negative E. coli O157. The isolation rate of sorbitol-negative E. coli O157 ranged from 8.3 to 60% among the animals tested in the flocks. A total of 16 ovine sorbitol-negative E. coli O157 strains were characterized by a multiplex PCR. Results showed that 6 (37.7%) strains carried stx1 gene, 3 (18.8%) stx2 gene and 1 (6.3%) both stx1 and stx2 genes. Intimin (eaeA) gene was detected in 4 (25%) of the strains. None of the strains encoding for stx genes was positive for eaeA gene. The results demonstrate that the majority of sorbitol-negative E. coli O157 strains (62.5%) isolated from Awassi sheep in Burdur province of Turkey are Shiga toxin-producing E. coli that have a potential as human pathogens

    ÜÇ SÜTÇÜ İNEKTE ENZOOTİK BOVINE LÖKOZİS (EBL) ENFEKSİYONUNUN KLİNİK, SEROLOJİK, HEMATOLOJİK ve PATOLOJİK OLARAK İNCELENMESİ

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    Bu çalışmada, 3 yaşında Holstein ırkı üç inekte Enzootik Bovine Lökozis (EBL) enfeksiyonu klinik, serolojik, hematol ojik ve patolojik yönden incelendi. Klinik inceleme lerde hayvanla rda aşırı kilo kaybı, iştahsızl ık, özellikle preskapular lenf düğümünde belirgin olmak üzere tüm yüzlek lenf düğümlerinde büyüme, aralıklı yüksek ateş, kalp aritmisi, düzensiz solunum ve inkoordinasyon geliştiği tespit edildi. Bu klinik görünüme sahip üç inekte yapılan serolojik testlerde [Agar Jel Immunodiffuzyon (AGID) ve Enzim Linked Immunosorbent Assay (ELISA)] Bovine Lökozis Virus (BLV)’una karşı antikor varlığı belirlendi. Seropozitif tespit edilen üç inekte, hematolojik muayenelerde B-lenfosit, total lökosit ve total lenfosit oranlarında artışlar ve T-lenfosit, null hücreleri ve nötrofil oranlarında azalmalar görüldü. Hayvanların kesimleri sonrasında yapılan patolojik muayenelerde bütün lenf düğümler inde lenfadenopati dikkati çekti. Özellikle yüzlek lenf düğümle rinde korteks medulla ayrımının yapılamadığı ve kanamaların bulunduğu görüldü

    ISOLATION AND ANTIBIOTIC SUSCEPTIBILITY OF AEROMONAS HYDROPHILA IN A CARP (CYPRINUS CARPIO) HATCHERY FARM

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    The aim of this study was to describe a case of skin lesions with haemorrhaging in a carp (Cyprinus carpio) hatchery farm and to determine effective antibiotic treatments. In the macroscopic examinations of nine carp with haemorrhagic skin lesions, brown or red spotted skin changes of a varying degree were found, along their bodies. No lesions were observed in the internal organs. Pure cultures of Aeromonas hydrophila were isolated from the skin, kidney, heart, and liver of the carp. All of the isolates were found to be susceptible to danofloxacin, enrofloxacin, gentamicin, ciprofloxacin, neomycin, and trimethoprim-sulphamethoxazole and resistant to ampicillin, amoxicillin, amoxicillin/clavulanic acid, oxytetracycline, and streptomycin. Treatment of A. hydrophila infection was carried out by applying trimethoprim-sulphamethoxazole for 3 d at 10 g/ton of pool water

    Conservation status of freshwater mussels in Europe: state of the art and future challenges

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    Freshwater mussels of the Order Unionida provide important ecosystem functions and services, yet many of their populations are in decline. We comprehensively review the status of the 16 currently recognized species in Europe, collating for the first time their life-history traits, distribution, conservation status, habitat preferences, and main threats in order to suggest future management actions. In northern, central, and eastern Europe, a relatively homogeneous species composition is found in most basins. In southern Europe, despite the lower species richness, spatially restricted species make these basins a high conservation priority. Information on freshwater mussels in Europe is unevenly distributed with considerable differences in data quality and quantity among countries and species. To make conservation more effective in the future, we suggest greater international cooperation using standardized protocols and methods to monitor and manage European freshwater mussel diversity. Such an approach will not only help conserve this vulnerable group but also, through the protection of these important organisms, will offer wider benefits to freshwater ecosystems

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