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Numerical comparison of a combined hydrothermal carbonization and anaerobic digestion system with direct combustion of biomass for power production
No full textSynthesis, biological assessment, and structure activity relationship studies of new flavanones embodying chromene moieties
No full textLow-temperature solvent-based 3D printing of PLGA: a parametric printability study [Epub ahead of print]
No full textFrom Anne of Green Gables to Anne of the Suburbs: Lucy Maud Montgomery reimagines home in Anne of the Island
No full textL. M. Montgomery's work, including her most famous novel, Anne of Green Gables, has been tied inextricably, in both scholarship and the popular imagination, to the rural worlds of Green Gables, Avonlea and Prince Edward Island. This article positions Montgomery as a writer offering insight into early Canadian suburban life. It does so via a reading of the third “Anne” book, Anne of the Island (1915), specifically its depiction of Patty's Place, where Anne lives while a student at Redmond College (Dalhousie College) in Kingsport (Halifax, Nova Scotia). For Montgomery, the suburb is a place that combines the best of the country and the city, while moving past the limitations of both. The suburb gives Anne a home and a place of belonging in a new, urban world. Patty's Place also offers the possibility of transformation and independence, especially for women, more than any other place in the novel. This article not only provides a new perspective on one of Canada's best-loved writers, but also contributes to a slowly growing but long overdue discussion of the city and suburbs in Canadian literary criticism, which is still largely preoccupied with notions of the wilderness and of the north
The asymptotic iteration method revisited
No full textThe asymptotic iteration method is a technique for solving analytically and approximately the linear second-order differential equation, especially the eigenvalue problems that frequently appear in theoretical and mathematical physics. The analysis and mathematical justifications of the success and failure of the asymptotic iteration method are detailed in this work. A theorem explaining why the asymptotic iteration method works for the eigenvalue problem is presented. As a byproduct, a new procedure to generate unlimited classes of exactly solvable differential equations is also introduced.Natural Sciences and Engineering Research Council of Canad
Homogeneity in patterns of climate extremes between two cities: A potential for flood planning in relation to climate change
No full textInformation about potential scenarios and causes of floods is important for future planning. Historical weather data of Fredericton (New Brunswick) and Charlottetown (Prince Edward Island), the two coastal cities of Atlantic Canada, were analyzed using RClimDex, Mann–Kendall test, and Sen’s slope estimates for potential scenarios and causes of floods. Flood hazard analyses were conducted using GIS (Geographical Information System) and ArcSWAT software. The watersheds of Fredericton and Charlottetown were delineated from 25 × 25 m resolution DEMs (Digital Elevation Models) of the two cities followed by percent watershed area calculations for different elevation classes for flood generation. Over the past 100 years, there was a significant decreasing trend in the high intensity precipitation in Charlottetown supported by a significant decrease in the number of heavy precipitation days. However, maximum one-day precipitation and maximum five-day precipitation significantly increased in Charlottetown and Fredericton, respectively. Charlottetown received more annual precipitation than Fredericton. In the last 30 years, there was an event exceeding 50 mm precipitation (considered as a threshold for the return period of urban floods) in Charlottetown; Fredericton experienced such events for more than 1.5 times. For twelve times, these events occurred more than once in a year in Charlottetown as compared to fourteen times in Fredericton. Despite statistically proven similarities in the occurrence of extreme events in the two cities, the visualized flood hazards, and the mapping of watershed characteristics, no devastating floods were reported for Charlottetown. This does not necessarily mean that there had never been risks of flooding in Charlottetown. These findings may help policymakers for future developments.Natural Sciences and Engineering Research Council of Canad
The positive effect of coexisting ecosystem engineers: A unique seaweed-mussel association provides refuge for native mud crabs against a non-indigenous predator
No full textIn marine sedimentary bottoms, mussels and macroalgae have long been recognized as important autogenic engineers that create habitat and modify abiotic conditions. The structural complexity added by bivalves and macroalgae may also mediate intraguild predation amongst marine decapod crustaceans. While spatial distributions of these ecosystem engineers frequently overlap, there is limited understanding of compounded effects when more than one engineer is present. Here we demonstrate that the coexistence of two ecosystem engineers may create habitat valuable for the survival of a small native species, the Atlantic mud crab (Panopeus herbstii), in the presence of the invasive green crab (Carcinus maenas). Using laboratory and field habitat mimics, we measured mud crab survival rates as a proxy for refuge quality. We compared the refuge provided by a unique association between shells of blue mussels (Mytilus edulis) and the giant strain of Irish moss (Chondrus crispus) to that provided by bare substrate, and by each engineer alone. These experiments revealed that the association of giant Irish moss with blue mussel shells positively and non-additively increased mud crab survival compared to the other less complex habitat mimics. In contrast, parallel experiments revealed that high habitat complexity was less important for young green crabs to survive predation from large conspecifics. These results suggest that the impact of ecosystem engineers on trophic dynamics should be considered in a broader, whole-community context encompassing multiple habitat-forming species present.Natural Sciences and Engineering Research Council of Canad
Acute toxoplasmosis and pox-viral dermatitis in a juvenile bald eagle (Haliaeetus leucocephalus) in New Brunswick, Canada.
No full textAlthough birds of prey are commonly subclinically infected by Toxoplasma gondii tissue cysts, clinical disease is relatively rare in these species. The present report describes a rare case of fatal toxoplasmosis in a juvenile bald eagle in New Brunswick. Necropsy investigation revealed severe emaciation and poxviral dermatitis which partially obscured the palpebral fissures. Microscopically there was severe lymphoplasmacytic inflammation and necrosis of the lung that was associated with abundant protozoal tachyzoites. Infection with T. gondii was confirmed in the lung via immunohistochemistry and DNA sequencing.
Key clinical message:
Wildlife rehabilitation centers should be aware of the potential occurrence of acute clinical toxoplasmosis in stressed malnourished raptors.case reports2020 08importe
Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration
No full textAlzheimer’s disease (AD) is characterized by the appearance of amyloid‐β plaques, neurofibrillary tangles, and inflammation in brain regions involved in memory. Using mass spectrometry, we have quantified the phosphoproteome of the CK‐p25, 5XFAD, and Tau P301S mouse models of neurodegeneration. We identified a shared response involving Siglec‐F which was upregulated on a subset of reactive microglia. The human paralog Siglec‐8 was also upregulated on microglia in AD. Siglec‐F and Siglec‐8 were upregulated following microglial activation with interferon gamma (IFNγ) in BV‐2 cell line and human stem cell‐derived microglia models. Siglec‐F overexpression activates an endocytic and pyroptotic inflammatory response in BV‐2 cells, dependent on its sialic acid substrates and immunoreceptor tyrosine‐based inhibition motif (ITIM) phosphorylation sites. Related human Siglecs induced a similar response in BV‐2 cells. Collectively, our results point to an important role for mouse Siglec‐F and human Siglec‐8 in regulating microglial activation during neurodegeneration
ChemEscape, polymer chemistry: Solving interactive puzzles featuring scaffolded learning to promote student understanding of polymers and structure–property relationships
No full textThe introduction of polymer chemistry in undergraduate science courses is becoming more popular in recent years, introducing content into the relationships between polymer structure and physical properties in a variety of contexts. However, active learning techniques, outside of laboratory experience, for teaching polymer chemistry are extremely limited. The ChemEscape project has successfully integrated escape-room type puzzle design and course specific learning objectives into an interactive learning experience. The novel battle box design, a self-contained puzzle unit, allows for puzzles to be easily transported and applied as a teaching tool in large postsecondary classrooms as well as an outreach tool. Herein, we describe the design and application of a series of new polymer puzzles, focusing on tacticity, elasticity, and hydrophobicity, into the battle box design as well as an all-in-one backdrop design. Puzzles are scaffolded to allow for all learning to be combined in the final puzzle solution as well as a workbook provided for participants to record observations and learning during the puzzles’ solutions