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How do transgender young people experience talking about trauma with services?
No full textTransgender young people are more likely than their cisgender peers to experience trauma. Through talking about trauma, services may be able to support transgender young people to manage the impact of these events. However, research has highlighted that many trans people are concerned that disclosing trauma would be used to discredit their sense of their gender identity. To explore how transgender young people experience having conversations about trauma with services and how they understand these conversations. Six semi-structured interviews were carried out with young transgender people. Interpretative phenomenological analysis was used. The study found that all participants were aware of discourses linking experiences of trauma with transgender identities. All participants recognised these conversations as significant. Some experienced conversations to be supportive and transformative. Others found them deeply distressing, reminiscent of trauma experiences. Relationships with professionals seemed to influence these experiences, as did transphobia and relationships with other services. A trauma-informed approach should be used and professionals are encouraged to consider the potential for harm that can arise from these conversations, as well as the therapeutic element. Clinical implications and future research directions are discussed, in particular considering the recently published Cass Review (2024)
Slow philosophy in destination branding
No full textThis case study shows the application of slow philosophy in destination branding from the Destination Marketing Organisations’ (DMOs) perspective and illustrates how a national slow brand has been implemented at the local level. It is based on a qualitative study that used semi-structured in-depth interviews with DMOs’ representatives in Latvia where the slow philosophy was embedded in the national tourism brand “Latvia. Best enjoyed slowly” between 2010 and 2018. The case study demonstrates that while the slow brand has the potential to become iconic for a destination, the main challenge lies in its capability to represent a shared collective identity for larger destinations. Hence, the slow brand is more easily applied to cities, towns, or regions rather than nations. The case study provides practical recommendations for destination marketers willing to use the slow philosophy in destination marketing. The slow brand can be used in place branding if destination marketers can resolve its inclusivity and compatibility with other destination brands
Ca-, Mg-, Sc-, and Y-stabilized zirconia: High-performance support material for dry reforming of methane and solid-electrolyte material for fuel cell
No full textOur planet is currently facing dual challenges of global warming and energy crisis. The heavy reliance of the energy sector on fossil fuels significantly contributes to the accumulation of greenhouse gases, such as CH4 and CO2, in the environment atmosphere, exacerbating global warming. Stabilized zirconia-based material offer a promising solutions to address both challenges. As a catalytic support material, active sites incorporated stabilized-zirconia can facilitate the conversions of greenhouse gases like CH4 and CO2 into syngas (H2 and CO). This reaction is popularly known as dry reforming of methane (DRM). Additionally, stabilized zirconia-based materials act as solid-state electrolyte in fuel cells enabling the electrochemical conversion of H2 and O2 to generate electricity. Both processes require high-temperature stability and oxide ionic conductivity, making “Ca, Mg, Sc, Y-stabilized zirconia” an optimal choice. In DRM, the key factors influencing catalytic efficiency include metal–support interaction, reducibility, and basicity. Meanwhile, for solid oxide fuel cells, performance is governed by factors such as size-fit, charge imbalance, dopant miscibility, ion conducting phases, densification, electrolyte thickness, and grain boundary volume. This compressive review explores the dual functionality of “Ca, Mg, Sc, Y-stabilized zirconia” as a catalyst’support for DRM and as an solid electrolyte for fuel cells. The most promising research outcomes are highlighted, and future research directions are outlined. By bringing together the catalytic and fuel cell research communities, this study aims to advance sustainable energy technologies and contribute to mitigating environmental and energy crisis through the development of stabilized zirconia-based materials
Molecular biomarkers of glial activation and injury in epilepsy
Get PDFIncreasing evidence from fluid biopsies suggests activation and injury of glial cells in epilepsy. The prevalence of clinical and subclinical seizures in neurodegenerative conditions such as Alzheimer's disease, frontotemporal dementia, and others merits review and comparison of the effects of seizures on glial markers in epilepsy and neurodegenerative diseases with concomitant seizures. Herein, we revisit preclinical and clinical reports of alterations in glial proteins in cerebrospinal fluid and blood associated with various types of epilepsy. We consider shared and distinct characteristics of changes in different age groups and sexes, in humans and animal models of epilepsy, and compare them with those reported in biofluids in neurodegenerative diseases. Our analysis indicates a significant overlap of glial response in these prevalent neurological conditions. [Abstract copyright: Copyright © 2025 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Enhancing ophthalmic diagnosis and treatment with artificial intelligence
No full textThe integration of artificial intelligence (AI) in ophthalmology is transforming the field, offering new opportunities to enhance diagnostic accuracy, personalize treatment plans, and improve service delivery. This review provides a comprehensive overview of the current applications and future potential of AI in ophthalmology. AI algorithms, particularly those utilizing machine learning (ML) and deep learning (DL), have demonstrated remarkable success in diagnosing conditions such as diabetic retinopathy (DR), age-related macular degeneration, and glaucoma with precision comparable to, or exceeding, human experts. Furthermore, AI is being utilized to develop personalized treatment plans by analyzing large datasets to predict individual responses to therapies, thus optimizing patient outcomes and reducing healthcare costs. In surgical applications, AI-driven tools are enhancing the precision of procedures like cataract surgery, contributing to better recovery times and reduced complications. Additionally, AI-powered teleophthalmology services are expanding access to eye care in underserved and remote areas, addressing global disparities in healthcare availability. Despite these advancements, challenges remain, particularly concerning data privacy, security, and algorithmic bias. Ensuring robust data governance and ethical practices is crucial for the continued success of AI integration in ophthalmology. In conclusion, future research should focus on developing sophisticated AI models capable of handling multimodal data, including genetic information and patient histories, to provide deeper insights into disease mechanisms and treatment responses. Also, collaborative efforts among governments, non-governmental organizations (NGOs), and technology companies are essential to deploy AI solutions effectively, especially in low-resource settings
Working as a newly qualified Nursing Associate: Experiences and perceptions
No full textThe literature field related to the role of the Nursing Associate (NA) remains an under-researched area. This is particularly evident in the context of the newly qualified Nursing Associate. To support evidence-based care delivery and workforce development there is a need to explore and understand the role so that the curriculum and professional development once qualified can be improved and enhanced. Within the literature, Kessler et al (2020) and Coghill (2018) have examined the NA role from the employer’s perspective. This literature has demonstrated a gap in terms of the implementation of the NA role in practice and the experiences of the newly qualified NA.
In this project, data was collected through a mixed methods approach using both a quantitative online survey and data from local NHS Trusts, qualitative data via semi-structured interviews, and a creative methods approach of photo-elicitation. The purpose of using these data collection methods was to explore the lived experience of participants who have completed the NA course. When the data was analysed the following 2 Superordinate and Subordinate themes emerged: Value of the Nursing Associate: subordinate theme: self-perceptions; perceptions of others; and Scope of the Role: subordinate themes: enablers and barriers in the workplace environment; training and support. These themes highlighted that there was limited understanding of the role of the NA and that often it was viewed not as an important role but as an interim method of achieving the registered nurse qualification through further study. The data demonstrated that it was important to develop a more nuanced understanding of the role and its impact on the provision of quality care in practice
Early years physical development research paper
Get PDFThis paper presents national and international research evidence on early years physical development, motor competency, play and physical activity. It highlights the importance of early years settings as the key place to support early movement, and of early years practitioners who are critical to enabling movement opportunities as part of children’s learning. Children can spend half of their waking hours within early years settings, therefore early years education is a key place to enable habit forming behaviour and develop excitement for movement. The paper also shares a novel evidencebased approach of connecting primitive reflexes to early years physical development and demonstrates how this can help children progress in their physical development