RUNA - Repositorio de Saúde
Not a member yet
11570 research outputs found
Sort by
Uptodate. Cómo se utiliza Menú horizontal
No full textUptodate8El vídeo explica como utilizar la navegación desde el menú horizontal y sus herramientas: pathways, búsquedas de fármacos, novedades, navegar por especialidades, información para pacientes, etc
Estratexia galega en enfermidades raras 2021-2024
Get PDFO obxectivo central da estratexia é establecer un novo modelo asistencial para as enfermidades raras, optimizado e baseado en criterios homoxéneos para garantir un prazo de diagnóstico máis reducido, menor variabilidade no manexo do/a paciente e outra xestión máis áxil, coordinada e eficiente.El objetivo central de la estrategia es establecer un nuevo modelo asistencial para las enfermedades raras, optimizado y basado en criterios homogéneos para garantizar un plazo de diagnóstico más reducido, menos variabilidad en el manejo del/a paciente y otra gestión más ágil, coordinada y eficiente
Identification of e-young chronics through questionnaire
Get PDFBackground and Aims: Transforming the doctor-patient re lationship from analog to digital is no simple task and requires a great deal of courage and visionary leadership. The first step to do so is to identify the digital capabilities that the ultimate re cipient of every health system possesses: the patient. Methods: A scale questionnaire of 5 questions related to digital applications is carried out to patients under follow-up for type 1 diabetes mellitus, between 18–65 years old, who are prescribed the Abbott Freestyle Libre flash glucose monitoring device, which requires their connection to a mobile application (Libreview) by the user, for optimal use and communication of data with the healthcare professional electronically. Results: 62 patients were included.In the classification by predefined subgroups according to the questionnaire score, 35 patients (56.45%) were identified as having advanced training; 16 (25.81%) of basic training and 11 (17.74%) without digital training. 82.86% (29/35) of the patients predefined as highly qualified used the system adequately, compared to 43.75% (7/16) of those with low training and 0% (0/11) of patients without technological capabilities; p < 0.001. Conclusions: The coronavirus-19 pandemic has subjected our health services to a stress test like never before. In the current remote care scenario, we are presented with an opportunity (the great opportunity) to serve people immersed in the digital age. It would be bad news if after this pandemic, we returned to the starting box, the identification of those e-young and e-senior chronics patients is the first essential step to avoid it. Comunicación-póster presentada en: ATTD Advanced Technologies & Treatments for Diabetes Conference Online del 2 al 5 june 2021
Decline of tuberculosis rates and Covid-19 pandemic. Fact or fiction?
No full textLas medidas de distanciamiento social y aislamiento respiratorio, incluyendo el uso generalizado de mascarillas, contribuyen de manera positiva al descenso de la incidiencia de TB en nuestro medio
IV Concurso carteis para escolares relacionado coa doazón e os transplantes: a vida, o mellor agasallo
No full textCartel polo que se convoca o IV Concurso de carteis dirixido a rapaces e rapazas do curso escolar 2021/22, que ten como tema a doazón e os transplantes. A finalidade é achegar esta realidade á poboación escolar da nosa comunidade autónoma, de modo que a mocidade sexa capaz de valorar os beneficios que o fomento da doazón ten para a cidadanía.Cartel por el que se convoca el IV Concurso de carteles dirigido a jóvenes del curso escolar 2021/22, que tiene como tema la donación y los trasplantes. La finalidad es acercar esta realidad a la población escolar de nuestra comunidad autónoma, de modo que la juventud sea capaz de valorar los beneficios que el fomento de la donación tiene para la ciudadanía
The Asian wasp Vespa velutina nigrithorax: Entomological and allergological characteristics
Get PDFThe yellow-legged or Asian wasp (Vespa velutina nigrithorax) has spread rapidly across Europe since its first introduction in France, in 2004. Originally from South-East Asia, it is considered an invasive species outside its native region. Apart from the ecological and economic implications of its presence, it may cause health problems to humans due to the toxic and allergenic components of its venom. Vespa velutina nigrithorax has become the most prevalent cause of anaphylaxis due to Hymenoptera venom in some regions of Spain. Although sIgE against both antigen 5 (Vesp v 5) and A1-phospholipase (Vesp v 1) has been detected in these patients, only Vesp v 5 may be considered a dominant allergen. Interestingly, Vesp v 1 appears to be a glycosylated allergen different from A1-phospholipases from other species. Inhibition studies suggest that Vespula spp venom could behave as primary sensitizer. Besides, changes in sIgE and sIgG4 during Vespula venom immunotherapy in patients with anaphylaxis due to V. velutina support the use of Vespula venom extracts to treat these patients. The purpose of this review is to explore the biological behaviour of V. velutina and to summarize the current knowledge of the allergic reactions provoked by this wasp
Bone Mineralization and Calcium Phosphorus Metabolism
No full textThe accretion of adequate mineral content is essential for normal bone mineralization [...]
Mediastinal staging for non-small cell lung cancer
No full textThe staging of mediastinal lymph nodes for lung cancer is crucial for planning treatments or reinterventions. In potentially curable patients the aim of mediastinal staging is to exclude the presence of malignancy in mediastinal lymph nodes with a high level of accuracy while also considering clinical factors and the balance of the benefits and risks of tissue sampling techniques. Mediastinal staging is based on computed tomography (CT) and positron emission tomography (PET) and can be sufficient when no mediastinal abnormalities are present and the probability of unforeseen N2 disease is low. In the case of bulky lymph nodes with a high probability of malignancy in PET-CT, tissue confirmation is not normally required. If mediastinal sampling is needed it can be achieved by endosonographic techniques, including endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) or a combination of the two. Positive results do not need further confirmation. In the case of negative results, surgical techniques still play a role in the selected cases discussed by multidisciplinary lung cancer committees. New mediastinal surgical techniques including video-assisted cervical mediastinoscopy (VACM), video-assisted mediastinoscopic lymphadenectomy (VAMLA), and transcervical extended mediastinal lymphadenectomy (TEMLA) have been shown to be useful in selected patients. Final pathological staging is based on lymph node removal during surgery and can be achieved by taking one of two approaches: lymph node sampling or systematic lymph node sampling. The accuracy of PET-CT and mediastinal endosonography is lower for mediastinal restaging than it is for surgical techniques; their false positive and false negative (FN) rate is high and so, they require histological confirmation. Here we explain and revise the results from the most recent studies and current international guidelines
Application and Perspectives of MALDI-TOF Mass Spectrometry in Clinical Microbiology Laboratories
Get PDFEarly diagnosis of severe infections requires of a rapid and reliable diagnosis to initiate appropriate treatment, while avoiding unnecessary antimicrobial use and reducing associated morbidities and healthcare costs. It is a fact that conventional methods usually require more than 24-48 h to culture and profile bacterial species. Mass spectrometry (MS) is an analytical technique that has emerged as a powerful tool in clinical microbiology for identifying peptides and proteins, which makes it a promising tool for microbial identification. Matrix assisted laser desorption ionization-time of flight MS (MALDI-TOF MS) offers a cost- and time-effective alternative to conventional methods, such as bacterial culture and even 16S rRNA gene sequencing, for identifying viruses, bacteria and fungi and detecting virulence factors and mechanisms of resistance. This review provides an overview of the potential applications and perspectives of MS in clinical microbiology laboratories and proposes its use as a first-line method for microbial identification and diagnosis
Molecular Pathophysiology of Autosomal Recessive Polycystic Kidney Disease
Get PDFAutosomal recessive polycystic kidney disease (ARPKD) is a rare disorder and one of the most severe forms of polycystic kidney disease, leading to end-stage renal disease (ESRD) in childhood. PKHD1 is the gene that is responsible for the vast majority of ARPKD. However, some cases have been related to a new gene that was recently identified (DZIP1L gene), as well as several ciliary genes that can mimic a ARPKD-like phenotypic spectrum. In addition, a number of molecular pathways involved in the ARPKD pathogenesis and progression were elucidated using cellular and animal models. However, the function of the ARPKD proteins and the molecular mechanism of the disease currently remain incompletely understood. Here, we review the clinics, treatment, genetics, and molecular basis of ARPKD, highlighting the most recent findings in the field