137262 research outputs found
Sort by
Health-promoting and adverse pathways in the healthcare experiences of LGBTQIA+ individuals: a qualitative investigation
No full textThe current study investigated the healthcare experiences of LGBTQIA+ individuals from the perspective of the health equity promotion model, focusing on the factors that promote or hinder equitable healthcare pathways across diverse settings. A sample of 154 LGBTQIA+ individuals living in Italy responded to two open questions concerning their positive and negative experiences within healthcare settings related to their LGBTQIA+ identities. Thematic analysis identified two main themes: (1) health-promoting pathways, encompassing three subthemes (i.e. affirmation of LGBTQIA+ identities, non-judgemental attitudes and lack of prejudice, professional competence and education about LGBTQIA+ health needs); and (2) adverse pathways, encompassing four subthemes (i.e. cis-heteronormative assumptions, homo-transphobic attitudes, lack of competence and information, consequences of negative healthcare experiences). Barriers to accessing and utilising healthcare services were linked to professionals’ affirming attitudes, validation of LGBTQIA+ identities, (lack of) professionalism and prejudice, quality of information provided, and patient perceptions of competence in LGBTQIA+ health needs. The findings suggest that training on the specific health needs of LGBTQIA+ populations should be included in mental and medical healthcare curricula to enhance care quality, dismantle cis-heteronormative beliefs, and mitigate homo-transphobic attitudes that negatively impact the health trajectories of LGBTQIA+ individuals
Reappraisal of colorectal polyps in acromegaly: study on prevalence, recurrence and risk factors
No full textObjective: Investigation of colorectal polyps’ prevalence and recurrence risk factors in acromegaly. Design: Retrospective study. Methods: 171 patients referring to “Federico II” University diagnosed with acromegaly from 2000 to 2022 who underwent at least one colonoscopy. Results: Colonoscopy was performed at diagnosis in 120 (70.2%) and after a disease duration of 10.2 ± 5.7 years in 51 patients (29.8%). Polyps were found in 37.5% and 37.2%, respectively (p = 0.975). At diagnosis, polyps were found more frequently in older (p = 0.003), diabetic (p = 0.01) patients, with higher number of systemic complications (p < 0.001). Prevalence of polyps at diagnosis was significantly higher in patients with presumed disease onset greater than 6 years (median, p = 0.04). In patients who underwent colonoscopy after the diagnosis, age at diagnosis (p = 0.005), fasting glucose (p < 0.001), HbA1c (p < 0.001), HOMAIR (p = 0.009), and number of systemic complications (p = 0.004) were significantly higher in patients with than those without polyps. Forty-nine patients (34.2%) underwent multiple evaluations with 10-years median of colonoscopy follow-up. Recurrence was present in 38.2% at last evaluation, particularly in patients with uncontrolled acromegaly (p = 0.003), glucose metabolism impairment (p = 0.031), metabolic syndrome (MS, p = 0.004). New onset of polyps at last evaluation was found in 24.2% of patients with first negative colonoscopy, particularly in men (p = 0.006), with uncontrolled acromegaly (p = 0.007), and MS (p = 0.002). Patients with uncontrolled acromegaly had a risk 9.6- and 11.5- fold higher of polyps’ recurrence and new onset, respectively. Overall, six patients (3.5%) had colon cancer. Conclusions: Polyps’ recurrence and new onset are more frequent in patients with uncontrolled acromegaly, glucose metabolism impairment, and MS. Colonoscopy follow-up should be tailored, colonoscopy should be performed at diagnosis and periodically thereafter depending on acromegaly and metabolic control
Il reato di femminicidio e l’attività di contrasto alla violenza nei confronti delle donne
No full textLa legge 2 dicembre 2025 n.181, pubblicata sulla G.U. n.280 del 2 dicembre 2025 e in vigore dal 17 dicembre 2025, ha introdotto nell’ordinamento il reato di femminicidio, con altri interventi normativi per il contrasto alla violenza nei confronti delle donne e per la tutela delle vittime.
Il provvedimento consta di 14 articoli che modificano il codice penale (art.1), di procedura penale (art.3) e la legge sull’ordinamento penitenziario (art.5), oltre a specifiche previsioni di contrasto alla violenza nei confronti delle donne, che rafforzano gli obblighi formativi e informativi a tutela dalla c.d. ‘vittimizzazione secondaria’
Fondamenti matematici della teoria classica dei campi
No full textVengono studiati i fondamenti matematici e fisici della teoria classica dei campi
La “logica dell’ipermercato”. Intorno a Michel Houellebecq e la distopia del presente
No full textAbstract: The article examines Michel Houellebecq’s dystopian novels.
The French writer often uses this narrative strategy, which is very similar
to science fiction. According to Houellebecq, science fiction is one of
the most important aspects of 20th-century culture. In his dystopian
novels, the French writer shows us a world left to decay, dominated by a
culture of competition and social atomism, summarised in the expression
“hypermarket logi
Abandoned industrial heritage: From waste to resource. Which evaluation tools to evaluate this circular process?
No full textrelazione di presentazione delle tesi salienti del proprio libro Diritti in equilibrio. Stato, Regioni e cooperazione in un nuovo welfare in un confronto pubblico nel ciclo di convegni dal titolo L’autore in aula–Libri per riflettere sul presente (nella prospettiva del diritto costituzionale), coordinato dal Prof. Maurizio Malo
No full textLa relazione ha innescato un denso dibattito sulle tesi salienti del volume Diritti in equilibrio. Stato, Regioni e cooperazione in un nuovo welfare, edito da Editoriale Scientifica nel 2025
Solvent-free reactions at work towards densely functionalized targets: synthesis of 3-amino(azido)-3-deoxy-D-galactose, a key structural motif of galectin ligands
No full textA straightforward approach is reported for the synthesis of 3-deoxy-3-amino(azido)-d-galactose, a key intermediate for the synthesis of high-affinity therapeutic inhibitors of galectins. The synthetic route highlights the viable applicability of experimentally simple solvent-free reactions in nearly half of the steps in the sequence, including a procedure specifically developed for a key epoxidation step. Unlike other known synthetic approaches, the current strategy stands out for the fast and efficient SN2 steps necessary for setting the nitrogen at C-3 with the correct configuration, achieved by taking advantage of intramolecular reactions
