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Denture Adhesive Used as Gap Filler when Using a Cooling System Installed Microtome: Effects on Preparation of Thin Serial Sections
No full textJournal Article目 的：ミクロトーム連結式パラフィンブロック固定台冷却装置を用いたパラフィンブロックの薄切時連続冷却の有用性を検討した． 方 法：検体のない疑似試料をパラフィンのみで作製し，冷却装置使用時と未使用時のブロック表面温度（温度）測定と連続薄切可能な厚みを検討した．また，その際ブロック裏面の隙間を充填するための義歯安定剤の検討も併せて行った． 結 果：冷却装置を用いると，義歯安定剤充填により一種類を除いてブロック温度は，開始時と 5 分後，開始時と 20 分 後の差が充填なしと比較して有意に大きかったが，20 分後のブロック温度に充填剤の有無で有意差はなかった．また，義歯安定剤充填・冷却条件での薄切は，1 μm 厚まで失敗することなく連続薄切でき，未冷却では，2 μm 厚まで連続薄切できた． 結 論：パラフィンブロックの薄切時持続冷却によって安定した連続薄切が可能であった．journal articl
Pair Bond Formation by Monogamous Prairie Voles in Novel Environments
No full textJournal ArticleBackground: Social bonds between spouses (pair bond) positively affect health conditions. Recently, we reported that the administration of serotonin-selective reuptake inhibitors to monogamous prairie voles ameliorated the impairment of pair bonding caused by traumatic stresses, suggesting the involvement of the serotonergic system in the formation of pair bonds in this model animal. Before investigating this possibility, we investigated the cohabitation condition which leads to a pair bond using our colony of prairie voles.
Methods: Male prairie voles were cohabited with females for 96h in a control experiment. Otherwise, subject males were cohabited with an estradiol-primed females for 6 h or 24h. Subsequently, partner preferences by subject male prairie voles were assessed for 3 h.
Results: All subjects in the 96 h cohabitation group preferred to huddle with their partner than stranger females. Twenty-four hour cohabitation induced partner preference; however a 6-h cohabitation did not, despite accompanying mating bouts.
Conclusions: The formation of pair bonds by prairie voles requires 24 h of cohabitation. Mating bouts in a 6-h cohabitation appear to be insufficient for the formation of a pair bond. Such factors need to be considered when performing experiments using pharmacological methods that enhance or inhibit pair bonds.journal articl
A Case of Bilateral Strangulated Obturator Hernia Treated with Ultrasound Guided Reduction and Elective Laparoscopic Hernia Repair
No full textJournal Article症例は85歳女性．肺炎および心不全で当院救急部にて入院加療を行っていた．リハビリ目的に近医転院となったが，翌日に腹痛の増強あり当院へ再転院となった．両側閉鎖孔ヘルニア嵌頓の診断で，エコーガイド下に嵌頓の解除を行い，10日後に待機的に腹腔鏡下ヘルニア修復術を施行した．術後経過は良好で術後7日目に近医へ転院した．閉鎖孔ヘルニアは高齢で全身状態に問題を抱えている症例も多く，周術期合併症のリスクの高い疾患である．エコーガイド下整復による嵌頓解除で緊急手術を回避し，腹腔鏡下に行うことで確実な診断と治療を行うことが出来た一例を経験したので報告する．journal articl
Fatal Early Recurrence of Peritoneal Mesothelioma after Macroscopic Complete Resection: A Case Report
No full textJournal Article症例は73歳男性で，建設関連の職歴あり．腹部膨満感と食欲不振を主訴に近医を受診し，腹腔内腫瘤の診断で当科紹介となった．腹部CT検査にて回盲部と上行結腸を巻き込む長径200 mmの分葉状腫瘤を認めた．腫瘍による腸閉塞を懸念し，診断的治療目的で結腸右半切除術を施行した．術中所見として，回盲部と上行結腸が一塊となった表面不整，鵞卵大の病変を認めた．小網と小腸間膜の各々50 mm，30 mmの腫瘤を併せて摘出した．その他播種結節は認めなかった．摘出した巨大腫瘍は腸間膜由来であり，広範囲に出血壊死をきたしていたが腸管粘膜に腫瘍成分を認めなかった．組織学的には異型の高度な紡錘形，線維性非上皮性細胞が増殖しており，免疫染色でcalretininが高度陽性となったため腹膜中皮腫の診断に至った．術後経過は良好のため第14病日に退院としたが，腹膜中皮腫の再発により急速に状態が悪化し，第42病日に永眠された．journal articl
Intractable Surgical Site Infection at Drain Site after Appendectomy: A Case Report
No full textJournal Article患者は60歳代，男性．右下腹部痛を主訴に来院した．急性壊疽性虫垂炎，限局性腹膜炎の診断で同日，虫垂切除，ドレナージ術を施行し，骨盤底部に解放式ドレーンを留置した．ドレーンは術後4日目に抜去した．術後経過は良好で術後7日目に退院した．その後，ドレーン抜去部位に手術部位感染Surgical Site Infection（SSI）を発症した．局所麻酔下でデブリードメントを行うと一時的に感染は改善したが，完治しなかった．同部位のSSIは術後1年目まで増悪と改善を繰り返したため，全身麻酔下で瘻孔切除術を施行した．瘻孔は腹壁を完全に貫き小腸壁に索状に癒着していた．小腸内腔とは交通していなかった．今回われわれは解放式ドレーン抜去部に発症し，瘻孔切除術により完治した難治性の腹壁膿瘍の1例について経験したので，文献的考察を加えて報告する．journal articl
Health-related Quality of Life and Potential Barriers to Adequate Nutrition among Japanese Hemodialysis Patients
No full textJournal ArticleBackground and aims:Malnutrition is common in hemodialysis (HD) patients, which is known to reduce theirhealth-related quality of life(QOL). Potential barriers to adequate nutrition can affect a patient’s nutritional status,although whether they also affect the patient’s QOL remains unclear. This study investigated the associationsbetween several potential barriers and QOL among HD patients. M ethods:This cross-sectional study included 36Japanese patients receiving HD for 3 months. The patients completed structured questionnaires regarding anypotential barriers to adequate nutrition. Clinical parameters were evaluated during monthly check-ups. Results:The presence of 1 potential barrier significantly associated with decreased scores in the effect of kidney disease,burden of kidney disease, cognitive function, quality of social interaction, and mental health subscales in theKidney Disease Quality of Life Short Form. Poor knowledge was the most common potential barrier to adequatenutrition. However, difficulty chewing was significantly associated with the greatest number of decreased QOLsubscale scores, even after adjustment for age, suggesting that this barrier has the greatest direct effect on QOL.Conclusions: The presence of 1 potential barrier significantly associated with reduced QOL, indicating theimportance of evaluating potential barriers to adequate nutrition. Further study is necessary to investigate thepossibility that assessment and managing potential barriers improve QOL of patients receiving HD.journal articl
