Sistema de Gestión del Conocimiento ANLIS MALBRÁN
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Investigadores de la UNSAM desarrollaron un suero hiperinmune contra COVID-19
No full textEl tratamiento, llevado a cabo enteramente en la Argentina y por científicos Argentinos, persigue la inmunización pasiva y consiste en administrar anticuerpos a los pacientes contra el agente infeccioso, produciendo su bloqueo y evitando que se propague
Científicos argentinos crearon un suero terapéutico anti Covid que logró neutralizar el virus
No full textEs el primer potencial medicamento innovador para el tratamiento de la infección por SARS-CoV-2 totalmente desarrollado en Argentina. Dado el resultado obtenido, se avanzará a la fase de ensayos clínicos en pacientes
Curso latinoamericano de gestión y liderazgo en enfermería : módulo 2: gestión en enfermería
No full textFil: Tapiero, Johan David. Growing Up Foundation; ColombiaFil: Rodríguez, Bibiana. Centro de Pensamiento; ColombiaFil: Edwin, Salamanca. Centro de Pensamiento; ColombiaFil: Vaccaroni, Claudia. Clínica 25 de Mayo; ArgentinaFil: Tiseira, Patricia. Instituto de Formación Docente nro.180; ArgentinaFil: Sánchez, Laura. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Epidemiología. Departamento de Vigilancia y Clínica Epidemiológica; ArgentinaFil: Rodríguez López, Javier isidro. Growing Up Foundation; ColombiaEl propósito de este módulo es introducirlos en la gestión estratégica de manera general que debe desarrollar cualquier organización en búsqueda de la planeación para la competitividad, se da de manera inicial algunas áreas de importancia en la actualidad para la generación de valor en las organizaciones y el actuar del profesional de enfermería.
Posteriormente se profundizara desde la calidad en salud teniendo una comprensión sistémica de los procesos organizacionales para traducirlo en la cultura de calidad en salud, dando como resultado una mejora continua de las acciones de enfermería para la seguridad del paciente.
Es en este contexto, enfermería fortalece su rol de gestor, coordinador, director de los procesos de atención en salud, en las organizaciones, empresas e instituciones de salud de cualquier nivel estando inmerso en un equipo interprofesional. En este rol se debe ejercer la autoevaluación e identificar en qué parte del proceso de atención su participación es primordial para la prevención, recuperación, rehabilitación y abordaje paliativo de las personas y comunidades, su atención segura desde una mejora continua.
Este módulo de capacitación está especialmente destinado a enfermeros y profesionales de salud de Latinoamérica y lo publica el Instituto Nacional de Epidemiología ANLIS (Argentina) con Growing Up Foundation (Colombia), Centro de Pensamiento de Calidad en Salud y Educación (Colombia). Colaboraron Creantum (Argentina), Universidad Nacional de Mar del Plata (Argentina), Lideres Argentinos, Clínica 25 de Mayo (Argentina) en el marco de la campaña mundial Nursing Now
Tuberculosis en Argentina
No full textDescribe los casos de tuberculosis en Argentina notificados, fallecidos, perdidos, con éxito del tratamiento y sin resultado del tratamiento
Persistent Detection of Cosavirus and Saffold Cardiovirus in Riachuelo River, Argentina
No full textFil: Riviello López, Gabriela. Prefectura Naval Argentina. Ciudad Autónoma de Buenos Aires; Argentina.Fil: Martinez, Leila Marina. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Virología; Argentina.Fil: Freyre, Laura. Prefectura Naval Argentina; Argentina.Fil: Freire, María Cecilia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Virología; Argentina.Fil: Vladimirsky, Sara. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Virología; Argentina.Fil: Rabossi, Alejandro. IIBBA-CONICET and FIL; Argentina.Fil: Cisterna, Daniel Marcelo. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas. Departamento de Virología; Argentina.Cosaviruses (CoSV) and Saffold cardiovirus (SAFV) are novel members of the Picornaviridae family. The Matanza-Riachuelo river basin covers a total area of 2200 km2 with approximately 60 km long. Its last section is called Riachuelo River. The aim of this study was to describe the circulation of both picornaviruses and their relationship with the environmental situation of the Riachuelo River using 274 samples collected from 2005 to 2015. CoSV and SAFV were investigated in samples available by two periods: 2005-2006 and 2014-2015 (103 and 101, respectively). Physicochemical and bacteriological parameters confirmed very high levels of human fecal contamination during the 11 years evaluated. CoSV was detected in 85.7% (66/77) and 65.4% (17/26) of the samples collected in 2005-2006 and 2014-2015 periods, respectively. Species A and D were identified, the first one being widely predominant: 74.1% (20/27) and 75.0% (3/4) in both periods. SAFV virus was detected in 47.1% (32/68) and 52.6% (10/19) in periods 2005-2006 and 2014-2015, respectively. SAFV-6 was the most identified genotype in the entire study, while SAFV-3 was predominant in 2005-2006. The contribution of genotypes 1, 2, 4 and 8 was minor. The high prevalence of CoSV and SAFV suggests that both viruses have been circulating in Argentina at least since 2005. Our results show that a watercourse with high rates of human fecal contamination can become a persistent source of new viruses which capacity to produce human diseases is unknown
TRIO-related intellectual disability with microcephaly: a case report of a patient with novel clinical findings
No full textFil: Bevilacqua, Florencia. ANLIS Dr.C.G.Malbrán. Centro Nacional de Genética Médica. Departamento de Diagnóstico Médico; Argentina.Fil: Alberto, Guillermo. ANLIS Dr.C.G.Malbrán. Centro Nacional de Genética Médica. Departamento de Diagnóstico Médico; Argentina.Fil: Duarte, Santiago Pablo. ANLIS Dr.C.G.Malbrán. Centro Nacional de Genética Médica. Departamento de Diagnóstico Médico; Argentina.Fil: Serra, Marina. ANLIS Dr.C.G.Malbrán. Centro Nacional de Genética Médica. Departamento de Diagnóstico Médico; Argentina.Fil: Basterra, Julieta. ANLIS Dr.C.G.Malbrán. Centro Nacional de Genética Médica. Departamento de Diagnóstico Médico; Argentina.Fil: Espeche, Lucía. Department of Clinical GeneticsFil: Cerretini, Roxana Inés. Department of Clinical GeneticsFil: Solari, Andrea Paula. ANLIS Dr.C.G.Malbrán. Centro Nacional de Genética Médica. Departamento de Diagnóstico Médico; Argentina
Serosurvey of West Nile virus (WNV) in free-ranging raptors from Brazil
Full text linkFil: Morel, Ana Paula. Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF). Centro de Pesquisa em Saúde Animal, Eldorado do Sul, Río Grande del Sur; Brasil.Fil: Webster, Anelise. Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF). Centro de Pesquisa em Saúde Animal, Eldorado do Sul, Río Grande del Sur; Brasil.Fil: Zitelli, Larissa Calo. Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF). Centro de Pesquisa em Saúde Animal, Eldorado do Sul, Río Grande del Sur; Brasil.Fil: Umeno, Karen. Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF). Centro de Pesquisa em Saúde Animal, Eldorado do Sul, Río Grande del Sur; Brasil.Fil: Souza, Ugo Araújo. Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF). Centro de Pesquisa em Saúde Animal, Eldorado do Sul, Río Grande del Sur; Brasil.Fil: Prusch, Fabiane. Clinica Veterinária Toca dos Bichos, Porto Alegre, Río Grande del Sur; Brasil.Fil: Anicet, Marina. Clinica Veterinária Toca dos Bichos, Porto Alegre, Río Grande del Sur; Brasil.Fil: Marsicano, Gleide. Clinica Veterinária Toca dos Bichos, Porto Alegre, Río Grande del Sur; Brasil.Fil: Bandarra, Paulo. Nucleo de Reabilitação da Fauna Silvestre-UFPel, Pelotas, Río Grande del Sur; Brasil.Fil: Trainini, Gustavo. Hayabusa Consultoria Ambiental, São Francisco de Paula, Río Grande del Sur; Brasil.Fil: Stocker, Julian. Hayabusa Consultoria Ambiental, São Francisco de Paula, Río Grande del Sur; Brasil.Fil: Giani, Denise. Hayabusa Consultoria Ambiental, São Francisco de Paula, Río Grande del Sur; Brasil.Fil: Fortes, Flávia Borges. Secretaria da Agricultura Pecuária e Desenvolvimento Rural (SEAPDR). Programa Estadual de Sanidade Avícola (PESA), Porto Alegre, Río Grande del Sur; Brasil.Fil: Goenaga, Silvina. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.Fil: Reck, José. Instituto de Pesquisas Veterinárias Desidério Finamor (IPVDF). Centro de Pesquisa em Saúde Animal, Eldorado do Sul, Río Grande del Sur; Brasil.West Nile virus (WNV) is a mosquito-borne Flavivirus that can affect birds, horses, and humans, and is the only zoonotic Flavivirus that has been identified in six continents. In Brazil, until 2010, there was no evidence of WNV circulation. Recently, the virus was isolated from a horse with encephalitis, and the first human cases were registered in Brazil. Despite that, there is still no information on the enzootic cycle of this virus in birds or wildlife. This study aimed to investigate whether there is evidence of WNV circulation among wild birds from Southern Brazil. For this, we used free-living wild raptors (live-trapped or rescued) as potential sentinels to investigate the presence of WNV antibodies using ELISA and plaque reduction neutralization test (PRNT) assay. In addition, the presence of nucleic acids from Flavivirus family members was investigated. None of the birds sampled presented clinical findings compatible with WNV. Of the 200 serum samples from birds of prey belonging to 21 species, ten (5%) were positive for the presence of WNV antibodies on ELISA testing. The PRNT test did not confirm the ELISA results, but indicated that three birds had possibly been exposed to Saint Louis encephalitis virus (SLEV). All samples were negative for Flavivirus RNA. The results presented here evince the need for permanent surveillance for emerging flaviviruses in Brazil, as well as for a contingency policy in the case of human/animal outbreaks, particularly in high-risk areas
Multidrug-Resistant CTX-M and CMY-2 Producing Escherichia coli Isolated from Healthy Household Dogs from the Great Metropolitan Area, Costa Rica
No full textRodríguez-González, María José. Universidad Nacional de Costa Rica. Escuela de Medicina Veterinaria. Programa de Investigación en Enfermedades Tropicales, Heredia; Costa Rica.Jiménez-Pearson, María Antonieta. Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud, San José; Costa Rica.Duarte, Francisco. Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud, San José; Costa Rica.Poklepovich, Tomás. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Campos, Josefina. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Araya-Sánchez, Luis Nazario. Universidad Nacional de Costa Rica. Escuela de Medicina Veterinaria, Heredia; Costa Rica.Chirino-Trejo, Manuel. University of Saskatchewan. Western College of Veterinary Medicine, Saskatoon, Canadá.Barquero-Calvo, Elías. Universidad Nacional de Costa Rica. Escuela de Medicina Veterinaria. Programa de Investigación en Enfermedades Tropicales, Heredia; Costa Rica.Objective: This study aimed to determine the prevalence of fecal carriage of antibiotic-resistant Escherichia coli of healthy household dogs with an emphasis on extended-spectrum β-lactamases (ESBL), AmpC-type β-lactamases and resistance to quinolones. Materials and Methods: Rectal swabs were collected from 74 dogs without any clinical evidence of gastrointestinal disease. Samples were cultured on MacConkey agar plates and MacConkey supplemented with 2 μg/mL cefotaxime or 5 μg/mL ciprofloxacin. Isolates were identified with Vitek 2 Compact and susceptibility testing performed by Kirby Bauer disk diffusion method. Minimal inhibitory concentration (MIC) was done on isolates resistant to cefotaxime, ciprofloxacin, and nalidixic acid. PCR amplification was performed to detect CTX-M and CMY-2. Isolates positive for CTX-M and/or CMY-2 were selected for whole-genome sequencing. Results: Multiresistance was detected in 56% of the isolates. A high percentage of resistance was detected for cefazolin (63%), ampicillin (54%), streptomycin (49%), nalidixic acid (42%) and tetracycline (38%). The MIC50 and MIC90 for isolates resistant to cefotaxime (24%) was determined as 16 and >250 μg/mL, respectively; for ciprofloxacin (18%), 125 and 250 μg/mL, respectively. ESBL (CTX-M type) and AmpC (CMY-2 type) were detected in 6 (7.1%) and 14 (19%) of the isolates, respectively. Whole-genome sequence analysis showed high genetic diversity in most of the isolates and a large variety of resistance mechanisms, including mobile genetic elements. Conclusion: The frequency of multidrug-resistant E. coli is worrying, mainly because of the presence of many isolates producing ESBL and AmpC β-lactamases. Based on the "One Health" concept, considering the relationships between animals, humans, and the environment, these data support the notion that companion animals are important reservoirs of multidrug-resistant bacteria