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Preparation for Workplace Realities: Educating Nursing Students on how to Manage Interruptions
No full textThe Effects of a Tier 1 Self-Regulation Intervention on Elementary Students’ Engagement and Reading Comprehension
No full textAs students’ emotional self-regulation impacts their engagement in learning, as well as their mental health, researchers have called for schools to implement systems of emotional support. However, because school resources are limited, and the demands on teachers’ time continue to grow, identifying emotional self-regulation interventions that teachers can easily implement within their classrooms can be beneficial for student well-being. This study examined the effects of a Tier 1 Self-Regulation Intervention on student engagement and reading comprehension. Within an A-B-A-B-A-B reversal design, a pilot self-regulation intervention was implemented in two classrooms over six weeks. The study’s results indicated that the intervention may have positively impacted student engagement and reading comprehension. Given the study’s positive results, the intervention may be a strategy to support student emotional regulation. Future researchers should consider the benefits of the intervention in larger social and behavioral schoolwide systems, such as MTSS
Social Justice Theatre: Notes From the Field Dramaturgy
Full text linkUnder a dramaturgical lens, I worked to provide the resources and support for responsible and ethical social justice theatre. My research dives into the injustice and oppression depicted in Anna Deavere Smith\u27s play Notes from the Field, which centers around the school-to-prison pipeline in the United States
Modernism’s Mythic Mothers: Queering Motherhood Through Classical Matrilineage
No full textSamantha Lepak\u27s dissertation Modernism\u27s Mythic Mothers: Queering Motherhood Through Classical Matrilineage focuses on the Modernist poet H.D. (Hilda Doolittle) and her rewritings of Greek mythology that center women, particularly mothers. By writing on this mythology’s women, and by being a woman writer herself, H.D. marks a significant deviation from the male-dominated literary traditions surrounding her which designated the classical world as reserved for men. A classical patrilineage is replaced by matrilineage, with this dissertation arguing H.D.’s role as a mythical mother herself while additionally exploring H.D. in relation to queer theory and concepts of temporality
Organizing for Environmental Justice in Chicago\u27s Northside
Full text linkAs one of Loyola’s Social Justice Interns, Aana Shenai worked as an intern with ONE Northside, a community organizing non-profit based in Chicago’s northside. In addition to learning foundational organizing principles, Aana designed a popular training as her internship project that focused on showing community members the intersections between the climate, environment and energy. Her other work included supporting the ONS Green Schools Campaign by attending school research visits, helping schools find funding for green projects, and building relationships with community partners
The Loss of Neuropeptide F Signaling Reduces the Strength of Locomotor Rhythms But Not Feeding Rhythms
Full text linkCircadian rhythms are produced by an organism’s molecular clock, which exists within specific neurons in the brain. Limited information exists on the pathways that connect the clock to downstream neuronal populations controlling behavior. Neuropeptide F (NPF) is a signaling molecule in Drosophila that is linked both to feeding behavior and circadian rhythms, but whether NPF contributes to rhythmic feeding is unknown. NPF and NPFR mutant flies were utilized to assess locomotor activity and feeding rhythms with behavioral assays. We find flies lacking NPF and NPFR display a decrease in locomotor rhythm strength, though there is no effect on feeding rhythms
Sleep, Psychological Symptoms, and Executive Functioning Over the Pubertal Transition in Adolescent Girls
No full textThis study examines the relationship between sleep, mental health, and executive functioning (EF) across the female pubertal transition. Participants (N=49) assigned female at birth completed two lab visits, before and after menarche, to assess anxiety, depression, and EF. Participants wore an actigraph wristwatch to collect sleep data for 7 days. Results showed that participants had later bedtime post-menarche and no significant changes in psychological symptoms or EF. Sleep did not moderate the relationship between premenarchal mental health and post-menarcheal EF. These findings contrast with prior research, highlighting the need for further studies with larger, more diverse samples to better understand these processes
Molecular Dynamic Simulation of the Dissociation of Acetylsalicylic Acid with Different Co-Crystals
No full textAdding co-crystals to a drug is a viable technique used in the field of pharmacology to improve the dissociation of a target drug. In our project, we examined the rate of dissolution of Acetaminophen using molecular dynamic (MD) simulations, and how it varies when different co-crystals are added in. We will specifically be using oxalate and citrate. The goal of this project is to be able to determine how different co-crystals interact with Acetaminophen to be able to predict similar interactions in the future. The results will be useful for pharmaceutical research and drug development
Women’s Mud Cloth Skirt (Bogolanfini)
Full text linkThe Bogolafini mud cloth is made by and for the Bamana people. This mud cloth is made to be a woman\u27s skirt. It shows through art of the many patterns, the Bamana culture, history, folklore, values, and everyday life of the Bamana Peopl
Investigating the Proviral and Immunogenic Effects of Sars-Cov-2 Accessory Protein 7A
Full text linkSARS-CoV-2 and related sarbecoviruses encode a set of accessory proteins (3a, 3b, 6, 7a, 7b, 8, 9b, and 10) that control host responses to infection and promote virus growth. Of these accessory proteins, 7a is set apart by its intracellular localization near coronavirus (CoV) budding sites and its incorporation into secreted virions. Initial studies utilizing a virus-like particle (VLP) system identified significant proviral effects mediated by 7a, but the system lacked the context of an actual CoV infection. To investigate 7a functions during CoV infections, we constructed recombinant Mouse Hepatitis Viruses (rMHV strain A59) that express 7a genes. Comparative infections revealed that 7a increased viral replication and viral output in immortalized murine cell cultures and in primary bone marrow-derived macrophages (BMDMs). This proviral effect was independent of a previously reported 7a-mediated interferon antagonizing activity. 7a is a type I transmembrane protein with a short cytoplasmic tail that operates in subcellular trafficking and signal transduction. To further elucidate tail functions, we generated a set of rA59 viruses expressing substitutions in the tail di-lysine motifs. Several substitutions reduced 7a proviral activities; notably the K119A change eliminated 7a support of virus yield. 7a expression was robustly proinflammatory in BMDMs, as measured cytokine arrays. Cytoplasmic tail substitutions tempered these proinflammatory responses, implying connections with proviral activities. SARS-CoV-2 infected macrophages have been implicated in inflammatory COVID-19 and these findings point to 7a cytoplasmic tails as potential contributors to cytokine-mediated disease. This study shows that SARS-CoV-2 accessory protein 7a promotes infection of a phylogenetically distinct embecovirus and in doing so elicits proinflammatory and potentially disease-relevant host responses. The findings localize and highlight a specific proviral component in a sarbecovirus accessory protein