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(R1463) On the Central Limit Theorem for Conditional Density Estimator In the Single Functional Index Model
Get PDFThe main objective of this paper is to investigate the nonparametric estimation of the conditional density of a scalar response variable Y, given the explanatory variable X taking value in a Hilbert space when the sample of observations is considered as an independent random variables with identical distribution (i.i.d.) and are linked with a single functional index structure. First of all, a kernel type estimator for the conditional density function (cond-df) is introduced. Afterwards, the asymptotic properties are stated for a conditional density estimator when the observations are linked with a single-index structure from which we derive an central limit theorem (CLT) of the conditional density estimator to show the asymptotic normality of the kernel estimate of this model. As an application the conditional mode in functional single-index model is presented. As an application the conditional mode in functional single-index model is presented as well as the asymptotic ( 1 - \xi) confidence interval of the conditional mode function is given for 0 \u3c \xi \u3c 1. Simulation study is also presented to illustrate the validity and finite sample performance of the considered estimator
Right Against Self-Incrimination: Revealing the Mental Health History of Justice-Involved Youth
Get PDFIn the last two decades, the juvenile justice system has focused on the early identification of youth mental health to provide timely assessment and needed treatment. However, there are potential risks in divulging youth mental health status because the information is often made available to juvenile courts and probation departments. Many state statutes allow such information to be used in the admission of guilt, adjudication, and dispositional phases. The study reviewed state and federal statutes related to protections against self-incrimination of youth at eight different stages of the juvenile justice system. A systematic content analysis of secondary sources and legislative updates of current federal and state statutes revealed that only a handful of states provide complete protection against self-incrimination when youth disclose mental health information during mental health screening, assessments, and/or treatment. Policymakers should consider the extent to which a constitutionally protected right is circumvented in the name of mental health treatment
Ethnic Variations in Levels of Conventional Bonding among Different Black Adolescents in the United States: Implications for Behavioral Resilience
Get PDFThe quantitative study offers a description of how Caribbean-descended and African American adolescents in a national sample compare on strands of Hirschi’s conventional bond in terms of deviance and justice system involvement. Using a sample of 1,141 adolescents from the National Survey of American Life-Adolescent data, these groups were compared with tests of significance. The results indicate that belief and attachment are the most significant predictors of justice system contact. While Caribbean youth reported more deviance, this was not predictive of more justice system involvement than African Americans. Explanations for these findings and practice implications are offered
Regulatory network of miRNA, lncRNA, transcription factor and target immune response genes in bovine mastitis
No full textPre- and post-transcriptional modifications of gene expression are emerging as foci of disease studies, with some studies revealing the importance of non-coding transcripts, like long non-coding RNAs (lncRNAs) and microRNAs (miRNAs). We hypothesize that transcription factors (TFs), lncRNAs and miRNAs modulate immune response in bovine mastitis and could potentially serve as disease biomarkers and/or drug targets. With computational analyses, we identified candidate genes potentially regulated by miRNAs and lncRNAs base pair complementation and thermodynamic stability of binding regions. Remarkably, we found six miRNAs, two being bta-miR-223 and bta-miR-24-3p, to bind to several targets. LncRNAs NONBTAT027932.1 and XR_003029725.1, were identified to target several genes. Functional and pathway analyses revealed lipopolysaccharide-mediated signaling pathway, regulation of chemokine (C-X-C motif) ligand 2 production and regulation of IL-23 production among others. The overarching interactome deserves further in vitro/in vivo explication for specific molecular regulatory mechanisms during bovine mastitis immune response and could lay the foundation for development of disease markers and therapeutic intervention
Treatment considerations for foreign-born victims of human trafficking: Practical applications of an ecological framework
No full textForeign-born individuals immigrating to or residing in the United States are especially vulnerable to exploitation by traffickers. Being trafficked elevates the risk for a variety of physical and mental health problems; thus, victims will often come into contact with health professionals. Because there is a dearth of literature concerning the treatment of human trafficking victims, and especially foreign-born victims, we set out to describe the practical applications of a model that we use for the mental health treatment of victimization in this population. As has been suggested by leaders in the anti-human trafficking community, we employed a culturally sensitive version of Bronfrenbrenner’s Ecological Systems Model to provide recommendations and educational resources for treatment at the individual, interpersonal, community, and societal levels. Our recommendations should serve to inform and improve the provision of care for foreign-born victims of human trafficking
The impact of microaggressions on Black college students’ worry about their future employment: The moderating role of social support and academic achievement.
No full textObjectives: Several studies have documented the negative impact of microaggressions on anxiety among Black individuals. However, few investigations have examined the impact of microaggressions on Black college students’ worries about their future employment and potential moderating factors. We examined whether there would be an association between microaggressions and worries about future employment. Furthermore, both social support and academic achievement (measured by grade point average) were purported to moderate this association. Method: Secondary data analysis was used, with the study sample consisting of Black college students (n = 225) from a predominately White institution. Participants had a mean age of 20.43 years (SD = 1.79), with females comprising 74.80% of the sample. Results: Results revealed that social support buffered the effect of microaggressions for low-achieving students, while a buffering effect of social support was not found for high-achieving students. Conclusions: Perceived social support offers some protection against the exposure of racial microaggressions, although high-achieving Black college students (the most vulnerable to potential isolation and academic pressure) may not benefit from overall social support. (PsycInfo Database Record (c) 2021 APA, all rights reserved) Public Significance Statement—This study adds to the growing body of literature documenting the negative effects of exposure to racial microaggression on academic outcomes among Black college students. Based on our findings, exposure to racial microaggressions negatively impacted students’ worry about their future employment, with social support buffering the effect of racial microaggressions for low-achieving students but not high-achieving students. (PsycInfo Database Record (c) 2021 APA, all rights reserved
Association between trajectories of personal growth initiative and post-traumatic stress after Hurricane Harvey: A latent growth mixture modeling approach
No full textStudies examining the association between personal growth initiative (PGI) and post-traumatic stress symptoms (PTSS) have often utilized cross-sectional research designs, and as a result, the changes in the levels of PGI and its association with the trajectory of PTSS remain unclear. The current study aimed to (1) explore the different trajectories in both PGI and PTSS and (2) examine the associations of the identified trajectories between PGI and PTSS among individuals. The final sample were 419 adults who were physically residing in the area when Hurricane Harvey made landfall on 26 August 2017. The initial data collection occurred approximately 16 months after the Hurricane, and participants were asked to participate again after 1- and 3-month later. A result from the latent growth mixture modeling revealed that for PGI, the 4-class model was the best-fitting model, and for PTSS, the 3-class model was the best-fitting model. When examining the association between the trajectories of PGI and PSS, individuals classified to higher PGI subgroups were more likely to be associated with the Recovery PTSS subgroup. The current study suggests that disaster survivors with higher PGI were more likely to recover from PTSS, raising an importance of incorporating PGI to alleviate future PTSS
Stability of fucoxanthin in pasteurized skim and whole goat milk
No full textObesity has become a worldwide problem giving rise to several health issues. Fucoxanthin, a marine carotenoid with anti-obesity activity, has potential application as a biofunctional ingredient in human food. The objective of this study was to evaluate the thermal stability of fucoxanthin at pasteurization temperature and, subsequently, its storage stability in goat whole milk (WM) and skim milk (SM) at refrigeration temperature for four weeks. Additionally, the effect of supplementation of fucoxanthin on the composition of milk, pH, acidity, color, and lipid oxidation of WM and SM was evaluated during the four week storage period. Fresh goat WM and SM were supplemented with fucoxanthin at a concentration of 10.67 µg/mL (2.56 mg/240 mL of milk, one serving), pasteurized at 64◦C for 30 min and stored at 4◦C for four weeks. The quantification of fucoxanthin in WM and SM was performed every week using a HPLC method. Moreover, the effect of supplementation of fucoxanthin on the composition of WM and SM was evaluated by a LactiCheck milk analyzer, and the color was evaluated by reflectance using a HunterLab colorimeter. Lipid oxidation, as the 2-thiobarbituric acid-reactive substances (TBARS) at A532, was determined using a Spectramax Plus spectrophotometer during storage. Data were analyzed by a split-plot design using PROC MIXED of SAS. The recovery yields of fucoxanthin from the pasteurized WM and SM were 96.17 ± 1.5 % and 96.89 ± 1.5 %, respectively. Both milks exhibited high recovery yields of fucoxanthin. Fucoxanthin was stable in goat WM and SM during storage at 4◦C for four weeks. The addition of fucoxanthin, at the concentration reported to have an anti-obesity effect in humans, to pasteurized WM and SM did not affect the composition or the physicochemical properties of milks but influenced the color, especially increasing the yellowness in the samples. These results revealed that goat milk can be used as a suitable matrix for the supplementation of fucoxanthin as a biofunctional ingredient in human foods
Coverage of maternal viral load monitoring during pregnancy in South Africa: Results from the 2019 national Antenatal HIV Sentinel Survey
No full textObjectives: South Africa has made remarkable progress in increasing the coverage of antiretroviral therapy (ART) among pregnant women; however, viral suppression among pregnant women receiving ART is reported to be low. Access to routine viral load testing is crucial to identify women with unsuppressed viral load early in pregnancy and to provide timely intervention to improve viral suppression. This study aimed to determine the coverage of maternal viral load monitoring nationally, focusing on viral load testing, documentation of viral load test results, and viral suppression (viral load \u3c 50 copies/mL). At the time of this study, the first-line regimen for women initiating ART during pregnancy was non-nucleoside reverse transcriptase (NNRTI)-based regimen. Methods: Between 1 October and 15 November 2019, a cross-sectional survey was conducted among 15- to 49-year-old pregnant women attending antenatal care in 1589 nationally representative public health facilities. Data on ART status, viral load testing and viral load test results were extracted from medical records. Logistic regression was used to examine factors associated with coverage of viral load testing. Results: Of 8112 participants eligible for viral load testing, 81.7% received viral load testing, and 94.1% of the viral load test results were documented in the medical records. Of those who had viral load test results documented, 74.1% were virally suppressed. Women initiated on ART during pregnancy and who received ART for three months had lower coverage of viral load testing (73%) and viral suppression (56.8%) compared with women initiated on ART before pregnancy (82.8% and 76.1%, respectively). Initiating ART during pregnancy rather than before pregnancy was associated with a lower likelihood of receiving a viral load test during pregnancy (adjusted odds ratio = 1.6, 95% confidence interval: 1.4–1.8). Conclusions: Viral load result documentation was high; viral load testing could be improved especially among women initiating ART during pregnancy. The low viral suppression among women who initiated ART during pregnancy despite receiving ART for three months highlights the importance of enhanced adherence counselling during pregnancy. Our finding supports the WHO recommendation that a Dolutegravir-containing regimen be the preferred regimen for women who are newly initiating ART during pregnancy for more rapid viral suppression
Patterns of nutrient dynamics within and below the rootzone of collard greens grown under different organic amendment types and rates
No full textThe knowledge about nutrient dynamics in the soil is pivotal for sustainable agriculture. A comprehensive research trial can retort unanswered questions. Dynamics of nutrients sourced from organic amendment types (chicken manure, dairy manure, and Milorganite™) applied at different rates (0, 168, 336, 672 kg total N/ha) were monitored within and below the rootzone of collard greens cultivated on a sandy loam soil in Prairie View, TX, USA. Macro-and micronutrients (e.g., TN: total nitrogen, P: phosphorous, K: potassium, Na: sodium, Ca: calcium, Mg: magnesium, B: boron, Cu: copper, Fe: iron, and Zn: zinc) were analyzed from soil solution samples collected during six sampling periods from within and below the rootzone. As hypothesized, the organic amendment types and rates significantly (p \u3c 0.05 and/or 0.01) affected nutrient dynamics within and below the crop rootzone. Chicken manure released significantly more TN, P, K, Na, Ca, Mg, B, Cu, and Fe than the other two amendments. The application of chicken manure and Milorganite™ resulted in higher below-the-rootzone leachate concentration of TN, Na, Mg, and Ca than in the leachates of dairy manure. Dairy manure treatments had the lowest concentrations of TN, Ca, and Mg; whereas, Milorganite™ had the lowest concentrations of P, K, Na, B, and Cu in the collected leachates. The higher level of P (i.e., 4% in Milorganite™ as compared to 2 and 0.5% in chicken and dairy manures, respectively, might have reduced the formation of Vesicular-Arbuscular (VA) mycorrhizae—a fungus with the ability to dissolve the soil P, resulting in slow release of P from Milorganite™ treatment than from the other two treatments. Patterns of nutrient dynamics varied with rain and irrigation events under the effects of the soil water and time lapse of the amendment applications’ rates and types. All the macronutrients were present within the rootzone and leached below the rootzone, except Na. The dynamic of nutrients was element-specific and was influenced by the amendments’ type and application rate