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Sage (Salvia pilifera): determination of its polyphenol contents, anticholinergic, antidiabetic and antioxidant activities
In this work, we determined for the first time the Salvia pilifera Montbret & Aucher ex Bentham as an important source for natural products with antioxidant and antidiabetic potentials. In this context, methanol (MESP) and water (WESP) extracts were prepared from aerial parts of S. pilifera. Also, it was evaluated for antioxidant profile by eight distinguishes bioanalytical methods and inhibition effects against enzymes linked to different diseases, namely butyrylcholinesterase (BChE), acetylcholinesterase (AChE), ?-glycosidase and ?-amylase. Also, the polyphenolic compositions of MESP and WESP were evaluated by high performance liquid chromatography and tandem mass spectrometry (LC–MS/MS). Fourteen phenolics were identified in the evaporated MESP and thirteen phenolic compounds were identified in the lyophilized WESP. Also, we performed the antioxidant properties of both extracts. In order to estimate the capacity of MESP and WESP to act as antioxidants, 1,1-diphenyl-2-picryl-hydrazyl radicals (DPPH·), 2,2´-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) radicals (ABTS·+) and N,N-dimethyl-p-phenylenediamine radicals (DMPD·+), scavenging activities, ferric ions (Fe3+), Fe3+-TPTZ and cupric ions (Cu2+) reducing assays were studied. MESP and WESP were found as potent effective DPPH· (IC50: 7.05 and 8.56 µg/mL), ABTS·+ (IC50: 3.52 and 4.76 µg/mL) and DMPD·+ (IC50: 28.92 and 30.95 µg/mL) scavenging effects. On the other hand, MESP and WESP showed the potent inhibition effects against AChE (IC50: 94.93 and 138.61 µg/mL), BChE (IC50: 60.05 and 99.13 µg/mL), ?-glycosidase (IC50: 23.28 and 36.47 µg/mL) and ?-amylase (IC50: 46.21 and 97.67 µg/mL) enzymes. This study will be an innovative and guider for further studies for antioxidant properties for industrial or medicinal plants. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.King Saud University, KSUS.A. would like to extend his sincere appreciation to the Distinguished Scientist Fellowship Program at King Saud University for funding this research
Evaluation of herbage yield and nutritive value of eight forage crop species
Determining nutritional quality of indigenous forage species constitutes prerequisite to improve the productivity of ruminants. This research was carried out at the research field of the Agricultural Research and Application Center of Iğdir University, Turkey in consecutive two years (2015 & 2016) to evaluate the herbage yield and nutritive value of eight forage species having diverse genetic make-up. Eight forage species such as Kentucky bluegrass (Poa pratensis var. Geromino), Perennial rye-grass (Lolium perenne var. Ovation), Red rescue (Festuca rubra rubra var. Corail), Slender creeping red fescue (Festuca rubra tricphylla var. Pinafore), Sheep fescue (Festuca ovina var. Ridu), Tall fescue (Festuca arundinaceae var. Jaguar 4G), Chewings fescue (Festuca comutata var. Longfellow II) and Colonial bentgras (Agrostis tenuis var. Aristata) were used as plant materials and the experiment was arranged in a randomized complete design with three replications. Data on biomass yield, crude ash, crude protein, crude oil, crude cellulose, net digestible fiber (NDF), acid detergent fiber (ADF), dry matter intake (DMI), digestible dry matter (DDM) and relative feed value (RFV) were recorded during the investigation. Results of the present study indicated that species ‘Tall fescue’ (Festuca arundinaceae var. Jaguar 4G) yielded the highest herbage yield, followed by cultivar ‘Perennial rye-grass’ (Lolium perenne var. Ovation). While, ‘Kentucky bluegrass’ (Poa pratensis var. Geromino) was found to be inferior to all other forage species in the studied years. When nutritional quality was observed, the species ‘Colonial bentgrass’ (Agrostis tenuis var. Aristata) had the maximum crude protein and RFV, while cultivar ‘Perennial rye-grass’ had significantly higher RFV, DMI, DMD and the minimum fiber content, which indicated its superior quality for milch animals. © 2019, ALÖKI Kft., Budapest, Hungary
Synthesis, characterization, and applications of hemicellulose based eco-friendly polymer composites
This book presents emerging economical and environmentally friendly polymer composites that are free of the side effects observed in traditional composites. It focuses on eco-friendly composite materials using granulated cork, a by-product of the cork industry; cellulose pulp from the recycling of paper residues; hemp fibers; and a range of other environmentally friendly materials procured from various sources. The book presents the manufacturing methods, properties and characterization techniques of these eco-friendly composites. The respective chapters address classical and recent aspects of eco-friendly polymer composites and their chemistry, along with practical applications in the biomedical, pharmaceutical, automotive and other sectors. Topics addressed include the fundamentals, processing, properties, practicality, drawbacks and advantages of eco-friendly polymer composites. Featuring contributions by experts in the field with a variety of backgrounds and specialties, the book will appeal to researchers and students in the fields of materials science and environmental science. Moreover, it fills the gap between research work in the laboratory and practical applications in related industries. © Springer Nature Switzerland AG 2019
Traditional or behavioural? A combined decision making trial and evaluation laboratory and analytic network process approach for capital structure determinants of Turkish companies
The aim of this study, following a new approach under the irrationality of managers, is to investigate the most effective determinants of capital structure decisions by combining traditional capital structure determinants with managerial-behavioural biases. In line with this objective, considering the capital structure decision as one that employs multicriteria decision making, two of the multicriteria decision-making methods—namely, Decision Making Trial and Evaluation Laboratory (DEMATEL) and Analytic Network Process (ANP)—are integrated into a hybrid method to analyse the interdependent relationships among traditional capital structure determinants and managerial-behavioural biases and to prioritize them by making dual comparisons. Our findings show that managerial-behavioural biases, not traditional capital structure determinants, are more effective in the capital structure decision and that anchoring is the most influential among managerial-behavioural biases. © 2019 John Wiley & Sons, Ltd
IN THE HISTORICAL DEVELOPMENT PROCESS -mAn / mAn ATTACHMENT
Diller, sürekli gelişen canlı varlıklar olmaları yönüyle dönemin ihtiyaçlarına göre yenikelimeler türetirler. Üretken ve değişken bir yapıya sahip olan dilde, hangi ekin hangi kökegeleceği durumu, yüzlerce yıllık dil deneyiminin sonucu olarak dilin kuralları ile yapılır. İnsanlıkvar olduğu/devam ettiği sürece yeni kavramlar ve nesneler ortaya çıkacak, bunları karşılayacakyeni kelimelere ihtiyaç duyulacaktır. Bir millete ait maddi ve manevi kavramların dilde karşılığıvardır. Sosyal hayatın değişimi ile paralel olarak ihtiyaç olan bu sözcükler, çeşitli yöntemlerletüretilerek dilin söz varlığına kazandırılır. Türkçe, yapısı itibariyle kök ve ek birleşmelerinedayalı olarak kelime türetme özelliğini azami düzeyde gerçekleştirebilen bir dildir. Türkçedesözcük yapma/üretmede veya sözvarlığını zenginleştirmede en sık kullanılan yöntemlerdenbirisi eklerle yapılan türetmedir. Tek bir köke ekler koyarak, dile yeni kavramlar kolaylıklakazandırılır. Ses olaylarına bağlı olarak çeşitli değişimler gösteren ekler, dil içinde sadecefonetik unsur gibi görünmelerine rağmen işlev ve şekil yönüyle sözcüklerin ayrılmaz birparçasıdırlar.Bu çalışmada, kaynaklarda genellikle az işlek olarak gösterilen ekin kökeni konusundafarklı görüşlere yer verilmiştir. Ek, isimden isim ve fiilden isim yapma fonksiyonları üstlenmiştir.Burada, ekin kökeni ile ilgili farklı görüşlere yer verilmiş, ekin Eski Türkçeden günümüze,Türkiye Türkçesi ağızları ve çağdaş Türk lehçelerindeki durumu örneklerle desteklenmiş, ayrıcaekin üstlendiği işlevler tespit edilmiştir.Languages produce new words, according to needs of the time, in terms of beingconstantly evolving, living entities. In the language which has a productive and variablestructure, the condition which attachment will come to which root is made with the rules oflanguage as a result of hundreds of years of language experience. As long as humanity exists /continues, new concepts and objects will emerge, new words will be needed to meet them.Material and spiritual concepts belong to a nation, have counterpart in the language. Thesewords, which are needed in parallel with the change of social life, are brought in vocabulary ofthe language, derived by various methods. Turkish structurally is a language that can realize theword derivation feature at the maximum level, based on its root and attachment integrations.One of the most frequently used methods to make/produce words or enrich their vocabulary inTurkish, is the derivation with attachments. New concepts can be easily brought in, by puttingattachments to a single root. Attachments that show various changes depending on soundevents are integral parts of words with function and shape size, although they appear to be justphonetic element in the language.In this study, different views about the origin of the attachment are displayed, which aregenerally shown as a less function. Attachment has undertaken functions of making name fromname and name from verb. Here, different views about the origin of attachment are given, fromOld Turkish till today, condition of attachment in Turkey Turkish dialects and modern Turkishdialects is supported with examples, also the functions that attachment has undertaken areidentified
The Au/Cu2WSe4/p-Si photodiode: Electrical and morphological characterization
Cu2WSe4 nanosheets were synthesized by the hot-injection method and put as interfacial layers between Au metal and p-Si by spin coating technique to investigate their photoresponse and capacitor properties via I-V and C-V measurements, respectively. The XRD were operated to confirm crystalline structure of the Cu2WSe4. The TEM image revealed that the crystalline nanosheet structures of the Cu2WSe4. The I-V measurements were performed under dark and light illumination in the range 20 mW–100 mW light intensities with 20 mW interval. In addition, some diode parameters such as ideality factor, barrier height and series resistance were extracted via a various method and discussed in the details. The C-V measurements were employed for various frequency and voltages. The C-V characteristics of the device confirmed the strong dependence on the frequency and voltage. The results imparted that Au/Cu2WSe4/p-Si can be employed for photodiode, photodetector and capacitor applications. © 2018 Elsevier B.V.17401159 32-M-16 Canon Foundation for Scientific ResearchThe authors would like to thank to Selçuk University BAP office (Project Number 17401159 ) and Karamanoglu Mehmetbey University (Grand Number: 32-M-16 ) for Scientific Research Foundation
Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS
Many chronic diseases such as diabetes and Alzheimer's disease are related to the type and quality of foods, which are consumed. Particularly, various plant origin products are stated as beneficial against such kind of chronic diseases with secondary metabolites such as their phenolic structures. Satureja cuneifolia is a plant, which is consumed as an herbal tea in some regions of Turkey and that's why investigate of its biological activity is important. In our study, the anti-diabetic and anti-Alzheimer potentials of the methanol and water extracts of S. cuneifolia plant were measured via some enzymes inhibition experiments as in vitro. The antioxidant ability of the same extracts was measured via radical scavenging and reducing power methods. Also, the total phenolics and flavonoids of the plant were identified. Finally, the extracts were analyzed by the LC-MS/MS analysis and the phenolic content of S. cuneifolia was clarified. © 2019 The Author(s)King Saud University, KSUS.A. would like to extend his sincere appreciation to the Researchers Supporting Projects (RSP-2019/59) at King Saud University for funding this research
Determination of physico-mechanical properties of some domestic and foreign walnut (Juglans regia L.) varieties
In this research, we examined some of the physical (fruit dimensions, geometric mean diameter sphericity and surface area) and mechanical (puncture force, deformation, energy absorption and hardness) properties on the four different domestic (Şebin, Kaman, Bilecik and Yalova-3) and two different foreign (Chandler and Fernor) walnut (Juglans regia) varieties. For this purpose, we applied puncture force on the walnuts at the direction of width orientation (x–x), length orientation (y–y) and suture orientation (z-z). According to obtained results, there are significant differences among the walnut varieties for crustacean walnut weight and walnut weight. The maximum and minimum values of crustacean walnut weight were observed as 18.27 g and 10.98 g for Kaman and Chandler, respectively. In addition to these results, Bilecik has a maximum walnut weight – 8.71 g, while the minimum walnut weight was observed for Yalova-3 – 4.57 g. Furthermore, geometric mean diameter and sphericity values ranged to 31.93–38.57 mm and 82.78–92.54%, respectively. There are statistically significant differences on the puncture force, deformation, energy absorption and hardness according to the load axes. The maximum and minimum puncture force values were determined at the Fernor (572 N) with y–y axes and Chandler (211.9 N) with z–z axes, respectively. Also, the highest hardness and the lowest deformation values were obtained for Kaman (y–y axes) and the highest deformation and the lowest hardness were determined at Bilecik (x–x axes). The energy absorption values changed as follows: 0.455–1.086 J, 0.404–0.985 J and 0.426–1.051 J for x–x, y–y and z–z axes, respectively. © by Wydawnictwo Uniwersytetu Przyrodniczego w Lublinie
The structural and electrical characterization of Al/GO-SiO2/p-Si photodiode (vol 103, pg 452, 2018)
WOS: 000458264900036…Kahramanmaras Sutcu Imam UniversityKahramanmaras Sutcu Imam University [2017/1-82 M, 2017/5-10 YLS, 2018/2-2 YLS]We would like to thank Kahramanmaras Sutcu Imam University (Project No: 2017/1-82 M, 2017/5-10 YLS and 2018/2-2 YLS)
Glutathione S-Transferase: Purification and Characterization of from Cherry Laurel (Prunus laurocerasus L.) and the Investigation In Vitro Effects of Some Metal Ions and Organic Compounds on Enzyme Activity
In this study, the cherry laurel flesh fruit was purified to obtain glutathione S-transferase, a well-known antioxidant enzyme. Enzyme purification was performed using two separate processes: gel filtration and affinity chromatography. The sodium dodecyl sulfate electrophoresis method was used for determining enzyme purity. The optimum pH, optimum temperature, optimum ionic strength, stable pH, and KM and Vmax values for glutathione and 1-chloro-2,4-dinitrobenzene were obtained for the enzyme as follows: 7.0 in the K-phosphate buffer, 30 °C, 0.125 M, 6.5 in the K-phosphate buffer, 0.344 mM, 0.89 mM, and 0.098 EU/ml, 0.214 EU/ml. Lineweaver-Burk graphs were used to examine the in vitro enzyme activity in order to determine the inhibitory effects of some metal ions such as Cd2+, Ni2+, Cu2+, and Mg2+ and organic compounds such as sodium dodecyl sulfate (SDS), ascorbic acid (vitamin C), benzoic acid, and ethylenediaminetetraacetic acid (EDTA). The IC50 and Ki values for each of the metal ions and organic molecules were calculated. According to the results, Ca2+ metal ion and sodium dodecyl sulfate compounds were found to be the best inhibitor with a Ki value of 0.06 ± 0.04 and 0.20 ± 0.27, respectively. © 2019, Springer Science+Business Media, LLC, part of Springer Nature