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Acceptance Sampling Plans for Percentiles Based on the Exponentiated Half Logistic Distribution
Get PDFIn this article, acceptance sampling plans are developed for the exponentiated half logistic distribution percentiles when the life test is truncated at a pre-specified time. The minimum sample size necessary to ensure the specified life percentile is obtained under a given customer’s risk. The operating characteristic values (and curves) of the sampling plans as well as the producer’s risk are presented. Two examples with real data sets are also given as illustration
A New Adjustment of Laplace Transform for Fractional Bloch Equation in NMR Flow
Get PDFThis work purpose suggest a new analytical technique called the fractional homotopy analysis transform method (FHATM) for solving time fractional Bloch NMR (nuclear magnetic resonance) flow equations, which are a set of macroscopic equations that are used for modeling nuclear magnetization as a function of time. The true beauty of this article is the coupling of the homotopy analysis method and the Laplace transform method for systems of fractional differential equations. The solutions obtained by the proposed method indicate that the approach is easy to implement and computationally very attractive
Reichenbach Fuzzy Set of Transitivity
Get PDFFuzzy implicators are the basic ingredients of many applications. So it becomes essential to study the various features of an implicator before implementing it in any practical application. This paper discusses the properties of transitivity of a fuzzy relation on a given universe and measure of fuzzy transitivity defined in terms of the Reichenbach fuzzy implicator which is an s-implicator
Panther - March 2014 - Vol. XCIV No. 17
Get PDFhttps://digitalcommons.pvamu.edu/pv-panther-newspapers/1403/thumbnail.jp
Exploring socio-economic design implications of public housing transformation; the Nigerian experience
No full textOccupancy and funding are crucial attributes of culture in predicting public housing transformation in Nigeria. The study investigates the implication of occupancy and funding as salient socio-economic factors of housing transformation. Questionnaire survey method was used to assess users\u27 experience which was analysed using statistical analysis with structural equation model (SEM). The result indicated a good model fit of occupancy and funding as socio-economic predictors that motivates residents\u27 housing adjustment decisions. Thus, the study recommends that socio-economic indices of occupancy and ease of funding future public housing adjustments can be considered by developers at the design stage. © (2014) Trans Tech Publications, Switzerland
Evaluating common spaces in residential communities: An examination of the relationship between perceived environmental quality of place and residents\u27 satisfaction
No full textGated communities as fruits of the high-density urbanism seek for security, prestige and new lifestyle and their common space is known as a significant component that could be one of the main reasons of residential satisfaction and life quality and creating sustainable urban living space in cities. Therefore, this paper presents a way of evaluation the success of a common space with dimensions measuring the quality of the relationship that residents have with their common space. Based on these dimensions, a questionnaire was administered to residents of different residential complexes in the city of Johor in Malaysia. Data was analyzed by SPSS and descriptive analysis to show which items are most important in the context of Malaysia to estimate the level of success in a common space. In addition, the research found which environmental quality aspects have more or fewer effects on residents\u27 satisfaction
Epigenetic mechanisms in mammalian male germline
No full textEpigenetics, the alteration of gene expression without any changes in DNA sequence, has been established to be heritable. Depending upon where epigenetic marks are located, epigenetic mechanisms can influence gene expression patterns which play vital roles in development and disease. Currently, epigenetic programming in mammals includes DNA methylation and histone modifications, including their variants and RNA-associated silencing. First, DNA methylation plays an important role in genomic imprinting and X-chromosome inactivation during embryonic development and in several diseases such as cancer, ATRX syndrome, Rett syndrome, and male infertility in humans. Second, modifications of both core and variant histones have been shown to influence gene regulation through changes in nuclear chromatin structure. Lastly, non-coding RNAs knock down gene expression through diverse mechanisms including the siRNA pathway. In this review, we summarize the aforementioned epigenetic phenomena first in general and then as it relates specifically to reproduction associated with male germ cells
A review of optimal chemotherapy protocols: From MTD towards metronomic therapy
No full textWe review mathematical results about the qualitative structure of chemotherapy protocols that were obtained with the methods of optimal control. As increasingly more complex features are incorporated into the mathematical model - progressing from models for homogeneous, chemotherapeutically sensitive tumor cell populations to models for heterogeneous agglomerations of subpopulations of various sensitivities to models that include tumor immune-system interactions - the structures of optimal controls change from bang-bang solutions (which correspond to maximum dose rate chemotherapy with restperiods) to solutions that favor singular controls (representing reduced dose rates). Medically, this corresponds to a transition from standard MTD (maximum tolerated dose) type protocols to chemo-switch strategies towards metronomic dosing. © EDP Sciences, 2014
Optimal protocols for the anti-VEGF tumor treatment
No full textCancer treatment using the antiangiogenic agents targets the evolution of the tumor vasculature. The aim is to significantly reduce supplies of oxygen and nutrients, and thus starve the tumor and induce its regression. In the paper we consider well established family of tumor angiogenesis models together with their recently proposed modification, that increases accuracy in the case of treatment using VEGF antibodies. We consider the optimal control problem of minimizing the tumor volume when the maximal admissible drug dose (the total amount of used drug) and the final level of vascularization are also taken into account. We investigate the solution of that problem for a fixed therapy duration. We show that the optimal strategy consists of the drug-free, full-dose and singular (with intermediate values of the control variable) intervals. Moreover, no bang-bang switch of the control is possible, that is the change from the no-dose to full-dose protocol (or in opposite direction) occurs on the interval with the singular control. For two particular models, proposed by Hahnfeldt et al. and Ergun et al., we provide additional theorems about the optimal control structure. We investigate the optimal controls numerically using the customized software written in MATLAB®, which we make freely available for download. Utilized numerical scheme is based on the composition of the well known gradient and shooting methods. © EDP Sciences, 2014
Truncation invariant copulas for modeling directional dependence: Application to foreign currency exchange data
No full textDirectional dependence modeling has been applied to many research areas including economics, finance, biostatistics, and bioinformatics. The concept of directional dependence using copula regression functions has been introduced by Sungur [21]. So we propose a new copula family which incorporates the truncation invariant structure [20] into the generalized Farlie-Gumbel-Morgenstern (FGM) distributions. The directional dependence of the new truncated invariant FGM copulas will be also introduced in this research. We will show that there exists a directional dependence in our truncation invariant FGM copulas using Foreign Currency Exchange Data of the Canadian Dollar (CAD/USD), the Japanese Yen (JPY/USD), and the Korean Won (KRW/USD)