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Design, synthesis and blood vessels sealing activity of 2- or 4-methyl-9h-xanthen-9-one derivatives of aminophenols or aromatic chiral or achiral aminoalkanols
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No full textObjective: To systematically review the results of maternal microbial transfer in shaping microbial diversity, improving neonatal development, and evaluating the microbial transfer procedure’s adverse events. Data Sources: A comprehensive search was conducted on April 25, 2024, using PubMed/MEDLINE, Academic Search Ultimate, and ClinicalTrials.gov for studies published in English from 2000 to 2023. The following keywords were used: "vaginal seeding," "microbiota," "maternal fecal microbiota transplantation," “maternal microbial transfer,” and “bacterial baptism.” Study Eligibility Criteria: The review included English-language, peer-reviewed randomized controlled trials and nonrandomized interventional studies investigating maternal microbial transfer in neonates born via elective cesarean delivery. Study Appraisal and Synthesis Methods: Data were extracted and analyzed for key outcomes, including severe adverse effects, alpha diversity, beta diversity, and the abundance of key taxa such as Bacteroides spp., Bifidobacterium spp., and Lactobacillus spp. Results: A total of 10 studies, including 4 randomized controlled trials and 6 nonrandomized interventional studies with 1450 participants, were included in this qualitative review. The findings regarding changes in alpha diversity (a measure of microbial richness within individual samples) were inconclusive, while several studies indicated a potential increase in beta diversity (reflecting differences in microbial composition between samples) associated with the procedure. Bacteroides spp., Bifidobacterium spp., and Lactobacillus spp. were the most frequently assessed taxa, with some studies suggesting beneficial changes in their abundance. Developmental outcomes, such as anthropometric measures and allergy risks, showed limited evidence of benefit, with one study reporting preliminary findings of improved neurodevelopmental scores. No significant increase in severe adverse effects was observed in any of the included studies. Conclusion: The efficacy of maternal microbial transfer in restoring neonatal microbiota and promoting health outcomes remains uncertain, with neonatal outcomes addressed in only 3 of the included studies - one on allergy and one on neurodevelopment. However, while no serious adverse effects have been consistently reported, data on safety remain limited
Development and characterization of metformin hydrochloride hydrogels as potential wound dressings for diabetic foot ulcers
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Cemented fixation in arthroplasty for hip fractures does not increase cardiopulmonary complications : a secondary analysis of the HIP ATTACK trial
No full textNutrition as therapy - the role of dietitian counseling : a best practice implementation project
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Attitudes towards infertility : perspectives from the African diaspora in Poland
No full textThis article examines the perspectives of Africans living in Poland on infertility and the cultural stigmatisation associated with it. By situating the discussion within the broader context of African cultural frameworks and the sociocultural dynamics of contemporary Poland, the study explores how members of this community reconcile their cultural identities with their lived experiences in a European setting. Drawing on a review of the literature on gender roles, childbearing, and reproductive health issues in Africa, the research provides insight into the small and diverse African diaspora in Poland. Through in-depth interviews with participants from various African countries, it investigates gender roles, societal pressures, and the impact of stigmatisation on perceptions of reproductive health. Additionally, it examines participants’ connections to their countries of origin and their attitudes towards adoption and the use of reproductive technologies
