RS Global Journals
Not a member yet
3430 research outputs found
Sort by
THE ROLE OF TELEMEDICINE AND WEARABLE DEVICES IN HEALTHCARE DELIVERY AND PHYSICAL ACTIVITY PROMOTION: A NARRATIVE REVIEW
No full textObjective: This narrative review aims to evaluate the role of telemedicine and wearable devices in healthcare delivery and physical activity promotion, highlighting applications across multiple medical specialties and their impact on patient monitoring, rehabilitation, and chronic disease management.
Methods: Relevant publications from 2018 to 2025 were retrieved from PubMed, Scopus, and Google Scholar. Included studies addressed the development, clinical utility, and behavioural impact of telemedicine platforms and wearable sensors within healthcare and exercise-related contexts.
Key findings: Telemedicine and wearable devices are increasingly incorporated across diverse medical domains. In cardiovascular and sports medicine, they support exercise monitoring, early detection of physiological changes, and post-injury rehabilitation. In oncology and chronic disease management, these technologies enable remote symptom monitoring, adherence to therapy, and personalized care plans. Wearable devices provide continuous physiological data, enhancing individualized recommendations, safety, and motivation. Telemedicine contributes to promoting physical activity through real-time feedback and remote supervision. Limitations include device accuracy, data interpretation challenges, digital literacy barriers, and regulatory and privacy concerns. Future perspectives suggest hybrid care models and artificial intelligence integration to optimize monitoring and patient outcomes.
Conclusion: Telemedicine and wearable technologies offer scalable, effective solutions for improving healthcare delivery and promoting physical activity. Their integration into clinical workflows, supported by hybrid models and equitable access strategies, has the potential to enhance monitoring, engagement, and overall health outcomes
THE ROLE OF NAPS AND DAYTIME SLEEPINESS IN STROKE RISK: A REVIEW OF THE LITERATURE FROM A PUBLIC HEALTH AND SLEEP-MONITORING TECHNOLOGY PERSPECTIVE
No full textThe aim of this review is to summarize the literature on daytime naps and their duration in relation to stroke risk, with particular emphasis on physiological mechanisms, demographic factors, and lifestyle. Analysis has shown that short naps of up to 30 minutes improve cognitive functions, blood pressure regulation, and stress hormone levels, and thus may have not only a neutral but also a beneficial effect on the human body. In contrast, long naps lasting 60–90 minutes or repeated multiple times during the day appear to significantly increase the risk of stroke, especially in older individuals with comorbidities such as diabetes, obesity, or hypertension. The mechanisms linking naps to stroke risk include changes in the autonomic nervous system, blood pressure, inflammatory status, and blood–brain barrier integrity. The authors emphasize that both nighttime sleep and daytime naps can be monitored for duration and quality using modern, widely available devices, such as wrist-worn trackers or mattress-embedded sensors, allowing objective assessment of sleep patterns and early identification of stroke risk factors. Further research is needed to develop systems for early detection of abnormal sleep and nap patterns, which could serve as a basis for implementing personalized stroke prevention strategies
EVALUATING AI FOR EPILEPSY DETECTION: AUTOMATED RECOGNITION OF CHARACTERISTIC EEG PATTERNS
No full textElectroencephalography (EEG) is a crucial diagnostic tool in epilepsy, providing high temporal resolution for detecting epileptic seizures and interictal discharges. Despite its significance, EEG analysis faces challenges such as susceptibility to artifacts, individual variability, and the need for specialized expertise.
In recent years, the rapid and intensive development of artificial intelligence (AI), in particular machine learning and deep learning methods, has shown that their application in EEG analysis can be useful in everyday clinical practice. The integration of artificial intelligence offers promising solutions to enhance EEG interpretation, automate routine analysis, and improve diagnostic accuracy. Machine learning algorithms, particularly convolutional neural networks, have demonstrated expertise-level performance in classifying EEG signals and predicting seizures, reducing clinician workload and increasing efficiency. AI applications extend to wearable devices and implantable systems for continuous seizure monitoring and personalized therapy.
However, challenges remain, including data quality, noise interference, privacy concerns, and the translation of research models into clinical practice. Future developments should focus on refining AI systems, improving dataset quality, and ensuring accessibility to enhance the diagnosis and management of epilepsy.
Methodology: For the purpose of this paper, electronic databases such as Scopus, Google Scholar, and PubMed were searched. The literature search covered publications released primarily between 2016 and 2025, with particular emphasis on studies published within the last decade, reflecting the dynamic development of artificial intelligence methods in EEG analysis. A literature review was conducted using the following keywords: electroencephalography (EEG), epilepsy diagnosis, Artificial Intelligence (AI), seizure detection, deep learning, machine learning, automated EEG analysis, neuroimaging.
Original research studies, case reports, and review articles were utilized. The search was limited to publications in Polish and English
THE NEUROENDOCRINOLOGY OF CHRONIC STRESS: EVALUATING THE CLINICAL EFFICACY OF ASHWAGANDHA (WITHANIA SOMNIFERA) ON SERUM CORTISOL AND PSYCHOSOCIAL WELL-BEING
No full textBackground: Chronic stress is a pervasive global health challenge characterized by the dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. This neuroendocrine imbalance leads to elevated serum cortisol, which subsequently triggers systemic disruptions in reproductive health, metabolic homeostasis, and psychosocial well-being. Withania somnifera (Ashwagandha), a premier adaptogen, is increasingly recognized for its ability to modulate these multifaceted stress responses.
Objective: This review evaluates the clinical efficacy of Ashwagandha in reducing serum cortisol and enhancing well-being, while synthesizing its systemic impact on the reproductive, metabolic, immune, and sleep systems.
Methods: A comprehensive synthesis of over 48 contemporary sources, including randomized controlled trials (RCTs) and meta-analyses, was conducted to assess hormonal, psychometric, and physiological outcomes.
Results: Evidence consistently demonstrates that standardized Ashwagandha extracts (240–600 mg/daily) reduce serum cortisol levels by 11% to 32%. These changes correlate with significant improvements in anxiety (PSS-10, HAM-A) and sleep parameters, specifically reduced sleep onset latency and enhanced efficiency. Beyond the HPA axis, Ashwagandha restores the hypothalamic-pituitary-gonadal (HPG) axis, significantly improving sperm concentration and testosterone levels in males. Metabolic benefits include modest weight reduction and improved insulin sensitivity, while ergogenic effects manifest as increased VO2max and accelerated muscular recovery. Furthermore, the herb exhibits immunomodulatory properties and subtle influences on thyroid indices (HPT axis), alongside emerging geroprotective potential. While generally safe, clinical monitoring for thyroid dysfunction is advised.
Conclusion: Ashwagandha functions as a robust multi-systemic regulator. Its ability to restore homeostatic balance across the HPA, HPG, and HPT axes justifies its integration into evidence-based protocols for stress management, metabolic health, and physical vitality
ESOPHAGEAL DIVERTICULUM AS A CAUSE OF ASPIRATION PNEUMONIA: A CASE REPORT
No full textAspiration pneumonia is a clinically significant condition that may result from unrecognized structural or functional abnormalities of the upper gastrointestinal tract. Esophageal diverticula, although often asymptomatic, can predispose patients to recurrent aspiration and serious pulmonary complications. This case report describes a 59-year-old female patient admitted with recurrent lower respiratory tract infections of unclear etiology. Comprehensive clinical assessment, laboratory testing, and radiological imaging revealed aspiration pneumonia secondary to a large esophageal diverticulum. Targeted antibiotic therapy was initiated, and the patient was referred for definitive surgical treatment. This case highlights the importance of considering gastrointestinal causes in patients with recurrent pneumonia and emphasizes the role of an interdisciplinary diagnostic approach
TREATMENT OF ENDOMETRIOSIS: AN UMBRELLA REVIEW OF SYSTEMATIC REVIEWS AND META-ANALYSES WITH ASSESSMENT OF EVIDENCE OVERLAP
No full textBackground: Endometriosis is a chronic inflammatory disease associated with pain, infertility, and impaired quality of life. Numerous systematic reviews and meta-analyses have evaluated available treatments but overlapping evidence and methodological heterogeneity limit interpretability.
Objective: To synthesize secondary evidence on endometriosis management using an umbrella review with explicit assessment of evidence overlap.
Methods: Systematic reviews with quantitative meta-analyses published between 2019 and 2026 were identified through PubMed. Methodological quality was assessed using AMSTAR 2. Evidence was synthesized narratively across therapeutic domains and overlap of primary studies was quantified using the Corrected Covered Area (CCA).
Results: Forty-nine systematic reviews were included. Overall, methodological quality was moderate to high. Evidence overlap was generally low but high in selected domains, particularly hormonal pretreatment before assisted reproductive technologies. Progestins and gonadotropin-releasing hormone modulators consistently reduce endometriosis-related pain. Surgical excision of ovarian endometriomas reduced recurrence but impaired ovarian reserve, while postoperative hormonal suppression reduced recurrence risk.
Conclusions: This umbrella review supports selected hormonal and surgical strategies for endometriosis management while highlighting evidence redundancy and key knowledge gaps
THE INVISIBLE INTRUDER: A REVIEW OF MICROPLASTICS ACCUMULATION IN HUMAN TISSUES AND IMPLICATIONS FOR PUBLIC HEALTH, WITH EMPHASIS ON REPRODUCTIVE HEALTH
No full textGlobal plastic production has led to widespread environmental contamination, with synthetic polymers fragmenting into microplastics (MPs) and nanoplastics (NPs). These particles have been detected in human tissues, raising questions about their health effects.
This narrative review synthesizes biomonitoring studies on MP/NP accumulation, with a focus on reproductive systems. Data from recent research show polymers in blood, lungs, placentas, breast milk, testes, and brain, linked to exposure routes such as inhalation and ingestion. The review examines potential translocation across barriers like the placenta and blood-brain barrier, as well as toxicity mechanisms, including endocrine-disrupting chemical release, oxidative stress via the Nrf2 pathway, and cellular disruption. In reproductive health, evidence indicates MP presence in ovarian follicular fluid and associations with reduced sperm quality, suggesting potential contributions to fertility trends. The review also addresses debates on neuro-accumulation and economic costs of related diseases. Findings highlight MPs as a public health concern, calling for policy measures and updated risk assessments
DIGITAL COGNITIVE-BEHAVIORAL THERAPY FOR INSOMNIA (dCBT-I) AS A METHOD OF HYPNOTIC MEDICATION REDUCTION USE
No full textIntroduction & objective: Insomnia, being an established health problem, has led to the development of various ways of treatment. While Cognitive Behavioral Therapy is a gold standard of insomnia treatment, due to cost and accessibility limitations, pharmacological methods remain widely used. The most commonly used drugs are benzodiazepines and Z-drugs, which, due to their adverse effects and high dependency risk, impose various dangers. One of the “side effects” of insomnia treatment is the development of drug dependence. Well-established methods of combating these issues concern only benzodiazepines, Z-drug medication use reduction protocols are still unavailable. However, considering both these drugs, a slow dose reduction method is believed to be the most effective and safe. The newest research examines the use of digital CBT as a tool for reducing drug dependence. The results are promising, as combining slow dose reduction with digital CBT yields better outcomes than the previous approach. However, there is still limited data on the use of digital CBT in reducing reliance on pharmacological interventions in high-risk patient groups or among patients with high levels of dependency, the development of official protocols is needed. This literature review aims to assess progress in this field of medicine.
Review methods: This review is based on a non-systematic review of PubMed articles published between 2008 and 2026.
Brief description of state knowledge: In numerous studies, the efficacy of digital CBT is a safe and effective method of insomnia treatment. Concerning previous addiction reduction methods, the only established guidelines are those concerning benzodiazepine dependency, and they involve the method of slow dose reduction. Recent clinical trials suggest that combining digital CBT with dose reduction may be an alternative, demonstrating greater efficacy in treating pharmacological dependence.
Summary: Digital CBT-I is not only an alternative to traditional face-to-face CBT for the management of insomnia but may also represent a scalable and clinically relevant strategy for reducing benzodiazepine and Z-drug dependence. Emerging evidence suggests that combining gradual dose reduction with digital CBT-I may enhance deprescribing outcomes compared with tapering alone. However, limited real‑world safety data highlight the need for further research to define better safety and protocols for dependency reduction in patients overusing benzodiazepines and Z-drugs using digital CBT
SENOLYTICS – A DISCOVERY THAT COULD TRANSFORM THE COURSE OF AGING AND CHRONIC DISEASES
No full textSenescent cells play a pivotal role in the progression of age-related diseases by promoting chronic inflammation and disrupting tissue function through the secretion of senescence-associated secretory phenotype (SASP) factors. Senolytics, a novel class of therapeutic agents, enable the selective elimination of these cells or the attenuation of their deleterious effects, offering a potential avenue to enhance healthspan. Preclinical studies and early clinical trials indicate that senolytics can improve cardiovascular function, metabolism, and physical performance, while demonstrating an acceptable safety profile. This review presents the mechanisms of action of senolytics, the current state of research, and their potential applications in metabolic, neurodegenerative, and cardiovascular diseases
ECONOMIC AND POLITICAL PROBLEMS OF THE MIDDLE EAST COUNTRIES, SECURITY POLICIES OF THE REGIONAL STATES
No full textStates have advantages and disadvantages based on their location and geographical features on the world map. Its geostrategic location necessitates the more effective and careful use of national power elements to protect states’ national interests and achieve its national goals. The aim of this study is to comprehensively examine the new threat and risk assessments made on different platforms for the Middle East; to investigate the security concerns created by the process of physically and politically changing the world map based on cultural, ethnic, religious, and sectarian grounds; and to reveal how other states, situated in the middle of a potential crisis region due to its geostrategic location, will be affected by this change. The importance of the subject stems from the belief that the survival of the states and their ability to become a regional actor depends on properly evaluating developments in the Middle East and Eastern Mediterranean. The theoretical framework of this study is formed by constructivism (social constructivism), the theory that initiated the process of changing the world map and is based on the argument that the world is socially constructed, and the "Greater Middle East and North Africa Project (GMEAP)". In light of the available resources and interpretations in the study, a descriptive/descriptive approach was followed using content and discourse analysis, a qualitative research method, in order to create a conceptual, theoretical, and historical framework. The data used, the events in the historical process, theories/theses that gained or lost importance periodically, and the impact of the interaction between practice and theory on the Middle East and Eastern Mediterranean region are presented holistically using a descriptive method