Hirosaki University Repository for Academic Resources

弘前大学博士（医学）掲載誌：Journal of orthopaedic science, S0949-2658(20)30359-6, 202

山内, 翔平

 
 
 
 
 
  
  
 
Biomechanical analysis of bioabsorbable suture anchors  
for rotator cuff repair using osteoporotic and normal bone models  
 
1849  
 
 
MRI
HEALICOIL 
REGENESORB HC-RG HC-RG
2
 
 
 
(Sawbone®) 7
Sawbone® 5 pound per cubic feet (pcf) 10 pcf
TwinFix Ti 5.0 6.5mm Corkscrew FT 4.5
5.5 6.5mm polyether  ether ketone (PEEK) Healicoil PK HC-PK  4.5 5.5mm
SwiveLock PK 4.75 5.5mm Healicoil RG 4.75 5.5mm Corkscrew 
Bio 4.75 5.5 6.5mm SwiveLock BC 4.75 5.5mm
Sawbone® 12.5 mm/sec
anchor pullout AP eyelet break
EB suture break SB 3 10-pcf 5-pcf Sawbone®
N 10pcf
5pcf remaining failure load ratio RFLR
(5pcf ) / (10pcf
) 100= RFLR(%)
: Tukey  
 
anchor pullout 5pcf Sawbone® 1
EB 10pcf Sawbone® 3 EB SB
10pcf Sawbone® TwinFix Ti 6.5mm
304.0 15.2N 5pcf Sawbone® HC-PK 5.5mm
146.3 5.8N 5.5mm
10pcf Sawbone® HC-RG 266.1 7.9N 5pcf
Sawbone® HC-PK 146.3 5.8N
4.5 4.75mm HC-RG 4.75mm 10-pcf 237.9
3.5N 5-pcf 119.0 1.4N Sawbone®
RFLR HC-PK 5.5mm
62.1 HC-PK 4.5mm 51.1  
 
HC
RFLR
HC-RG
 


English

Biomechanical analysis of bioabsorbable suture anchors for rotator cuff repair using osteoporotic and normal bone models

弘前大学博士（医学）掲載誌：弘前医学, 71(1):46-54, 202

野口, 貴雄

Japanese

一般地域住民における口腔内環境と口腔細菌叢に関する研究

弘前大学博士（医学）掲載誌：JSES international, 5(2):307-313, 202

亀井, 敬太

Ulnar collateral ligament dysfunction increases stress on the humeral capitellum: a finite element analysis

弘前大学博士（医学）掲載誌：弘前医学,71(2-4):131-137, 202

飯田, 圭一郎

Prevalence and associated characteristics of aponeurotic ptosis among a general population in Japan

弘前大学博士（医学）掲載誌：弘前医学, 71(1):65-70, 202

澤田, 洋平

自家蛍光内視鏡による大腸腫瘍性病変の蛍光強度の定量分析とニューラルネットワークによる自動診断システムの試作

弘前大学博士（医学）掲載誌：PloS one, 15(8):e0236834, 202

清水, 直

Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging

岳, 喜岩

MoS2-based anode for sodium ion batteries

弘前大学博士（医学）掲載誌：Cancer medicine, 10(4):1297-1313, 202

小玉, 寛健

N-glycan signature of serum immunoglobulins as a diagnostic biomarker of urothelial carcinomas

弘前大学博士（医学）掲載誌：In vivo, 35(1):147-153, 202

中田, 真道

 
 
 
 
 
  
 
PolyIC induces retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5 
and modulates inflammation in podocytes. 
PolyIC
 
 
Toll-
like receptors (TLRs) Retinoic acid-inducible gene-I (RIG-I)-
like Receptors (RLRs) TLRs
RLRs  
RNA Polyinosinic- polycytidylic acid (polyIC)
polyIC
RLRs Retinoic acid -inducible gene-I RIG-I Melanoma differentiation-associated 
gene 5 MDA5
polyIC RIG-I MDA5
RLRs  
 
33 37 10
1% 24 polyIC (2 ng/ml-500 μg/ml) 1.5 30
RIG-I MDA5 mRNA RT-PCR Western blot
Interferon-β IFN-β Interleukin-6 (IL-6) mRNA
RT-PCR small interfering RNA (siRNA)
RIG-I MDA5
Phalloidin
Student t ANOVA P <0.05
JMP(version 14.0)  
polyIC RIG-I MDA5 mRNA
(n=3, p<0.01) IFN-β IL-6 mRNA polyIC
(n=3, p<0.01) RIG-I MDA5
polyIC IFN-β (n=3, p<0.05) IL-
6 MDA5 (n=3, p<0.01) RIG-I
polyIC
RIG-I MDA5  
 
 
Lipopolysaccharide (LPS)
TLR4 polyIC TLR3
RLRs RIG-I MDA5
polyIC RIG-I MDA5
IFN-β IL-6
siRNA RIG-I MDA5
RIG-I MDA5
RIG-I MDA5 RIG-I MDA5
IFN-β IL-6 MDA5
 
polyIC RIG-I MDA5
 
 
polyIC RLRs RIG-I
MDA5 IFN-β IL-6
RIG-I MDA5
RIG-I MDA5  
 


PolyIC Induces Retinoic Acid-inducible Gene-I and Melanoma Differentiation-associated Gene 5 and Modulates Inflammation in Podocytes

弘前大学博士（医学）掲載誌：BMJ open diabetes research & care, 8(1):e001739, 202

工藤, 和洋

 
 
 
 
 
   
Lipopolysaccharide-binding protein is a distinctive biomarker of 
abnormal pain threshold in the general Japanese population. 
Lipopolysaccharide-binding protein(LBP)
 
 
 
 (Small fiber neuropathy: SFN)
(DPN)
DPN AGE
DPN
Pain threshold from 
intraepidermal electrical stimulation: PINT DPN
 
 2017 1030
54.4 0.5 A1c HbA1c
n=894 2 T2DM-S (n=81) Impaired 
fasting glucose-subject: IFG-S n=55 3 2 HbA1c
T2DM-L(HbA1c6.5% 7.5% ) T2DM-H(HbA1c7.5% )
post-hoc test  
PINT lipopolysaccharide-binding 
protein(LBP) =0.1025, p=0.001
=0.070, p=0.034 LBP
HbA1c, FBS HOMA-IR, F-IRI
LBP >6.7mg/dL PINT 0.35mA LBP
CRP Hs-CRP p<0.01
(ATR) Hs-CRP
T2DM
T2DM-H PINT Hs-CRP, pentosidine
, 8-OHdG T2DM-H
LBP
 
 
PINT LBP
LBP LPS
LPS TLR4
2 LPS
metabolic endoxemia
DPN TLR2/4
metabolic endotoxemia SFN
DPN
 
LBP 2
LBP
LBP Hs-CRP
Hs-CRP LBP
metabolic endotoxemia 
 
PINT
8-OHdG PINT
T2DM-H DPN
DPN
DPN DPN
 
 
 


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