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Exhumed caldera structures reveal shallow syn-eruptive dyke emplacement in caldera-forming eruptions of Ischia Island
Nested structures are a common feature of large calderas, but scientists often infer their existence only through indirect observations, as later eruptive deposits cover the ring-fault zones that bound the different collapsed blocks. The inherent structural complexity of caldera systems makes them challenging to investigate directly. The Island of Ischia (southern Italy) provides a unique opportunity to examine caldera-related structures, such as ring faults and dykes, because block resurgence has uplifted the caldera floor, exhuming its deepest rocks and structures. Due to the dramatic landslide that occurred in 2022 at Casamicciola, a series of previously unobserved dykes hosted in the Mt. Epomeo Green Tuff deposits (MEGT, 62-56.5 ka) were exposed, offering an extraordinary opportunity to study their geometries, intrusion mechanisms, and petrological significance in relation to the dynamics of caldera-forming eruptions. These dykes, located along the northern slope of Mt. Epomeo, situated in the central part of the island, exhibit various shapes, including ball-chained structures, ramp-flat geometries, and orthogonal strands. They are cm-thin and meters long, intruding in the pyroclastic deposits of the intermediate part of MEGT. A notable feature is the presence of a cataclastic shell that encases the cores, composed of fragmented tuff and crystals within a glassy matrix. Petrological and geochemical analyses indicate that the dyke compositions are consistent with those of the Monte Epomeo Green Tuff (MEGT) eruption, thereby linking them to the last phase of the caldera-forming eruption. Our findings unravel the connections between these dykes and the MEGT eruption, identifying this fault zone as a ring-fault zone of the MEGT caldera and, in turn, providing new insights into the nested caldera structure of Ischia Island and the role of the ring-fault zone during subsequent block resurgence. We propose a model for the origin of the dykes, involving localized volatile-poor injections approaching the surface from a larger feeder dyke that fed the MEGT eruption. These structures, together with the deformation structures identified in the marine deposits beneath the tuff sequence, provide compelling evidence that this area represents a segment of the MEGT caldera ring-fault zone formed during the caldera-forming eruption, and that caldera block-resurgence has been accommodated by the inversion of this ring-fault zone
A unified framework for pre-screening and screening tools in oncology clinical trials
: Clinical trial enrollment in oncology remains limited by increasingly complex eligibility criteria, biomarker stratification, and fragmented clinical data, contributing to prolonged recruitment timelines and low participation rates. This review examines contemporary pre-screening and screening approaches, spanning manual workflows, health-system-embedded digital tools, and emerging artificial intelligence-enabled methods. We assess the relative strengths and limitations of large language model-based strategies, including retrieval-augmented and domain-adapted approaches, in addressing scalability, accuracy, and equity challenges. Hybrid frameworks that integrate automated screening with clinician oversight appear most effective in improving trial matching efficiency, representativeness, and timely access to investigational therapies across diverse oncology populations
Mitigation and Control of Ground Vibrations Induced in Structures Subject to Dynamic Solicitations: Implementation and Numerical Analysis
L’industria aeronautica in Campania: archeologia industriale e storia economica di un ecosistema produttivo
collana di volumi “Mores maiorum. Storie e filosofie dei diritti” (dirr. F.Casavola, F.Amarelli) edita da Editoriale Scientifica, Napoli;
Mercury contamination in Brazil related to (historical) artisanal and small-scale gold mining activity: a narrative review with quantitative synthesis
Multilayer control for group consensus of Multi-Agent Systems: A novel delay-free averaging-based stability method
Within the multilayer control framework, a role-based control architecture is introduced for the achievement of containment and group consensus control objectives in the different layers. The main novelties rely in: i) considering multiple time scales in the different interactive networks, more appropriate for real-world Multi-Agent Systems; ii) enabling a periodic rather than a continuous interaction among agents, which is beneficial in terms of communication overhead reduction. An averaging method, involving a delay-free transformation, is employed and a novel presentation of the whole networked system as rapidly time-varying system is obtained. Stability time-scale dependent LMIs conditions are derived by means of Lyapunov method. Numerical results validate the theoretical derivation
Behavioral implementation by individual-based rights structures: A full characterization
Experimental and numerical electro-thermal analysis of a pouch cell battery accounting for connection bar effects via equivalent boundary conditions on tabs
The performance of lithium-ion batteries is strongly affected by temperature. This study presents a coupled electro-thermal model of a lithium nickel manganese cobalt oxides pouch cell battery (Li-NMC), via a 2D and 3D approach for both electrical and thermal problems, respectively, validated through an experimental analysis. In particular, the model accounts for dispersive bars, which cause heat losses in both experiments and conventional use. Different fitting equations have been formulated for closure parameters, included a piecewise fitting for entropy coefficient. Convection was modelled using heat transfer correlations, providing a reproducible model with all parameters explicitly reported. Three configurations were analyzed: (i) excluding the connection bars, (ii) including them, and (iii) considering their thermal effects via a lumped capacitance method, by using an equivalent boundary condition on the battery tabs. An experimental validation was performed via thermal imaging. The model excluding bars overestimated the maximum temperature by 8.08 °C root mean square error (RMSE) for a 5C discharge, whereas the model including bars reduced this to 2.16 °C. Lumped capacitance model accurately reproduced average and maximum temperature trends, obtaining a maximum difference between the models of 0.18 °C for 5C discharge on the average temperature. The methodology was extended to a multi-cell battery module. Both maximum and average temperatures were very similar when replacing the busbar domain with equivalent boundary conditions, with deviations lower than 0.85 °C. This confirms the validity of the proposed approach in reducing computational effort while maintaining predictive accuracy at both cell and module level