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Evaluation of pain and flexor reflex responses and their association with clinical parameters in patients with fibromyalgia
No full textObjectives: In the present study, we aimed to evaluate
electrophysiological outcomes of flexor reflexes (FR) emerging in
response to painful stimuli in fibromyalgia (FM) patients.
Patients and methods: This study included a total of 21 female FM
patients (mean age 36.8 +/- 8.0 years; range, 20 to 50 years) and 28
healthy female controls (mean age 37.3 +/- 8.8 years; range, 22 to 53
years). Clinical features of the patients, Fibromyalgia Impact
Questionnaire (FIQ), Beck Depression Inventory (BDI), and Beck Anxiety
Inventory (BAI) scores were recorded. Electrophysiological stimulation
threshold, visual analog scale (VAS) scores of generated pain after each
stimulation, current intensity, flexor responses obtained from muscles,
and electrophysiological measurement of these responses were noted.
Results: The threshold for perception of electrical current was higher
and resistance level to maximum electrical current was lower in FM
patients (p<0.05). The VAS scores of FM patients under maximum
electrical current were higher than the control group (p<0.05), while
the lowest current value in which FR response obtained in FM patients
was lower (p<0.05). The latency was lower, amplitude was higher, and
response area was wider in FM patients (p<0.05). No significant
relationship between the FIQ, BDI, BAI scores and stimulant perception
threshold levels was found in FM patients (p>0.05).
Conclusion: Based on these findings, FR responses may be useful as an
electrophysiological parameter in FM diagnosis
Kitap İncelemesi: Feyzan Erkip’in “Piyasa Yapmanın Yeni Yüzleri: AVM’ler, Sokaklar, Kentler” Başlıklı Çalışması
No full textFlood Analysıs In Çankırı Tatlıçay Stream
No full textBu tez kapsamında Arc-GIS programı kullanılarak, çalışma alanı olarak belirlenen Çankırı
ilinin merkezinden geçen Tatlıçay Deresi’nin havza parametreleri belirlenmiştir. Elde edilen
havza parametrelerine uygun olarak seçilen taşkın hesaplama yöntemleri ile (DSİ Sentetik
Yöntemi ve Bölgesel Taşkın Frekans Analizi) çeşitli tekerrürdeki taşkın debileri
hesaplanmıştır. Taşkın analizleri için oluşturulan arazi modeli, 1/1000 ölçekteki hâlihazır
harita Civil 3D programında işlenerek 3 boyutlu (3D) olarak oluşturulmuş, bu model yine
Civil 3D vasıtası ile hidrolik analizlerin yapılacağı HEC-RAS programına aktarılmıştır.
HEC-RAS programının son versiyonunda, yaygın olarak kullanılan bir boyutlu (1D) akıma
ek olarak, son yıllarda gelişen teknoloji ve yüksek kaliteli veriye erişimin kolaylaşması ile
iki boyutlu (2D) akım analizlerini de yapabilmektedir. Bu çalışma kapsamında Tatlıçay
Deresi HEC-RAS programında 1D ve birleştirilmiş bir ve iki boyutlu (1D-2D) model olmak
üzere iki farklı şekilde analiz edilmiştir. 1D modelde dere ve taşkın yatağı bir boyutlu,1D-
2D modelde ise dere yatağı bir boyutlu, taşkın yatakları iki boyutlu olarak analiz
edilmektedir. 1D, 2D ve 1D-2D modellerinin veri gereksinimleri, kurulum aşamaları ve
modellerden elde edilen sonuçlar karşılaştırılarak aradaki farklar ortaya konmuştur. Bu
çalışmada ayrıca Tatlıçay Deresi üzerinde bulunan 8 adet köprü senaryolar oluşturularak
kademeli olarak düzenlenmiş ve köprülerin taşkın anındaki etkisi irdelenmiştir. Sonuç olarak
1D model yatağın taşkın kapasitesinin bulunmasında yeterli olarak değerlendirilmiş, ancak
ana yatak dışında yayılım alanlarının belirlenmesinde iki boyutlu (2D) analizin gerekli
olduğu sonucuna varılmıştır. Bu sonuca ilave olarak, köprülerin taşkın anındaki olumsuz
etkisi 1D analizde yeterli olarak gözlemlenemezken, köprülerin düzenlenmesiyle birlikte
1D-2D modelde elde edilen yayılım alanlarında 1D modele göre ciddi miktarda azalmalar
belirlenmiştir.In this study, basin parameters of Tatlıçay Stream passing through the city center of Çankırı
province is determined using the software programme Arc-GIS. Flood discharges with
various reoccurrences are calculated by DSİ Synthetic Method and Regional Flood
Frequency Analysis. The land model with a scale of 1/1000 is prepared using Civil 3D and
transferred into HEC-RAS in order to calculate hydraulic analysis. With the latest version
of HEC-RAS, 2D flood analysis can be done in addition to 1D flood analysis. Tatlıçay
Stream is analyzed in two different ways such as 1D and united 1D and 2D models together
using HEC-RAS. Stream and stream bed is analyzed in 1D model. Stream bed is modelled
as one dimensional and floodplain is modelled as two dimensional in united 1D and 2D
models. The differences between 1D, 2D and united 1D-2D models are compared according
to the data requirements, installation stages and the results of the analysis. 8 bridges built on
Tatlıçay Stream are also analyzed and their effect on the flood is discussed. As a result 1D
model is considered to be sufficient to determine the flood capacity of the stream bed but it
is concluded that 2D model is required to determine the propagation areas outside the main
stream bed. In addition to this, the negative impact of bridges while flood occuring cannot
be observed sufficiently in 1D analysis, with the arrangement of the bridges, significant
reductions in the propagation areas obtained according to 1D model in the combined 1D-2D
model were determine
Evaluation of a two-image technique consisting of an axial and a coronal image generated by using the rib-flattening application: effect on reading time and diagnostic validity
No full textBackground/aim: When reading a chest CT, a radiologist needs to evaluate
each rib one by one due to complex curvy shape, which makes reporting a
tiresome and time-consuming task. A new curved planar reformat
application that flattens ribs on a single plane may find a place in the
radiology reporting room. This study aimed to evaluate the effect of a
two-image set created by using the rib-flattening application on the
performance of a radiologist in detecting sclerotic rib lesions in
cancer patients.
Materials and methods: The local Institutional Review Board approved
this retrospective study. Two radiologists with different experience
levels reviewed chest CT examinations of 106 patients (76 men, 30
women). We divided the patients into group A (n = 54), reviewed by a
standard method, and group B (n = 52), reviewed by a standard method and
the two-image set created on the rib-flattening application. Reading
times, validity indices, and agreement levels with reference data were
evaluated for both readers.
Results: The median reading time of the junior examiner significantly
decreased with the rib-flattening method (160.5 s vs. 70.0 s; P <
0.001). Diagnostic indices of the senior reader were improved
significantly at per patient level (group A, AUC: 0.867; group B, AUC:
0.982; P = 0.046). The new method showed better agreement levels (kappa:
0.69 to 0.96) than the general method (kappa: 0.53 to 0.91).
Conclusion: Based on improved agreement levels, reading times, and
diagnostic validity indices we conclude that a two-image set consisting
of an axial and a coronal flattened-rib image may be used in conjunction
with an ordinary exam
Üretim koşullarının 42CrMo4 Çelik matrisli beyaz dökme demir takviyeli kompozitin özelliklerine etkileri
No full textNAUTICAL FESTIVALS IN THE SECOND HALF OF THE 19TH CENTURY: BUYUKADA (PRINKIPO) REGATTAS AND THE TRANSFORMATION OF THE ISLAND
No full textIn the 19th century, specific times of the year were named accordingly
to seasonal changes and / or the activities individuals performed in
their daily (bad season, theatrical season, carnival season and
beautiful season). Regattas, which were maritime / nautical festivals
seen in cities such as London and Marseille, were important urban
actions of the beautiful season of Istanbul. These festivals functioned
as urban social events that span a whole day. The first regatta in
Istanbul was organized in 1859 with the attempts and under the patronage
of British Ambassador Sir Henry Lytton Bulwer in different parts of the
city such as Moda and Buyukdere, yet in time regattas became signature
events of Buyukada.
Regattas attracted the attention of all the citizens, especially the
public officials, diplomats and bankers, namely the high society of
Istanbul. Of the periodicals published in the 19th century, the turnout
in the festivals in the 1870s was about 10,000 people. This very high
level of participation brings into question the existence and extent of
the effect of these events that could have transformed the places where
these particular social events took place. From this perspective, such a
transformative effect of an urban action can be investigated through the
Buyukada regattas. There are no studies on the regattas of Buyukada and
Istanbul in particular. However, the periodicals such as Journal de
Constantinople, Levant Herald, Le Monde Illustre, Levant Herald and
Eastern Express, Servet-i Funun, Malumat and memoirs written by the
individuals like Samuel S. Cox and Lady Hornby who travelled Istanbul in
the 19th century present primary evidence about the events. By applying
these findings onto the Buyukada Map of Antoine Raymund, published in
1912, this paper analyses regattas' major effects on the formation,
transformation and modernization of the urban space in the 19th century
Istanbul
Evaluation of the status quo of polyphenols analysis: Part I—phytochemistry, bioactivity, interactions, and industrial uses
No full text3D printing and spine surgery
No full textRapid prototyping (RP), also known as three-dimensional printing (3DP),
allows the rapid conversion of anatomical images into physical
components by the use of special printers. This novel technology has
also become a promising innovation for spine surgery. As a result of the
developments in 3DP technology, production speeds have increased, and
costs have decreased. This technological development can be used
extensively in different parts of spine surgery such as preoperative
planning, surgical simulations, patient-clinician communication,
education, intraoperative guidance, and even implantable devices.
However, similar to other emerging technologies, the usage of RP in
spine surgery has various drawbacks that are needed to be addressed
through further studies