15849 research outputs found
Sort by
The Stay SAFE Project: Implementation of an Evidence-Based Interruption Management Strategy with Novice Nurses
No full text
Tourism Effects on Reptile Biodiversity and Abundances in the Peruvian Amazon
Get PDFThe Peruvian rainforest houses many reptile species with diverse habitat preferences, complicating our understanding of their diversity and abundance. Healthy reptile populations are essential for the rainforest ecosystem\u27s health. Thus, it\u27s crucial for scientists to accurately assess reptile distribution and abundance in tropical forests and their ecological roles. This study uses visual encounter surveys to document reptile biodiversity and locations along Peru’s Madre de Dios River and Lake Sandoval. Focusing on the microhabitats during a seven-day observational period, we aim to highlight the need to preserve the natural environments where reptiles thrive and compare these areas to tourism rates
Skin microbiota differs between Black and White patients with cutaneous T-cell lymphoma
Get PDFCutaneous T-cell lymphoma (CTCL) disproportionately affects Black patients, who experience higher rates of sepsis and mortality. This study examines differences in the lesional and non-lesional skin microbiomes of Black and White CTCL patients using 16S rRNA and tuf gene sequencing. Results reveal distinct microbial compositions, with increased Staphylococcus aureus abundance in Black patients. Our team contributed by developing RStudio-based code to visualize and analyze microbiome sequencing data, facilitating clearer interpretation of microbial differences. These findings suggest microbial factors may contribute to racial disparities in CTCL outcomes, highlighting the need for targeted therapeutic interventions and further microbiome research
The Geography of Inequality: Investigating Racial Disparities in Milwaukee’s Urban Amenities
Get PDFMilwaukee is recognized as one of the most racially segregated cities in the United States, which has been reinforced by a history of systemic exclusionary policies and practices like urban renewal projects and redlining. This segregation has influenced the distribution of urban amenities which play a crucial role in shaping residents quality of life. This research investigates the distribution of urban amenities (institutional, commercial, and recreational) and their intersection with racial demographics in Milwaukee, Wisconsin by comparing maps from 1950 and 2020. The anticipated findings will inform actionable policy recommendations aimed at fostering a more equitable distribution of urban resources
Investigating The Enzymatic Redox Activity of Human Phosducin-Like Protein 2A
No full textPhosducin-like proteins (PhLPs) are a subclass of the thioredoxin (Trx) superfamily of proteins. The CryoEM structure of the chaperonin TriC/CCT complexed with PhLP2A supports the hypothesis that PhLPs are involved in the folding of cytoskeletal proteins, actin, and tubulin. However, the precise function of PhLP is not well understood. Several members of the Trx family of proteins are redox active and act as chaperones to assist protein folding. Additionally, the amino acid sequence alignment between TXNDC9 and PhLP2A reveals the redox-active cysteine to be conserved. We hypothesize that PhLP2A, like its structural homolog TXNDC9, is redox active
Building a Digital Decolonial Archive
No full textOur research was to aid in developing an archive for a Women Studies and Gender Studies and Anthropology course on decolonization.
We studied Cherrie Moraga, Gloria Anzaldua, Anibal Quijano, and Enrique Dussel to first frame our research. Then, we visited the Field Museum, the National Museum of Mexican Art, the American Indian Center, and the Newberry Library in Chicago to see if these institutions are effectively decolonizing.
With this project, we aimed to create an archive that would address how Eurocentric ideas ignore the history of the countries they exploited, recognize how colonizer nation hypocrisy is dangerous and creates the idea that the U.S. is the model for what the rest of the world should be, and to help us learn how to think through academic concepts in a non-western lens
Autism Spectrum Disorder Desirable Toy
Get PDFOur team designed a set of dinosaur-themed puzzles tailored to a child with ASD and ADHD, focusing on sensory needs, safety, and engagement. Using SolidWorks, we developed magnetic, colorful, smooth puzzle pieces that comply with Consumer Product Safety Commission standards while remaining budget friendly. Through an iterative design process, we created a portable toy that encourages independent play with simplicity. Our project highlights how thoughtful engineering can create inclusive play experiences for children with developmental differences
Telehealth in Substance use Disorder Treatment: A Pre- and Post-COVID 19 Analysis
No full textBackground: The COVID-19 pandemic necessitated a shift from in-person substance use disorder (SUD) treatment to virtual telehealth (TH) visits, creating opportunities to assess the impact of virtual visits on SUD treatment.
Methods: This study utilized retrospective, de-identified, electronic health record (EHR) data from Oracle EHR Real-World Data to examine the impact of TH on SUD treatment. Patients with a qualifying SUD diagnosis from 141 U.S. health systems were included and divided into pre-TH (January 1, 2017 through January 1, 2019) and COVID (January 1, 2020 through January 1, 2022) cohorts. This study analyzed TH utilization, medications for SUD (MSUD) prescribing, drug-related events, and mental health crises, comparing patient outcomes where the treating clinician was a high TH user versus a low TH user in both pre-COVID and COVID periods.
Results: Patients visiting high TH clinicians had lower MSUD prescribing rates, yet a higher MSUD day’s supply, and higher rates of TH outpatient visits than those visiting low TH providers, with both groups having an in crease in TH visits during the COVID period. Patients with high TH clinicians had lower rates of SUD-related hospitalizations than those with low TH providers but similar rates of drug overdoses, relapses, injection- related infections, and mental health crises.
Conclusions: TH modalities showed increased SUD-related outpatient visits without increasing adverse outcomes, indicating its potential as a sustainable alternative to in-person care. This study highlights the need for further research on TH efficacy for SUD-specific populations and supports the continued integration of telehealth in SUD treatment post-pandemic
Prenatal stress effects on sex differences in recognition memory and synaptic expression of AMPA-type glutamate receptors
No full textPrenatal stress (PRS) increases the risk of cognitive deficits in male but not female offspring. This study investigates sex-specific effects of PRS on RNA editing, AMPA receptor expression, and dendritic spine density in the dorsal CA1 hippocampus—critical for memory. Behavioral assays revealed impaired recognition memory in PRS males only. We hypothesize that reduced RNA editing and synaptic AMPA receptor localization underlie these deficits. Through immunohistochemistry, confocal imaging, and qPCR, we will assess correlations between molecular alterations and cognition. Findings may uncover mechanisms of female resilience to PRS and identify targets for treating neurodevelopmental disorders marked by cognitive impairments