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Carboxypeptidase A4 accumulation associated with aggressive phenotype and poor prognosis in triple-negative breast cancer
No full text群馬大学博士（医学）Thesis or Dissertation学位記番号：医博甲1755doctoral thesi
SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels
No full text群馬大学博士（医学）Thesis or Dissertation学位記番号：医博甲1731doctoral thesi
Sex differences in left ventricular afterload and diastolic function are independent from the aortic size.
No full text群馬大学博士（医学）Thesis or Dissertation学位記番号：医博甲1758doctoral thesi
Assessment of NMDA receptor inhibition of phencyclidine analogues using a high-throughput drebrin immunocytochemical assay.
No full text群馬大学博士（医学）Thesis or Dissertation学位記番号：医博甲1760doctoral thesi
STMN1 accumulation is associated with dysplastic and neoplastic lesions in patients with ulcerative colitis
No full text群馬大学博士（医学）Thesis or Dissertation学位記番号：医博甲1775doctoral thesi
Improvement Process of Unconvincing Outcomes in Patients with Parkinson’s Disease Following Deep Brain Stimulation: Analysis of Interview Results using a Modified Grounded Theory Approach (M-GTA)
No full textJournal ArticleBackground & Aims: To obtain a better guide for the nursing care of patients with Parkinson’s disease undergoing longterm care by describing the improvement of unconvincing results after deep brain stimulation (DBS). Methods: Using a modified grounded theory approach, semi-structured interviews were performed with 11 patients (aged 50-80 years) who had undergone 5-14 years of DBS before this study. Results: The improvement process of unconvincing outcomes in patients with Parkinson’s disease following DBS starts with the patients' attempts to share the unconvincing outcomes, followed by repeating the cycle of ambiguity in unconvincing outcomes and becoming saddled with them under maintainable support, and ends in achieving realization of the improvement plan. Conclusions: Patients could hide their unconvincing outcomes from the other patients while struggling for a long time, and they stated that they tried to cope with unconvincing outcomes by reconsidering the meaning of DBS. Its course differs for each person. These findings may be helpful in improving long-term care, enhancing patient satisfaction and quality of life, and in educating patients considering post-DBS care.journal articl
A Case of Unruptured Cerebral Aneurysm Treated with Coil Embolization Associated with Internal Carotid Artery Hypoplasia and an Aberrant Right Subclavian Artery
No full textJournal Article内頚動脈低形成と異所性右鎖骨下動脈に合併した未破裂内頚動脈瘤に対し，コイル塞栓術を施行した症例を経験したので報告する．症例は56歳女性．めまいの精査目的に他院で施行したmagnetic resonance (MR) imagingで左内頚動脈瘤を指摘されたため当院へ紹介となった．初診時，神経学的な異常は認めなかった．脳血管撮影とCT angiographyで右内頚動脈低形成と異所性右鎖骨下動脈を認めた．左内頚動脈瘤の大きさは7.5×5.8 mm，neckは3.6 mmであり，ブレブを伴っていた．破裂予防目的に左内頚動脈瘤に対してバルーン併用下コイル塞栓術を施行した．術中，左内頚動脈の血流遮断を数回要した．左内頚動脈瘤は完全に塞栓され，周術期に有害事象は認めなかった．内頚動脈低形成と異所性右鎖骨下動脈の合併は稀であり，これらの破格を有する症例では血管内手術を行う際，アクセスルートの制限や脳虚血耐性に注意が必要である．journal articl
Laparoscopic Splenectomy for Massive Splenomegaly Accompanied by Malignant Lymphoma: A Two-Case Report
No full textJournal Article腹腔鏡下脾臓摘出術が適応となる悪性疾患，脾腫のサイズに関する明確なエビデンスはないが，技術修練と経験によって遂行可能な症例は腹腔鏡下脾臓摘出術を第1選択とすることが推奨されている．今回我々は悪性リンパ腫による巨脾症例に対して腹腔鏡下脾臓摘出術を施行し得た2例を経験した．症例は40歳代男性と70歳代男性で，CTでの脾臓最大長径は24 cmと21 cmであった．腹腔鏡下脾臓摘出術を完遂し，手術時間は324分と271分，出血量は10 ccと56 cc，摘出脾臓重量は1,500 gと1,550 gであった．病理組織学的診断は脾B細胞性濾胞辺縁帯リンパ腫とマントル細胞リンパ腫の診断であった．いずれも長径20 cmを超える巨脾症例であったが，脾門部の処理を先行して行う前方アプローチで安全に腹腔鏡下に施行し得た．巨脾に対する脾門先行処理による腹腔鏡下脾臓摘出術は有用な方法と考えられた．journal articl
