119409 research outputs found
Sort by
Bridging the Gap: Qualities and Professional Development for Diverse Classrooms
No full textBRIDGING THE GAP: Qualities and Professional Development for Diverse Classrooms
(Under the direction of Dr. Rosemary Oliphant-Ingham)
With every year that passes, the diversity found within K-12 public high schools in the United States increases. In order for teachers to work efficiently with students from a range of demographics and cultures, different needs that exist require specific training and education. Previous research identifies universal, innate, and learned qualities of effective teachers, such as empathy, flexibility, positive student-teacher relationships, and vast cultural awareness. There are some previously implemented professional development programs within schools, though limitations arise when looking at how these professionally developed skills and innate traits transfer across educational areas. This study compiled data through (1a) in-class observations, (1b) observed teacher interviews, and (2) self-reported surveys. Results were analyzed via both qualitative and quantitative findings and compared with previously conducted research found in the literature review.
Overall, the study found that teacher effectiveness is determined by the teacher’s ability to connect with students and grow continuously in regard to their needs. Adaptability, empathy, understanding situational respect, and perseverance were found to be universally essential, though how they are expressed depends on situational factors. Effective professional development should be implemented that focuses on reflective practices and culturally responsive teaching. Further, relationship-building practices help to strengthen non-innate qualities to ensure effective and responsive teaching
Investigating The Effects Of Cannabichromene On Different Modalities Of Chemotherapy-Induced Neuropathic Pain
Full text linkChemotherapy is the predominant treatment for a variety of cancers, but throughout its history of use, many side effects have been reported. One of the most common side effects is chemotherapy-induced peripheral neuropathy (CIPN). This side effect subjects an estimated 60% of patients to pain for months to years following chemotherapy. This symptomology is due tothe upregulation of ion channels such as TRPV1, which leads to the release of TNF-α, causing inflammation. These changes manifest in the intraepidermal nerve fibers (IENF), in which chemotherapy damages nociceptors, leading to an overall reduction in density. Current therapeutics, historically limited to opioids or other analgesics, are associated with additional adverse effects, most notably the potential for abuse. Therefore, there is a necessity to develop more effective treatments with fewer risks.
In recent years, cannabinoids have emerged as an alternative to analgesics. Our previous research has shown that cannabichromene (CBC), a minor phytocannabinoid, is capable of alleviating multiple types of pain, while also being devoid of the psychoactive properties of other cannabinoids or the abuse potential of opioids. Given these properties, it was a suitable candidate for assessment against CIPN. We found through the utilization of CIPN mouse models, that CBC was able to attenuate the mechanical sensitivity caused by cisplatin (i.e., mice treated with CBC were less sensitive to mechanical stimulation). While this data provided insightful behavioral outcomes, the cellular mechanisms for this mitigation of CIPN remained unexplored.
As a result, the present study aims to elucidate the specific mechanisms through which CBC mitigates CIPN through optimization of protocols and experimental methods. Hind paws were collected from 6–8-week-old male and female C57BL/6J mice treated with cisplatin (2.3 mg/kg, 6 doses) and vehicle, or cisplatin and CBC (25 mg/kg, single dose). Immunohistochemistry staining protocols were utilized to determine intraepidermal nerve fiber (IENF) density by staining for PGP 9.5 in the hind paws. The acute administration of CBC in male mice that were treated with cisplatin chemotherapy did not show any significant differences in IENF density or in cytokine activation, indicating the possibility for different mechanisms by which CBC attenuates pain
Who Then Can Be Saved? A Discussion of Views Within the Christian Tradition Concerning the Salvation of the Non-Christian
No full textThis thesis argues that, contrary to popular conception, the Christian Tradition is not strictly exclusivist in its understanding of salvation or in its assessment of the fate of the non-Christian but rather displays a rich diversity of views. Both the Christian Tradition and the Christian scriptures are characterized by a certain ambiguity on this issue; although a definitive answer may exist, it is not easily identifiable. Given this ambiguity, the study presents a representative spectrum of theological positions within the Christian Tradition and analyzes their respective treatments of the salvation of the non-Christian. In doing so, it seeks to provide an accessible yet theologically rigorous foundation for renewed discussion of the question: Can the non-Christian be saved according to the Christian Tradition
