University of Münster
Münstersches Informations und Archivsystem für Multimediale InhalteNot a member yet
10543 research outputs found
Sort by
Annual Report 2024/2025
No full textDer Jahresbericht des Käte Hamburger Kollegs "Einheit und Vielfalt im Recht" an der Universität Münster berichtet über Aktivitäten, Fellows, Forschungsthemen, Veranstaltungen und Publikationen in den Jahren 2024/2025.The annual report of the Käte Hamburger Kolleg "Legal Unity and Pluralism" at the University of Münster provides information on activites, fellows, research topics, events, and publications in 2024/2025
Net Present Value with Zero and Negative Interest Rates
No full textDer Kapitalwert lässt sich auch bei Null- und Negativzinsen zumindest über endliche Zeiträume einfach berechnen sowie betriebswirtschaftlich für Investitionsentscheidungen sinnvoll verwenden. Volkswirtschaftlich ist relevant, warum es Zinsen von und unter null überhaupt gibt und ob höherer Konsum dann nicht besser wäre als ressourcenverbrauchende Investitionen.Even with zero and negative interest rates, the net present value can be easily calculated, at least over finite periods of time, and used for investment decisions by companies. Economically, it is relevant why there are interest rates of and below zero at all and whether higher consumption would then not be better than resource-consuming investments
Molecular and functional characterisation of the phosphatidylethanolamine-binding protein (PEBP)-family in Dioscorea polystachya with special emphasis on the tuber-inducing properties of DpFT-like3
No full textYams (Dioscorea ssp.) sind Knollenpflanzen, die vornehmlich in tropischen und sub-tropischen Gebieten abgebaut werden. Trotz kommerzieller Relevanz ist über die Knollenentwicklung in Yams wenig bekannt.
In der Entwicklung von Speicherorganen von Kartoffeln und Zwiebeln spielt das Protein FLOWERING LOCUS T (FT), Teil der phosphatidyletanolamine-binding protein Familie (PEBP), eine Rolle.
In dieser Dissertation wurde die PEBP-Familie, insbesondere FT in der chinesischen Yam (Dioscorea polystachya) untersucht.
Insgesamt wurden 17 verschiedene PEBPs identifiziert, von denen neun der FT-Untergruppe zugeordnet werden konnten.
Sequenz- und Expressionsanalysen führten zur Auswahl von DpFT-like3 als Kandidat für weitere Untersuchungen.
Überexpressionsstudien von DpFT-like3 in A. thaliana und S. tuberosum deuten auf eine induzierende Rolle von DpFT-like3 in der Knollenbildung in der chinesischen Yam hin.Yams (Dioscorea ssp.) are tuberous plants, mainly grown in tropical and sub-tropical regions. Despite their commercial relevance, few informations are published about the molecular development of their tubers.
The protein FLOWERING LOCUS T (FT), member of the phosphatidyletanolamine-binding protein family (PEBP), plays a role in the development of storage organs of potato and onion.
In this dissertation, the PEBP-family, especially the FT-subclade, was investigated in Chinese Yam (Dioscorea polystachya).
Overall, 17 different PEBPs, nine of which belonged to the FT-subclade, were identified.
Sequence- and expressionanalyses led to the selection of DpFT-like3 as a candidate for further investigation.
Overexpression of DpFT-like3 in A. thaliana and S. tuberosum indicate a potential inducing role of DpFT-like3 in the tuber development of Chinese yam
Patients' perspectives on the use of artificial intelligence in dentistry: a regional survey
No full textThe use of artificial intelligence (AI) in dentistry is rapidly evolving and could play a major role in a variety of dental fields. This study assessed patients’ perceptions and expectations regarding AI use in dentistry. An 18-item questionnaire survey focused on demographics, expectancy, accountability, trust, interaction, advantages and disadvantages was responded to by 330 patients; 265 completed questionnaires were included in this study. Frequencies and differences between age groups were analysed using a two-sided chi-squared or Fisher’s exact tests with Monte Carlo approximation. Patients’ perceived top three disadvantages of AI use in dentistry were (1) the impact on workforce needs (37.7%), (2) new challenges on doctor–patient relationships (36.2%) and (3) increased dental care costs (31.7%). Major expected advantages were improved diagnostic confidence (60.8%), time reduction (48.3%) and more personalised and evidencebased disease management (43.0%). Most patients expected AI to be part of the dental workflow in 1–5 (42.3%) or 5–10 (46.8%) years. Older patients (> 35 years) expected higher AI performance standards than younger patients (18–35 years) (p < 0.05). Overall, patients showed a positive attitude towards AI in dentistry. Understanding patients’ perceptions may allow professionals to shape AI-driven dentistry in the future
Causal Hierarchy in the Financial Market Network—Uncovered by the Helmholtz–Hodge–Kodaira Decomposition
No full textGranger causality can uncover the cause-and-effect relationships in financial networks. However, such networks can be convoluted and difficult to interpret, but the Helmholtz–Hodge–Kodaira decomposition can split them into rotational and gradient components which reveal the hierarchy of the Granger causality flow. Using Kenneth French’s business sector return time series, it is revealed that during the COVID crisis, precious metals and pharmaceutical products were causal drivers of the financial network. Moreover, the estimated Granger causality network shows a high connectivity during the crisis, which means that the research presented here can be especially useful for understanding crises in the market better by revealing the dominant drivers of crisis dynamics
Concerto à 4 D-Dur für Traversflöte, Oboe d’amore, Violine und Basso continuo (D-RH Ms 161)
No full textDas Musikleben in den Residenzen Hohenlimburg und Rheda unter Graf Moritz Casimir I. von Bentheim-Tecklenburg (1701-1768) wurde maßgeblich von Johann Martin Doemming (geb. 1703 in Milz/Thüringen, gest. um 1760) geprägt. Über die musikalische Ausbildung des Verwaltungsangestellten Doemming ist nichts bekannt, jedoch muss sie so fundiert gewesen sein, dass er 1731 zum "Directore musices" bestellt wurde. Doemming hat zahlreiche Kompositionen für den Gebrauch der Hofmusik hinterlassen, insbesondere konzertante Musik für Bläser, Streicher und Basso continuo. Unter seiner Leitung wurde 1750 ein thematischer "Catalogus musicus" angelegt, der das Repertoire der Hofkapelle während der Regierungszeit von Moritz Casimir I. widerspiegelt. Die erhaltenen Werke von Johann Martin Doemming sind - vielfach als Autograph - ausschließlich in der Fürstlich zu Bentheim-Tecklenburgischen Musikbibliothek Rheda überliefert
Das dritte Geschlecht im Allgemeinen Gleichbehandlungsgesetz
No full textDie Ausarbeitung untersucht den Geschlechtsbegriff im Allgemeinen Gleichbehandlungsgesetz (AGG) und beginnt mit einer gesetzesinternen Analyse gemäß der subjektiven Theorie. Im Anschluss wird der Begriff systematisch verfassungsrechtlich beleuchtet, insbesondere im Lichte der Entscheidung des Bundesverfassungsgerichts (BVerfG) vom 10.10.2017 (1 BvR 2019/16). Dabei wird das dogmatische Geschlechtsverständnis des BVerfG hermeneutisch hinterfragt und ein Bezug zur US-amerikanischen Verfassungsinterpretation hergestellt. Danach wird der unionsrechtliche Geschlechtsbegriff untersucht, der – ähnlich wie in Art. 3 GG – Gleichberechtigung zwischen Männern und Frauen betont.
Die verfassungsrechtliche Deutung des Geschlechtsbegriffs wird auf das AGG übertragen. Lösungsansätze zur verfassungskonformen Rechtsfortbildung und Praxisfragen wie geschlechtsneutrale Stellenausschreibungen oder Kommunikation im Arbeitsrecht werden erörtert. Abschließend erfolgt eine Gesamtbewertung und ein Ausblick auf das geplante Selbstbestimmungsgesetz, mit Blick auf unionsrechtliche Vorgaben und den Gleichstellungsauftrag nach Art. 3 Abs. 2 GG
Dissociating different temporal stages of emotional word processing by feature-based attention
No full textNegative emotional content is prioritized across different stages of information processing as reflected by different components of the event-related potential (ERP). In this preregistered study (N = 40), we investigated how varying the attentional focus allows us to dissociate the involvement of specific ERP components in the processing of negative and neutral words. Participants had to discriminate the orientation of lines overlaid onto the words, the word type (adjective/noun), or the emotional content (negative/neutral). Thus, attention was either not focused on words (distraction task), non-emotional aspects, or the emotional relevance of words. Regardless of the task, there were no significant differences between negative and neutral words for the P1, N1, or P2 components. In contrast, interactions between emotion and task were observed for the early posterior negativity (EPN) and late positive potential (LPP). EPN differences were absent during the distraction task but were present in the other two tasks. LPP emotion differences were found only when attention was directed to the emotional content of words. Our study adds to the evidence that early ERP components do not reliably separate negative and neutral words. However, results show that mid-latency and late stages of emotion processing are separable by different attention tasks. The EPN represents a stage of attentional enhancement of negative words given sufficient attentional resources. Differential activations during the LPP stage are associated with more elaborative processing of the emotional meaning of words
Psychometric properties and normative values of the revised demoralization scale (DS-II) in a representative sample of the German general population
No full textBackground: Demoralization is a clinically relevant syndrome in chronic diseases. The demoralization scale (DS-II) was recently developed as an economic screening tool in clinical populations. Main aim of this study was to provide normative data of DS-II scores in the general population. Methods: We developed a new German version, the DS-II Münster, and tested internal consistency as well as the previously proposed two-factor structure with confirmatory factor analyses. The DS-II was applied in a household survey of the general population. Associations between DS-II scores and age, gender and other sociodemographic variables were explored. Results: The final sample consisted of N = 2471 participants (mean age = 49.8 years, range: 18–96; 50.1% men, 49.8% women). The DS-II Münster showed nearly excellent internal consistency. The model fit indices of the two-factor structure were not superior to those of the one-factor model. Mean scores of the DS-II were as follows. Total score: M = 3.76 (SD = 5.56), Meaning and Purpose subscale: M = 1.65 (SD = 2.77), Distress and Coping Ability subscale: M = 2.11 (SD = 3.02). DS-II scores were increased in women with an effect size of Cohen’s d = 0.19. An age-related increase was specifically found for the Meaning and Purpose subscale (d = 0.21).
Conclusions: The study provides normative values of the DS-II with respect to age and gender in the general population to facilitate interpretation of DS-II scores in clinical samples. A DS-II total score > 5 is suggested as a cut-off value. The findings further our understanding of significant symptom burden that was previously suggested in young patients with cancer
Reversible photoregulation of cell-cell adhesions with opto-E-cadherin
No full textE-cadherin-based cell-cell adhesions are dynamically and locally regulated in many essential processes, including embryogenesis, wound healing and tissue organization, with dysregulation manifesting as tumorigenesis and metastasis. However, the lack of tools that would provide control of the high spatiotemporal precision observed with E-cadherin adhesions hampers investigation of the underlying mechanisms. Here, we present an optogenetic tool, opto-E-cadherin, that allows reversible control of E-cadherin-mediated cell-cell adhesions with blue light. With opto-E-cadherin, functionally essential calcium binding is photoregulated such that cells expressing opto-E-cadherin at their surface adhere to each other in the dark but not upon illumination. Consequently, opto-E-cadherin provides remote control over multicellular aggregation, E-cadherin-associated intracellular signalling and F-actin organization in 2D and 3D cell cultures. Opto-E-cadherin also allows switching of multicellular behaviour between single and collective cell migration, as well as of cell invasiveness in vitro and in vivo. Overall, opto-E-cadherin is a powerful optogenetic tool capable of controlling cell-cell adhesions at the molecular, cellular and behavioural level that opens up perspectives for the study of dynamics and spatiotemporal control of E-cadherin in biological processes