Illinois State University

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    21884 research outputs found

    Inhomogeneous Branching Random Walks: Incorporating Genealogy and Density Effects

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    We introduce a novel framework using inhomogeneous branching random walks (BRWs) to model biological processes, specifically by introducing genealogy-dependence in branching rates and displacement distributions to model bacterial colony growth. Current stochastic models often either assume independent and identical behavior of individual agents or incorporate only spatiotemporal inhomogeneity, ignoring the effect of genealogy-based inhomogeneity on the long-time behavior of these processes. Such asymptotics are of independent mathematical interest and are crucial in understanding the emergence of patterns. We propose several inhomogeneous BRW models in 2D space where displacement distributions and branching rates vary with time, space, and genealogy. A combined model then uses a weighted average of positions given by these separate models to study the shape of the growth patterns. Using computer simulations, we tune parameters from these models, which are based on genealogical and spatiotemporal factors, observe the resulting structures, and compare them with images of real bacterial colonies

    #TheWriteLife #ThisLifeWeMustLive

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    This photograph is from a work-in-progress iteration of my photo exhibition titled, A Girl and Her Long Legs, A Woman Alone, Looking for A Room of Her Own . The photos are of and taken by me, and they represent my peculiar identity stories. Autobiographical and experimental, each photo features my hair, in various styles and stages of growth, and as a living metaphor and abiding witness to my identity stories. Reflecting only one-version-in-a-universe of the identities of being Woman and Writer, the exhibition title alludes to three woman writers and their work of art in word and thought: \u27A Girl and Her Long Legs\u27 references the long-and-thin-legged she-ro schoolgirl character in The Girl Who Can , the titular story in a collection by Ama Ata Aidoo; A Woman Alone... is a book of collected autobiographical writings by Bessie Head; and \u27A Room of Her Own\u27 gestures to Virginia Woolf’s extended essay, A Room of One’s Own .https://ir.library.illinoisstate.edu/ior2026/1025/thumbnail.jp

    At the Mercy of Her Pen(cil)

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    In my creative dissertation, “At the Mercy of All Things,” I seek to emphasize the ability of experimental queer writing to grow and transform expressions of mothering and care. As a queer mother-writer myself, I find experimental forms of writing to be empowering in their queerness, fluidity, ambiguity, inconclusiveness, ambivalence, and especially, their messiness. Many of my creative pieces highlight crushing cultural expectations, despair, isolation, relentlessness, and other harsh realities of caregiving that no one warns you about. Yet, the work also encompasses a spectrum of mothering and caring experience by including hope through the breaking of patterns (formally, structurally, narratively, generationally) and through co-creation. Enter Clarke: my chaotic, euphoric, glorious then-three-year-old daughter, who is seen here gleefully scribbling across printed pages of my prose poetry in middle of my attempts at outlining and organizing my work. Together, perhaps my daughter and I can create something new.https://ir.library.illinoisstate.edu/ior2026/1022/thumbnail.jp

    Procedure to Evaluate Artificial Intelligence (AI) Output for Educational and Clinical Tasks

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    As generative artificial intelligence (AI) becomes more ubiquitous and accessible, there is a call to promote awareness, implementation, and evaluation skills among AI users. Free AI platforms offer unprecedented opportunities to transform how education and healthcare tasks are approached. However, a process for evaluating AI output has yet to be standardized. The current study implemented a structured process for guiding graduate and undergraduate students through critical evaluations of various AI platforms, promoting students\u27 critical thinking and career readiness

    Collaborative Learning in Clinical Education as a Catalyst to Support Foundational Professional Competencies in Speech-Language Pathology: A Theoretical Framework

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    As a part of every speech-language pathology graduate program in the US, clinical education is an integral and required element for both academic accreditation and the eventual clinical certification for students. Clinical education is significantly important when considering overall educational models because it is an aspect of a student’s education that contributes to their ability to make connections between what is learned in the classroom and its real-world clinical application while contributing to the acquisition of competencies. The 2:1 collaborative learning model is supported by sound learning theories and evidence from the literature. A theoretical framework was created to demonstrate how a collaborative learning model can serve as a catalyst that supports the acquisition of foundational professional and knowledge and skill competencies in speech-language pathology graduate students

    Liver X Receptor α (LXRα) Regulates 5β-Reductase (AKR1D1) Expression in Avian Embryos: Implications for Yolk Steroid Metabolism

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    Steroid-mediated maternal effects are well-studied as a source of phenotypic variation. In bird eggs, the yolk contains various steroids that can influence embryonic development. However, one complicating factor in understanding how yolk steroids affect development is that the embryo metabolizes yolk steroids to regulate exposure. The 5β-reduction of steroids by the enzyme 5β-reductase (AKR1D1) has been identified as a pathway through which yolk progesterone, testosterone, and corticosterone are all metabolized early in avian development. We set out to characterize the mechanism through which AKR1D1 expression is regulated in chickens (Gallus gallus) during embryonic development. We found a synthetic and endogenous ligand (22R-hydroxycholesterol) for Liver X Receptor α (LXRα) induced AKR1D1 expression in the embryo and extraembryonic membranes on Day 2 of development. These results suggest that endogenous ligands of LXRα induce AKR1D1 expression and regulate the metabolism of yolk steroids during development

    A Brief Case Report about Mentored Self-Reflection in a Communication Disorders Survey Course

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    This report describes and analyzes a 4 ½ hour experiential learning module for entry-level undergraduates majoring in communication sciences and disorders. The module emphasizes the importance of self-reflection to future audiologists and speech-language pathologists. It illustrates the curriculum planning process (i.e., content and self-rating tools) and introduces a mentored forum grounded in personalized and constructivist learning to foster three outcomes; foundational knowledge, caring, and the human dimension (Fink, 2021; 2001). As a result, students stated they learned about why self-reflection matters and how their own dispositions could be aligned with the professions’ expectations. Students found the activities engaging, interesting, and helpful to preprofessional development and the instructor observed three key trends. Students actively discussed the intersection of acculturation experiences and self-reflection. They envisioned themselves as introspective professionals. And, they enjoyed analyzing the attributes of rating scales and interpreting the outcomes they revealed. The report concludes with implications for embedding self-reflection in undergraduate curricula

    Towards Novel Porphyrinoid Architectures: Synthesis of Porphyrin Analogues with Two Six-Membered Exocyclic Rings

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    Tripyrranes with terminal ester protective groups were prepared by reacting 7-acetoxy-4,5,6,7-tetrahydroindoles with 3,4-diethylpyrrole in refluxing acetic acid-ethanol. Dibenzyl esters were deprotected by hydrogenolysis over 10% Pd/C and the resulting dicarboxylic acids were condensed with a series of dialdehydes in the presence of trifluoroacetic acid, followed by oxidation with FeCl3 or DDQ, to give porphyrinoid products with two six-membered exocyclic rings. Reactions with a pyrrole dialdehyde gave porphyrins in 27-30% yield and good yields were also obtained using 2,5-furandicarbaldehyde and 4-hydroxy-2,6-pyridinedicarbaldehyde to prepare oxaporphyrins and oxypyriporphyrins. However, poorer results were noted for thiaporphyrins, benzocarbaporphyrins and oxybenziporphyrins due to their poor stability in solution. The UV-vis spectra for these porphyrinoids showed significant bathochromic shifts compared to structures without 6-membered carbocyclic rings and in every case the proton NMR spectra showed that the diatropic ring currents associated with the macrocycles were reduced. These data give valuable insights into the properties of modified porphyrinoid systems and provide the foundations for investigations into the preparation of new porphyrinoid architectures

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