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Studies Toward the Total Synthesis of Chaetoxanthone B
No full textThe goal of this project is to synthesize Chaetoxanthone B, a naturally occurring anti-malarial compound. This molecule was isolated from Chaetomium sp., a marine fungus harvested from an algae originating from Santorini, Greece. Currently, we are developing a suitable synthetic pathway to make Chaetoxanthone B starting from simple commercially available compounds because it is difficult to obtain this metabolite from the natural source. Access to larger quantities of this natural product would allow for further exploration of the anti-malarial activity and allow for the preparation of non-natural synthetic derivatives
Chronic Administration of Nicotine Does Not Improve Cognitive Flexibility in an Attentional Set-Shifting Paradigm
No full textThe attentional set-shifting task (ASST) measures cognitive flexibility in rats. Studies demonstrate that nicotine administration before testing improves performance; however, no studies have examined a chronic pre-treatment effect. To assess this, 14 daily nicotine (0.4 mg/kg) or saline injections were given, and tests were conducted drugfree. Due to reports of neuroplastic changes induced by repeated nicotine administration, this regimen was predicted to improve performance; however, this effect was not demonstrated. A locomotor activity control experiment was conducted to determine if nicotine had an effect in a separate behavioral paradigm. A subset of the pre-treated rats were given a nicotine injection and observed for locomotor activity. In agreement with previous studies, nicotine naïve rats demonstrated less activity than nicotine tolerant rats. Nicotine therefore had a behavioral effect in a paradigm separate from the ASST, suggesting nicotine must be present at test in the ASST to enhance behavior
Narratives of Mexican American Women: Emergent Identities of the Second Generation (Book Review)
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Investigating the Effects of Social Isolation on Fear and Anxiety in Male Rats: Potential Involvement of the Oxytocin Receptor
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Becoming Global Citizens: Studying Abroad
No full textLake Forest College is dedicated to preparing students to become responsible, global citizens. The experiential learning that off-campus experiences provides—through study, internship and local engagement with the culture at hand—prepares students to enter the post-graduation workforce and graduate school with a greater worldview. Expanded linguistic, social and cultural competencies gained off-campus synergistically connect a variety of majors and prepare students well for an ever-changing global workspace. Students on this panel will discuss their specific off-campus learning in the context of their academic and personal interests, and reflect on what they have gained from these cultural experiences as well as how their time studying abroad has prepared them for post-graduation achievements in an increasingly globalized world
Keeping and Killing: The Nature of Animal-Human Relationships
No full textI will focus on the complexity of animal-human relationships in the contemporary United States, drawing on literature, science, and philosophy to explore the various ways we keep and kill animals in captivity, such as in agriculture and biomedical research. By examining these interactions, we expose an inherent duality within human consciousness, which results in conflicting attitudes about our responsibilities toward animals. Often, we tell ourselves stories that make us more comfortable with these inconsistencies. By acknowledging this, we can better confront this confusion and understand how it affects animals’ lives and deaths
Defined Contribution Plans and the 2008 Financial Crisis
No full textI use the 2008 financial crisis as a natural experiment to stress test how people with defined contribution retirement plans react during recessionary periods. Using the Survey of Consumer Finances, I find that people did not significantly alter their participation rate or the percent or amount of income contributed to their DC plan. The most notable identifiable change is that DC plans were, in fact, valued more three years after the crisis than before. These findings are consistent with DC balances largely mirroring stock market activity and not being overly sensitive to behavioral responses following a financial crisis
Out of the Margins: Nature and Monsters in the Middle Ages
No full textMedieval monsters command the attention of their audiences, both past and present. It would therefore be a mistake to dismiss these creatures as mere distractions. Lurking in the liminal zones between Christian civilization and the natural world, monsters existed in medieval minds as flesh and blood beings and also acted as projections of their creator’s worries. Focusing on Beowulf’s Grendel and the “monstrous races” called blemmye and cynocephali, this presentation describes how medieval monsters and their habitats were imagined both as real creatures and places, and as actors and stages where the Middle Ages projected their cultural anxieties