HAL - Lille 3
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Non-parametric statistical analysis of spatially distributed functional data
No full textInternational audienceA nonparametric estimator of the regression function of a scalar spatial variable, given a functional spatial variable is proposed. Mean square and almost complete consistencies of the estimator are obtained when the sample considered is an a-mixing sequence and composed of non-i.i.d observations. Lastly, an application to spatial prediction and numerical results is provided to illustrate the behavior of our estimator
Peut-on avoir la ‘mouche’ à l’oreille ? ~ ¿Puede uno andar con la ‘pulga’ detrás de la oreja? Essai d’approche comparée et non-représentationnaliste de quelques unités phraséologiques du français et de l’espagnol
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Mécanismes de réécriture dans la Estoria de Espanna. Analyse comparative de quelques chapitres de la version primitive (ms. E1 & T, v. 1270) et de la version critique (ms. SS, v. 1282-1284)
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La coalescence en espagnol. Vers une linguistique du signifiant énactivisante
No full textInternational audienceLorsque deux éléments qui interagissent dans la construction de la phrase finissent par ne faire qu’un seul mot se produit ce que cet ouvrage appelle une coalescence : tan bien > también, cual quier > cualquier en espagnol ; dès jà > déjà, pour tant > pourtant en français. Cherchant à comprendre les mécanismes qui président à cette création de signifiants qui ne sont pas que la somme de leurs parties, ce livre se fixe trois objectifs :1. Cerner le phénomène et en tracer les enjeux en le distinguant d’autres modes de construction de mots (composition, agglutination, conglomération, amalgame) ;2. Proposer de la coalescence une analyse par le signifiant, c’est-à-dire par la relecture d’un fragment phrastique selon l’expérience que s’en donnent les sujets – à la fois analogique et submorphémique ;3. Contribuer à la construction d’une « linguistique du signifiant énactivisante », centrée sur l’expérience du signifiant en tant que matérialité processuelle, où les unités de langue sont moins pensées comme des donnés que comme des émergences.L’ouvrage fait une large place à l’épistémologie de cette proposition théorique
Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging
No full textInternational audienceCellular senescence is induced by stresses and results in a stable proliferation arrest accompanied by a pro-inflammatory secretome. Senescent cells accumulate during aging, promoting various age-related pathologies and limiting lifespan. The endoplasmic reticulum (ER) inositol 1,4,5-trisphosphate receptor, type 2 (ITPR2) calcium-release channel and calcium fluxes from the ER to the mitochondria are drivers of senescence in human cells. Here we show that Itpr2 knockout (KO) mice display improved aging such as increased lifespan, a better response to metabolic stress, less immunosenescence, as well as less liver steatosis and fibrosis. Cellular senescence, which is known to promote these alterations, is decreased in Itpr2 KO mice and Itpr2 KO embryo-derived cells. Interestingly, ablation of ITPR2 in vivo and in vitro decreases the number of contacts between the mitochondria and the ER and their forced contacts induce premature senescence. These findings shed light on the role of contacts and facilitated exchanges between the ER and the mitochondria through ITPR2 in regulating senescence and aging
Machine learning modelling of neuropsychological performance could determine vocational training outcome after a brain injury: Case report
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Impact of Facial Landmark Localization on Facial Expression Recognition
No full textInternational audienceAlthough facial landmark localization (FLL) approaches are becoming increasingly accurate in identifying facial components, one question remains unanswered: what is the impact of these approaches on subsequent, related tasks? In this paper, we focus on facial expression recognition (FER), where facial landmarks are used for face registration, which is a common usage. Since the common datasets for facial landmark localization do not allow for a proper measurement of performance according to the different difficulties (e.g., pose, expression, illumination, occlusion, motion blur), we also quantify the performance of recent approaches in the presence of head pose variations and facial expressions. Finally, we conduct a study of the impact of these approaches on FER. We show that the landmark accuracy achieved so far by optimizing the euclidean distance does not necessarily guarantee a gain in performance for FER. To deal with this issue, we propose a new evaluation metric for FLL that is more relevant to FER
