1697 research outputs found
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Retesting of Donor Non-ABO/D Red Cell Antigens: Is it Time to Rethink?
Full text linkIn NJ, there were no reported errors due to antigen mistyping in 2015-2017. Nationwide, there were no errors due to antigen mistyping reported to the FDA in 2017-2021.
In the US, AABB standards, in accordance with FDA/CFR, do not require secondary testing by the transfusion service of red cell antigens other than ABO and in some cases, RhD. However, some facilities choose to do secondary testing
Student and Staff Member, undated
No full textThis photo features a student and a staff member looking at a pamphlet.https://fuse.franklin.edu/ymca/1017/thumbnail.jp
Campus Commons, undated
No full textThis image features and overhead view of the commons and clocktower.https://fuse.franklin.edu/campusscences/1004/thumbnail.jp
Campus Lawn, undated
No full textThis photo features a man walking through Franklin\u27s blooming greenery next to Alumni Hall.https://fuse.franklin.edu/campusscences/1005/thumbnail.jp
Navigating Intersectionality & The Double Bind of Race & Gender: An Exploration of Black Women Higher Education Senior Leaders
No full textBlack women’s multiple minoritized identities and the double bind of sexism and racism complicate their lives and leadership. This study examined the intersectional leadership experiences of 10 Black women correlated to race, gender, racism, and sexism in the context of higher education senior leadership. It also sought to investigate the ways Black women are often regarded and treated at multiple intersections of identity as leaders. Mental health impacts and trauma at the intersection of Black women’s race, gender, and leadership were also explored. A qualitative methodology and thematic analysis were employed to yield the study’s findings. Intersectionality, Black feminist theory, critical race theory, and trauma theory, were applied to illumine Black women’s intersectional leadership experiences and challenges. The findings of this study revealed that multiple interlocking oppressions like gendered racism, bias, and microaggressions adversely impede and impact the leadership of Black women senior leaders in institutions of higher learning (Collins, 1989). In addition, the findings demonstrated that Black women are highly conscious of their intersectionality as they navigate the convolutions of systemic discrimination and ‘everyday racism’ (Bell, 1991) in higher education leadership spaces. Themes of exhaustion and burnout emphasized the extent to which racialized gendered challenges often hinder and inhibit Black women’s leadership. Additionally, these findings indicate the need for improved workplace cultures and climates as well as increased institutional responsibility for making these improvements. Implications reveal the need for better ways to make Black women leaders in higher education feel well-received and safe to lead in spaces free of oppression. Recommendations suggest the need for clearly defined institutional leadership pathways free from oppression and discrimination that recognize the value of Black women’s intersectional experiences for developing inclusive leadership spaces in higher education
Home Care Staffing Shortage: Impact on Older Adult Independence
No full textThis study was conducted to address the impact of the home care staffing shortage on older adult independence. The lack of formal caregivers has been well-documented in the literature, which, when coupled with the number of older adults who need care or will need care in the future, makes research such as this study significant. This study gathered relevant information from a sample of older adults receiving home care services that allowed for perspectives to be documented on perceptions of independence and dependence; independence enhancers; independence barriers; and knowledge, experiences, and impressions of home care services present and future. The study involved semistructured interviews with older adults receiving home care services at their residences. This method allowed for the collection of information from the study participants through a recorded interview and the environment, allowing for the documentation of any independence enhancer or barrier to be identified. Transcripts were created, allowing for coding and resulting in themes and patterns. Findings indicated older adults realized what enhanced and created barriers to independence. The home care staffing shortage impacted older adults’ independence. Still, despite the impact, older adults experienced self-actualization with episodes of states of autonomy and adaptability to circumstance
Students in Cafeteria, undated
No full textThis photo features students checking out the food options in the cafeteria at the Student Services Center.https://fuse.franklin.edu/studentservices/1004/thumbnail.jp
The Effect of Genetic Polymorphism on Tacrolimus Metabolization Rate Due to Racial Variability and Its Impact on Kidney Transplantation
No full textThis quantitative study examined tacrolimus intrapersonal variability (IPV) between racial groups and explored antibody-mediated rejection and graft loss predictors in kidney transplantation. The study included 521 adult kidney allograft recipients at Columbia University Irving Medical Center from January 1, 2015, to December 31, 2018. A one-way ANOVA revealed significant differences in IPV across racial groups (F(3, 517) = 7.745, p \u3c 0.001). Post hoc multiple comparisons using Tukey’s HSD test indicated that African Americans (AAs) exhibited significantly higher IPV (M = 39.81%, SD = 15.71%) compared to Caucasians (M = 30.32%, SD = 15.57%), Hispanics (M = 29.66%, SD = 16.79%), and Others (M = 32.06%, SD = 14.43%). Cox regression analysis revealed that IPV negatively impacted kidney allograft survival (HR = 1.029, 95% CI [1.006 - 1.052], p = 0.014). Donor-specific antibodies (DSA) increased graft failure risk by four times (HR = 4.443, 95% CI [1.728 – 11.428], p \u3c 0.002). Univariate analysis showed that high IPV (=\u3e30%) significantly reduced graft survival (¿²(1) = 4.830, p = 0.028). Additionally, regraft (HR = 3.444, 95% CI [1.631 – 7.272], p = 0.001) and DSA (HR = 8.492, 95% CI [3.978 – 18.128], p \u3c 0.001) were significant predictors of antibody-mediated rejection. In conclusion, racial variability in tacrolimus IPV significantly correlates with transplant outcomes, suggesting that genotyping-guided tacrolimus dosing may optimize drug levels and minimize rejection risk
Resilience, Self-Efficacy, and the Lived Experiences of Caregiving for Family Members with Schizophrenia
No full textCaregiving for a family member diagnosed with schizophrenia is a very deep, intimate, challenging, and demanding experience that reshapes daily routines and family dynamics. While much of the existing research and studies have greatly focused on caregiver burden, this qualitative narrative study sought to understand how caregivers define their roles, find strength, and adjust and adapt over time. Through in-depth interviews, family caregivers described detailed both emotional and physical challenges they faced, from the initial onset of symptoms to the continuing efforts of navigating unpredictable behaviors and facing complex mental health care systems.
The caregivers’ stories also revealed the support system that helped them be resilient to survive, access to necessary information, guidance and support from professionals, connection with other resources, insights they gained through lived experiences, and for them to finally seek variety of strategies and mechanisms they coped with stress, including therapeutic support and self-care approaches, as well as meaningful relationships. In their personal stories, resilience emerged as the main central vehicle, which is reflected in the caregivers’ ability to adjust, maintain hope while staying committed to their family members despite continuous ongoing uncertainty. These narratives not only portray the caregivers as individuals who face challenges, but act as a resourceful source and adaptive partners in caregiving for a family member with schizophrenia. The caregivers’ personal experiences underscore the desperate need for mental health systems that recognize and support, while collaborating with caregivers as vital contributors to the well-being of individuals living with schizophrenia
Eat, Sleep, Console Care for Infants with Neonatal Abstinence Syndrome: A Multisite Evaluation
No full textProblem: Opioid use in pregnancy continues to rise, leading to increasing cases of neonatal abstinence syndrome (NAS). Traditional management with the Finnegan Neonatal Abstinence Scoring System (FNASS) often results in pharmacologic treatment, prolonged hospitalizations, and higher costs. Inconsistent FNASS scoring at the hospital system contributed to unnecessary NICU admissions and variable outcomes. Eat, Sleep, Console (ESC) was introduced as an alternative approach, but its effectiveness had not been formally evaluated.
Aim of the Project: The aim of the quality improvement initiative was to evaluate the effectiveness of the ESC model in improving outcomes for infants with NAS across three hospitals in Central Ohio, focusing on length of stay (LOS), pharmacologic treatment rates, NICU transfers, costs, and documentation compliance.
Review of the Evidence: Evidence supports ESC as a family-centered, nonpharmacologic care model that reduces LOS, decreases medication use, and lowers costs. Meta-analyses and multicenter studies demonstrate consistent improvements in outcomes compared with FNASS-based care.
Project Design: A quality improvement program evaluation was guided by the Kirkpatrick Model at levels two through four, supported by a logic model framework. Data were collected retrospectively and prospectively over a 10-week period and analyzed outcomes, process adherence, and financial impact.
Intervention: ESC was implemented for infants ≥36 weeks’ gestation with prenatal opioid exposure. Care focused on three functional criteria: ability to eat, sleep, and be consoled. Nurses documented nonpharmacologic interventions and caregiver involvement. Huddles were initiated when infants had difficulty meeting functional goals, with escalation to NICU transfer if needed.
Significant Findings/Outcomes: Compared with FNASS care, ESC reduced LOS from 16.7 to 8.8 days, which is lower than the national average of 10 days. The pharmacological treatment rate decreased from 54.2% to 37.5%. NICU transfers dropped by 8.9%, from 55.6% to 46.7%. Average room and board costs declined from 69,396 with ESC and $17,781 for ESC-only infants. Documentation compliance reached 87.5%.
Implications for Nursing: ESC demonstrated improved infant outcomes, decreased healthcare costs, and enhanced family engagement. Nurses played a pivotal role in implementation, education, and documentation. Findings support ESC as a sustainable, evidence-based standard of care that aligns with organizational goals of quality improvement, patient-centeredness, and cost efficiency